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Author Topic: high blood pressure the result of PI regime? suggestions?  (Read 5809 times)

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Offline akcol

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  • Posts: 18
high blood pressure the result of PI regime? suggestions?
« on: June 15, 2006, 01:50:57 PM »
Hi All,
Is anyone registering high blood pressure as a direct result of NNRTI or PI based HAART?
My fiance, with HIV since 1983, on a recent new HAART switch regime: (Reyataz, Combivir, Norvir for two months) from Sustiva and Combivir, (two years) has been registering high blood pressure for a few months now. He does take medication for asthma, and infuses with Factor 8 products for Hemophilia.  We are aware that all of these medications can cause high blood presuure, let alone the daily stress of our particular lives with these challenges.
We're working on improving this particular aspect of health right now, and wonder if others are experiencing high blood pressure relief from additional health lifestyle measures or blood pressure medications that will work with Reyataz/Combivir/Combivir?
Thank you for your help, and best health to you!

Offline newt

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Re: high blood pressure the result of PI regime? suggestions?
« Reply #1 on: June 16, 2006, 09:39:18 AM »
Your hubby's blood pressure is less to be related directly to his current combo than his age, body mass index and stuff like smoking. 

Increased blood pressure does happen though for people on combo long-term, sometimes realted to diabetes and changes in (lipids) blood fats, which can be causes by some combos, and also by having HIV long-term perhaps.  No-one is quite sure....  Reyataz is the most favourable PI re: blood pressure increases etc (chances are 5 x less likely than Kaletra, for example), and generally good on lipids.  Sustiva, however, raises triglycerides, and these might take a while to drop after a switch.

- matt
"The object is to be a well patient, not a good patient"

Offline chrism1973

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Re: high blood pressure the result of PI regime? suggestions?
« Reply #2 on: June 19, 2006, 06:40:18 AM »
what meds is your other half on for asthma?? I know flovent and reyataz have a med interaction that will raise the blood pressure.I was on that when i wnet to a PI based regimen and had to stop the flovent.
Love yourself,love life and live.

Offline doyourowndamndishes

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Re: high blood pressure the result of PI regime? suggestions?
« Reply #3 on: June 19, 2006, 10:27:57 AM »
Hey akcol,

I've been on PI therapy for 5 years now and never have had a problem with high blood pressure.  In fact, I have extremely low blood pressure (get dizzy if I stand up too quickly and crap like that). The PIs did screw up my hdl, ldl and tryglicerides till I switched Kaletra for Atazanavir.  Fish oils can help but not sure about the BP.  Diet, exercise, smoking and other "lifestyle" choices may be more of a factor as Matt had previously mentioned. 

Sorry, I wish I could be of more help.


"All that we are is theresult of what we have thought." -Buddha

Offline allopathicholistic

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Re: high blood pressure the result of PI regime? suggestions?
« Reply #4 on: June 19, 2006, 11:24:28 AM »
re; asthma

during the time i was on reyataz the doc thought it fine to give me an Rx for


it's a fast acting inhaler a.k.a. bronchodialator

Offline akcol

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  • Posts: 18
Re: high blood pressure the result of PI regime? suggestions?
« Reply #5 on: July 22, 2006, 11:19:18 AM »
the ashtma meds may be the culprit, having switched from Advair to Serevent and a second inhaler - the name of which I can't think of at this moment. He uses Flonase as well, and for our extreme allergy season here, a claritin D.

Something is making his heartwork more, and he's getting higher and higher pressure. Which he thinks add to the stress, which in turn, increases heart rate.
Beyond the crazy crisis we al go through with such sets of challenges, dealing with them with grace and strength, we may look for blood pressure med to give his heart a break.
Any recommendations and cautions with this therapy: Combiir, Reyataz, Norvir re: high blood pressure?

Also, Reyataz jaundice aside, how about this signicifant weight gain on his face and belly. Wow. It just showed up at about the two weeks off mark from the susutiva swutch, into his present Pi based regimez: reyataz and norvir/combivr regime.

Thanks, and have a better day


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