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Author Topic: On average how long does a certain drug last?  (Read 2297 times)

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Offline Ihavehope

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On average how long does a certain drug last?
« on: January 10, 2007, 10:44:03 AM »
Just curious to know how long a regimen of drugs last?
Infected: April 2005
12/6/06 - Diagnosed HIV positive
12/19/06 - CD4 = 240  22% VL = 26,300
1/4/07 - CD4 = 200 16% VL = ?
2/9/07 = Started Kaletra/Truvada
3/13/07 = CD4 = 386 22% VL ?

Offline penguin

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Re: On average how long does a certain drug last?
« Reply #1 on: January 10, 2007, 11:59:56 AM »
As with most things in life, there are no guarantees.
However, current evidence would suggest that provided viral load remains undetectable (ie,<50) and adherence is maintained, a well chosen combo will continue to work for a long time, possibly indefinitely.

I know that when you are first diagnosed, there are  lots of worries to deal with, both about the right now and the future. I think you can expect that as and when you do decide to start treatment, whether that is soon or several years down the line, the meds will work - and keep working, as long as you take them on time and as prescribed.

For some (plain english) info about starting treatment etc : i-base

It takes a while, but you do get to a point where it all becomes smaller, less intrusive, both  in the headspace and day to day business of life.


Offline koi1

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Re: On average how long does a certain drug last?
« Reply #2 on: January 10, 2007, 11:02:41 PM »
I asked the ID team at the hospital where I get treated, and they said they have patients who have been on the same regimen for 10 years or more. Some people only change because something better comes along, or sometimes they do develop drug resistance. They say that it is on the rare side that someone who adheres to treatment guidelines developes drug resistance. They say they have encountered superinfection though which does complicate things.

diagnosed on 11/20/06 viral load 23,000  cd4 97    8%
01/04/07 six weeks after diagnosis vl 53,000 cd4 cd4 70    6%
Began sustiva truvada 01/04/07
newest labs  drawn on 01/15/07  vl 1,100    cd4 119    7%
Drawn 02/10/07
cd4=160 viral load= 131 percentage= 8%
New labs 3/10/07 (two months on sustiva truvada
cd4 count 292  percentage 14 viral load undetectable


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