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Author Topic: Sun exposure and viral load  (Read 479 times)

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Offline an92

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Sun exposure and viral load
« on: July 18, 2020, 11:24:04 am »
As you know now its summer, and here in Switzerland its quite hot, with 30 degrees and sunshine every day.
Ive read some info online (i wonder if itís outdated), that exposure to strong sun can interfere withe the pills and affect viral load. In fact in Russia mainstream doctors who say that Hiv positive people must avoid the sun. I wonderif itís all bull, I suspect it is, never had my doc here Mention anything.
I wanted to go hiking tomorrow, so will be exposed to strong sun most of the day.

Offline virgo313

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Re: Sun exposure and viral load
« Reply #1 on: July 18, 2020, 11:43:11 am »
Is the article you read refer to pills expose to direct sunlight?
RVD Nov 2015. VL --> Log 5.32 HAART on 23/11/15
TDF+FTC+EFV / Chemo KS - 25/11/15 - 20/01/16.
CD4 - 4 (3/11/15) / VL - 225,000

Offline an92

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Re: Sun exposure and viral load
« Reply #2 on: July 18, 2020, 12:00:30 pm »
No no, i mean going in the sun. Tanning for example, or just many hours of sun exposure

Offline Jim Allen

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Re: Sun exposure and viral load
« Reply #3 on: July 18, 2020, 01:10:17 pm »
Never heard that, heard the opposite in terms of VitD and it's role. If a few hours of sunlight would undo HIV supression so virologic failure we would all be fucked and I've never seen a paper on virologic failure list sunlight as a reason.

Would be extremely surprised if there is any merit to this claim, i.e I suspect whatever you read is bullshit or out of context, provide us a link and we can have a look.

Jim

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148856/
« Last Edit: July 18, 2020, 01:15:29 pm by Jim Allen »
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Offline virgo313

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Re: Sun exposure and viral load
« Reply #4 on: July 18, 2020, 01:15:42 pm »
Too much sun tanning without protection over a long period of time is not good for the skin.
RVD Nov 2015. VL --> Log 5.32 HAART on 23/11/15
TDF+FTC+EFV / Chemo KS - 25/11/15 - 20/01/16.
CD4 - 4 (3/11/15) / VL - 225,000

Offline Jim Allen

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Re: Sun exposure and viral load
« Reply #5 on: July 18, 2020, 01:19:56 pm »
Too much sun tanning without protection over a long period of time is not good for the skin.

Yeah, not great for the health considering cancer etc.
https://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
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Offline J.R.E.

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Re: Sun exposure and viral load
« Reply #6 on: July 18, 2020, 02:02:09 pm »
Hello An92,

I've also never heard of warnings about the sun and HIV medications.  However, there are medications that when taken you should avoid or limit sun exposure. See the link below:

I lived here in Florida with HIV for 35 years, and the sun never affected my viral load, But it has given me some basal cell skin cancer that I keep in check.



https://www.health.harvard.edu/skin-and-hair/10-types-of-medications#:~:text=You%20should%20take%20extra%20precautions,%2C%20or%20tetracycline%20(Achromycin

How drugs magnify the sun's effects
Some drugs contain compounds that, when activated by the sun's ultraviolet A (UVA) radiation, can damage cell membranes and, in some instances, DNA. The result can be a severe, blistering sunburn on the exposed parts of the body. Less frequently, drugs may trigger an allergic reaction to sun exposure, producing a rash that can cover the entire body.

Certain medications make it more difficult to withstand the heat, increasing the risk of sunstroke. The drugs may constrict blood vessels, which interferes with your ability to cool off by sweating, or they may affect the brain's ability to regulate body temperature.

The following categories of drugs are particularly likely to increase your sensitivity to the sun's effects.

1. Antibiotics. You should take extra precautions against the sun if you're taking any of the following: ciprofloxacin (Cipro, ProQuin), doxycycline (Oracea, Vibramycin), sulfamethoxazole (Bactrim, Gantanol, Septra), or tetracycline (Achromycin).

2. Cancer drugs. Chemotherapy agents that target skin cancers or precancerous conditions also increase sun sensitivity. They include 5-fluorouracil (Carac, Efudex, Fluoroplex), dacarbazine (DTIC-Dome), and vemurafenib (Zelboraf).

3. Decongestants and older antihistamines. Pseudoephedrine (Sudafed), phenylephrine (Sudafed PE), and diphenhydramine (Benadryl) and constrict blood vessels and make you more susceptible to overheating. For a cold or allergy, better alternatives are fexofenadine (Allegra) and loratadine (Claritin).

4. Diabetes medications. Some drugs to lower blood sugar increase sun susceptibility, including chlorpropamide (Diabinese) and glyburide (DiaBeta, Glynase, Micronase).

5. Diuretics. Certain drugs, particularly furosemide (Lasix) and hydrochlorothiazide (Microzide), may increase sun sensitivity and raise the risk of dehydration.

6. Cardiovascular medications. Amiodarone (Cordarone), for serious heart rhythm disturbances, and the blood pressure drugs diltiazem (Cardizem, Dilacor, Tiazac) and nifedipine (Procardia) increase sun sensitivity.

7. Hormones. Oral contraceptives and postmenopausal hormone therapy may cause melisma ó dark patches on the forehead, cheeks, or chin ó in some women. Melasma is intensified by exposure to the sun's light and heat.

8. Drugs for skin conditions. Retinoids ó including the oral medications acitretin (Soriatane) for psoriasis and isotretinoin for acne ó increase the skin's sensitivity to the sun. So does tretinoin, a retinoid that is applied to the skin to treat acne (as Retin-A) or erase fine lines (as Renova). Apply tretinoin creams at bedtime so that your skin can absorb them overnight.

9. Pain relievers. Nonsteroidal anti-inflammatory drugs like ibuprofen (Motrin), naproxen (Aleve, Naprosyn), celecoxib (Celebrex), and piroxicam (Feldene) increase the likelihood of a serious sunburn. However, acetaminophen (Tylenol) doesn't.

10. Psychiatric drugs. Chlorpromazine (Thorazine), desipramine (Norpramin), imipramine (Tofranil), and other anti-anxiety and antidepressant drugs can increase susceptibility to sunburn and inhibit the body's ability to sweat.

Ray
« Last Edit: July 18, 2020, 02:07:10 pm by J.R.E. »
Current Meds ; Viramune / Epzicom , 20 mg of Atorvastatin, 25 mg of Hydrochlorothiazide.
Amlodipine Besolate 5mg-- Updated 7/15/20

Diagnosed positive in 1985,.. In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started on  HAART on October 24th, 2003.

 As of July 8th,20,  Viral load remains Undetectable

CD 4 @589 /  CD4 % @ 17 %
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Offline elf

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Re: Sun exposure and viral load
« Reply #7 on: July 18, 2020, 02:59:39 pm »
Sun exposure acts imunossupressive, by making interleukin-6 go up.
This is good for some illnesses, like psoriasis, but not that good for HIV infection.

Offline fabio

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Re: Sun exposure and viral load
« Reply #8 on: July 18, 2020, 08:28:07 pm »
I don't think it has to do much with hiv,but wearing sunscreen is important (although I sometimes feel bored to). It seems we are,in that part,at the same risk as most people,especially if you live in a country that is very sunny.

Offline an92

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Re: Sun exposure and viral load
« Reply #9 on: July 24, 2020, 03:31:27 pm »
Never heard that, heard the opposite in terms of VitD and it's role. If a few hours of sunlight would undo HIV supression so virologic failure we would all be fucked and I've never seen a paper on virologic failure list sunlight as a reason.

Would be extremely surprised if there is any merit to this claim, i.e I suspect whatever you read is bullshit or out of context, provide us a link and we can have a look.

Jim

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148856/

Hi Jim thanks for the reply, I canít provide a link unfortunately as it is just stuff Iíve read on a russian HIV forum, quite similar to this one, but there were doctors answering in the thread and they said to avoid the sun, tanning and beach holidays. Again maybe itís a cultural thing, because Iíve never heard that advice in the UK and in Switzerland. And if youíve never heard that, then probably it really is nothing then. Just stories about people going on holidays to hot countries and lying on beaches and then returning back to find half of their CD4s are gone. Judging from the other replies here (thanks for the replies) I see that others havenít come across this either, so Iím going to disregard that and continue to enjoy the summer sun on my daily walks!
« Last Edit: July 24, 2020, 04:11:44 pm by Jim Allen »

Offline an92

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Re: Sun exposure and viral load
« Reply #10 on: July 24, 2020, 03:32:59 pm »
Sun exposure acts imunossupressive, by making interleukin-6 go up.
This is good for some illnesses, like psoriasis, but not that good for HIV infection.

Hi, any link to that info? are you saying we canít go in the sun? What if you live in a country with hot summers. I always thought that sun was actually good for the immune system and for health in general

Offline Jim Allen

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Re: Sun exposure and viral load
« Reply #11 on: July 24, 2020, 04:08:47 pm »
Quote
I see that others havenít come across this either, so Iím going to disregard that and continue to enjoy the summer sun on my daily walks!

Yeah, I've searched as well in scholar and found nothing, not a single case mentioned of HIV virologic failure due to or contributed by sunlight, if it was true it would be known.

I would disregard this as yet another myth or someone taking a Petri dish result or immune response result and twisting/mistakenly thinking it translates to something else when it doesn't.

P.s.

Enjoy the sun, wear sunscreen of course, plenty of other health issues it can cause.

https://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
« Last Edit: July 24, 2020, 07:52:26 pm by Jim Allen »
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
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Read about PEP and PrEP here
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