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Author Topic: Early antiretroviral (ARV) treatment can reduce viral reservoirs  (Read 897 times)

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Offline Jim Allen

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It's confirming what was already suspected and, in part, seen in other studies. Early treatment reduces viral reservoirs size.

https://www.poz.com/article/treating-hiv-early-can-shrink-viral-reservoir-100fold

Quote
When people with HIV begin antiretroviral (ARV) treatment within weeks of infection, their viral reservoirs can be reduced by 99%, a new study has found. Although HIV begins to establish a viral reservoir very soon after infection, during the earliest phases the reservoir remains susceptible to ARVs.

Quote
"Although the viral reservoirs from these early treated people are extremely small,” Chomont continued, “the virus is still there, and one might say there is no immediate clinical benefit for now. Nonetheless, since these early treated individuals have viral reservoirs 100 times smaller compared to our control group, we could reasonably think that it will be easier to eradicate these mini reservoirs than the large reservoirs in people who started ART later.”

Those who started ARVs during Fiebig stages IV or V experienced only a slight decline in the frequency of HIV infection in their cells.
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