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Author Topic: Time to Switch Meds - Genvoya or Biktarvy  (Read 1413 times)

0 Members and 1 Guest are viewing this topic.

Offline next2u

  • Member
  • Posts: 1,813
Time to Switch Meds - Genvoya or Biktarvy
« on: October 24, 2019, 01:08:01 pm »
Hello Friends,

My long term HIV doctor retired last years and a new doctor came to our facility. The new doctor wants me to change HIV meds. I have been on 2 regiments, Atripla and Stribild. The switch from Atripla to Stribild was life changing. The morning fog disappeared and my a.m. enthusiasm returned after more than a few years.

The doctor recommended either Genvoya or Biktarvy. Does anyone have experience with either? Does anyone have a recommendation or info about either?
 
full list of options:

Atripla - No
Complera - No
Stribild - Current
Odefsey -
Genvoya - Recommended
Triumeq -
Juluca -
Biktarvy - Recommended

`d
midapr07 - seroconversion
sept07 - tested poz
oct07 cd4 1013; vl 13,900; cd4% 41
feb08 cd4  694;  vl 16,160; cd4% 50.1
may08 cd4 546; vl 91,480; cd4% 32
aug08 cd4 576; vl 48,190; cd4% 40.7
dec08 cd4 559; vl 63,020; cd4% 29.4
feb09 cd4 464; vl 11,000; cd4% 26
may09 cd4 544; vl 29,710; cd4% 27.2
oct09 cd4 ...; vl 23,350; cd4% 31.6
mar10 cd4 408; vl 59,050; cd4% 31.4
aug10 cd4 328; vl 80,000; cd4% 19.3 STARTED ATRIPLA
oct10 cd4 423; vl 410 ;); cd4% 30.2
jun11 cd4 439; vl <20 ;); cd4% 33.8 <-Undetectable!
mar12 cd4 695; vl ud; cd4% 38.6
jan13 cd4 738; vl ud; cd4% 36.8
aug13 cd4 930; vl ud; cd4% 44.3
jan14 cd4 813; vl ud; cd4% 42.8
may14 cd4 783; vl *; cd4%43.5
sept14 cd4 990; vl ud; cd4% *
jun15 cd4 1152; vl ud; cd4% *
july15 - STRIBILD
oct15 cd4 583; vl 146; cd4% 42
mar16 cd4 860; vl 20; 44

Offline next2u

  • Member
  • Posts: 1,813
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #1 on: October 24, 2019, 01:10:58 pm »
Hi All,

My new ID dr wants me to change meds. He gave me the options below. Your thoughts?

Atripla - No
Complera - No
Stribild - Current medication
Odefsey - ?
Genvoya - Recommended
Triumeq - ?
Juluca - ?
Biktarvy - Recommended

`d
midapr07 - seroconversion
sept07 - tested poz
oct07 cd4 1013; vl 13,900; cd4% 41
feb08 cd4  694;  vl 16,160; cd4% 50.1
may08 cd4 546; vl 91,480; cd4% 32
aug08 cd4 576; vl 48,190; cd4% 40.7
dec08 cd4 559; vl 63,020; cd4% 29.4
feb09 cd4 464; vl 11,000; cd4% 26
may09 cd4 544; vl 29,710; cd4% 27.2
oct09 cd4 ...; vl 23,350; cd4% 31.6
mar10 cd4 408; vl 59,050; cd4% 31.4
aug10 cd4 328; vl 80,000; cd4% 19.3 STARTED ATRIPLA
oct10 cd4 423; vl 410 ;); cd4% 30.2
jun11 cd4 439; vl <20 ;); cd4% 33.8 <-Undetectable!
mar12 cd4 695; vl ud; cd4% 38.6
jan13 cd4 738; vl ud; cd4% 36.8
aug13 cd4 930; vl ud; cd4% 44.3
jan14 cd4 813; vl ud; cd4% 42.8
may14 cd4 783; vl *; cd4%43.5
sept14 cd4 990; vl ud; cd4% *
jun15 cd4 1152; vl ud; cd4% *
july15 - STRIBILD
oct15 cd4 583; vl 146; cd4% 42
mar16 cd4 860; vl 20; 44

Offline Jim Allen

  • Administrator
  • Member
  • Posts: 15,145
  • Twitter @JimAllenDublin
    • HIV Lessons
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #2 on: October 24, 2019, 01:40:34 pm »
For me combo's containing TDF/TAF would not work, so "Juluca" or "Triumeq" would be my choice and I'm currently already on "Triumeq"

Quote
My new ID dr wants me to change meds. He gave me the options below. Your thoughts?

Why?
HIV 101 - Everything you need to know
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Read about PEP and PrEP here
PEP and PrEP

Offline Grasshopper

  • Member
  • Posts: 589
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #3 on: October 25, 2019, 08:55:04 am »
Regarding the 1 pill regiments, I started with Stribild, followed by Genvoya and currently on Biktarvy.


I started in 1992 with AZT and tried countless meds after. I remember in the past just looking at some of the pills made me sick to the stomach. Biktarvy is the BEST.....no issues whatsoever.

Offline next2u

  • Member
  • Posts: 1,813
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #4 on: October 26, 2019, 12:49:32 am »
Thank you both. I have an appt with my dr next week. I had to look up TAF vs TDF. I don't think i have issues with either. I saw that Genvoya was like Stribild but kinder on the internals.

I had a few blips with Stribild. I occasionally miss a dose, like once or twice a month. it just happens and i'm not sure if it contributed to the blips. I went from undetectable to detectable but it was still a relatively small vl.

my dr described Biktarvy as hiv meds on steroids and he made it sound like the latest and greatest.

I am still undecided on which one but i know i will make the switch! I like both options at this time. I do have higher cholesterol. it is borderline high. I saw that one of the meds was better on cholesterol. i saw that another user had some side effects from the biktarvy. i think he said he was lethargic and possibly foggy. not sure.

i have a few more days to look into it. dont know. i guess if i dont like one i can switch to the other.

~d
midapr07 - seroconversion
sept07 - tested poz
oct07 cd4 1013; vl 13,900; cd4% 41
feb08 cd4  694;  vl 16,160; cd4% 50.1
may08 cd4 546; vl 91,480; cd4% 32
aug08 cd4 576; vl 48,190; cd4% 40.7
dec08 cd4 559; vl 63,020; cd4% 29.4
feb09 cd4 464; vl 11,000; cd4% 26
may09 cd4 544; vl 29,710; cd4% 27.2
oct09 cd4 ...; vl 23,350; cd4% 31.6
mar10 cd4 408; vl 59,050; cd4% 31.4
aug10 cd4 328; vl 80,000; cd4% 19.3 STARTED ATRIPLA
oct10 cd4 423; vl 410 ;); cd4% 30.2
jun11 cd4 439; vl <20 ;); cd4% 33.8 <-Undetectable!
mar12 cd4 695; vl ud; cd4% 38.6
jan13 cd4 738; vl ud; cd4% 36.8
aug13 cd4 930; vl ud; cd4% 44.3
jan14 cd4 813; vl ud; cd4% 42.8
may14 cd4 783; vl *; cd4%43.5
sept14 cd4 990; vl ud; cd4% *
jun15 cd4 1152; vl ud; cd4% *
july15 - STRIBILD
oct15 cd4 583; vl 146; cd4% 42
mar16 cd4 860; vl 20; 44

Offline Expat1

  • Member
  • Posts: 321
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #5 on: October 26, 2019, 09:41:45 am »
Biktarvy does not need a booster.  Genvoya does.   So I think I would go with the one without the booster.  Good luck.

Offline next2u

  • Member
  • Posts: 1,813
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #6 on: October 26, 2019, 02:54:19 pm »
Thanks! earlier i was looking for more of the same - Genvoya. Now I think I'm going to switch to Biktarvy.

I'll talk to my provider about this next week and make the call then ;)
midapr07 - seroconversion
sept07 - tested poz
oct07 cd4 1013; vl 13,900; cd4% 41
feb08 cd4  694;  vl 16,160; cd4% 50.1
may08 cd4 546; vl 91,480; cd4% 32
aug08 cd4 576; vl 48,190; cd4% 40.7
dec08 cd4 559; vl 63,020; cd4% 29.4
feb09 cd4 464; vl 11,000; cd4% 26
may09 cd4 544; vl 29,710; cd4% 27.2
oct09 cd4 ...; vl 23,350; cd4% 31.6
mar10 cd4 408; vl 59,050; cd4% 31.4
aug10 cd4 328; vl 80,000; cd4% 19.3 STARTED ATRIPLA
oct10 cd4 423; vl 410 ;); cd4% 30.2
jun11 cd4 439; vl <20 ;); cd4% 33.8 <-Undetectable!
mar12 cd4 695; vl ud; cd4% 38.6
jan13 cd4 738; vl ud; cd4% 36.8
aug13 cd4 930; vl ud; cd4% 44.3
jan14 cd4 813; vl ud; cd4% 42.8
may14 cd4 783; vl *; cd4%43.5
sept14 cd4 990; vl ud; cd4% *
jun15 cd4 1152; vl ud; cd4% *
july15 - STRIBILD
oct15 cd4 583; vl 146; cd4% 42
mar16 cd4 860; vl 20; 44

Offline phoenix

  • Member
  • Posts: 77
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #7 on: October 26, 2019, 06:50:47 pm »
Hi next2u     I switched to Biktarvy  in  September and have had no problems. I like that its one pill a day and don't have to take it with food. Good luck
A positive attitude may not solve all your problems but it will annoy enough people to make it worthwhile.                              The point of the journey is not to arrive.

Offline next2u

  • Member
  • Posts: 1,813
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #8 on: October 27, 2019, 02:48:27 pm »
thank you. I am looking forward to going that route.

Jim - sorry for missing your question earlier. My doctor suggested it because there are new medicines that are easier on the body. He said something about my medicine, Stribild, being older and that there were new, more effective regiments with less impacts on bones and kidneys. or something to that effect. I don't think he saw the recent blips, that had me going from undetectable to small vl.

I also didnt talk to him about other concerns i had. I will bring them up during our next visit. thanks for the response. it prompted me to do more digging. Have a good day :)

~d
midapr07 - seroconversion
sept07 - tested poz
oct07 cd4 1013; vl 13,900; cd4% 41
feb08 cd4  694;  vl 16,160; cd4% 50.1
may08 cd4 546; vl 91,480; cd4% 32
aug08 cd4 576; vl 48,190; cd4% 40.7
dec08 cd4 559; vl 63,020; cd4% 29.4
feb09 cd4 464; vl 11,000; cd4% 26
may09 cd4 544; vl 29,710; cd4% 27.2
oct09 cd4 ...; vl 23,350; cd4% 31.6
mar10 cd4 408; vl 59,050; cd4% 31.4
aug10 cd4 328; vl 80,000; cd4% 19.3 STARTED ATRIPLA
oct10 cd4 423; vl 410 ;); cd4% 30.2
jun11 cd4 439; vl <20 ;); cd4% 33.8 <-Undetectable!
mar12 cd4 695; vl ud; cd4% 38.6
jan13 cd4 738; vl ud; cd4% 36.8
aug13 cd4 930; vl ud; cd4% 44.3
jan14 cd4 813; vl ud; cd4% 42.8
may14 cd4 783; vl *; cd4%43.5
sept14 cd4 990; vl ud; cd4% *
jun15 cd4 1152; vl ud; cd4% *
july15 - STRIBILD
oct15 cd4 583; vl 146; cd4% 42
mar16 cd4 860; vl 20; 44

Offline BlueMoon

  • Member
  • Posts: 680
  • Calling from the Fun House
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #9 on: October 28, 2019, 12:40:21 am »
I have been taking Biktarvy since January with no apparent side effects.  My main reasons for switching after nine years were for once a day dosing, and for the newer version of tenofovir.

I would not switch a tolerable and successful regimen unless there is a clear benefit.  I think that sometimes doctors have ulterior motives for recommending new meds, especially when they are taking over treatment from other doctors; those motives can include ego and financial incentives.  Make sure a change is what is best for you.
It's a complex world

Offline next2u

  • Member
  • Posts: 1,813
Re: Time to Switch Meds - Genvoya or Biktarvy
« Reply #10 on: October 28, 2019, 11:27:20 am »
well said. ive seen that happen and did not even consider it here. i don't feel that is this doctor's motive but i will look into it more. i should have considered it.

the concerns ive had that should have prompted the move werent really addressed. it was more, new technology, less long term collateral health impacts.

~d
midapr07 - seroconversion
sept07 - tested poz
oct07 cd4 1013; vl 13,900; cd4% 41
feb08 cd4  694;  vl 16,160; cd4% 50.1
may08 cd4 546; vl 91,480; cd4% 32
aug08 cd4 576; vl 48,190; cd4% 40.7
dec08 cd4 559; vl 63,020; cd4% 29.4
feb09 cd4 464; vl 11,000; cd4% 26
may09 cd4 544; vl 29,710; cd4% 27.2
oct09 cd4 ...; vl 23,350; cd4% 31.6
mar10 cd4 408; vl 59,050; cd4% 31.4
aug10 cd4 328; vl 80,000; cd4% 19.3 STARTED ATRIPLA
oct10 cd4 423; vl 410 ;); cd4% 30.2
jun11 cd4 439; vl <20 ;); cd4% 33.8 <-Undetectable!
mar12 cd4 695; vl ud; cd4% 38.6
jan13 cd4 738; vl ud; cd4% 36.8
aug13 cd4 930; vl ud; cd4% 44.3
jan14 cd4 813; vl ud; cd4% 42.8
may14 cd4 783; vl *; cd4%43.5
sept14 cd4 990; vl ud; cd4% *
jun15 cd4 1152; vl ud; cd4% *
july15 - STRIBILD
oct15 cd4 583; vl 146; cd4% 42
mar16 cd4 860; vl 20; 44

 


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