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Author Topic: U=U  (Read 707 times)

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Offline Smiley22

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U=U
« on: October 03, 2019, 06:51:32 pm »
Hello everyone I was just reading up on all the new information about U=U and I already had a lot of knowledge on the subject. I was just coming to the forums to see what you all think about it?
I also wanted to know how many of you use that as a form of prevention or protection and how effective it is.

Offline harleymc

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Re: U=U
« Reply #1 on: October 03, 2019, 07:50:18 pm »
There have been study after study on this that have shown no transmission of HIV if the viral load is supressed. None whatsoever once the viral load is supressed for six months continuously.

The first study to indicate this was from Uganda, with less than 1500 as the cut off for undetectable. But it was a small study so maybe not as evidentiary as the later ones.

HTPN 052 found no transmission with VL < 200 ( for 6 months or more), Other studies have shown the same 'Opposites Attract', 'Partner' and 'Partner2' studies.

I think it's great, it's really blasted any lingering self stigma from my mind. I am not a disease vector, I am not a risk to anyone I choose to be intimate with.

Online Jim Allen

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Re: U=U
« Reply #2 on: October 03, 2019, 08:00:09 pm »
Quote
I was just reading up on all the new information

What were you reading??

Quote
what you all think about it?

It's okay I suppose ... doesn't fix or change anything for me personally at this stage or resolve the type of stigma I come across but it's great for a lot of people's peace of mind I guess.

Quote
how effective it is.
TaSP overall is scientifically interesting and pretty effective considering there has not been a sexually transmitted case recorded whilst being UD* and the concept comes with nearly 21+ years of evidence to support it both through observational data and controlled studies.

Jim

*6+ months undetectable as in less than 200 copies/milliliter

Castilla J et al. Effectiveness of highly active antiretroviral therapy in reducing heterosexual transmission of HIV. J Acquir Immune Defic Syndr 40: 96-101, 2005

Overview with the more key research/findings from the 21 odd years (there is even more though)
http://i-base.info/htb/32308

Vernazza P et al. Bulletin des médecins suisses 89 (5), 30 January 2008

https://www.preventionaccess.org/consensus
« Last Edit: October 04, 2019, 03:03:47 am by Jim Allen »
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline leatherman

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Re: U=U
« Reply #3 on: October 03, 2019, 08:22:20 pm »
see what you all think about it?
we'll never treat ourselves out of this disease (with TasP and PrEP) but every reduction in transmission gets us closer to ending the HIV epidemic.
leatherman (aka mIkIE)


chart from 1992-2017
Tivicay/Prezcobix

Online Jim Allen

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Re: U=U
« Reply #4 on: October 03, 2019, 09:08:33 pm »
every reduction in transmission gets us closer to ending the HIV epidemic.

Very true.
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline Smiley22

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  • Posts: 7
Re: U=U
« Reply #5 on: October 03, 2019, 09:15:00 pm »
we'll never treat ourselves out of this disease (with TasP and PrEP) but every reduction in transmission gets us closer to ending the HIV epidemic.

So you think U=U or TaSP is effective? If it’s used the right way ?
« Last Edit: October 03, 2019, 09:16:20 pm by Jim Allen »

Online Jim Allen

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Re: U=U
« Reply #6 on: October 03, 2019, 09:17:32 pm »
FYI; I edited & fixed the quote in your post for you.

I would say the evidence is clear on TaSP (U=U)
« Last Edit: October 03, 2019, 09:20:05 pm by Jim Allen »
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline leatherman

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  • Posts: 7,717
  • Google and HIV meds are Your Friends
Re: U=U
« Reply #7 on: October 04, 2019, 07:17:01 am »
So you think U=U or TaSP is effective?
I don't have to "think" about U=U because the science is overwhelming. If you have been UD for at least 6 months you don't have enough viable HIV to transmit HIV.

If it’s used the right way ?
what usage are you talking about? There is no "wrong way". If you have HIV, you need to have treatment/medication. If you adhere to your meds, you will become UD. If you are UD for 6 months, you CAN NOT transmit HIV (basically because you don't have enough HIV left in you to transmit) through unprotected sex (of course, you can still transmit other diseases or STIs but not HIV)


we'll never treat ourselves out of this disease
we'll never treat ourselves out of this disease because not every one infected will be tested and treated in time to stop all transmissions. And in many countries (sadly including America) not everyone infected with HIV has access to health care to get proper treatment in time and to continue treatment, so those are possible vectors for transmission.

In America, there are approximately 50k newly diagnosed HIV infections every year. If TasP/PrEP reduces that to 2000, the epidemic won't be ended but that kind of reduction would certainly be a game changer. And that's why its so important to get those who might be at risk tested and if positive treated. ASOs and the Ryan White Care Program have worked hard for decades trying to get more people tested, more people treated early, and more people to remain adherent, and we have tons of scientific proof (agency and statewide data) that TasP/PrEP work.

If you're in America, find out if your provider receives Ryan White funding. If they do, they should have a "client advisory committee" where you can find out more information about your provider's agency and the state for getting people tested and treated. Also every state is currently working on an "Ending the Epidemic" project and that working committee should be able to give you more information about how TasP/PrEP are reducing HIV in your state
leatherman (aka mIkIE)


chart from 1992-2017
Tivicay/Prezcobix

 


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