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Author Topic: Data sharing: tested positive in March  (Read 1626 times)

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Offline rajagidh

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Data sharing: tested positive in March
« on: April 24, 2019, 07:11:40 pm »
It's true that I had a hard time during the first week, and later on because all my partners reported to be either on PrEP or undetectable. On the other hand, I've also had immense support from friends, colleagues and family (the select few I revealed my status to).

I love this site because, apart from sharing their fears and feelings, folks share data about their bodies and well-being. I'd like to share mine. The data might be interesting since it indicates acute infection and the period around seroconversion.

Date   Test               Result      Notes
3/01/19   STAT PAK          Negative      
3/01/19   HIV-1 RNA Pool      Negative
3/19/19   STAT PAK          Negative      
3/19/19   HIV-1 RNA Pool      Positive      First positive   
3/19/19   HIV-1 RNA PCR      Positive      1219882 copies/ml
3/25/19   HIV-1 RNA PCR      Positive      2412910 copies/ml
3/27/19   HIV 1/2 Ab Diff positive   Negative      
3/27/19   HIV 1/2 Ab Diff indeterminate   Positive      
3/27/19   HIV 1/2 Ag/Ab combo   Positive      
3/27/19   HIV RNA VL         Positive      2184689 copies/ml
4/10/19   HIV 1/2 Ab Diff positive   Positive      
4/10/19   HIV 1/2 Ag/Ab combo   Positive      
4/10/19    HIV RNA VL          Positive      443 copies/ml

CD4/CD8 Ratio Profile history:

Date   Test               Result
3/25/19   Absolute CD 4 Helper   447
3/25/19   % CD 4 Pos. Lymph.    29.8
3/25/19   Abs. CD 8 Suppressor    750
3/25/19   % CD 8 Pos. Lymph.    50
3/25/19   CD4/CD8 Ratio       0.6
3/27/19   Absolute CD 4 Helper   505
3/27/19   % CD 4 Pos. Lymph.    25
3/27/19   Abs. CD 8 Suppressor    946
3/27/19   % CD 8 Pos. Lymph.    48
3/27/19   CD4/CD8 Ratio       0.53
4/10/19   Absolute CD 4 Helper   516
4/10/19   % CD 4 Pos. Lymph.    25
4/10/19   Abs. CD 8 Suppressor    811
4/10/19   % CD 8 Pos. Lymph.    40
4/10/19   CD4/CD8 Ratio       0.64

Medication history:

3/25/19    Started Biktarvy
4/16/19    Resentfully switched to Triumeq on PCP's order
03-01-2019 HIV- (Stat-Pak & Pooled RNA PCR)
03-17-2019 Symptoms
03-19-2019 Blood draw for test; Stat-Pak negative
03-25-2019 RNA PCR +ve (1219882 copies/ml); Blood draw; Stat-Pak negative; started Biktarvy
03-27-2019 Blood draw for clinical study
04-02-2019 RNA PCR 03-25 (2412910 copies/ml)
04-02-2019 HIV 1/2 Ag/Ab combo: +ve; HIV 1/2 Ab Diff indeterminate; RNA PCR 03-27 (2184689 copies/ml)
04-10-2019 Blood draw for clinical study
04-18-2019 HIV 1/2 Ab Diff: +ve; RNA PCR 04-10 (443 copies/ml)

Offline Jim Allen

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Re: Data sharing: tested positive in March
« Reply #1 on: April 25, 2019, 04:36:10 am »
Hiya

Welcome to the forum, sorry to hear about the diagnosis.
Sounds like you were diagnosed at the end of the window period, despite the diagnosis not being the greatest news the fact you picked it up early and, started treatment is. 

Quote
It's true that I had a hard time during the first week, and later on because all my partners reported to be either on PrEP or undetectable.

This is a familiar story as we here versions of this plenty, not that it matters where you acquired HIV from though and you may never know, what matters is you have let people know to get tested and, that's good so denying it or not they can test & treat themselves.

Time to start looking ahead and focusing on yourself. 

Quote
On the other hand, I've also had immense support from friends, colleagues and family (the select few I revealed my status to).

Glad to hear you have a good support network, a HIV diagnosis can be a lot to initially digest and support really does help.

Quote
3/25/19    Started Biktarvy
4/16/19    Resentfully switched to Triumeq on PCP's order

May I ask why the switch? Was it resistance profile or lab results?

Best, Jim
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline rajagidh

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Re: Data sharing: tested positive in March
« Reply #2 on: April 26, 2019, 12:32:49 am »
Quote
May I ask why the switch? Was it resistance profile or lab results?

The PCP's argument was that Triumeq's shown better results in cohorts with high viral load. I couldn't find evidence for that. A stronger argument might have been that my insurance covered Triumeq but not Biktarvy.
03-01-2019 HIV- (Stat-Pak & Pooled RNA PCR)
03-17-2019 Symptoms
03-19-2019 Blood draw for test; Stat-Pak negative
03-25-2019 RNA PCR +ve (1219882 copies/ml); Blood draw; Stat-Pak negative; started Biktarvy
03-27-2019 Blood draw for clinical study
04-02-2019 RNA PCR 03-25 (2412910 copies/ml)
04-02-2019 HIV 1/2 Ag/Ab combo: +ve; HIV 1/2 Ab Diff indeterminate; RNA PCR 03-27 (2184689 copies/ml)
04-10-2019 Blood draw for clinical study
04-18-2019 HIV 1/2 Ab Diff: +ve; RNA PCR 04-10 (443 copies/ml)

Offline Jim Allen

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  • Posts: 15,816
  • Twitter @JimAllenDublin
    • HIV Lessons
Re: Data sharing: tested positive in March
« Reply #3 on: April 27, 2019, 11:26:10 am »
Hiya

Normally something obvious would stand out as plenty of good drugs are indeed for lower VL counts etc but I did not know or spot anything for Biktarvy in my readings regarding viral load starting limitations, included one ref below.

As for Triumeq i've been taking it for years since it came onto the market in Ireland and had no real issues at all. Swallow its as candy once a day and move on, I do sometimes timings around, such as switch to morning dosing for a while if any sleep issues crop up but that's me.

Best, Jim


https://aidsinfo.nih.gov/drugs/589/biktarvy/203/professional
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

 


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