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Author Topic: HIV Medication Epivir Could Possibly Treat Alzheimer’s  (Read 496 times)

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Offline Jim Allen

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HIV Medication Epivir Could Possibly Treat Alzheimer’s
« on: February 12, 2019, 02:37:18 pm »


Interesting and, any development or insights into fighting Alzheimer’s is good news.

Jim

HIV Medication Epivir Could Possibly Treat Alzheimer’s

Poz.com write-up in full:
https://www.poz.com/article/hiv-medication-epivir-possibly-treat-alzheimers

In Short:

Quote
The study authors treated mice that were 26 months old (about 75 years old in human age) with Epivir and found that even as little as two weeks of therapy reduced signs of the interferon response and inflammation. Six months of treatment in 20-month-old mice had the additional benefit of reducing signs of fat and muscle decline as well as scarring of the kidneys.

The investigators hope to move their research of Epivir into humans to see whether the drug can have an effect on age-related conditions such as frailty, Alzheimer’s disease and arthritis.
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Offline MitchMiller

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Re: HIV Medication Epivir Could Possibly Treat Alzheimer’s
« Reply #1 on: February 13, 2019, 05:15:20 pm »
Lamivudine, a generic HIV/AIDS medication significantly reduces age-related inflammation in old mice by halting retrotransposon activity. Two weeks of treatment reduced the signs of chronic inflammation -- white blood cells stained pink amongst green fat cells -- in old mouse fat tissue.

https://www.sciencedaily.com/releases/2019/02/190206131939.htm

This is the second study of RTI's in Alzheimers; this one from Brown Univ, the other from Sanford Burnham Prebys Medical Discovery Institute.
« Last Edit: February 13, 2019, 05:19:58 pm by MitchMiller »

 


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