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Author Topic: tenofovir effective at lower dose. thai study.  (Read 342 times)

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Offline wardp

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Diagnosed 20,July 2017. Cd4 289, 21% vld .3,462 Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir and viramune due to kidney issues...jan 10,2019 UD.kidney function normal range.

Offline JimDublin

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Re: tenofovir effective at lower dose. thai study.
« Reply #1 on: January 07, 2019, 07:54:47 am »
? ...
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline wardp

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Re: tenofovir effective at lower dose. thai study.
« Reply #2 on: January 07, 2019, 08:14:56 am »
Sorry jim. I just thought that many forum members with tdf kidney issues would like to read this. ?
Diagnosed 20,July 2017. Cd4 289, 21% vld .3,462 Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir and viramune due to kidney issues...jan 10,2019 UD.kidney function normal range.

Offline JimDublin

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Re: tenofovir effective at lower dose. thai study.
« Reply #3 on: January 07, 2019, 08:23:09 am »
 ;D

No need to apologise at all, I was just wondering what the question was. I'll move this to "Research & News Section", I checked and saw a few older and newer studies on this drug and kidney's but not this one yet.

Aidsmap 2015

Quote
Lower daily tenofovir dose of 150mg safe and effective in people with moderate renal impairment

Many people find dosing every 48 hours confusing and inconvenient. Lower strength tenofovir pills (150, 200, 250mg) have recently been approved. Investigators hypothesised that, for adults with moderate renal impairment, treatment with 150mg once daily would provide similar drug exposure to the currently recommended dose of 300mg every 48 hours



The data reported demonstrates that switching TDF to 150mg once daily in HIV-infected adults with moderate renal function impairment leads to comparable exposure to the current recommended 300mg, every 48 hours,” conclude the authors. “This daily dose option for this subpopulation of patients may be preferable to simplify their regimen and facilitate drug adherence but renal function should continue to be closely monitored in these patients
.
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

 


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