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Author Topic: Virus detectives test whole-body scans in search of HIV's hiding places  (Read 1051 times)

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Offline Prince_Bernhard

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This article in Nature is about research on the hiding places of HIV, the so called reservoirs. Identifying the reservoirs might be considered key towards a cure strategy. Patients who were terminally ill and HIV+ provided consent for researchers to check their bodies directly after their death to look for HIV hiding places.

Virus detectives test whole-body scans in search of HIV's hiding places

To prevent the virus from rebounding after drug therapy, researchers must first map where it lurks in the body.

Antiretroviral drugs have transformed HIV infection from a death sentence to a chronic condition for many people who carry the virus. But because HIV never truly leaves the body, the virus rebounds rapidly if patients stop taking the drugs for even a short time.

Now scientists are trying to figure out how, and where, HIV hides when blood tests show that a personís viral load is low or undetectable. The location of this reservoir has long been a mystery, but that could soon change. Powerful new techniques are giving researchers an unprecedented look at how HIV travels though the bodies of people and animals ó turning up clues to the virusís hiding places and new targets for future therapies.


This part is confronting and shows that the virus might be integrated in (nearly) the full body tissue:

The researchers did not detect HIV in the blood of their first donor, who continued taking antiretroviral drugs until his death. But they did find viable virus in nearly all of the 26 tissues they examined after the man died.

I look forward to the results of this study.

Full article: https://www.nature.com/articles/d41586-018-07115-4

Offline Mindless

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Re: Virus detectives test whole-body scans in search of HIV's hiding places
« Reply #1 on: October 22, 2018, 09:40:10 pm »
Thatís interesting, thanks for sharing!


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