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Author Topic: TAF in Thailand?  (Read 1162 times)

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Offline wardp

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TAF in Thailand?
« on: October 11, 2018, 10:36:16 pm »
Hi has anyone got any info on when taf will become available in Thailand?
« Last Edit: October 11, 2018, 10:41:06 pm by wardp »
Diagnosed 20,July 2017. Cd4 289, 21% vld 3000. Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir due to kidney issues.

Offline Gladragsguy

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Re: TAF in Thailand?
« Reply #1 on: October 13, 2018, 04:43:13 am »
TAF is not currently available as a stand alone medication for HIV now anywhere, currently it is used only in single tablet ARVs-DESCOVY, GENVOYA, ODEFSEY, etc...  It seems now likely that it is only better than TDF when it is used with a booster like COBI.  As for coming to Thailand? Now it is looking like December for GENVOYA? Either way GILEAD has proven just how horribly they manipulate the market and patient's hope's with this TDF/TAF nonsense.

Offline wardp

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Re: TAF in Thailand?
« Reply #2 on: October 14, 2018, 10:20:33 pm »
So you  are saying taf is not of any benefit taking with rip viram doutl etc.how many studies have been done to  reach this conclusion.? Is that 1 study?
Diagnosed 20,July 2017. Cd4 289, 21% vld 3000. Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir due to kidney issues.

Offline Mindless

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Re: TAF in Thailand?
« Reply #3 on: October 15, 2018, 09:20:41 am »
Hi Wardp,

I stumbled into this article by chance the other day. It may give you some info in this regard

http://www.aidsmap.com/TAF-only-superior-to-TDF-when-used-with-a-boosting-agent/page/3255399

M

Offline wardp

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Re: TAF in Thailand?
« Reply #4 on: October 15, 2018, 09:01:49 pm »
This study is flawed. It does not prove or disprove long term benefits to renal function.it also seems to be slanting towards cost to UK NHS of taf. I shall post another question?
« Last Edit: October 15, 2018, 09:13:52 pm by wardp »
Diagnosed 20,July 2017. Cd4 289, 21% vld 3000. Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir due to kidney issues.

Offline Gladragsguy

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Re: TAF in Thailand?
« Reply #5 on: October 22, 2018, 06:14:34 am »
Well as it was approved just 2.5 years ago there is not a lot of 'long term' data. It  is only approved as an ARV in 4 combination pills now and only one so far seems to be really coming to Thailand anytime soon (GENVOYA) hopefully mid to late December. This is a patent issue with TAF/TDF so it is not approved as a stand alone med for HIV. So you probably won't be seeing this in anything outside of a GILEAD drug for quite awhile.

Offline Gladragsguy

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Re: TAF in Thailand?
« Reply #6 on: October 22, 2018, 07:36:41 am »
Oh surprise news seems there is a new combo pill with TAF called SYMTUZA approved last month in USA.

Offline wardp

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Re: TAF in Thailand?
« Reply #7 on: October 22, 2018, 11:03:37 pm »
So it is been used without a booster they just haven't done any research on taf with older meds.don't taf and tef work the same way only taf is lower dose. I would imagine taking a lower dose of any meds providing it works can only be a good thing?
Diagnosed 20,July 2017. Cd4 289, 21% vld 3000. Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir due to kidney issues.

Offline Gladragsguy

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Re: TAF in Thailand?
« Reply #8 on: October 24, 2018, 11:13:18 am »
Yes lower dose and slightly different action. But again it is not being used as a stand alone ARV so not really an option outside of the combo pills. We are still waiting for GENVOYA in Thailand.

Offline life2

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Re: TAF in Thailand?
« Reply #9 on: November 01, 2018, 11:09:38 pm »
TAF can be found in India although the online suppliers all feel a bit sketchy.

Offline Expat1

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Re: TAF in Thailand?
« Reply #10 on: November 04, 2018, 09:12:29 am »
Stand alone TAF is sold in India for treatment of HepB.  One name of the medication there is HepBest.  It is also used in combination with other arvs to treat HIV.

Offline Gladragsguy

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Re: TAF in Thailand?
« Reply #11 on: November 07, 2018, 02:36:54 pm »
Again stand alone TAF would be used off label for HIV and do you really want to risk buying your drugs online from India? If everyone is so worried about TAF/TDF why not just go on JULUCA? The best of the best right now, even though the DTG dosage still seems to be overkill.

Offline wardp

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Re: TAF in Thailand?
« Reply #12 on: November 08, 2018, 04:55:30 am »
Everything isn't that simple.if someone wants to buy drugs from India. who are we to judge. We don't all have the luxury off what meds we can have.and some of us must pay for meds etc. If only   one drug combo would  suit all. In a   perfect world.
Diagnosed 20,July 2017. Cd4 289, 21% vld 3000. Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir due to kidney issues.

Offline Expat1

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Re: TAF in Thailand?
« Reply #13 on: November 09, 2018, 05:42:26 am »
Gladragsguy, first you said it wasn't availiable anywhere in the world.  I proved you WRONG. 

No one is suggesting it be the only drug in the combo. 

One can source TAF from India, and get the other nrti/nnrti/ or PI locally here in thailand. 

No Taf combinations are currently availiable in Thailand.

Offline Expat1

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Re: TAF in Thailand?
« Reply #14 on: November 09, 2018, 05:51:39 am »
Juluca is not abailiable in Thailand.

Edurant sourced locally is availiable. 

Tivicay sourced locally is $300 per month.  Or About $55 from India.

Taf is not availiable locally.
Sourced in India it is about $130 for a 3 month supply.
Tafero EM sourced in India is about $50 per month.

Juluca is not an option for someone also infected by HBV.

Did I say I planned to buy online. A round trip air ticket costs about $400 so there are other options. 

And BTY where do you think the world buys most HIV drugs from? (Spoiler alert: INDIA and CHINA).

My Recovir EM is sourced in India. 




Offline Mindless

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Re: TAF in Thailand?
« Reply #15 on: November 10, 2018, 10:02:53 am »
Living in Thailand and being taking Edurant + Recovir, me too I’ve been thinking about the “DIY” version of Juluca, which apparently seems to be a “light” art combination (only 2 drugs). What had made me think is the price of Tivicay here in Los, as Expat says it’s expensive.
Never thought before to India alternative though... this makes me wonder... would it be really an option buying Tivicay there or online? As I said, I’d never given a thought but...

Offline wardp

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Re: TAF in Thailand?
« Reply #16 on: November 11, 2018, 05:40:00 am »
I did fly to India for doultgravir I bought from a recommended source. I'm now on viramune as I had completely lost my appetite on doultgravir and my Dr took me off it.
Diagnosed 20,July 2017. Cd4 289, 21% vld 3000. Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched ricovir em to lamivir due to kidney issues.

Offline Mindless

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  • Posts: 84
Re: TAF in Thailand?
« Reply #17 on: November 11, 2018, 08:45:20 am »
I did fly to India for doultgravir I bought from a recommended source. I'm now on viramune as I had completely lost my appetite on doultgravir and my Dr took me off it.

Thanks Wadp,

I'll PM you for some more info.

M

Offline BKKKevin

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  • Posts: 123
Re: TAF in Thailand?
« Reply #18 on: November 11, 2018, 09:03:27 pm »
Has anyone seen a replacement website link showing what drugs Red Cross has available and pricing in Bangkok?... Adamslove.com used to have a link on thier site with a good list but my understanding is they are no longer affiliated with the Red Cross...

Offline Gladragsguy

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Re: TAF in Thailand?
« Reply #19 on: Yesterday at 10:17:58 am »
I have the current updated price list if you need to know anything you can PM me.

Offline Gladragsguy

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Re: TAF in Thailand?
« Reply #20 on: Yesterday at 10:27:10 am »
Gladragsguy, first you said it wasn't availiable anywhere in the world.  I proved you WRONG. 

No one is suggesting it be the only drug in the combo. 

One can source TAF from India, and get the other nrti/nnrti/ or PI locally here in thailand. 

No Taf combinations are currently availiable in Thailand.
You clearly can not read and do not know what you are talking about. It is not approved as a stand alone medication for HIV treatment. It is only approved as a standalone medication for hepatitis. I have said this several times. So if you do this you will be using it in the way we call off-label which has not been studied. The one pill formulations that are available now have been studied and known to be safe. You clearly have not done your research. The benefits of TAF are still not clear and new studies have shown it might increase cholesterol levels significantly. Obtaining generics overseas always poses risks and a continued reliable supply becomes problematic. What doctor is going to give you this prescription? Oh yes just get it in the corner drugstore in a foreign country.
« Last Edit: Yesterday at 10:29:54 am by Gladragsguy »

Offline JimDublin

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Re: TAF in Thailand?
« Reply #21 on: Yesterday at 01:43:05 pm »
@All

Locked for moment as I'm driving home and ill review later when I'm home.

One thing is for sure debate and opposite views is fine, being bitchy and attacking each other is not!
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline JimDublin

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Re: TAF in Thailand?
« Reply #22 on: Yesterday at 04:34:38 pm »
@OP

As for generic pharmacies and sourcing drugs online, I don't have personal experience with them. I've heard good things, I've heard bad things.  :-\

I do know that without online pharmacies things like PrEP and some treatments in the UK & IRL simply would not have progressed and the Terrence Higgins Trust seems to trust a few of them at least for the PrEP side of the house although I know some of the pharmacies also claim to deliver TAFERO EM https://www.iwantprepnow.co.uk/buy-prep-now/ 

I would however really urge you talk to your doctor first before switching again. You have been through a few combinations and all Ill say is think carefully before switching again. As for TAF, well currently it is not approved as stand-alone, but as we all know "off label" usage of drugs, happens. I'm certainly not recommending it, all i am doing is acknowledging that in the real world it happens.

Work with your doctor, show them the information you find and see what they think.
That's my two cents and whatever you decide to do I wish you the best.

Jim
« Last Edit: Yesterday at 05:16:39 pm by JimDublin »
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline JimDublin

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Re: TAF in Thailand?
« Reply #23 on: Yesterday at 05:13:36 pm »
@Gladragsguy @Expat1

Reason I locked and now unlocked the thread was a mod report and besides that emails sent to me regarding this thread.

Here are the options you have, Ignore each-other or debate each-other however whatever you do remain courteous and polite! There is no need for flame-baiting and personal attacks. There is plenty of that online already without us doing that here, so lets have a slightly better standard and keep things civil.

Ill also add that as forum members we might not always agree with what someone posts, however repeat posting our own point of view simply does not add to the conversation or validate it more.

Anyhow no more personal attacks! 

Thank you for your cooperation.

Jim
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

 


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