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Author Topic: Study findings suggest that STIs increase after participants commence PrEP,  (Read 619 times)

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Offline Jim Allen

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Again do not personally agree with the headline on this one, written below in bold.. Anyhow here it is:

Starting PrEP Is Tied to an Increased Likelihood of Contracting STIs

This finding, from a review of eight studies of 4,400 gay and bi men, suggests this group lowers condom use for anal sex after starting PrEP.

May 29, 2018 By Benjamin Ryan

Beginning Truvada (tenofovir disoproxil fumarate/emtricitabine) as pre-exposure prophylaxis (PrEP) is associated with an increase in the likelihood of being diagnosed with sexually transmitted infections (STIs) among transgender women and cisgender men who have sex with men (MSM). This finding, from a review of multiple studies of PrEP including thousands of participants, suggests that condom use declines in this population during the period immediately following embarking upon a regimen of Truvada for HIV prevention.

Publishing their findings in Clinical Infectious Diseases, researchers conducted a systematic review and meta-analysis of 17 studies on PrEP use among trans women and cisgender MSM published from 2014 to 2017. Eleven of the studies were conducted in the United States and 15 took place in high-income nations.

The studies included 6,671 participants, with a median group of 268 people and a range of 50 to 1,603. The length of follow-up ranged from three to 18 months and was a median six months. The participant age was 34 years, with a range of 18 to 70 years.

Eight studies including 4,388 participants reported data on STI diagnoses at entry into a study and at a follow-up visit. The pooled results indicated that starting PrEP was associated with a 1.24-fold increased risk of an STI diagnosis during follow-up, including a 1.39-fold increased risk of any rectal STI diagnosis and a 1.59-fold increased risk of any rectal chlamydia diagnosis.

Full write-up can be found here: https://www.poz.com/article/starting-prep-tied-increased-likelihood-contracting-stis
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