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Author Topic: HIV Medications  (Read 5889 times)

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Offline Jim Allen

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HIV Medications
« on: March 08, 2018, 07:24:18 am »
*** Note: Updated post included further down this thread with 2018 details and drug charts***

We’ve come a long way since the early years of the HIV/AIDS epidemic. Today, there are safe and effective drugs on the market to treat HIV that are easy to take and have fewer side effects.

Click for a list of approved and experimental HIV medications

Click for a list of approved HIV medications and their dosing info.

Click for a printable version of the POZ 2017 Drug Chart. (updated July 2017

For information about the specific classes of HIV drugs, links can be found here: hiv-medications
Single-Tablet Regimens
Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Protease Inhibitors (PIs)
Integrase Inhibitors
Monoclonal Antibodies
Entry Inhibitors
Pharmacokinetic Enhancers



Anyone looking for information on starting treatment can begin by reading this brief and useful lesson: Starting treatment.

Click for treatment recommendations.
« Last Edit: June 26, 2018, 04:50:24 am by JimDublin »
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
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You can read about HIV prevention here:
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PEP and PrEP

Offline wardp

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Re: HIV Medications
« Reply #1 on: March 08, 2018, 09:22:18 pm »
Thanks Jim, but still a problem with the generics of all these new drugs been made available in all asian countries including Thailand,i hope they become available at affordable cost to all soon,  indian companies such as mylan and hetero  cipla etc are leading the way in generic arvs,
Diagnosed 20,July 2017. Cd4 289, 21% vld .3,462 Started atripla 4 Aug 2017 5oct 2017 cd4 384 21%, vl ud less than 20. Switch to complera 4 Nov 2017 switched to stribild 15 the Nov. Switched to truvada efavirence 200mgx2 14 Dec 2017, 2 Feb 2018, us cd4  466, 25%  CD 8 ,595, 32%..1 may 2018
switched  to instgra truvada.7th june switched to truvada  nevirapine stavudine. .21 june switched to truvada nevirapine. X 2 a day...9 aug 2018 ud. 2n Nov 2018 CD 4. 455..22.70% 13th Nov switched  to lamivir and nevirapine  due to kidney issues...jan 10,2019 UD..may 13 2019 ud  cd4 482 28% 14th nov 2019 ud. Cd4 414 .27% cd8 444 29%,may 16 2020,ud ,cd4 741"19.62.

Offline Jim Allen

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Re: HIV Medications
« Reply #2 on: March 09, 2018, 02:17:38 am »
Generics take time, but its good to know what treatment combination are possible and out there. ;) Unfortunately i doubt ill ever have an (up-to-date) guide for every individual nation.
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline kentfrat1783

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Re: HIV Medications
« Reply #3 on: April 14, 2018, 09:20:09 am »
I've actually looked into the generics through my insurance and the co-pays I'd have to pay are higher then the brand name Rx.  That part is shocking but when they came to talk to us at work they said sometimes that will be true as they feel the brand name Rx is better. 

06/08/2020 - CD4 257 (20%) VL <20
03/17/2020 - CD4 285 (19%) VL 101       (2.00)
09/17/2019 - CD4 218 (16%) VL (?)
06/18/2019 - CD4 173 (16%) VL <20
03/13/2019 - CD4 170 (16%) VL <20
January 2019 - Started Triumeq
12/05/2108 - CD4 174 (18%) VL <20
08/28/2018 - CD4 166 (15%) VL <20
05/08/2018 - CD4 106 (11%) VL <20
03/05/2018 - CD4   90 (10%) VL <20
12/11/2017 - CD4   60 (  8%) VL ?
09/07/2017 - CD4   42 (  6%) VL  54        (1.70)
May 2017 - Started Atripla
05/11/2017 - CD4     2 (  1%) VL 169,969 (5.23)
OI's: PCP
Dx`d May 11, 2017
Location: USA

Offline Jim Allen

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Re: HIV Medications 2018
« Reply #4 on: June 26, 2018, 03:30:30 am »
Updated with 2018 details and drug charts.

We’ve come a long way since the early years of the HIV/AIDS epidemic. Today, there are safe and effective drugs on the market to treat HIV that are easy to take and have fewer side effects.

Click for a list of approved and experimental HIV medications

Click for a list of approved HIV medications and their dosing info.

Click for a printable version of the POZ 2017 Drug Chart. (updated July 2017

For information about the specific classes of HIV drugs, links can be found here: hiv-medications

Single-Tablet Regimens
Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Protease Inhibitors (PIs)
Integrase Inhibitors
Monoclonal Antibodies
Entry Inhibitors
Pharmacokinetic Enhancers



Anyone looking for information on starting treatment can begin by reading this brief and useful lesson: Starting treatment.

Click for treatment recommendations.
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline bufguy

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  • Posts: 214
Re: HIV Medications
« Reply #5 on: December 23, 2018, 12:07:43 pm »
Thanks for providing such great info. I recently had my six month check up and my doc had been suggesting I might want to replace my Atripla with a new regimen. Using this website as a resource I spent a lot of time researching. I printed out your chart, looked at the pros/cons of each med, and even brought the chart with me to my doc. She was impressed at my knowledge on all that is available. Long story short, I decided to switch  to Biktarvy
5/29/08 confirmed HIV+
6/23/08 Vl 47500  CD4 511/29% CD8 .60
start atripla
8/1/08 Vl 130  CD4 667/31% CD8 .70
9/18/08 Vl un  CD4 not tested
12/19/08 Vl un CD4 723/32% CD8 .80
4/3/09 Vl un CD4 615/36% CD8  .98
8/7/09 vl un CD4 689/35% CD8 .9
12/11/09 vl un CD4 712/38% CD8 .89
4/9/10 vl un CD4 796/39% CD8 1.0
8/20/10 vl un CD4 787/38% CD8 1.0
4/6/10 vl un CD4 865/35% CD8 .9
8/16/10 vl un CD4 924/37% CD8 1.0
12/23/10 vl un CD4 1006/35% CD8 .9
5/2/10 vl un CD4 1040/39% CD8 .9
8/7/13 vl un CD4 840/39% CD8 .
11/29/18 vl un CD4 1080/39% CD8  .86

Offline Jim Allen

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Re: HIV Medications
« Reply #6 on: December 24, 2018, 12:48:50 pm »
Glad the chart helped and, ill pass on the feedback.

Biktarvy - cool, hearing a lot of good things about this combo.
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline Jim Allen

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    • HIV Lessons
Re: HIV Medications 2019
« Reply #7 on: July 29, 2019, 11:14:33 pm »
Updated with new links to the updated drug charts, 1st of July 2019.

We’ve come a long way since the early years of the HIV/AIDS epidemic. Today, there are safe and effective drugs on the market to treat HIV that are easy to take and have fewer side effects.

https://www.poz.com/article/2019-hiv-drug-chart

Click for a list of approved and experimental HIV medications

Click for a list of approved HIV medications and their dosing info.

Click for a printable version of the POZ 2019 Drug Chart. (updated July 2019)

For information about the specific classes of HIV drugs, links can be found here: hiv-medications

Single-Tablet Regimens
Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Protease Inhibitors (PIs)
Integrase Inhibitors
Monoclonal Antibodies
Entry Inhibitors
Pharmacokinetic Enhancers



Anyone looking for information on starting treatment can begin by reading this brief and useful lesson: Starting treatment.

Click for treatment recommendations.
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline Jim Allen

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Re: HIV Medications
« Reply #8 on: December 22, 2019, 02:40:16 am »
December 2019

US - Updated treatment guidelines
https://www.poz.com/article/us-government-updates-hiv-treatment-guidelines

An overview of what has changed/been updated
https://www.poz.com/article/us-government-updates-hiv-treatment-guidelines

In short:
Quote
Treatment as Prevention

The new guidelines reflect the growing understanding that people on effective antiretroviral treatment who have an undetectable viral load (under 200) do not transmit the virus to their sex partners.  The panel recommends that people starting treatment should use another form of prevention—for example, condoms or PrEP for a partner—for at least the first six months and until they receive an undetectable viral load test result.

First Two-Drug Initial Regimen

Dovato - For the first time, the guidelines include a two-drug combination to the list of recommended regimens for starting treatment; such recommendations were previously limited to three-drug regimens.  The other approved two-drug single-tablet regimen, Juluca (dolutegravir/rilpivirine), is only for people who switch treatment with an undetectable viral load, not for initial therapy.

Rapid Treatment Initiation

The guidelines recommend that antiretroviral therapy should be started immediately or as soon as possible after HIV diagnosis.  For those with acute or recent infection, the panel added Biktarvy (bictegravir/tenofovir alafenamide/emtricitabine) as a recommended option for those who will start treatment before resistance test results are available.

Cost Considerations

The guidelines have an updated section on cost considerations related to antiretroviral treatment, including an overview of the individual and societal costs of HIV care in the United States. A new subsection on cost sharing looks at how cost-containment practices may affect out-of-pocket payments for people with Medicaid, Medicare and AIDS Drug Assistance Program (ADAP) coverage. The section also features a revised discussion about the increased cost of brand-name antiretrovirals and the expected impact of generic regimens as these drugs go off patent.

Tuberculosis

The tuberculosis section has been updated with new data on short-course regimens for the treatment of latent tuberculosis and new data on drug interactions between antiretrovirals and the TB drugs rifampin and rifapentine.
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline fabio

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  • Posts: 561
Re: HIV Medications
« Reply #9 on: December 22, 2019, 05:14:42 am »
The names are quite funny haha. Dovato is a fusion of Demy Lovato........
I also noticed most of the meds revolve around tenofovir and emtricirabine.

 


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