Welcome, Guest. Please login or register.
November 19, 2019, 06:14:37 am

Login with username, password and session length


Members
Stats
  • Total Posts: 749304
  • Total Topics: 62910
  • Online Today: 415
  • Online Ever: 4912
  • (November 13, 2019, 02:56:14 am)
Users Online
Users: 0
Guests: 381
Total: 381

Welcome


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: New meds - Biktarvy and GI side effects  (Read 3022 times)

0 Members and 1 Guest are viewing this topic.

Offline contagion

  • Member
  • Posts: 88
New meds - Biktarvy and GI side effects
« on: September 14, 2017, 11:26:25 pm »
I feel like I ever only post about gas here. I've been suffering from extreme gas for few years now and I'm on Triumeq. I also suffer from reflux which is getting worse and I feel like I have sore throat all the time. I've tried dietary changes and it doesn't seem to help much. I've been to a few doctors who don't seem to know how to handle GI side-effects. I see there are now new options like - Genvoya, Odefsey and Descovy. Does anyone know the GI side-effects for these new regimens? The last time I asked my doctor, which was probably a year back - he basically told me this is as good as it gets and to live with my daily suffering.
I have a t-shirt with my t-cells on it.

Offline contagion

  • Member
  • Posts: 88
Re: New meds - Biktarvy and GI side effects
« Reply #1 on: June 24, 2018, 11:27:15 pm »
My doctor recently told me about two new pills Biktarvy and Juluca. Biktarvy is quite a small pill and has no booster.
I'm currently on Triumeq and suffer bad GI symptoms from it..mainly bloating and gas -the kind that actually stops you from having a normal life. I don't mind taking two pills or old pills if it means it will help stop the abnormal gas. Does anyone know what kind of pills would have less effect on the GI system? I'm considering Biktarvy as the components have a smaller dosage..so maybe it will help. 
I have a t-shirt with my t-cells on it.

Offline Jim Allen

  • Administrator
  • Member
  • Posts: 13,639
  • Twitter @JimAllenDublin
    • HIV Lessons
Re: New meds - Biktarvy and GI side effects
« Reply #2 on: June 25, 2018, 02:31:37 am »
https://forums.poz.com/index.php?topic=53799

https://forums.poz.com/index.php?topic=55480

I see its an ongoing issue for you with previous combo's as well, sorry to read that back.  Juluca is dolutegravir and rilpivirine, so its means you would be sticking to the dolutegravir line. 

Biktarvy is bictegravir, emtricitabine, and tenofovir alafenamide. So its contains TAF the newer TDF but reading back I see you dropped TDF a while back and although TAF is a much smaller dosage if TDF did cause issues before I would personally be hesitant

Jim 
HIV 101 - Everything you need to know
HIV 101
Transmission and Risks:
HIV Transmission and Risks
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

Offline Mightysure

  • Member
  • Posts: 422
Re: New meds - Biktarvy and GI side effects
« Reply #3 on: June 25, 2018, 10:47:41 am »
There may be something to this because my friend is on Ttiumeq and he has the worst gas I've ever seen (well, heard). He always attributes it to whatever he has eaten or drank, but water doesn't typically cause gas to that extreme.
I can say that being on Tivicay by itself causes no gi issues. And now on rilpivirine doesnt either so Juluca may be something worth trying.

Offline contagion

  • Member
  • Posts: 88
Re: New meds - Biktarvy and GI side effects
« Reply #4 on: June 25, 2018, 11:25:26 pm »
@Mightysure thank you for your patience. Yes I've been having this issue for years. I started with Atripla...and it's been downhill since then.  So this is what I gather -

Stribild - Was worst on this. Has Tenofovir, that's known to cause gas
Triumeq - No Tenofovir, but still bad enough
Biktarvy - Has newer Tenofovir, smaller dose, don't know if it causes gas
Juluca - Has dolutegravir, same as triumeq

@Mightsure Thank you for your input. Definitely helps to know other people experience similar side effects.  I think Juluca might be worth a try, but I'm pretty unsure about the whole 2 meds thing. Found an interesting article about the future of hiv therapy.

If anyone has an opinion in helping me choose a new med, would be much appreciated.  :)
I have a t-shirt with my t-cells on it.

Offline Mightysure

  • Member
  • Posts: 422
Re: New meds - Biktarvy and GI side effects
« Reply #5 on: June 26, 2018, 12:17:41 pm »
No problem.  Im a science nerd so I have a keen interest in pharmacology. 
My laymans guess is that NRTI, such as Tenofovir, Abacavir, and Lamuvidine may be the culprits because if you notice, you've always had a regimen with a NRTI. When I first started Stribild and took Truvada, I did notice intestinal issues that eventually went away. 
I've had experience with Tivicay and Tenofovir and Emtricitabine and I dont think it's the integrase inhibitors.


Im in a clincial trial for a two drug regimen and it works great.  I haven't had any noticable side effects, numbers are good, and as I mentioned in my thread, I'm sleeping better and my digestive system is functioning better. And it's the first time Im not taking a NRTI.

I say give Juluca a fair shot.

Offline contagion

  • Member
  • Posts: 88
Re: New meds - Biktarvy and GI side effects
« Reply #6 on: June 26, 2018, 09:52:49 pm »
That was very helpful @Mightysure
I will keep this thread updated on any progress...in case it helps others with similar issues!
I have a t-shirt with my t-cells on it.

Offline spiritualhgangster

  • Member
  • Posts: 3
Re: New meds - Biktarvy and GI side effects
« Reply #7 on: February 02, 2019, 11:14:17 pm »

Any luck finding a cure for this annoying side affect?

Offline Brad711

  • Member
  • Posts: 10
Re: New meds - Biktarvy and GI side effects
« Reply #8 on: February 03, 2019, 04:02:50 pm »
i'm going on my 2nd week of Juluca after I switching over from Atripla. So far I've had no issues at all. I'll be anxious in 3 months to see my test results to see how its going. Overall thou, i've had no side effects from Juluca.  Only minor complaint is I liked to before take my vitamins in the morning before work and since I take Juluca now in the morning with my breakfast you have to wait 4 hours before taking vitamins with Iron and Calcium. So i pop those now at lunch time.

Offline kentfrat1783

  • Member
  • Posts: 276
Re: New meds - Biktarvy and GI side effects
« Reply #9 on: February 03, 2019, 07:43:13 pm »
Hi,

This is an interesting thread to read.  I just started on Triumeq 7 days ago and I have noticed excess air in my stomach that has caused a ton of belching.  Not much gas out of the other end but that has also been increasing. 

I have an appointment in a month with my specialist to see if the new Rx is working and I'm going to be asking if this is an odd side effect or so what is going on. 

On on a positive note, I've been sleeping a lot better.  I'm just glad I'm off Atripla.  Let's just hope Triumeq is doing its job.

Thanks,
Kenneth
09/17/2019 - CD4 218 (16%) VL (?)
06/18/2019 - CD4 173 (16%) VL <20
03/13/2019 - CD4 170 (16%) VL <20
January 2019 - Started Triumeq
12/05/2108 - CD4 174 (18%) VL <20
08/28/2018 - CD4 166 (15%) VL <20
05/08/2018 - CD4 106 (11%) VL <20
03/05/2018 - CD4   90 (10%) VL <20
12/11/2017 - CD4   60 (  8%) VL ?
09/07/2017 - CD4   42 (  6%) VL  54        (1.70)
May 2017 - Started Atripla
05/11/2017 - CD4     2 (  1%) VL 169,969 (5.23)
OI's: PCP
Dx`d May 11, 2017
Location: USA

 


Terms of Membership for these forums
 

© 2019 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.