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Author Topic: Switching from Complera  (Read 1659 times)

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Offline completelypozitive

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Switching from Complera
« on: June 27, 2014, 03:47:11 PM »
I was diagnosed 2 years ago. I started my first regimen in April 2014. I was informed at my appointment today (June 27) that I was resistant to one of the components of Complera and would need to stop taking it, although my CD4 dramatically increased in less than 3 months.

I was given little information regarding any new regimen, other than the choices of taking Prezista or Reyataz (in combination with the other two components in Complera).

I am also allergic to Bactrim and very confused as to whether or not I can take either drug. I also wanted anyone's experience coming off Complera...any side effects, what to expect, etc?

Offline gadawg1979

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Re: Switching from Complera
« Reply #1 on: June 28, 2014, 01:47:28 AM »
Odd to take you off if your numbers are going up....
Diagnosed March 2012
Initial CD4- 156 VL 200K (started Complera) Genotype test no resistance
First labs on meds CD4- 246 VL 2K Taken after 30 days on Complera
90 Day labs VL 306 No CD4 Drawn
8/21/2012 CD4 474 VL Undetectable (40) %20.6
11/27/2012 CD 4 522 VL Undetectable (40)
2/14/2013 CD 4 464 VL Undetecable (30) 19.6%
6/8/3013 CD 4 528 VL Undetectable (30)
9/24/2013 CD 4 546 VL Undetectable (40)
1/30/2014 CD4 560 VL Undetectable (40) 22 %
6/19/2014 CD4 584 Vl Undetecable (30)

Offline completelypozitive

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Re: Switching from Complera
« Reply #2 on: June 28, 2014, 02:27:52 PM »
I know my numbers are going up, but they said I was resistant to Edurant. So I assume that those numbers will eventually change and not for the better. I have a doctor's appointment Tuesday, but I wanted to get as much information before starting a new regimen. The first was bad enough and now I have to go through all this again 3 months later.

Offline Jeff G

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  • How am I doing Beren ?
Re: Switching from Complera
« Reply #3 on: June 28, 2014, 02:39:12 PM »
Welcome to the forums ! . I understand that this feels like a set back but it really isn't . 
There are many other combo treatments to go to to keep you healthy for a lifetime so this is just a bump in the road .

I have been through a few combos myself over the years and have been poz for at least 30 years or more . I am not special so if I can do this you can too . Chin up ... you are going to be OK . 
HIV 101 - Basics
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Offline eric48

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Re: Switching from Complera
« Reply #4 on: June 29, 2014, 05:09:37 AM »
I was diagnosed 2 years ago. I started my first regimen in April 2014.

US and EU guidelines require that a resistance test be done prior starting meds. Do you know if that has been done? Eric

BTW, Welcome here...
NVP/ABC/3TC/... UD ; CD4 > 900; CD4/CD8 ~ 1.5   stock : 6 months (2013: FOTO= 5d. ON 2d. OFF ; 2014: Clin. Trial NCT02157311 = 4days ON, 3days OFF ; 2015: https://clinicaltrials.gov/ct2/show/NCT02157311 ; 2016: use of granted patent US9101633, 3 days ON, 4days OFF; 2017: added TDF, so NVP/TDF/ABC/3TC, once weekly

Offline completelypozitive

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Re: Switching from Complera
« Reply #5 on: June 29, 2014, 11:50:58 AM »
Thank you Jeff for the kind words. Eric (thank you for the welcome)...I had the genotype test, if that is what you are referring to, but if there is a specific "resistance" test...I am not sure if that was given.

I am told that I have the best doctor here, that specializes in infectious disease. I would not neccessarily agree with that, but I have trusted them so far (other than my own research online). I would hope that she would have wanted to know if I was resistant to any component of Complera before I took it. I will most certainly ask when I see her in a couple days.


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