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Author Topic: Switching to complera or Truvada + isentress  (Read 1591 times)

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Offline hivtalian

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  • Posts: 57
Switching to complera or Truvada + isentress
« on: May 03, 2014, 10:53:37 AM »
Hi all,
I'm in a bit of doubtful period because my doc is gonna change my drugs, wich I started in the acute phase as a study procol as Truvada+Isentress+Prezista+Norvir.

After 4 months I'm at 59 VL and 901 CD4 starting from >500000 and at about 700 CD4.

I noticed some thinning of my cheeks and was feared of lipo, but she told me it's very rare after just 4 months, but anyway she is gonnna change my drugs because the whole stuff was made because of a very early start in the acute phase and now that my numbers are good she can lower the pills.

She proposed to switch to Eviplera (COmplera) or to stop Prezista and Norvir leaving only Truvada and Isentress.

What do you think in your experience? She said she maybe would prefere complera because she wants to "save" integrase inhibitors for later before I get any resistance, but I read that complera is not indicated if early VL was veri high...

Has anyone experience on this? what do you think I should do?

Thank you for any suggestions!

Offline vertigo

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Re: Switching to complera or Truvada + isentress
« Reply #1 on: May 03, 2014, 01:38:50 PM »
As long as you're OK with twice-a-day treatment, why not just stick with the Isentress/Truvada?  The fact that you're already on it makes this a very simple course of action.  I'm not sure what the point of "saving" the integrase inhibitor class for later is ... just be sure to be adherent when taking your meds and you should not have resistance issues.  Also, technically, since you're already on Isentress you've already "used" this class of meds and are no longer considered integrase inhibitor-naive.

If you did want to switch to Complera there wouldn't be a problem with doing so.  It's not a recommended drug if your viral load is over 100K, but yours is nearly undetectable.  Your initial viral load is irrelevant at this point.  But be aware that Complera does have a meal requirement, which your current meds do not.  Still, most people find it an easy drug to take, and it has the convenience of being just one pill a day.
« Last Edit: May 03, 2014, 01:41:15 PM by vertigo »

Offline hivtalian

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  • Posts: 57
Re: Switching to complera or Truvada + isentress
« Reply #2 on: May 03, 2014, 05:47:40 PM »
Thx vertigo, really very kind:)
I'll keep you posted on what she/I'll decide...
kind of anxiety now that I was pretty in a good equilibrium with my drugs, but I know it's to make things easier and better for me...

Offline hivtalian

  • Member
  • Posts: 57
Re: Switching to complera or Truvada + isentress
« Reply #3 on: May 05, 2014, 12:30:58 PM »
Done it!
Switched to truvada and isentress .
Hopefully a good choice! Thank you again!


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