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Author Topic: Isentress/ raltegravir  (Read 2466 times)

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Offline Susan

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  • Posts: 9
Isentress/ raltegravir
« on: July 26, 2013, 04:22:01 PM »
I started Isentress about one month ago. I am experiencing muscle cramps in my calves and was wondering if anyone else experienced this and if it lessened with time?

Offline ad2san

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  • Posts: 235
Re: Isentress/ raltegravir
« Reply #1 on: July 26, 2013, 05:43:41 PM »
I don't  8)
Feb   2009 CD4 358 VL 2000 16%
May  2009 CD4 305 VL 3069  14% <---- Started TVD+ATZ/r
Jul  2009 CD4 512 VL <50   18%
Jul 2010 CD4 418 VL <50 24%                     
Switched to Kivexa (Epzicom) + Norvir + Reyataz (due to sleep problem)
Aug 2010 CD4 606 VL <50 25%
Jul 2011 CD4 494 UD 23%
Switched to Kivexa (Epzicom) + Viramune XR (due to kidney problems)
January 2012 CD4 564 UD 31%
January 2013 CD4 594 UD 26%
Switched to Kivexa (Epzicom) + Isentress due to BIG increase GammaGT
Feb 2013 CD4 699 UD 28%
Aug 2014 CD4 639 UD 25%
Switched January 2015 to Triumeq
May 2015 CD4 807 UD 31%
Switched Nov 2016 to Genvoya due to gastric problems
November 2016 CD4 847 UD 32%

Offline a2z

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  • Posts: 208
Re: Isentress/ raltegravir
« Reply #2 on: July 30, 2013, 06:02:56 AM »
I have but to be fair I had them Pre-Isentress too.  I drink coconut water to help with them.
Dates are blood draw dates:
3/12/15: CD4 941, 36.4%, VL UD
9/4/14: CD4 948, 37.9%, VL 150
5/23/14: CD4 895 --.-% VL UD - Truvada/Isentress
09/21/09: CD4 898 27.0% VL 120 - back on track, same meds.High level enzymes, but less so
06/15/09: CD4 478 21.8% VL 1150 - high liver enzymes... looks like I may not be resistant
05/22/09: Fixed insurance, resumed medicine
04/17/09: Ran out of medicine, could not resolve insurance problems
04/01/09: CD4 773 28% VL 120 - high liver enzymes
12/01/08: CD4 514 23% VL 630
10/17/08 started Reyataz, Norvir and Truvada. -- possibly minor neuropathy, but otherwise okay.
9/10/08: CD4 345 17%, VL > 78K
8/18/08: CD4 312 18%, VL > 60K (considering meds)
12/19/07: CD4 550 28% VL > 100K (no meds yet)
Diagnosed 10/23/07

Offline Ann

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  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Isentress/ raltegravir
« Reply #3 on: July 30, 2013, 10:25:34 AM »
Sometimes leg cramps are associated with low potassium levels. Eating bananas often takes care of it (one or two a day, for example). If you start eating bananas and don't see an improvement, take it up with your doctor.
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Offline eric48

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Re: Isentress/ raltegravir
« Reply #4 on: July 30, 2013, 05:44:19 PM »
My lab test Rx always bear :

perform CPK dosage in case of muscle pain

I have this because I take Crestor (rovustatin) for lowering LDL and I take praxil for depression (although, I think I should be able to put this behind me sometime this year)

All those medications we take are 'inhibitors' and muscle pain is a common side effect (5% in case of Rovustatin)

I have Muscle twitching 24H/days, 7 days/week for now 3 years. It is not painfull but odd... It appeared 2 months after initiating the meds...

cramps can be due to elevated urea in blood: more water intake might help too

Hope this helps

NVP/ABC/3TC/... UD ; CD4 > 900; CD4/CD8 ~ 1.5   stock : 6 months (2013: FOTO= 5d. ON 2d. OFF ; 2014: Clin. Trial NCT02157311 = 4days ON, 3days OFF ; 2015: https://clinicaltrials.gov/ct2/show/NCT02157311 ; 2016: use of granted patent US9101633, 3 days ON, 4days OFF; 2017: added TDF, so NVP/TDF/ABC/3TC, once weekly

Offline lincoln6echo

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  • Posts: 110
Re: Isentress/ raltegravir
« Reply #5 on: July 31, 2013, 02:21:08 AM »
hmmm funny you bring this up.

I just switched to this regimen about two mo's ago and I've recently been having cramps in my right calf muscle...

i'll inquire and see what he says at my appt this week and report back.

Offline Shayne504

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  • Posts: 33
Re: Isentress/ raltegravir
« Reply #6 on: July 31, 2013, 10:26:15 AM »
I started Isentress about 10 days ago, and had cramps in my calves as well. But I've had muscle cramps at night for years. They stopped after a couple of days.

Be fore I started treatment I had gone on a weight loss program cutting out all soft drinks and fast food. I lost about 17#'s in 6 weeks and wanted to start exercising to add to it but my Dr said not yet so if I did have complications he would know if it was the Isentress.

I know it sounds crazy but I was like a kid at Christmas when I got my meds. I felt like I was finally taking another step to getting better.

Tested Poz 04/10/13
05/23/13 CD4-109 VL 104K
06/16/13 CD4-80 VL 89K


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