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Author Topic: So in a perfect world , what drugs if you had to be on them would you choose...  (Read 3052 times)

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Offline surf18

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  • Posts: 532
that were the least likely to cause side effects? belly discomfort? all forms of lipo?

Offline leatherman

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  • Google and HIV meds are Your Friends
since the chances for most short-term medication side effects are under 10% (those are the general ones like nausea etc while one's VL decreases and immune system recovers) and most long-term medication side effects chances are under 3% (like lipo), I'd simply go with any of the first line regimens available in my area.

(It's probably important to note here that with restricted access to HIV treatment, many people can only "afford" to take what is available, and really don't have much in the way of "choice". Even insurance companies often have only certain meds on their formulary, so the real available selection of med is often diminished limiting the patient's "choice")

Of course sometimes meds act differently for different people, so you always take a chance that the outcome will be good not bad. Aspirin kills people daily, yet most people don't think twice about popping one or two to stop a headache (disclaimer: I'm very allergic to aspirin and nearly died twice before figuring out that it was the aspirin). Thankfully, with HIV meds in 2012, unlike in 1992 with only AZT, there are so many options. If something doesn't work well for a person there is always something else to switch to, or usually something to do to deal with the side effect. Sadly no one can predict the future, so there's just no way to know what long term effects await anyone on any regimen.

quite frankly I'm much more of an optimist (even with the AIDS, deaths of partners, house fire, car wrecks, times of near homelessness and poverty that I've gone though). I never imagine myself as the one who WILL experience side effects. Instead I like to take the odds and believe that I'm in the 90+% who won't experience anything but improved health  ;D
leatherman (aka mIkIE)

All the stars are flashing high above the sea
and the party is on fire around you and me
We're gonna burn this disco down before the morning comes
- Pet Shop Boys

chart from 1992-2015

Offline denb45

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  • Posts: 5,053
  • "1987 Classic Old School POZ+"
In a perfect world, I wouldn't be on any AVR-Meds cause I wouldn't have teh AIDS  ;)
"it's so nice to be insane, cause no-one ask you to explain" Helen Reddy cc 1974

Offline Common_ground

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  • Posts: 292
Most important for me in a combo:
* As little damage as possible to organs and the body.
* Durability and effective against my strain of HIV.
* Studied extensively.

What doesnt bother me:
* Number of pills - I dont have a problem with many pills or 2 times a day dosing.
* Forgiving on dosing time - I dont miss doses and are always within 1 hour.
* Side effects which are more of an annoyance, but not making any physical long lasting harm.

Right now Im on Truvada and Stocrin. Im not sure if this combo matches my outline.?.

Somehow I have turned against going on Isentress, Complera and newer meds because I fear that If I fail a new regimen I might have to "go back" to an older drug which isnt as easy on my body and It will complicate my resistance profile more than failing a somewhat older regimen. It might not make sense but thats how I feel. :o

2011 May - Neg.
2012 June CD4:205, 16% VL:2676 Start Truvada/Stocrin
2012 July  CD4:234, 18% VL:88
2012 Sep  CD4:238, 17% VL:UD
2013 Feb  CD4:257, 24% VL:UD -viramune/truvada
2013 May CD4:276, 26% VL:UD

2015 CD4: 240 , 28% VL:UD - Triumeq
2015 March CD4: 350 VL: UD

Offline Billy B

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  • Posts: 385
The two that I am on.
VL 4420 CD4 340 CD4% 24   3/15/10 Started I&T
VL  UD   CD4 340 CD4% 26.5 05/13/10
VL  UD   CD4 360 CD4% 27.1 08/3/10
VL  UD   CD4 310 CD4% 28.4 11/22/10
VL  UD   CD4 420 CD4% 27.9 02/11/11
VL  UD   CD4 370 CD4% 26.4 06/08/11
VL  UD   CD4 360 CD4% 27.7 09/23/11
VL  UD   CD4 370 CD4% 28.3 01/20/12
VL  UD   CD4 430 CD4% 28.8 05/11/12
VL  UD   CD4 370 CD4% 28.1 09/07/12
VL  UD   CD4 390 CD4% 32.3 03/14/13
VL  UD   CD4 450 CD4% 29.8 09/10/13
VL  UD   CD4 430 CD4% 31.0 04/29/14
VL  UD   CD4 520 CD4% 34.8 11/05/15
VL  UD   CD4 440 CD4% 33.5 03/10/15
VL  UD   CD4 450 CD4% 30.5 08/23/16

Offline buginme2

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  • Posts: 3,426
Perfect world!

1.  Obviously I would go with an option thate cured the HIV (perfect world and all)

2.  Otherwise I would go with gs-7340 (not out yet) because it has efficency of Tenofovir at a much lower concentration.  That combined with maybe Dolutegravir (because its a once a day option that doesnt need boosting) and another NRTI.  Preferably all combined in one easy pill!

3.  Otherwise I will stick with my Atripla.  I am fortunate to not have any side effects from it and I like the once a day, one pill convenience.
Don't be fancy, just get dancey

Offline leatherman

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  • Google and HIV meds are Your Friends
In a perfect world, I wouldn't be on any AVR-Meds cause I wouldn't have teh AIDS  ;)
leatherman (aka mIkIE)

All the stars are flashing high above the sea
and the party is on fire around you and me
We're gonna burn this disco down before the morning comes
- Pet Shop Boys

chart from 1992-2015

Offline thunter34

  • Member
  • Posts: 7,361
  • His name is Carl.
X, K and G...though I suppose you mean HIV drugs, don't you?

In that case, the ones that I am on are fine (Prezista, Truvanda + Norvir). 
AIDS isn't for sissies.

Offline surf18

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  • Posts: 532
Thanks guys! Good posts!

Offline zach

  • Member
  • Posts: 3,423
in a perfect world, huge bags a marijuana always at ready, 5 grams of dmt per week, and i ain't got teh aids, its a perfect world

atripla for the less than perfect world
I set into a downward spiral
Caught an illness that was literally viral
I heard some words of wisdom the other day
And they went in one ear and out the other one

I awoke from this beatific binge
With prismatic eyes, now lite is tinged
With all the vapors that the vile humans brew
Shining through the blight of you

Offline bufguy

  • Member
  • Posts: 189
I would continue on Atripla. Four years now, no side effects, consistently undetectable, CD4 1200, once per day dosing and although I have been 100% adherent, Atripla is very forgiving as far as dosing.
In my opinion still the gold standard.
5/29/08 confirmed HIV+
6/23/08 Vl 47500  CD4 511/29% CD8 .60
start atripla
8/1/08 Vl 130  CD4 667/31% CD8 .70
9/18/08 Vl un  CD4 not tested
12/19/08 Vl un CD4 723/32% CD8 .80
4/3/09 Vl un CD4 615/36% CD8  .98
8/7/09 vl un CD4 689/35% CD8 .9
12/11/09 vl un CD4 712/38% CD8 .89
4/9/10 vl un CD4 796/39% CD8 1.0
8/20/10 vl un CD4 787/38% CD8 1.0
4/6/10 vl un CD4 865/35% CD8 .9
8/16/10 vl un CD4 924/37% CD8 1.0
12/23/10 vl un CD4 1006/35% CD8 .9
5/2/10 vl un CD4 1040/39% CD8 .9
8/7/13 vl un CD4 840/39% CD8 .9


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