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Author Topic: Consumption Of Probiotics Associated With Reduced Risk Of Diarrhea From Antibiot  (Read 3337 times)

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Offline J.R.E.

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  • Joined Dec-2003 Living positive, since 1985.

Main Category: GastroIntestinal / Gastroenterology
Also Included In: Nutrition / Diet
Article Date: 09 May 2012 - 10:00 PDT

Consuming probiotics reduces the risk of diarrhea caused by antibiotic usage, researchers from RAND Health, Santa Monica, California reported in Jama (Journal of the American Medical Association). Probiotics are microbes that protect their host and prevent diseases. The most common probiotic is Lactobacillus acidophilus, which is common in yogurt and acidophilus milk.

The authors wrote, as background information:

    "The use of antibiotics that disturb the gastrointestinal flora [microbes] is associated with clinical symptoms such as diarrhea, which occurs in as many as 30 percent of patients. Symptoms range from mild and self-limiting to severe, particularly in Clostridium difficile infections, and antibiotic-associated diarrhea (AAD) is an important reason for nonadherence with antibiotic treatment."

Probiotics can restore or maintain gut microeconlogy, either during or after taking antibiotics.

The researchers added:

    "There is an increasing interest in probiotic interventions, and evidence for the effectiveness of probiotics in preventing or treating AAD is also increasing."

Susanne Hempel, Ph.D. and team set out to determine how effective probiotic usage might be in the treatment or prevention of AAD (antibiotic-associated diarrhea). They gathered information on various databases to identify RCTs (randomized controlled trials) involving AAD and probiotics, specifically Lactobacillus, Bifidobacterium, Saccharomyces, Streptococcus, Enterococcus, and/or Bacillus. They eventually identified 82 trials.

Most of the trials used interventions with Lactobacillus on its own, or together with other genera. Of all the RCTs they examined, 63 gave data on how many participants had diarrhea and how many had been randomized to both treatment groups. Out of a total of 11,811 participants, they found that there was a 42% lower risk of developing diarrhea among those on probiotics compared to those who were not.

The authors added that their results were consistent across several subgroup and sensitivity analyses. They also noted there there are still considerable differences across studies in pooled results; there is not enough evidence to determine whether this association differs according to population, types of probiotics, and the type of antibiotic prescribed.

The authors concluded:

    "In summary, our review found sufficient evidence to conclude that adjunct probiotic administration is associated with a reduced risk of AAD. This generalized conclusion likely obscures heterogeneity in effectiveness among the patients, the antibiotics, and the probiotic strains or blends. Future studies should assess these factors and explicitly assess the possibility of adverse events to better refine our understanding of the use of probiotics to prevent AAD."

Current Meds ; Viramune, Epzicom, 20mg of Atorvastatin, 25 mg of Hydrochlorothiazide.
Amlodipine Besolate 5mg-- Updated 9/24/2017

Diagnosed positive in 1985,.. In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started on  HAART on October 24th, 2003.

 As of 9/18/2017,  Viral load remains <40
CD 4 @358 /  CD4 % @ 13

 65 years young.

Offline tednlou2

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I just saw a study of mice who were fed yogurt.  The ones fed yogurt had better health, lived longer, and had a shinier coat.  I eat yogurt daily.  I'm waiting for my coat to be shinier.

Offline Ann

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  • It just is, OK?
    • Num is sum qui mentiar tibi?
I'm waiting for my coat to be shinier.

Post a pictar when it does. :D
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Miss Philicia

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I just saw a study of mice who were fed yogurt.  The ones fed yogurt had better health, lived longer, and had a shinier coat.  I eat yogurt daily.  I'm waiting for my coat to be shinier.

pizza flavored yogurt?
"Ive slept with enough men to know that Im not gay"


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