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Author Topic: "Do We Really Need Primary Prophylaxis for OIs Anymore?"  (Read 1546 times)

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Offline tednlou2

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Offline jkinatl2

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Re: "Do We Really Need Primary Prophylaxis for OIs Anymore?"
« Reply #1 on: May 07, 2012, 02:49:33 AM »
As someone who got PCP when he went off meds, I rather think that prophylaxis therapy might still be relevant for those with low CD4 counts.

Why add a "giant" Bactrim pill? Why not add a tiny Dapsone pill?

PCP and MAC might only happen to one in a few hundred people with seriously comprised immune systems. So maybe we ought to just write them off in favor of the non-event that AIDS has become.

Sick people are embarrassing anyhow.

"Many people, especially in the gay community, turn to oral sex as a safer alternative in the age of AIDS. And with HIV rates rising, people need to remember that oral sex is safer sex. It's a reasonable alternative."

-Kimberly Page-Shafer, PhD, MPH

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Offline Hellraiser

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Re: "Do We Really Need Primary Prophylaxis for OIs Anymore?"
« Reply #2 on: May 07, 2012, 02:51:55 PM »
Hmmmm.  I think the doctor is just expressing a concern that the added pill burden for someone who is already having difficulty for whatever reason may not be completely necessary.

In fact he's saying it needs to be studied more but every study they've tried to conduct had such a minor incidence of these OIs that they couldn't get enough data to support an argument.

It's interesting to me that without prophylaxis OI prevalence decreases.  That doesn't seem to make any sense.  Traditional thought would be under 200 means you're susceptible to these disease, but the doctor is subdividing into under 200 on ART and off of it.


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