Welcome, Guest. Please login or register.
November 23, 2017, 04:12:32 PM

Login with username, password and session length

  • Total Posts: 722723
  • Total Topics: 58738
  • Online Today: 333
  • Online Ever: 1421
  • (August 13, 2016, 05:18:44 AM)
Users Online
Users: 5
Guests: 292
Total: 297


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: My apologies...  (Read 1996 times)

0 Members and 1 Guest are viewing this topic.

Offline unfair

  • Member
  • Posts: 6
My apologies...
« on: September 27, 2006, 01:26:01 AM »
Let me first of all beg for forgiveness if I sound totally navie but as I mentioned that its my brother who's infected-I am trying my level best to be of useful help to him in such a trying period.  Well, after the first few frequent visits to the doctors and clinics, he's been put on medication.
I have been running some researches so that we can understand his medications better and what are the alternatives and side effects and the like. I came up with some names that got me rather confused ???
. Here's a list of what I found:

I read each of the descriptions but I would like to have a better view from those who have used any of these medications before or still using them.
Thanks for helping me out, I appreciate any help.

Sorry for the long post :(

Offline Ann

  • Administrator
  • Member
  • Posts: 28,138
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: My apologies...
« Reply #1 on: September 27, 2006, 06:23:21 AM »
Hi Unfair,

I've split your post out of the thread you posted it in, as it was a hijack of that thread. It will be easier for someone to answer you when you post your questions in your own thread. To start your own thread, look at the top of the main Living With page (for example, use the main page of the appropriate forum) and click on the button on the upper right hand side that says "new topic".

It might also help if you give us more background on yourself and more importantly, your brother.

If you look at the top left hand corner of any forum page, you'll see links to other sections of this website. One is called drugs and you'll find very good information there. Please also read the Welcome thread near the top of this forum for more information about what is available on this website.

And please don't feel like I've just told you off; I realise you are probably new to internet forums and don't yet know how they work. That's ok! We all have to start somewhere. ;)

Condoms are a girl's best friend

Condom and Lube Info  

"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline newt

  • Member
  • Posts: 3,896
  • the one and original newt
Re: My apologies...
« Reply #2 on: September 27, 2006, 08:46:36 AM »
Hey hello,

Good that you are researching info for your brother

This five-drug combination is unusual.  Is there a special reason why your bro' needs five drugs.  If so, is there a special reason why it has to be these five drugs? Do you have access to any others?

All the drugs are effective and well-tested, but...

A normal first-time combination would be: 2 nukes plus EITHER 1 non-nuke OR 1 PI.

This combo is: 3 nukes plus 1 non-nuke AND 1 PI.

Recent studies show there's no benefit from using 3 rather than 2 nukes.  The only reasons I can imagine that your bro' is on this combination is (1) some kind of resistance makes it necessary (though I sill doubt that it's the best option) (2) Your bro's doc has got a bit enthusiastic with the prescription pad (ie is stupid).

Some good questions to ask would be:

 (1) why is my bro' on five drugs - the only correct answer to this question, other than he's allergic to all the rest of the HIV meds in the world, is "he has X mutations which mean we must use these drugs".  There is very little evidence that more than 3 HIV meds gives a better long-term response for treatment first-timers.

(2) does he have any resistance? - if they say yes, ask for a copy of the resistance report, also called a genotype - this will be a load of numbers and letter, but if you share the info here, several smart people can tell you what they mean, and the realistic treatment options. - if they say no, go back to queston 1.

All the drugs in the list have alternatives, which, resistance & availability aside, you bro' might like to consider.  Me, personally, I would deffo want to consider dropping/replacing the Zerit if possible since this is well-known for causing fat loss and peripheral neuropathy, two serious long-term side effects, in a large % of people who use it.

US guidelines recommend not using Zerit & Videx together because this increases the risk of side effects, including some acute & potentially dangerous ones.  This suggests to me that the combo is perhaps not well-thought out & there will be a better combo for your brother than the heavy 5-drug one he's on at the moment. 

This is probably all a bit brutal and technical if you are new to HIV meds. Please feel free to ask more questions. I have put links to info on each of the drugs below.

- matt


You can read about each drug in the DRUGS section of this website. I have put a link here to each drug directly.   Since anti-HIV drugs are grouped into classes depending on how they work I have grouped the drugs by class:

Non-nukes (non-nucleoside reverse transcriptase inhibitors)


Nukes (nucleoside or nucleotide reverse transcriptase inhibitors


PIs (protease inhibitors)


« Last Edit: September 27, 2006, 08:52:46 AM by newt »
"The object is to be a well patient, not a good patient"


Terms of Membership for these forums

© 2017 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.