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Author Topic: reduced response to a medication  (Read 1961 times)

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Offline whoknew

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reduced response to a medication
« on: April 09, 2011, 05:09:49 AM »
Not really sure what this means but thought I would ask here anyway.

I was talking to my dr the other day and she noted that in my file  it said I have reduced response ( slightly under the normal numbers) to AZT. This is not a medication I am on or will be on its just I have to give it to my newborn baby after I have it.

This was all part of the resistance testing when I first got diagnosed and since then I have had one child who was treated with azt to prevent transmission and am pregnant with my second. My concern is that if I have reduced response to the med how effective will it be in reducing transmission to my child , surely the baby will also have reduced response ?

very confused and my dr is away on holiday... she wasn't worried by it. I also have an undetectable viral load and I am on long term treatment that has remained the same during my pregnancy. I am due to have a cesarian for other reasons but the medication provided to my child will be AZT for 4 weeks.  If for some reason the baby comes into contact with the virus in that time then I dont want it to have reduced response to it !

ok sorry for the hormonal rant.

Offline whoknew

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Re: reduced response to a medication
« Reply #1 on: April 09, 2011, 05:11:01 AM »
ok just to clarify  :)

has anyone come across this idea of "reduced response" or "limited response "

is this the same as resitance ?

it is only just reduced ... will it still work ?

Offline Ann

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  • It just is, OK?
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Re: reduced response to a medication
« Reply #2 on: April 09, 2011, 07:42:50 AM »
Your first baby had no problems, so please don't anticipate your second one having problems. Having a reduced response is not the same thing as having an all-out resistance.

The fact that you have been undetectable for your entire pregnancy means that it is very unlikely your baby would be born poz - the AZT is mainly used for that extra little bit of insurance in a case like yours.

How much longer do you have to go now? Keep us posted!

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