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Author Topic: Vaccination against HAV/HBV under therapy (Isentress and Truvada): a question  (Read 2159 times)

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Offline dist

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  • Posts: 11
  • Italian male. If you want to know more, just ask.
Dear friends, I had seroconversion illness about a year ago. I started meds, Isentress (2 tablets/d) + Truvada (1 tablet/d), four months ago (lab data: VL undetectable, CD4>500). No significant side effects.
Now, a s+ friend urged me to start the Hep B (and A) vaccination process, since it would virtually protect me against this virus. However, I have read "somewhere" that Isentress and Viread are also effective against HBV or HCV. Could these meds reduce the "efficacy" (i.e. the ability to develop HBV antibodies) of the vaccination process as well? Thank you for your kind help, in any case.
oct08         hiv negative
jan09         tested positive
feb09         cd4 621   vl 17000    no meds
may09        cd4 604   vl 4200     no meds
aug09         cd4 578   vl 6440     no meds
nov09         cd4 489   vl 52800   no meds
feb10          cd4 522   vl 372000  no meds
mar16, 2010 started on Isentress and Truvada
apr10           cd4 500   vl <50
may10          cd4 501   vl <50
aug10           Not Yet Available
nov10           Not Yet Available

Offline max123

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  • Posts: 377
  • Carpe Diem
hi dist,

excellent question to pose to your doc.

1/86 - 6/08 (annually): neg elisa
7/09: pos elisa/pos wb
8/09: cd4 560, cd4% 35, vl 13,050
12/09: cd4 568, cd4% 33, vl 2,690
4/10: cd4 557, cd4% 29.3, vl 6,440
7/10: cd4 562, cd4% 29.6, vl 3,780

Offline Ann

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  • It just is, OK?
    • Num is sum qui mentiar tibi?
The two components of Truvada (tenofovir DF + emtricitabine) are effective against hep B (will keep it in check but will not cure it) but this will not protect you against the virus - only a hep B vaccination will do that.

Truvada will not have any effect on a hep A or B vaccination.

There is no vaccination for hep C. There is a treatment, but it doesn't always work and it involves a year on hellacious meds. Trust me, I've been there, done that.

Get your hep vaccinations. It's the smart thing to do.
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