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Author Topic: issntress and truvada question  (Read 1495 times)

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Offline tennisplayer56

  • Member
  • Posts: 25
issntress and truvada question
« on: June 25, 2010, 02:30:09 PM »
i currently take issentress and truvada. however, i take the morning combo around 9 each morning, and then take the issentress anytime between 4-6 in the afternoon. i do it because i usually eat dinner around that time and am too afraid to wait later and take the chance of forgetting my second dose of issentress. my question is is it okay to have a gap of 17 hours between doses of issentress (as oppose to 12)? im only worried cuz i read somewhere that issentress has a lower threshold for developing resistance compared to other meds.

also, does anybody know whats happening with the studies on once-a-day dosing of issentress?


Offline BM

  • Member
  • Posts: 340
Re: issntress and truvada question
« Reply #1 on: June 25, 2010, 06:18:45 PM »
I don't know much about once daily dosing of Isentress (it would be great if it's approved), but I'd say that until (if) it's approved, you'd be better off separating the doses by twelve hours. Can you set alarms in your mobile phone to help you remember the times?

Offline Billy B

  • Member
  • Posts: 385
Re: issntress and truvada question
« Reply #2 on: June 25, 2010, 06:44:06 PM »
12 hours apart on the Isentress!
VL 4420 CD4 340 CD4% 24   3/15/10 Started I&T
VL  UD   CD4 340 CD4% 26.5 05/13/10
VL  UD   CD4 360 CD4% 27.1 08/3/10
VL  UD   CD4 310 CD4% 28.4 11/22/10
VL  UD   CD4 420 CD4% 27.9 02/11/11
VL  UD   CD4 370 CD4% 26.4 06/08/11
VL  UD   CD4 360 CD4% 27.7 09/23/11
VL  UD   CD4 370 CD4% 28.3 01/20/12
VL  UD   CD4 430 CD4% 28.8 05/11/12
VL  UD   CD4 370 CD4% 28.1 09/07/12
VL  UD   CD4 390 CD4% 32.3 03/14/13
VL  UD   CD4 450 CD4% 29.8 09/10/13
VL  UD   CD4 430 CD4% 31.0 04/29/14
VL  UD   CD4 520 CD4% 34.8 11/05/15
VL  UD   CD4 440 CD4% 33.5 03/10/15
VL  UD   CD4 450 CD4% 30.5 08/23/16

Offline Inchlingblue

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Re: issntress and truvada question
« Reply #3 on: June 25, 2010, 08:13:58 PM »
I'm on this combo and when I first started I was very exact about the timing, especially because I had a viral load at the time.

I was going on a trip to a location with a four hour time difference and I asked Dr. Gallant about the timing. He said it would not be a problem to switch over to the new time, essentially four hours late. I was already undetectable for almost a year.

It looks pretty likely that Isentress will be approved for once a day but it has not happened officially. There are several people on these forums already taking it once a day, with their doctors' approval.

It's hard to answer your question because your situation is different from going on a trip and switching over to a new time zone, you are basically taking it up to 5 hours late every day.

Maybe you can ask Dr. Gallant or one of the doctors on thebody.com and see what they say?




Offline aztecan

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  • Posts: 5,517
  • 32 years positive, 60 years a pain in the butt
Re: issntress and truvada question
« Reply #4 on: June 26, 2010, 12:04:49 AM »
Usually, a twice-a-day med should be taken about 12 hours apart.

I would ask your doctor about it.


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