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Author Topic: Inovio's new Optimized DNA vaccine SynCon (TM) more powerful than Ad5  (Read 2669 times)

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Offline veritas

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Inovio's new SynCon (tm) DNA vaccine showed longlasting and superior immune response in non-human

primates compared to the Ad5 vector vaccine in head to head comparison. The therapeutic vaccine, SynCon (tm), seems almost ready for phase 1, see the pipeline:



The company has both therapeutic and preventative vaccines in clinical trials at present.


Offline veritas

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Re: Inovio's new Optimized DNA vaccine SynCon (TM) more powerful than Ad5
« Reply #1 on: September 13, 2010, 10:58:58 AM »

Inovio's novel gene immunoadjuvant seems to be moving right along. The first link shows significant immune response in non-human primates:


The second link shows unprecedented immune response in HUMAN phase 1 clinical trial for cervical dysplasia and cancer caused by HPV:


UPENN has picked up the novel approach as a possible therapeutic for HIV and has completed the IND with the next step being phase 1 clinical trial for therapeutic hiv vaccine. See pipeline:


Neat stuff!



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