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Author Topic: Truvada interaction with Canasa  (Read 1292 times)

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Offline hypozsc

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  • Posts: 15
Truvada interaction with Canasa
« on: November 19, 2009, 03:29:13 PM »
I have been taking a combonation of meds which includes Truvada. Recently I was prescribed Canasa suppositories for a non-HIV related issue. I checked online before I got the new prescription filled and found a major interaction between those meds. I mentioned this when I got another prescription filled but was told they did not get any interaction warning. I called my ID doctor and they also checked and did not get a warning through their sources. I provided my doctor with the info I found and have now been advised not to use the Canasa. My question is why did I find this interaction right away online and the pharmacist and doctors did not? I don't know what source to trust any more!

Offline newt

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Re: Truvada interaction with Canasa
« Reply #1 on: November 19, 2009, 06:32:01 PM »
You can check your meds on AIDSMEDS using the Treatment > Check Your Meds link

The caution here is the tenofovir in Truvada and the Canasa are both excreted via the kidneys. There is no interaction as such. Reduced kidney function may raise the levels of both drugs because they take longer to leave the body ( generally = more side effects and potential kidney damage).

However, this is just a caution, and applies to all drugs excreted using the kidneys when taking tenofovir.

The key management method is to check your kidney function regularly.

If you get side effects the dose can be reduced - there are formulas for this - tho in the case of Truvada it will mean splitting the drug into its components therefore 2 tablets.

An alternative is of course to switch to a combination without tenofovir therefore removing the kidney excretion issue.

Hope this helps

- matt
« Last Edit: November 19, 2009, 06:33:38 PM by newt »
"The object is to be a well patient, not a good patient"


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