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Author Topic: immune reconstitution syndrome ?  (Read 997 times)

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Offline ByTheBay

  • Member
  • Posts: 26
immune reconstitution syndrome ?
« on: October 12, 2009, 01:05:18 AM »
I've been on meds for one week, and have started to experience flu like symptoms.  My doctor told me to research "immune reconstitution syndrome" given my very rapid decline (CD4 of just 53 less than 6 months after conversion).  Can anyone comment on this or share any experience?
3/12/2009 Tested Negative
5/22/2009 Tested Negative
9/17/2009 Tested Positive
9/25/2009 CD4 53  (10%) VL 57,305
9/28/2009 CD4 62  (7% )  VL: 57,305
10/3/2009 Started Truvada/Norvir/Prezista/ Septra/Bactrim and Rifabutin
11/02/2009  CD4  67 (15%) VL: 626
12/21/2009  CD4  56 (10%) VL: Undetectable
03/22/2010  CD4  46 (10%)  VL: Undetectable
06/23/2010 CD4 61 (13%) VL: Undetectable

Offline freaky_dream

  • Member
  • Posts: 132
  • mmm
Re: immune reconstitution syndrome ?
« Reply #1 on: October 12, 2009, 01:24:50 AM »
Don't have any experience with IRS but it sure sounds like it. You have to realize the reason we get symptons like coughing, sneezing, fever and such isn't because the virus causes it directly. It is our immune system going on the attack(it's the reason they say that swine flu is most dangerous to those who have a healthy immune system). So if your immune system is extremely compromised like yours is when the drugs start controlling the virus your tcells start up again causing the inflammatory response.

Offline mecch

  • Member
  • Posts: 13,362
  • red pill? or blue pill?
Re: immune reconstitution syndrome ?
« Reply #2 on: October 12, 2009, 05:35:49 AM »
Did he/she tell you that you have IRS or just to research it as a hypothesis?

My gut is you'll be feeling a lot of turmoil -- IRS for example -- and then have great results pretty quickly.  Your virus load is lowish considering that your CD4 were decimated, maybe that means you have really active immune response. 
“From each, according to his ability; to each, according to his need” 1875 K Marx


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