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Author Topic: CD4 Fluctuation, I'm confused...  (Read 3812 times)

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Offline ShyGuy101

  • New Member
  • Posts: 2
CD4 Fluctuation, I'm confused...
« on: May 29, 2009, 11:58:39 PM »
Hi Everyone... This is my first post here, but have found SO much useful information, thanks for sharing your experiences...

I starting taking Atripla in early March '09 with a viral load of 95,000 and CD4 of 301.  This is the first HIV med i have ever taken, and experienced the typical side-effects early on... Vivid dreams, dizziness, a very mild rash, but all of that has subsided now, so no major issues with it...

After only one month on Atripla, my viral load was down to 1042, and CD4 was up to 424... Needless to say, I was THRILLED! 

I got my second round of labs today (after about 2.5 months of therapy) and my viral load is down to 220 (hooray!), but my CD4 dropped to 268.... I am so disappointed at the drop in CD4... 

I had such high hopes for this second round of labs, maybe too high...

Has anyone else had this experience?  Or can anyone shed some light on what may be going on?

I got the results in the mail this afternoon, so I haven't had a chance to touch base with my doc, but i plan on following up next week...

Thanks everyone...

Offline aztecan

  • Member
  • Posts: 5,517
  • 32 years positive, 60 years a pain in the butt
Re: CD4 Fluctuation, I'm confused...
« Reply #1 on: May 30, 2009, 12:07:04 AM »
Hey Shyguy,

Don't fret the bouncing CD4s. The Atripla is doing its job and, from the sound of it, very well.

The meds fight the virus, so what you want to see when you start ARV therapy is a drop in the viral load.

Yours went from 95,000, to 1,042, then to 220.

I think a hooray is in order. That is fantastic!  ;D

OK, so your CD4s are bouncing around a bit. That is absolutely normal.

Mine have been known to go up and down by 200 to 300 from one test to another. The CD4 can also differ depending on the time of day you did the test, plus a host of other variables.

Sometimes it takes time for the CD4s to climb.  Be patient and I'm pretty sure you will be happy with the results down the road.



"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline ShyGuy101

  • New Member
  • Posts: 2
Re: CD4 Fluctuation, I'm confused...
« Reply #2 on: May 30, 2009, 12:18:23 AM »
Thanks Mark, appreciate that very much! 

And you're right, the dramatic drop in viral load is a GREAT thing, i definitely know the Atripla is doing it's job... I think I just made an assumption (and you know what they say about assuming, huh?) that the CD4 would continue to climb as quickly as it did in the first 30 days.... Probably an unrealistic expectation on my part...

Thanks again for the post, it really helps!


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