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Author Topic: Combo still good n effective after 10 years...  (Read 2378 times)

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Offline newt

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  • the one and original newt
Combo still good n effective after 10 years...
« on: August 07, 2006, 05:06:29 AM »

AIDS drugs still effective after 10 years

News from the massive Antiretroviral Therapy Cohort Collaboration...

"Ten years after they were introduced in Europe and North America, HIV/AIDS drugs are still effective but many patients are not being put on them soon enough, scientists said on Friday.

Experts had feared the AIDS virus would become resistant to the treatments and deaths would increase but research published ahead of an international AIDS conference in Toronto later this month has shown it has not happened.

The combinations of drugs reduce mortality and progression to AIDS by about 80-90 percent but tuberculosis (TB) has become a deadly co-infection in patients.

"Ten years on these treatments still work as well as they did initially (but) there is a change in terms of TB becoming more important," said Professor Matthias Egger, of the University of Bern in Switzerland, said in an interview.

He said people should be diagnosed and start treatment earlier.

"If that would happen these drugs would even achieve more."

The findings of the Antiretroviral Therapy Cohort Collaboration reported in the Lancet medical journal are based on an analysis of data on more than 22,200 HIV positive people in Europe and North America who started treatment between 1995 and 2003." etc

People who started treatment with a CD4 of 350+ did better, very well even (see page 2).  This and other research is leaning me towards saying start treatment before your CD4 falls below 350 (like US guidelines), not 200 (as per UK).

- matt
"The object is to be a well patient, not a good patient"

Offline jordan

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  • What I want is a celebration
Re: Combo still good n effective after 10 years...
« Reply #1 on: August 07, 2006, 05:52:26 AM »

this is great news - thanks for sharing.....I just had my TB test and it came back negative.
If you think your lonely now, wait until tonight.

Offline aztecan

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  • Posts: 5,517
  • 32 years positive, 60 years a pain in the butt
Re: Combo still good n effective after 10 years...
« Reply #2 on: August 07, 2006, 09:42:33 AM »
Hey Newt,
Thanks for the article. It reinforces what I still believe, its better to start treatment while a substantial amount of the immune system is intact rather than waiting until it is weakened severely or the threashold to AIDS is crossed.

By the way, as you know, this is my 10th year on the same meds. They're still working.


"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)


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