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Author Topic: Long-term side effects of Atripla?  (Read 11706 times)

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Offline Dave32807

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  • Posts: 4
Long-term side effects of Atripla?
« on: November 22, 2008, 04:51:01 PM »
I have been on Atripla for a little over 2 years now. Numbers are still where they should be--VL UD and CD4 over 700. No side effects except for the occasional vivid dream. I am concerned about long-term side effects (like from today going forward) and treatment failure.

I have asked my doctor about long-term side effects and he said the combination is still too new to say. I have also asked him about the likelihood of my needing to switch treatment and if so, when.  He said he really didn't have an answer.  I know that 2 years is a relatively short amount of time to be talking about "long-term" side effects and treatment failure, but I believe they are valid concerns of mine.

Offline Iggy

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  • Posts: 2,434
Re: Long-term side effects of Atripla?
« Reply #1 on: November 23, 2008, 07:29:54 AM »
Hi Dave,

I'm going to offer the non-scientific answer. I believe both you and your doctor are basically correct.

There has not been enough time to study long term effects ( I assume you mean 10+ years) of Atripla use, but you are correct when you state you feel this is a valid concern.

From my perspective there are three key things that you can and should be doing right now to address your concern.

The first research Atripla and the components of it so that you understand all that we do already know about it.

The second is to moinitor your lab results not just for CD4's and VL but for other vital levels such as chlosteral, sugar levels, etc.  Talk to your doctor about which one's are important for you two to keep and eye on and discuss based on your general health and your family's medical history.

The third is what you are doing now: asking questions.  Ask them here, ask them as you read, and ask your doctor about this with every result and until you two come to an understanding of what you need to know whenever he has new information for your records.


Offline Dave32807

  • Member
  • Posts: 4
Re: Long-term side effects of Atripla?
« Reply #2 on: November 23, 2008, 01:56:11 PM »

Thank you so much. Especially for the advice on paying attention to other lab results.  I had never thought of that.  I'm going to see him again in February and I have a running list of questions.

Take care, and thanks again!  I really appreciate your taking the time to answer my concerns.


Offline jayjax

  • Member
  • Posts: 83
Re: Long-term side effects of Atripla?
« Reply #3 on: November 30, 2008, 02:46:45 PM »

You have very valid concerns, regarding any long term side effects. One of the best ways to keep track of any side effects is a forum like this as well as discussing any concerns with your doctor.  Granted, 2 years is a very short time.  I've only been on Atripla for a couple of weeks but it still a concern of mine.

Like you, I want to know all the information possible about a drug I'm taking. I'm glad to hear your CD4 and VL results are good so far. 

Keep posting and don't hesitate to address any concerns regarding new meds.

08 Oct 08:  Diagnosed
18 Oct 08:  1st Lab Work: CD4 - 268, VL 7,000
18 Nov 08:  Started Atripla
28 Jan 09:   CD4 - 195, VL 70
05 May 09:  CD4 - 201, VL = Undetectable
16 Aug 09: CD4 - 235, VL = Undetectable
30 Nov 09 CD4 - 300, VL = Undetectable
30 Mar 10 CD4 - 305, VL = Undetectable
27 Jul 10 CD4 -  301, VL = 100
13 Aug 10 -- Switched to Truvada/Reyataz/Norvir
30 Sep 10 --  CD4 598, VL = Undetectable

Offline Dave32807

  • Member
  • Posts: 4
Re: Long-term side effects of Atripla?
« Reply #4 on: November 30, 2008, 03:25:44 PM »
Thanks for the response, Jay.  I appreciate that other people are interested in my concerns.  It's just frustrating that when I Google "Atripla Long-Term Side effects" the only things  I see are about the rash and the dreams and those are not what I am concerned about.  I am concerned about facial wasting, neuropathy, fat redistribution and the like.  Sustiva has been around for 10 years, Viread for 7 years, and Emtriva for 5 years.  Haven't some people been on a combination like this Atripla for at least 5 years and if so, do any of them report side effects like I mentioned above or others?


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