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Author Topic: ah, the ubiquitous CD4 drop....bummer.  (Read 1288 times)

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Offline todd123

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  • Posts: 67
  • "You don't ask, you don't know."
ah, the ubiquitous CD4 drop....bummer.
« on: November 11, 2008, 06:03:58 PM »
Hey everyone,

Just got back from the doc with the new labs.  The good news: VL keeps dropping now down to
156 from 367.  The not-as-good news:  CD4's went from 135 to 105.  I initially had a huge jump
percentage-wise from 16 to eventually the 135.  My helper percentages have gone up also from
2% to 6% to 9%.
If all this weren't coupled with recent aches and pains and night sweats I wouldn't be AS bummed.
One or the other but not both, you know?
But I know that's not how this all works.  I practically had no immune system when diagnosed (oddly enough,
with NO OI's-a miracle in intself) 

It seems like I'm just going to have to be patient for this next year and BREATHE.  I'd love the molloscum to
vanish, but that too is slow. 

I know it's all the things we've heard before, I just had to share it with people that understand the anxiety
and fear around it. 

Any encouraging thoughts would be awesome.

Thanks to my brothers and sisters,

Tested HIV+ July 28, 2008
CD4 16 VL over 400,000
Started Prezista/Norvir, Isentress and Intelence; Mepron
8/08   CD4 64    2%      VL 1500
9/08   CD4 135  6%      VL 371
11/08 CD4 104   9%     VL 156
12/08 CD4 161   9%     VL 400
01/09 CD4 109   7%     VL 351
02/09 CD4 218   8%     VL   98
03/09 CD4   80   5%     VL   98 at least that's the same
04/09 CD4 150   7%      VL 100
05/09 CD4 232   8%      VL   90

Offline BT65

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Re: ah, the ubiquitous CD4 drop....bummer.
« Reply #1 on: November 11, 2008, 06:32:36 PM »

You started out with pretty low CD4's and a pretty high vl.  Your numbers have improved since that time, so I would just have patience.  It takes awhile with numbers that low to get them above 200 (usually), and they can blip a bit during that time.  You just hang in there.
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Offline Assurbanipal

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Re: ah, the ubiquitous CD4 drop....bummer.
« Reply #2 on: November 11, 2008, 07:27:05 PM »

Looks like you are getting the viral load down very quickly (to under 400 copies in less than 3 months) and did I read it correctly that your CD4 percentage went up from 2% to 6% to 9%?  That's a good increase and it sounds like you are controlling the virus and your immune system is starting to come back.

The absolute CD4 count is a number that varies a lot just due to random factors (you know maybe a few of them stopped to chat and missed the blood draw  :) )  Seriously, the CD4 percentage is a somewhat less variable measure to look at, and if that is going up, it's good news. 

I remember how hard it is to wait for the improvements -- HATED Bactrim second only to the damned oxygen tube.  But it does look like things are improving for you and that you've had a pretty good response in the first three months as far as taking down the virus is concerned. 

Best wishes


5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%
2014 VL UD - 48
2015 VL 130 Moved to Triumeq

Offline Robert

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  • Posts: 2,658
Re: ah, the ubiquitous CD4 drop....bummer.
« Reply #3 on: November 11, 2008, 07:40:13 PM »

brother todd.

I know that bummer you're talking about but not to worry.  Like Assurbanipal says, it's the percentage that's important.  That, and the VL going in a downward direction and you seem to have a handle on that.

And considering how low you were when you're started and it's only been like 3 months since you started the meds, you're doing quite well.

 High anxiety will only keep the numbers from going where you want them to so don't have a cow.

brother robert

Offline skeebo1969

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  • Posts: 5,873
Re: ah, the ubiquitous CD4 drop....bummer.
« Reply #4 on: November 11, 2008, 09:55:22 PM »

   I agree with the others, that percentage has shown a lot improvement over the 2% you when you started the meds.  That is a great increase.  I know it is hard in the beginning but try not to fret over the Cd4 numbers.  Stressing over it will not do you well. Try to concentrate on the improvements you have made, they are very good by the way!

   There several factors that can cause your #'s to vary anyways.  It could have been the time of day you had your blood drawn or how the lab just happened to handle it that day.  That's not really that drastic of a decrease, however I know when mine were low I didn't want any jumping ship either ;)

  The way things have been improving for you thus far it shouldn't stop..  Just hang in there!
I despise the song Love is in the Air, you should too.


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