Welcome, Guest. Please login or register.
April 25, 2017, 07:49:49 AM

Login with username, password and session length

  • Total Posts: 711951
  • Total Topics: 57112
  • Online Today: 222
  • Online Ever: 1421
  • (August 13, 2016, 05:18:44 AM)
Users Online


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Finally, an acceptable ritonavir/"Norvir" formulation!  (Read 2521 times)

0 Members and 1 Guest are viewing this topic.

Offline leit

  • Member
  • Posts: 236
Finally, an acceptable ritonavir/"Norvir" formulation!
« on: July 30, 2008, 08:39:35 PM »
Within this year, Abbott will submit to the regulatory authorities the new ritonavir (Norvir) formulation in tablets making use of Meltrex technology. This technology allows not to use the oleic acid excipient, cause of dysentery.

The first data on bioequivalence with the present soft capsule formulation will be presented at the XVII International AIDS Conference (Mexico City, 3-8 August 2008).


PS My guess is that this new Meltrex formulation will also remove the need to keep ritonavir/"Norvir" refrigerated (as happened with Kaletra-Meltrex).

Offline leit

  • Member
  • Posts: 236
Re: Finally, an acceptable ritonavir/"Norvir" formulation!
« Reply #1 on: August 15, 2008, 08:31:35 AM »
The current soft gelatin capsule and the pilot tablet Ritonavir formulation (expected to be filed for approval before the end of this year) proved to be bioequivalent.

Unfortunately, also the adverse event are the same. So, it's only a matter of convenience (but important, 'cause the new tablet formulation does not require refrigeration).


Terms of Membership for these forums

© 2017 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.