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Author Topic: impact on liver  (Read 2593 times)

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Offline ANGEL265

  • Member
  • Posts: 35
impact on liver
« on: June 23, 2008, 10:40:41 AM »
Dear All,

Iam on effervinz and duovir. My cd4 is 750. However my SGOT(ALT) is 110 and SGPT(AST) is 150. My trigylicide is also high at 240 and chlostral is 228. Kindly advise my wih regard to my liver enzymes as wha should i do including change of medicines and which medicines has least impac on liver. awaiting your suggestions.

Offline aztecan

  • Member
  • Posts: 5,517
  • 32 years positive, 60 years a pain in the butt
Re: impact on liver
« Reply #1 on: June 23, 2008, 04:33:28 PM »
Hey Angel,

First, here is a link regarding hepatoxicity and the HIV meds:


Your levels are high. Have you talked to your doctor about this? Is he/she concerned?

I would definitely set up a doctor's appointment and have a heart to heart with your doc if you haven't already.

I have NASH (non-alcoholic steato hepatitis) caused by the meds. There is nothing I can do about it, but I do monitor it and there is some hope on the horizon.

Oh, by the way, I know Stocrin, but have never heard of duovir. Do you know what other names that med goes by?

The meds have a way of messing with us, so I would not let this just lay there. I would get on the horn to the doc.


"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline OutOfDarkness

  • Member
  • Posts: 90
Re: impact on liver
« Reply #2 on: June 26, 2008, 07:28:23 PM »
hi Angel,

I was diagnosed with a fatty liver and slightly elevated liver function tests before I started any hiv meds.  I had a biopsy just to make sure that was all that was going on before starting meds.  I take sustiva and truvada and not only did my liver function return to normal after being on the meds, my counts have been really good. 

I agree with Mark and talking to your doctor is a good thing.  Let us know how it goes!
2000 - seroconverted
2005 - cd4 350, VL 113,000
3/06 - started sustiva/truvada
3/08 - cd4 1,300 VL >50(undet.)

Offline lydgate

  • Member
  • Posts: 1,022
  • Virgin, can't drive
Re: impact on liver
« Reply #3 on: June 27, 2008, 02:28:16 AM »
Duovir = Combivir =AZT + 3TC = zidovudine + lamivudine.

Sustiva = Stocrin = efavirenz.
Her finely-touched spirit had still its fine issues, though they were not widely visible. Her full nature, like that river of which Cyrus broke the strength, spent itself in channels which had no great name on the earth. But the effect of her being on those around her was incalculably diffusive: for the growing good of the world is partly dependent on unhistoric acts; and that things are not so ill with you and me as they might have been, is half owing to the number who lived faithfully a hidden life, and rest in unvisited tombs.

George Eliot, Middlemarch, final paragraph


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