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Author Topic: confused about indeterminate Western blot  (Read 4028 times)

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Offline shellshocked

  • Member
  • Posts: 17
confused about indeterminate Western blot
« on: December 21, 2007, 09:49:39 AM »
I've been tested 4 times for HIV since Aug 07: Aug 30, Sept 10, Oct 9, Oct 29. If I were infected, it could not have happened after Aug 11/07. All four test results showed reactive ELISA but indeterminate (or weakly reactive) Western blot. On this basis, my doctor has diagnosed me with HIV. On Dec 11, I was tested again for confirmation, but I have not yet received those results. If a person is infected with HIV, is it possible that a Western blot result can be indeterminate/weakly reactive beyond the 3 month window period? My doctor said that in my case the Western blot may always be weakly reactive. Is that possible?

Offline shadowfluid

  • Member
  • Posts: 398
  • Mike
Re: confused about indeterminate Western blot
« Reply #1 on: December 21, 2007, 03:36:58 PM »
Mine was "mildly reactive" with the Western Blot when I was diagnosed in May.
Then I got my Vl and CD4 (350/ 40k) and I was pretty poz.
Jan 08       321/23%  VL 92,000 (very mild shingles)
Feb 1 08    Start Truvada+Viramune
March 08    470/33%  VL 320
mid-May     Start Reyataz/Norvir/Truvada
June 08      571/ 40%     VL   80
August 08   585/ 33%     VL >50
Nov  Lab error!!!!!!!!wah.
Jan 09        535      Undetectable
March 11     756

Offline HIVworker

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  • Posts: 918
  • HIV researcher
Re: confused about indeterminate Western blot
« Reply #2 on: January 03, 2008, 12:47:48 AM »
Well, it's possible but your VL is very low ...actually its really low. It could be that there isn't enough antigen to induce a response that will show up on a WB. However, you appear to have tested positive by WB and ELISA and Viral load. You should be discussing that with your doctor.

« Last Edit: January 03, 2008, 12:52:31 AM by HIVworker »
NB. Any advice about HIV is given in addition to your own medical advice and not intended to replace it. You should never make clinical decisions based on what anyone says on the internet but rather check with your ID doctor first. Discussions from the internet are just that - Discussions. They may give you food for thought, but they should not direct you to do anything but fuel discussion.


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