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Author Topic: Withania Samniferum – Ashwaganda- COUNTERACTS EFAVIRENZ???  (Read 2249 times)

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Offline avi

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Withania Samniferum – Ashwaganda- COUNTERACTS EFAVIRENZ???
« on: November 28, 2007, 11:51:20 AM »
HEY  2 specialist  ;)


2]I am on TRUVADA+ EFAVIRENZ 4 the last 4 months.

3]V.L ,undetectable &  Cd4=540  = 20%

4]I have been reading some news about boosting up CD4 with this Indian Ginsang & bought it but its  wearying me immediately upon taking.

5] is there any danger like with HYPERICUM perforatum \ST JOHN`S WORT,that counter interacts  when Combined with Efavirenz\stocrin ?

should i address this question 2 another section?




Offline Miss Philicia

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Re: Withania Samniferum – Ashwaganda- COUNTERACTS EFAVIRENZ???
« Reply #1 on: November 28, 2007, 12:00:59 PM »
Is there a reason you're not asking your doctor this question?  With any vitamin/supplement intake when you're already on HAART you should always run these things by your doctor, as many such substances cause issues... which you even mention in the thread in regards to St. John's Wort.
"I’ve slept with enough men to know that I’m not gay"

Offline avi

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Re: Withania Samniferum – Ashwaganda- COUNTERACTS EFAVIRENZ???
« Reply #2 on: November 28, 2007, 04:53:10 PM »
1]because of my doc being unaware of this herb'& his speciality 
is cross -resistance

2]cause he disapprove of  any herb intake

3]any doc who's familiar with side effects

Offline newt

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Re: Withania Samniferum – Ashwaganda- COUNTERACTS EFAVIRENZ???
« Reply #3 on: November 29, 2007, 06:19:24 AM »
It is very likely that St John's Wort increases the rate of efavirenz processing in the liver.

Therefore taking St John's Wort  with efavirenz may well reduce the concentration of efavirenz in the body, possibly to useless levels.  This will lead to resistance and viral rebound, therefore increased CD4 cell loss.

There has been no formal study of this interaction. This is a position based on St John's Wort  known effects on other medicines processed by the liver in the same way as efavirenz.

Recommendation is: do not take St John's Wort with efavirenz.

A summary of medicines that don't go well with St John's Wort is here

- matt
"The object is to be a well patient, not a good patient"


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