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Author Topic: cART  (Read 1591 times)

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Offline John2038

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« on: October 22, 2007, 02:00:34 PM »
What is new in this research  ?


[EDIT]: Removed initial content of my post, as it doesn't seems to the links are really interesting.
« Last Edit: October 22, 2007, 02:39:27 PM by John2038 »

Offline newt

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Re: Good news: Researchers Knock Out HIV ?
« Reply #1 on: October 22, 2007, 02:31:04 PM »
In short it means if you take combo for long enough (some undefined period of years, perhaps several+ years) your CD4 is likely to go back above 500 (based on large cohort observations).

I agree with the drift at a population level, and this is a good result, but I personally would take issue with some of the language eg "successfully neutralise the HIV virus". Combo is made up of virostatic drugs, ie they stop the virus replicating, but they do not kill it at such.  There are many problems with successfully neutralising HIV with combo. Plus the article does not refer to the significant proportion of people, for reasons of adherence (ah, yes, the magic bullet) and otherwise (eg resistance, drugs just not working for them, some other reason) do not get a good immunological or virological response. Or long term metabolic side effects of meds.

Combo is a result in the way Hamilton coming 2nd in the Grand Prix is a result, bloody amazing for a rookie driver's 1st time out, but not the top prize.

- matt
"The object is to be a well patient, not a good patient"


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