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Author Topic: pregnancy while on sustiva  (Read 3703 times)

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Offline kitty1

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  • Posts: 66
pregnancy while on sustiva
« on: September 20, 2007, 10:02:45 PM »
I recently got married and am considering getting pregnant with the evil depo provera gets out of my system.  I went to see my ob-gyn at the ryan white core center where i go.  i asked her what the serious consequences where if i got pregnant while on sustiva.  surprisingly she told me there has been no problems so far.  She says the reasearch was done on rats and not people.  She says none of her positive patients that have conceived while on sustiva have had any problems.  Not to say it may not happen.

i felt releaved.  I thought it was very deadly.

Offline Ann

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  • Posts: 28,138
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: pregnancy while on sustiva
« Reply #1 on: September 21, 2007, 08:11:28 AM »
Hi Kitty,

Sustiva (aka efavirenz) is NOT recommended for use during pregnancy. From the iBase info:

Efavirenz is not recommended in pregnancy. This drug caused neural tube defects (brain damage) in the developing foetus in a single animal study.

So far there are no reports of increased risk of neural tube damage in human babies. But, if other treatment options are available, there is a strong caution against its use.

This is most important during the first 12 weeks of pregnancy when the neural tube is developing.

If you are already 12 or more weeks pregnant and have been taking efavirenz during this time you will need two tests.

Please read the entire page on pregnancy and hiv meds here.

The whole document on pregnancy and hiv can be downloaded by clicking here. Please note it is a PDF document. It's very up to date - published in July 2007. While it is based on UK treatment guidelines, the information is also valid in the US.

I'm surprised this doctor would take such a relaxed attitude to taking sustiva during pregnancy. It just doesn't seem worth the risk to me, especially when there are other, less dangerous, options available.

Keep us posted, Kitty. And good luck putting a bun in the oven! ;)

« Last Edit: September 21, 2007, 08:17:30 AM by Ann »
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Offline mesu

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  • Posts: 55
Re: pregnancy while on sustiva
« Reply #2 on: October 15, 2007, 11:34:59 AM »

I may need to start meds soon. As discussed with the nurse in the clinic, i was told that they do not recommend sustiva for women who may want to get pregnant in the future. Does it mean that this is not an option for me at all (as i may want to have babies one day)?

Can women take sustiva and then switch to another drugs if they want to get pregnant?


Jan/Feb 07 - infected :(
Sept3: cd4 162; 13.5% VL 24,000
Oct5: cd4 68 13.6%
Nov6: cd4 205  14.64%
Dec10,07: cd4 188  15.67%  VL: 9900
FEB15,08: cd4 242 18.62%
Mar10/08: cd4 219 15.64%  VL: 7300
May26,08: start Truvada and Sustiva
July 18,08: cd4 255, 18.50%, VL undetectable (<75)
Nov 4,08: cd4 380, 27.14%,
Feb 6,09: cd4 296, 22.7%,
May 26: cd4 351, 27%,
Aug 28: cd4 310, 28%,
Dec 2009: cd4 321, 35.67%,
March 2010: cd4 325, 32%,
June 2010: cd4 385, 29.5%,
Sept 2010: cd4 368, 30.75%,
Feb 2011: cd4 431, 43.1%,
Jun 2011: cd4 433, 30.93%,
Sept 2011: cd4 435,  36 %,
Jan 2012, cd4 467, 33.36%
May 2012: cd4 421, 38.21%,
Sept 2012: cd4 393, 30.23%,
VL: undetectable since July 08

Offline HealthyMomma

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  • Posts: 128
Re: pregnancy while on sustiva
« Reply #3 on: October 15, 2007, 03:16:52 PM »
I was on Sustiva and soon as I found out I was pregnant my doc switched me to something else...I cant remember what it was though...


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