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Author Topic: New Insight Into HIV Infection  (Read 2112 times)

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Offline J220

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New Insight Into HIV Infection
« on: May 04, 2007, 04:11:40 PM »
New Insight Into HIV Infection ( from http://www.sciencedaily.com/releases/2007/05/070504131255.htm )

Science Daily Scientists provide new information about how HIV, the virus that causes AIDS, enters the nucleus of an infected cell. This study could help devise a new way to fight AIDS.

When HIV infects a cell, it carries its DNA into the nucleus of the cell, then the viral DNA mixes with the cell's DNA. The combined DNA produces proteins that make new viruses, which spread to neighboring cells. The mechanism by which HIV's DNA enters the nucleus is not yet fully understood and may offer new ways to fight HIV.

Xiaojian Yao and colleagues studied how various cellular proteins help the virus enter the infected cell's nucleus. They revealed new roles for these proteins that had not been fully established. The study also showed that by silencing genes that produce one of these proteins, HIV was three times less infectious than when the protein was present.

Article: "Interaction of Human Immunodeficiency Virus Type 1 Integrase with Cellular Nuclear Import Receptor Importin 7 and its Impact on Viral Replication" by Zhujun Ao, Guanyou Huang, Han Yao, Zaikun Xu, Meaghan Labine, Alan W. Cochrane, and Xiaojian Yao

Note: This story has been adapted from a news release issued by American Society for Biochemistry and Molecular Biology.
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Offline risred1

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Re: New Insight Into HIV Infection
« Reply #1 on: May 04, 2007, 10:53:08 PM »
I just have to say, there is some amazing shit going on! (excuse my french!)

If anyone things there is a global conspiracy, its exactly this type of research that is going on that is changing everything we know not just about HIV but about how VIRUS's really work.

There was a time that Vaccine was the only approach, Anti Viral drugs are now becoming quite common!

risred1 - hiv +
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Offline appleboy

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Re: New Insight Into HIV Infection
« Reply #2 on: May 05, 2007, 08:41:10 AM »
They are getting closer and closer!  Lets keep on playing with cells.  Some how I think stem cell research is going to play a big part in this at some point.
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Offline Zanarkand

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Re: New Insight Into HIV Infection
« Reply #3 on: May 06, 2007, 11:32:30 AM »
Learn something new everyday 'eh. ^_^
Agreed, cellular modification will also lead to many good things in the near future.
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