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Author Topic: Grapefruit exaggerates the effects of certain drugs?  (Read 4422 times)

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Offline Ihavehope

  • Member
  • Posts: 1,366
  • Yes, I'm a cry baby, AND WHAT?
Grapefruit exaggerates the effects of certain drugs?
« on: April 02, 2007, 11:27:23 AM »

Scientists have known for a while that grapefruit exaggerates the effects of certain drugs, sometimes with dangerous results. They just weren't sure why.

Now they have the answer: furanocumarins, chemicals found in only three citrus fruits -- grapefruits, pomelos and Seville oranges. Even very small amounts -- "sub-micro levels" -- can cause potentially hazardous interactions with some medications, according to Paul Watkins, professor of medicine at the University of North Carolina at Chapel Hill, who led the research team. "You can't taste them . . . but they are very powerful," he adds.

Infected: April 2005
12/6/06 - Diagnosed HIV positive
12/19/06 - CD4 = 240  22% VL = 26,300
1/4/07 - CD4 = 200 16% VL = ?
2/9/07 = Started Kaletra/Truvada
3/13/07 = CD4 = 386 22% VL ?

Offline aztecan

  • Member
  • Posts: 5,517
  • 32 years positive, 60 years a pain in the butt
Re: Grapefruit exaggerates the effects of certain drugs?
« Reply #1 on: April 02, 2007, 06:29:44 PM »
Yes, I know. I haven't had a grapefruit in years.

I do love them though, usually with just a bit of salt on top.




(Who can at least appreciate the memory of grapefruit)
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline J.R.E.

  • Member
  • Posts: 7,542
  • Joined Dec-2003 Living positive, since 1985.
Re: Grapefruit exaggerates the effects of certain drugs?
« Reply #2 on: April 02, 2007, 06:59:37 PM »

I never did like grapefruit juice. Every once in a while, when I purchase orange juice, I swear there is grapefruit juice in it. ( not much , but I can tell. )


Current Meds ; Viramune, Epzicom, 20mg of Atorvastatin, 25 mg of Hydrochlorothiazide.
Amlodipine Besolate 5mg-- Updated 9/24/2017

Diagnosed positive in 1985,.. In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started on  HAART on October 24th, 2003.

 As of 9/18/2017,  Viral load remains <40
CD 4 @358 /  CD4 % @ 13

 65 years young.

Offline JohnOso

  • Member
  • Posts: 817
Re: Grapefruit exaggerates the effects of certain drugs?
« Reply #3 on: April 04, 2007, 12:38:17 PM »
I've heard about the grapefruit interactions, and as with Mark, I haven't had any fruit or juice for a long time.

I didn't know about the pomelo though (and I have no idea what a Seville orange is).



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