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Author Topic: Backup Treatment for Drug-Resistant Gonorrhea  (Read 2493 times)

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Offline Jim Allen

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Backup Treatment for Drug-Resistant Gonorrhea
« on: May 07, 2019, 12:11:55 pm »
Not HIV related but still interesting. Ill be honest the emergence of drug resistant STI's do worry me.

Full write-up
https://www.poz.com/article/new-combo-work-backup-treatment-drugresistant-gonorrhea

In Short:
Quote
New Combo Could Work as Backup Treatment for Drug-Resistant Gonorrhea
However, because this combo is not as effective as the current standard treatment, the search for new options continues.

The participants were randomly assigned to receive a single intramuscular injection of either 240 milligrams of gentamicin or 500 mg of ceftriaxone plus an oral dose of 1 gram of azithromycin.

A total of 1,762 people were screened and 720 people were enrolled in the study between October 2014 and November 2016. A total of 358 people were assigned to the gentamicin group while 362 were assigned to the ceftriaxone group; results were available for 306 (85%) and 292 (82%) members of each group, respectively.

Two weeks after treatment, 299 (98%) of those in the ceftriaxone group and 267 (91%) of those in the gentamicin group were cleared of gonorrhea. Of the 328 people who had a genital infection, 151 of 154 (98%) and 163 of 174 (94%) of those in the ceftriaxone and gentamicin groups were cleared of the STI, respectively. Of those with a throat infection, the cure rates were 96% and 80% in the two study groups, respectively. And of those with a rectal infection, the cure rates in the two study groups were a respective 98% and 90%.
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