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Main Forums => I Just Tested Poz => Topic started by: beanstalk on October 10, 2018, 04:42:51 pm

Title: Do subtypes matter?
Post by: beanstalk on October 10, 2018, 04:42:51 pm
Quick question. I know there are many HIV subtypes, but what exactly are the differences between them? Does treatment affect them in different ways? I googled for it but the only things I found out is type B is more common in the "developed" world, that my type (G) is found in Nigeria and that type D progresses faster.
Title: Re: Do subtypes matter?
Post by: Jim Allen on October 10, 2018, 05:15:49 pm
Some are less wide-spread and some show slower progression than others.

On your treatment, ultimately the proof will be in the pudding like everyone else.
Your treatment will either suppress HIV and that's fine, or after 6-9 months it will not and you will need to switch treatment/adjust the treatment.

The good news is the genotype is examined when starting treatment for the presence of specific genetic mutations that are known to cause resistance to certain drugs and even though its true in regards to sub-type most treatment is focused/developed on HIV 1 "B" the meds are effective at suppressing on other sub-types.

Some meds better than others of course, and I am sure your doctor was aware of this when selecting the best treatment.

Not at my laptop right now but the avert intro always I thought was reasonably good starting place. I sure someone will jump in before I make it to my laptop with more info.

Jim

https://www.avert.org/professionals/hiv-science/types-strains
https://academic.oup.com/cid/article/48/9/1296/410454
Title: Re: Do subtypes matter?
Post by: Loa111 on November 15, 2018, 08:25:38 am
My clinic does not test of actual Subtypes, as I asked twice what subtype I am, just curious really.  Treatment is working, UD now, so that's the main thing.