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Meds, Mind, Body & Benefits => Questions About Treatment & Side Effects => Topic started by: yogalover on August 12, 2013, 08:32:25 am

Title: low dose naltrexone
Post by: yogalover on August 12, 2013, 08:32:25 am
Does anyone know anything about low dose naltrexone? My friend has ms and is taking it and keeps telling me about it for hiv!!I had never heard of it and have done a little bit of research but still don't really know what it is or does
Title: Re: low dose naltrexone
Post by: Matts on August 12, 2013, 11:50:49 am
You should find a lot of information in the Net, par exemple
http://www.lowdosenaltrexone.org/ldn_and_hiv.htm (http://www.lowdosenaltrexone.org/ldn_and_hiv.htm)

I think that it is out-of-date in the western world with the modern HIV drugs. There is still some research in Africa where no HIV drugs are available, but here You can forget it confidently.
But the benefits for MS seem to be interesting.
I took low dose prednisone/prednisolone 10mg many years ago. There was a small success but nothing compared to the HIV drugs.
Title: Re: low dose naltrexone
Post by: witch on November 24, 2013, 11:43:20 am
There are newer studies from 2011 on low dose naltrexone (LDN).

LDN combined with standard ART increases CD4 and CD4% faster compared to just ART:
Impact of low dose naltrexone (LDN) on antiretroviral therapy (ART) treated HIV+ adults in Mali: A single blind randomized clinical trial. Journal of AIDS and HIV Research Vol. 3(10), pp. 189-198, September 2011
http://academicjournals.org/article/article1379515379_Traore%20et%20al%20(2).pdf (http://academicjournals.org/article/article1379515379_Traore%20et%20al%20(2).pdf)

LDN alone did not prevent CD4 drop but maintained CD4% and reduced HIV viral load:
Single cohort study of the effect of low dose naltrexone on the evolution of immunological, virological and clinical state of HIV+ adults in Mali. Journal of AIDS and HIV Research Vol. 3(10), pp. 180-188, October 2011
http://academicjournals.org/article/article1379515152_Traore%20et%20al%20(1).pdf (http://academicjournals.org/article/article1379515152_Traore%20et%20al%20(1).pdf)

LDN alone is not advisable for HIV but combined with HAART seems to be beneficial for CD4 counts and percentage.

I got interested in LDN since I get red patches on my face when I eat fast carbohydrates. The red patches started when I was in the AIDS zone and match the symptoms of psoriasis flaring up. Some people got cured from psoriasis by using LDN for 6+ months. I haven't started taking it but am considering it.