48 million viral load during acute hiv with fever and moderate flu like illness

[Tonny2]

Good evening and greetings to everyone here...
Wishes for happy weekend

         ojo.         Hello there!…same to you…hugs

[gpapadop91]

Hi guys.
Haven't been here for a long time!!!

What if crazy Putin starts a 3ww?

Will we run out of meds?
😳😳😳

[gpapadop91]

Good morning guys how are you??
A long time to write and hear from you.
I'm having 3rd time a bronchitis and cold within a 6 month period.
My son had pulmonary upper respiratory flu for 2-3 weeks so when he became better I put out masks because I felt I'm ok, I'm strong , so I got it 😜😂
And I couldn't sleep more from cough and woke up to boil a tea/camomile and thought let's see how is everyone...
Hugs brothwrs
Anyways how is everyone?

[gpapadop91]

Almost two months and didn’t hear news from any of you… hey give me signs anything for everyone is fine…
🙏🏽💪🏽

[Jim Allen]

Sorry to hear about bronchitis and I hope you and your son are feeling better.

Almost two months and didn’t hear news from any of you… hey give me signs anything for everyone is fine…
🙏🏽💪🏽

No news. Working, been sick (am sick), been busy these last few weeks.

You are welcome to keep everything in one thread but you might want to consider opening up new threads if it's a new topic or an off-topic thread if it's not related to HIV to get more engagement.  Just a thought

[leatherman]

I'm having 3rd time a bronchitis and cold within a 6 month period.
My son had pulmonary upper respiratory flu for 2-3 weeks

ugh. sorry to hear about all the illnesses. hope everyone gets well soon!

any of our sneezing, congestion, and watery eyes right now is from pollen. I miss living in Ohio sometimes (I even miss the snow.......sometimes) because the cold kills a lot of bugs and Spring is fast and not so potent. Here in the Carolinas, everywhere is coated in a yellow film of pine pollen and it won't be long until I need to swim in OFF mosquito spray or risk being eaten alive.

been sick (am sick)

yuck. all you people should learn to avoid germs better. 
feel better soon too!

[Jim Allen]

yuck. all you people should learn to avoid germs better. 
feel better soon too!

 

Ah yeah, antibiotics and bed-rest for the week.

[gpapadop91]

Hi guys .. sorry to bother you again.

Jim get well soon my friend ...

Please 🙏🏽 help I think it's seroconversion related .
I was found two days ago with d dimer level of 1,25 with cut off limit of 0,5

I am searching and seeing is possible after seroconversion the coagulation.

Do you mind any cases with the new treatments?

[Jim Allen]

D-Dimer test.

Presume it was for a reason, the cough prehaps. Anyhow, when are you following up with your doctor or have you already and what did they say.

[gpapadop91]

Hey there thanks for asking ,
Also on Friday I was found with

4400 WBC of 29% lymphocytes
CRP 11 with cut off 5 (chronic inflammation or maybe can this explainsned by the bronchitis I had last week?)
D dimer 1,3

.....

I talked with my hiv specialist doctor
He told me not panic and follow those doctors recommendations about checking repairatory blooding scintigraphy, .

Then searching the net I also saw that ddimer as well as Crp is used as biomarkers of measuring the inflammation...

We will see
Of course I will follow up with anything new and let you all know.

Anyways I really feel well...
I just had started overdoing with bad eating habits so last two weeks started again a diet and I'm in losing extra pounds mode

Kisses and hugs to all of you guys.

[Jim Allen]

Glad to hear you feel well.

Bronchitis is caused by a virus, like the common cold or flu or a bacterial infection resulting in inflammation. So sounds like they checked for a colt following your recent illness and coughing, had a positive indicator and are now going to investigate further.

I'm sure they can explain this more when you talk to them next, but do keep working with your doctors, try to relax and keep in mind that not everything is HIV related and you will get common illnesses from time to time just like everyone else in life.
 

[gpapadop91]

Μy friends hellooo
Can I ask you something please ?
The last month , I have between hair and eyebrow a redness on my skin about a coins surface in size, I think it's because of inflammation because in my recent blood tests (not the regular 6months tests which I will have it next week) I was found with CRP 12 !!!
Is it common such a big number while on art?
I confess last month I ate pizzas , chocolates , sweets , ice creams , all known to increase inflammation....
It's so red I can show you pictures today after all day yesterday hydrating this place ....
Don't tell me to relax , how can I relax , being positive with 12 CRP , with 50 millions initial VL , with one functional working kidney ....
Anyways , everything as info from your experience is welcome my bros...

[Jim Allen]

Stop eating crap, it's bad for you regardless of your HIV status.

The rest are all either irrelevant or things to discuss with your doctor although considering you were recently sick some inflammation would be expected but the results or potential causes need to be discussed with your doctor. Coin sized surface issues could be a number of things that again you would need to talk to your doctor about.

[gpapadop91]

Hey Jim thanks , really thank you.
I really stopped it.
I will follow very strict eating habits onwards.
Yesterday morning I ate 3 chocolwaffles and two chocolate balls with coconut pieces
Day before I had eaten chocolate cake with liquid chocolate inside and two I've cream balls
Also dried fries ... Oufff...

Anyways , a crp of 11,5-12 is it too much? Cardio doctor told me nothing to worry about its usual for many people...

In a month I will try to write here I didn't eat crap at all.
Boiled only

Any tips please for avoiding inflammation?

But please , understand me , how shouldn't I get stressed with such a picture of coin sized inflamed skin? 
By talking number of things , can I exclude cancer. ?

[gpapadop91]

How to send a photo as attachment here?

[Jim Allen]

But please , understand me , how shouldn't I get stressed with such a picture of coin sized inflamed skin?

No need to get stressed. It could simply be ringworm or something innocent that needs a cream but the only way to know is to see your GP.

You are going to have common heath issues in life just like everyone else. Get used to it as the only cure is being dead.

Anyways , a crp of 11,5-12 is it too much? Cardio doctor told me nothing to worry about its usual for many people...

Sounds like you have the answer.

[gpapadop91]

Οnly cure is dead 🤣😂😇🤣😂🤣😂🤣🤣🤣🤣 a
Thanks for this ☺️
Haha
Is everything fine in your lives?

What else? How is weather there?? ,🙏🏽🌺💪🏽 Good afternoon
And don't forget me , send me sometimes when you can please , all of you.

Bye guys

[Jim Allen]

What else? How is weather there?? ,🙏🏽🌺💪🏽 Good afternoon
And don't forget me , send me sometimes when you can please , all of you.

Bye guys

Grey and wet, it's Ireland. Anyhow, everything is fine here.

How to send a photo as attachment here?

https://forums.poz.com/index.php?topic=72951.msg761470#msg761470

[gpapadop91]

Thanks Jim , 2 days to have my 10 month tests , a bit stressed... Will inform you
Hoping Isentresss and Descovy out in deep sleep mode this fucking retrovirus
And also gained some 30-50 more cd4s than last October

Jesus 🙏🏽🙏🏽🙏🏽

[Jim Allen]

Thanks Jim , 2 days to have my 10 month tests , a bit stressed... Will inform you
Hoping Isentresss and Descovy out in deep sleep mode this fucking retrovirus
And also gained some 30-50 more cd4s than last October

Jesus 🙏🏽🙏🏽🙏🏽

No need to stress, it will be fine, keep us posted.

[gpapadop91]

Helloooo dears
How are you I wish you all have good lives ,,,
I want to share with you a tip that my soul doctor gave me today ,,, when I'm feeling bad or stressful I should be compared to poorer people who are jobless or have bad health issues so we can feel relaxed and stress free ,,, I can catch my self that it works for me at least ...

Unfortunately I missed my scheduled lab tests because I was delayed in my appointment
So they gave me a new date for 30 of May
I hope 🤞 we wil be fine ...
Kisses and hugs 🤗
Please keep posting here , I need to feel all of your presence here as often as you can leave a comment or a greeting guys

Bb

[Tonny2]

          ojo.       Hi!, don’t get me wrong but, I’m happy not “seeing you” around here that often, it tells me you are taking control of your life again, good for you!!

     ojo

https://youtu.be/UZVyzCwGVyE

I hope you can watch this video, it’s in Spanish but I think but just watching it you, all of us, get the message. There are people where are in worst situation than us and still move on with their lives…hugs


@jim moderator, if the video isn’t available to watched, maybe I did something wrong, could you help me?, thx

[daveR]

Helloooo dears
How are you I wish you all have good lives ,,,
I want to share with you a tip that my soul doctor gave me today ,,, when I'm feeling bad or stressful I should be compared to poorer people who are jobless or have bad health issues so we can feel relaxed and stress free ,,, I can catch my self that it works for me at least ...

Unfortunately I missed my scheduled lab tests because I was delayed in my appointment
So they gave me a new date for 30 of May
I hope 🤞 we wil be fine ...
Kisses and hugs 🤗
Please keep posting here , I need to feel all of your presence here as often as you can leave a comment or a greeting guys

Bb

Good to hear you are doing OK. The tip you shared is a good one. A few pages back on your epic thread I mentioned mindfulness practice. I find it useful, an app I use iw Waking Up by Sam Harris. It has guided meditations and also a theory section with discussions from himself and various people. In one of those lessons he recommends people to think of the worst thing that hasn't happened to them yet, living in a war zone, fatal diagnosis, and then imagine what the people who suffer from these problems would give to swap places with you. It really puts our positions into perspective when you realise just how lucky we are compared to others if HIV is our only issue.

Dave

[leatherman]

when I'm feeling bad or stressful I should be compared to poorer people who are jobless or have bad health

I have a similar philosophy - but the comparison is to events in my own life.

For a long time, the worst day in my life was when I suddenly had to leave my out-of-state college mid-year to move back home. On my bad days, I would say that at least it wasn't as bad as "that" day.

But then my first long term partner died, well, that day became the new measure of how bad the worst day was.

When my second partner was in the hospital, I got through a LOT of bad days because none of those days were as bad as the day my first partner died. Well, until my second partner died. Certainly now, there is absolutely nothing that could be as bad, no matter how bad things might get, than the day I had to keep living while not 1 but 2 partners were dead.

of course, right now I am risking having even a worse "worst day", but as of today, I'm happily still with my 3rd long term partner. Who knows? with some luck, maybe my husband will outlive me and I will never have experience anything worse than the day 2 partners were dead.

So that's how I survive the really bad days, by realizing that no matter how bad it is that day, it isn't as bad as my worst day.

To get through every day though, having been hospitalized with AIDS a few times, I just remember my motto: Any day I'm not in the hospital, no matter how bad, is still a GREAT day. and if you don't believe that, all I can say is try not dying in a hospital with a week , and then let's talk. At that point, I'm sure we'll both agree that not being in the hospital is awesome!

[gpapadop91]

Ηello guys good evening
How is everyone doing? How are your lifes?

I didn't post for a long time because I tried to follow your advices and it's true I started studying for exams for improving my position in my work.
Also I fixed many problems in my home and worked a lot and drank some more drinks and coffee ,,, you know it's summer and try to enjoy my last summer's 🤣😂🤣
Anyways , despite the fact that I have some good news I have some things that also worry me,

My last lab tests showed undetectable again.
And also 540 cd4 ☺️ I'm so happy and grateful to all you who supported me in my first month's when I was totally lost, sad and in deep depression....
All my rest tests were quite within limits ..
I only have a bit raised blood pressure of 8-12,5 ... Maybe due to the integrate ralltegravir.
However I'm happy I was able to recover even to the lowest limit of a healthy immune system above 500 cd4s

However I have developed on my skin some hemangiomas 2-3 already since May ...in various places of my skin , belly, face , small like 1-2mm^2 ... Also I read that the damage of the virus to the skin's cd4s is never cured and recovered again after initial infection, so I'm a bit of worrying about these hemangiomas because I read on the net that hemangiomas are over growing small and tiny
vessels  cells , something like multiple and fast cell growth as it's cancer but benign tumors and also these type of tumors are also developed inside the liver which is also stressed from the art therapy.

Does anyone have similar issues or knowledge?
Anyways , how are you??
What bout your summers? We had a sudden and strong rain today .. but I hope I can go to my village next week so I can enjoy my last swimming sets before autumn comes strongly 🙂
I will be more than glad to hear good news from all of you ...

🤗🤗🤗

[Jim Allen]

Sounds like you are doing great, stop stressing and reading rubbish online.

What bout your summers?

Good but glad the kids went back to school this morning 🤣

[leatherman]

My last lab tests showed undetectable again
....
However I'm happy I was able to recover even to the lowest limit of a healthy immune system above 500 cd4s

that's great you're still UD. Don't be surprised if that stays that way from now on
of course, that's as long as you remember those daily meds.

don't overthink your cd4s. Those things can change by 100 pts in a day, so the test result is just a snapshot of your cd4 count when your blood was drawn. Also, the cd4 test results are just a count of cd4s. there's no way to actually know how strong those cd4 cells are. Plenty of people living with a count less than 500 have zero health issues. As long as you keep HIV in check (i.e. undetectable), any illness you get will most likely not be HIV-related but simply the illnesses or diseases you might have gotten if you hadn't acquired HIV.

Because of how sick I was when diagnosed, plus the less effective meds in the 90s, it took me about 28 years to reach 500. Yet in the last 24 years since I was last in a hospital with AIDS-related pneumonia, I've really never been sick, not even with a cold. My little ol' 250-350 t-cells must be really strong and I have never even cared if I reached 500.

really the only reason your cd4 count should matter is if it goes below 200 because then you would be more susceptible to an HIV-related disease. although even a number that low is still not a guarantee that you would get one of those illnesses; but just that it's much much more likely.

What bout your summers? We had a sudden and strong rain today .. but I hope I can go to my village next week so I can enjoy my last swimming sets before autumn comes strongly

ugh. It never rains at my house here in South Carolina. Oh, it rains alllll around us but rarely does my lawn get more than a short sprinkle. I have an 18ft above ground pool and that where I spend a lot of afternoons. Sadly, as Summer is winding down, I'm afraid next week's low temperatures in the low 60s will get around to making the water too cold to get into for much longer. But I just came in from several hours (and several beers) floating around the pool, so Summer is still all good today for me. 

[gpapadop91]

Sounds like you are doing great, stop stressing and reading rubbish online.

Good but glad the kids went back to school this morning 🤣

Hellloooo Jim how are you
Good evening all of you 😘😘
I'm studying hard this period for university and I have forgotten a bit about hiv

However last week I was checking news and you know when opened the chrome it recommends some news that maybe interesting to you. And guess what , destiny .. hehe it showed me an article about trogarzo and multi drug resistance and heavily experienced patients ...
So tonight I saw this in my dreams that my GOD BLESSED PILLS stopped working effectively lately so I will need another form or maybe there was not enough...

So please 🤠
Tell me how easily is to develop a drug resistance to good pills of you take it normally and don't miss doses ??

The high initial viral load is a possible key factor tor a predictor that plays a key role to develop key resistance soon???

🙏🏽🙏🏽🙏🏽

[gpapadop91]

I also thought a bit more about this because also letterman told me it's good that I still remain ud
Isn't it granted that someone stays undetectable while on consistent treatment??
I had believed that since I'm taking my pills and I'm already ud since first month , it means for many years I will be UD and don't even need to think about my status again 😱😱😱

[gpapadop91]

I have an 18ft above ground pool and that where I spend a lot of afternoons.

Hey Leathterman how are you?? Happy autumn man
I didn't understand what 18sq meters or sorry square feet pool  you mean?? Above ground , meaning those which are temporarily installed and not permanently and built inside the ground? Anyways pools are so nice to take your breakfast 🙏🏽🥰

[gpapadop91]

How do I know if I have drug resistance?
A viral load test often gives the first indication of drug resistance. If your HIV RNA level does not drop soon after starting therapy, or if it starts going up while on treatment, this may be due to resistance. On the other hand, if your viral load is undetectable, that means your meds are doing their job unhampered by resistance. A rising CD4 count is another, usually later, sign that your treatment may not be working properly.

A rising CD4 count is another, usually later, sign that your treatment may not be working properly.


A rising?? Why? Maybe meaning a falling cd4 count??

https://www.poz.com/basics/hiv-basics/hiv-drug-resistance

I hope my 48 millions viral load isn't a predictive factor for developing resistanse.
I am. So happy and feel blessed that I have 16months UD and started thinking that maybe I will have this for decades .. these meds I feel are my GOD ...

SOMETHING more...
Sometimes I am drinking bicarbonate soda , eating onions and garlic.
I think I read somewhere that soda and garlics interfere with hiv medications, and maybe inactivate their best functionality..
How can I know what to eat and not to eat or drink to make it more difficult for virus to avoid drugs

Please 🙏🏽 some help
Opinions??

[Jim Allen]

Hellloooo Jim how are you
Good evening all of you 😘😘
I'm studying hard this period for university and I have forgotten a bit about hiv

Glad to hear that you are living your life instead of focusing on HIV. 

How are the studies going and how are you feeling?

However last week I was checking news and you know when opened the chrome it recommends some news that maybe interesting to you. And guess what , destiny .. hehe it showed me an article about trogarzo and multi drug resistance and heavily experienced patients ...
So tonight I saw this in my dreams that my GOD BLESSED PILLS stopped working effectively lately so I will need another form or maybe there was not enough...

So please 🤠
Tell me how easily is to develop a drug resistance to good pills of you take it normally and don't miss doses ??

Trogarzo was first approved in 2018, it's not new but its a treatment option for those with multidrug-resistant HIV.  https://forums.poz.com/index.php?topic=71116.msg

You don't have multidrug-resistant HIV and are extremely unlikely ever to develop multidrug-resistant HIV that would require any type of "salvage therapy" options unless you mess up with your current meds and then the next few combinations after that.

So don't. Take your meds.

The high initial viral load is a possible key factor tor a predictor that plays a key role to develop key resistance soon???

🙏🏽🙏🏽🙏🏽

Short answer, no.

Were not going back to you thinking your initial VL means doom and gloom are we?

Isn't it granted that someone stays undetectable while on consistent treatment??

If you have maintained a suppressed viral load for six months it means the meds are working and if you keep taking your meds correctly the viral load will remain suppressed. There are six monthly check-ups as well to make sure we're still on track.

It's not something picked out of thin air, there are 30+ years worth of treating people to back this up not to mention 23 years' worth of TaSP studies.

How do I know if I have drug resistance?

Usually, you can test for resistance this is often done before starting treatment, and if you don't and start treatment and are unable to maintain a suppressed viral load it's a potential sign and then you will switch treatments.

https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-arv/drug-resistance-testing

A rising CD4 count is another, usually later, sign that your treatment may not be working properly.


A rising?? Why? Maybe meaning a falling cd4 count??

https://www.poz.com/basics/hiv-basics/hiv-drug-resistance

Okay, you are stressing I feel about this, and there is no reason. However, I must admit this needs better context to avoid giving the wrong message, and I will provide feedback to POZ.com today.

The average range for CD4% in the HIV-negative population is anywhere from about 25% to 65%. This is the "normal" range.

I am writing this with you and those in mind that had very low initial CD4 counts; So with HIV treatment and once the meds started to suppress the virus, CD4 Recovery is desired and to a certain extent expected. Although, the context is this does not always happen or it can be slow progress taking years. Anyhow the increase in CD4 is because the immune system no longer has to fight a losing battle, and the immune system can start to recover, for lack of a better phrase.

This expected or desirable increase in CD4/CD4% isn't a sign of resistance or concern.

https://pubmed.ncbi.nlm.nih.gov/27650226/
https://www.aidsmap.com/about-hiv/cd4-cell-counts
https://aidsrestherapy.biomedcentral.com/articles/10.1186/1742-6405-8-2

Tell me how easily is to develop a drug resistance to good pills of you take it normally and don't miss doses ??

Not.

I hope my 48 millions viral load isn't a predictive factor for developing resistanse.
I am. So happy and feel blessed that I have 16months UD and started thinking that maybe I will have this for decades .. these meds I feel are my GOD ...

There it is. UD for 16 months, the meds are clearly doing their job and don't have any resistance issues.

it means for many years I will be UD and don't even need to think about my status again 😱😱😱

Yup, just keep taking your meds.

Sometimes I am drinking bicarbonate soda , eating onions and garlic.
I think I read somewhere that soda and garlics interfere with hiv medications, and maybe inactivate their best functionality..

Garlic ... you don't mean that recent publication on supplements in extremely high concentrations and the HIV drug saquinavir do you? You are not taking saquinavir are you or Garlic supplements? I though had switched to Isentress (raltegravir) + Descovy (emtricitabine / tenofovir alafenamide)?

Look, having a bit of garlic in your food from time to time or some onions on your burger isn't going to stop your meds from working or cause an issue. You should look out and inform your pharmacist about any additional medication you take or supplements to check for interactions. Supplements can be an issue for several reasons, including the high concentrations they contain.

I also always check the drugs.com interaction checker next to talking to my pharmacist. You can also check the package insert for the HIV drugs you take and it will list the drugs and supplements etc that can or could interact with the specific HIV meds you are taking.

[Jim Allen]

Question and don't answer it if you don't want to share, but what are you studying?

Forgive me if you already mentioned it and I missed it or forgot.

[gpapadop91]

Glad  hear that you are living your life instead of focusing on HIV. 

How are the studies going and how are you feeling?

Feeling fine , I unfortunately thought (after my very good June's results of 540cd4 and 3rd continuous time undetectable ) and taking into account all your life saving,mentally, comments and opinions and experience, that I would be forever undetectable and love even without aids till my 70s

I can see my pills were amazing, killing 48 millions per mm3 in one month and maybe less .. however maybe because im doing sth stupid or maybe not ( I never missed a doss , but many days due to tough schedule I managed to take my pills after 25-27 hrs and not as perfectly as 24 hrs and then I continued this schedule every 24 hrs since then so I managed to save 6 pills since I started treatment. So since year has 365 I still open new bottles evey 10th of each month.
Is this really a non consistent adherence to treatment???

However , I am fine and if in December I will continue being UD I will start relaxing even more .

Also stressed because I want to pass this exams to demand better job position.

My wife told me to not get stressed and want more but I'm ambitious and want to forget about virus and I do many things to live as much as I can till death 😂😹

[gpapadop91]

Were not going back to you thinking your initial VL means doom and gloom are we?

Jim I'm sorry but really didn't understand exactly what do you mean .

If you have maintained a suppressed viral load for six months it means the meds are working and if you keep taking your meds correctly the viral load will remain suppressed. There are six monthly check-ups as well to make sure we're still on track.
It's not something picked out of thin air, there are 30+ years worth of treating people to back this up not to mention 23 years' worth of TaSP studies.

Also this I didn't get you . I had initial vl check up the first month . Then after three again UD and then after 7 because I lost a month's appointment. And now I have in 2 months from now.

Six monthly check ups can only be done to a private clinic. Would you recommend it to me or its still fine from my hospital to get this every six months tests

Also about if it's is granted that when you take consistently tour doses and don't miss them occasionally, isn't it sure that you will remain UD for let's say 20 years ??

[gpapadop91]

Although, the context is this does not always happen or it can be slow progress taking years. Anyhow the increase in CD4 is because the immune system no longer has to fight a losing battle, and the immune system can start to recover, for lack of a better phrase.

This expected or desirable increase in CD4/CD4% isn't a sign of resistance or concern.

https://pubmed.ncbi.nlm.nih.gov/27650226/
https://www.aidsmap.com/about-hiv/cd4-cell-counts
https://aidsrestherapy.biomedcentral.com/articles/10.1186/1742-6405-8-2

So I'm sorry but I didn't understand well . And I don't want to misunderstand and I won't read now because it will add stress to me.
Long story short
My 167 CDs going to 534 in one year and still undetectable, means something bad or pulls still continue working well ??

The total WBC is similar , when it was 167 I had 3kwbc
And when I had 276cd4s I had 4,5kwbc
 and when 534cd4s it was 5kwbc

Almost always lymphs are about 900-1800

So if you want and only if you have time please only, explain in more detail please the relation between resistance and rising cd4? Body understands will lose fight and so creates more cd4s?

Hmmm I'm sorry I feel stupid

[gpapadop91]

I didn't switch.
I started from beginning with Descovy and Isentress .
No problems to kidneys
Perfect liver and kidney functionality and also undetectable since start.

I adore them I adore scientists I love my doctor's and you all here who mentally supported me . I hope this crispr proved to be the functional cyre in December. Correct? When it will be 12 months for the first results about a rebound or not???

B.
Intake regularly supplements but it is vitd3 in. 1k form per day because I have black skin and cannot absorb sunlight enough to create sufficient d.
I hope it won't interact with DECIVY AND ISENTRESS

ALSO
I cook with garlic and curcumim enough, not daily but sure 5-10 per month and I can see my normal blood tests are better than before infected with d3 / garlic/ plant based diet

[gpapadop91]

Question and don't answer it if you don't want to share, but what are you studying?

Forgive me if you already mentioned it and I missed it or forgot.

Hey Jim my best friend , I say this because I really feel this 🙏🏽🤗

I will write you on pm or I will tell you. This year I wil come for sure to Dublin close to Xmas with my son 🤝🤝🤝🥰😚🌷😻🌹

[gpapadop91]

The results from Descovy and Isentress , are my psycho pharmacies meds

They made me forget hiv

I love them I love who created them
I love my docs

I still pray to work forever as long as I will live
Thanks God

[Jim Allen]

Jim I'm sorry but really didn't understand exactly what do you mean .

With that I mean that I hope that you are not slipping back into stressing over anything, hyper focusing on rather irrelevant things and thinking you will die soon.

Also this I didn't get you . I had initial vl check up the first month . Then after three again UD and then after 7 because I lost a month's appointment. And now I have in 2 months from now.

That's fine. 

When starting out it's common to have more frequent visits in the first few months and after that the recommendation for someone with stable and suppressed HIV is to have their viral load checked every six months. A month later or sooner isn't an issue, it's just a checkup.

I used to have mine every 2/3 months for years as they didn't trust me to take the meds correctly 

Feeling fine , I unfortunately thought (after my very good June's results of 540cd4 and 3rd continuous time undetectable ) and taking into account all your life saving,mentally, comments and opinions and experience, that I would be forever undetectable and love even without aids till my 70s

Glad you feel fine.

Keep taking your meds, look after yourself and attend your clinic visits, your well-controlled HIV isn't going to stop you from reaching your 80s+

I never missed a doss , but many days due to tough schedule I managed to take my pills after 25-27 hrs and not as perfectly as 24 hrs and then I continued this schedule every 24 hrs since then so I managed to save 6 pills since I started treatment. So since year has 365 I still open new bottles evey 10th of each month.
Is this really a non consistent adherence to treatment???

Glad to hear you never missed a day of your meds.

Every 25-27 hours for a few days over the year. So on those days, you took the meds 1-3 hours late if I understand you.

Look ideally you take the meds at the same time every day, which helps prevent you from forgetting them all altogether however, life happens and a few hours early or late isn't going to be an issue.

Perfect adherence is considered taking your meds 95%+ of the time on time. So even if you missed a few pills completely over a year it would still be perfect adherence (Not that I recommend skipping pills, don't) 

Personally, I aim to take my pills within a four-hour window per day. Things that can help are setting a reminder on your phone or picking a better time to take your meds.

You are not the first nor will you be the last person to ask about adherence and worry about a few hours.

Adherence
https://forums.poz.com/index.php?topic=73377.msg

https://forums.poz.com/index.php?topic=64111.msg

Adherence?
https://forums.poz.com/index.php?topic=71153.msg




https://www.aidsmap.com/about-hiv/adherence-hiv-treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943894/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839839/
https://journals.lww.com/jaids/Abstract/2019/11010/Antiretroviral_Adherence_Level_Necessary_for_HIV.3.aspx

Would you recommend it to me or its still fine from my hospital to get this every six months tests

The public is clinic is fine.

Also about if it's is granted that when you take consistently tour doses and don't miss them occasionally, isn't it sure that you will remain UD for let's say 20 years ??

Hmmm...Do I think that I will remain UD for 20 years if I take my meds correctly?
Yes, I take my meds and that's my expectation. I don't have any medical conditions that cause absorption issues and I check for interactions.









 

[leatherman]

So if you want and only if you have time please only, explain in more detail please the relation between resistance and rising cd4? Body understands will lose fight and so creates more cd4s?

resistance is what happens when the meds no longer work well against HIV. If this happens you will see your viral load start to go back up (with at least a few tests showing the result is climbing) and you would need to change medications. However, resistance only happens when you take your meds haphazardly. For example, if you take your meds 4 days in a row, then skip 2 days, then take them for 3 days and skip 1....etc. Taking the meds off and on like that can allow the amount of meds in your system to dip too low and HIV may "learn" to not be affected by those meds. However, this doesn't mean skipping meds one or two times would cause resistance. As long as you take your meds 95% of the time, the meds should continue to work well for you. In the past, resistance was a big issue but the meds these days are much better and, quite frankly, you have to be a terrible paitent barely taking your meds for resistance to be an issue.

here's some more information about resistance I have posted before:
https://forums.poz.com/index.php?topic=75522.msg775806#msg775806

My 167 CDs going to 534 in one year and still undetectable, means something bad or pulls still continue working well ??

Body understands will lose fight and so creates more cd4s? 

cd4s going from 167 to 534 in a year is incredibly good. You want to keep the HIV viral load undetectable (or at least <200) and you want your cd4 count to be >200. The normal range for cd4s is considered 400-1200. Your count of 534 is perfectly normal and if it increases more that is a very good thing as it means your immune system has recovered from the damage done by HIV.

Hmmm...Do I think that I will remain UD for 20 years if I take my meds correctly?
Yes, I take my meds and that's my expectation. I don't have any medical conditions that cause absorption issues and I check for interactions.

Yes! Me and a whole lot of friends have been on meds for 30+ years and are still doing fine. some of us have changed meds though, mainly as meds improved to reduce the amount of pills. I used to take 28 pills a day way back in 1992. Now I take 2 a day....and I've been undetectable for 20 years already and expecting that for another 40 years. 

[Jim Allen]

Hey Jim my best friend , I say this because I really feel this 🙏🏽🤗

I will write you on pm or I will tell you. This year I wil come for sure to Dublin close to Xmas with my son 🤝🤝🤝🥰😚🌷😻🌹

Sounds good.

[Jim Allen]

expecting that for another 40 years. 

 

Ill have a comment on this for our next virtual gathering.

[Tonny2]

           ojo.          @goaoadop91…glad to hear you are doing good but, I agree with Jim, I think you are worrying, again, for something that may never gappen to you, abd if it were to happen, you have lits of options to switch to, you have not history of resistance, do you?…worry until you have something that be worried about, not before because you will live with stress and you will be wasting  time, keep yourself busy and keep enjoying life as you have been doing for a while…it’s always good to hear from our members that they have learned to live with the virus and have gone back to live their lives fully. Just take your meds as prescribed and go back to live lufe because live is short with or without hiv…good luck



Ps I’m one of the “lucky” ones with a history of resistance, I have been taking my “salvage” treatment for 17 years abd I’m not worried about my treatment not working anymore.