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Author Topic: Celebrex with Tenofovir (TDF)  (Read 949 times)

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Offline Mindless

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  • Posts: 343
Celebrex with Tenofovir (TDF)
« on: December 11, 2019, 04:10:02 am »
Got a very bad backache few days ago and eventually decided to visit a specialist about it.

Got a bad news: dr suggested a X-ray and discovered I have a congenital spine defect that’s potentially quite dangerous, goes by the weird name of “lumbar spondylolisthesis”. Basically, from what I understood, part of a vertebra was not completely formed during pregnancy for some reason and now the bone stays dangerously “loose”. It may worsen over time (most likely with old age) depending on luck and lead to serious issues. Not much one can do except physiotherapy and strengthen abdominal muscles, surgery as last chance in case it gets bad.

Anyways, for now my situation seems to be manageable, even if I will probably go through recurrent episodes of backache over time. He suggested special physical exercises, physiotherapy and anti-inflammatory/painkillers for a week. Prescribed Celebrex and Neurotin for 1 week until next check. I run my usual medication interactions check and discovered Celebrex has a potential strong interaction with TDF (I take Complera). The warning is related to kidney function as both meds are potentially toxic for the kidneys. I recently discovered my eGFR has steadily decreased over the last 2.5 years (last figure was 77, was 96 and I’m 50 yo).

Not sure what to do given I’m supposed to take Celebrex for a few days: anyone has experienced with these drugs? I’m not seeking medical advice, just looking for someone’s else experiences to share. I will consult my HIV dr if necessary.


Offline bocker3

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  • You gotta enjoy life......
Re: Celebrex with Tenofovir (TDF)
« Reply #1 on: December 11, 2019, 06:41:20 am »
I was given short-term NSAIDs (diclofenac or nabumetone) to take for a chronic back issue a couple of times and am also on Descovy.  I was told it was fine for short periods (I will likely have recurrent episodes, unless i fully give up tennis -- which isn't in my current plan).
However -- every person's situation is different, so you should check with your pharmacist and/or doctor for guidance.


Offline Mindless

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  • Posts: 343
Re: Celebrex with Tenofovir (TDF)
« Reply #2 on: December 12, 2019, 10:12:33 am »
Thank you for the feedback Mike. I eventually decided to take it cause it’s only for a few days and low dosage (and the pain is not going away). Anyways, I will discuss with my hiv doc, since this may not be the last time I will need to take it.



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