User

Welcome, Guest. Please login or register.
April 19, 2024, 03:32:52 pm

Login with username, password and session length


Forums Index

Stats

Members
  • Total Members: 37644
  • Latest: Aman08
Stats
  • Total Posts: 773218
  • Total Topics: 66338
  • Online Today: 716
  • Online Ever: 5484
  • (June 18, 2021, 11:15:29 pm)
Users Online
Users: 2
Guests: 679
Total: 681

Search

Welcome


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Do I Have HIV?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.
« previous next »
Pages: [1]   Go Down

Author Topic: CoH and Sangamo to try again  (Read 4072 times)

0 Members and 1 Guest are viewing this topic.

Offline Hoyland

  • Member
  • Posts: 99
CoH and Sangamo to try again
« on: August 21, 2013, 12:13:29 am »
The City of Hope is applying to start a new Pl trial of the Sangamo Zinc Finger Nuclease HIV treatment. Here is the agenda item for next month's RAC meeting.

Quote
Discussion on Human Gene Transfer Protocol #1307-1240 titled: A
Phase I, Open-Label Study to Assess the Safety, Feasibility and
Engraftment of Zinc Finger Nucleases CCR5 Modified Autologous CD34+
Hematopoietic Stem/Progenitor Cells (Sb-728mr-Hspc) with Escalating
Doses Of Busulfan in HIV-1 (R5) Infected Subjects with Suboptimal CD4
Levels on Antiretroviral Therapy

PIs: Amrita Krishnan, M.D., City of Hope, Duarte, CA
John Zaia, M.D, City of Hope, Duarte, CA

If RAC recommend the trial goes ahead, then I think CoH will have to submit a new IND to the FDA before the trail can commence. It is possible that the trail could begin by the end of the year, if the FDA has no objections.

http://oba.od.nih.gov/oba/RAC/meetings/Sept2013/Sept_11-12_2013_agenda-Public_Draft.pdf
Logged

Offline geobee

  • Member
  • Posts: 376
Re: CoH and Sangamo to try again
« Reply #1 on: August 21, 2013, 09:53:15 am »
This is different.  It's stem cells.  Previous trials modified T-Cells.
Logged

Offline freewillie99

  • Member
  • Posts: 326
Re: CoH and Sangamo to try again
« Reply #2 on: August 21, 2013, 11:49:49 am »
Quote from: geobee on August 21, 2013, 09:53:15 am
This is different.  It's stem cells.  Previous trials modified T-Cells.

Large.
Logged
Beware Romanians bearing strange gifts
Pages: [1]   Go Up
« previous next »
 

Terms of Membership for these forums
 

© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.