POZ Community Forums
Meds, Mind, Body & Benefits => Research News & Studies => Topic started by: datdude on October 17, 2007, 07:35:55 pm
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Has anyone heard of an Asian Violet known as Viola Yedoensis it contains tiny protiens that appear to kill off infected cells
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If only....I would not be surprised that one day a cure or great treatment would be found in a plant, but I have not heard of this. I did a quick reserach and found this:
(http://www.news.com.au/story/0,23599,22480131-36398,00.html)
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Sydney, (ANI): Scientists from Australia, Europe and the US have found that a Chinese herb, which has been used to treat snakebites and boils for centuries, has the potential to fight HIV/AIDS. The researchers say that an Asian violet known as Viola Yedoensis contains tiny proteins that appear to kill off infected cells. Such anti-HIV and anti-bacterial qualities, say the researchers, make the plant a target for new drug therapies to treat the HIV virus. While presenting their findings at COMBIO 2007, a meeting of biochemistry and molecular biology specialists in Sydney, researchers at the University of Queensland said that the plant contains small proteins called cyclotides that might act as defensive agents.
The researchers say that an Asian violet known as Viola yedoensis contains tiny proteins that appear to kill off infected cells.The researchers tested the ability of the cyclotides by applying them to two sets of cells—one infected with HIV and the other virus-free. Their aim was to see how many of the cells infected with HIV were destroyed after the application of the cyclotides. "The results were encouraging. The actions of the cyclotides are yet not fully understood and the research is at a very early stage,” said new.com.au quoted Professor David Craik from the Institute for Molecular Bioscience at the University of Queensland as saying.
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Of interest is whether this Combio conference is bona-fide, or just a quack-fest...does not seem to be the latter, seems genuine, although more research is in order. J.
p.s. I found a website for the conference, it just has info from before it took place.... http://www.asbmb.org.au/combio2007/index.html . I'll keep looking.
p.p.s. Okay seems this conference is the real deal...not to say that this discovery will pan out- it's always possible, of course- but at least the conference is comprised of bona-fide scientists. I found another article, which is almost the same as above (http://www.news.com.au/mercury/story/0,22884,22480265-5006544,00.html), except it ends:
The research collaboration also involved the National Cancer Institute in the United States and the Division of Pharmacology at Uppsala University in Sweden.
It was presented at COMBIO 2007, a meeting of biochemistry and molecular biology specialists
So, we watch...
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http://scholar.google.com/scholar?q=Viola+Yedoensis&hl=en&lr=&btnG=Search
research from 1988 to 2001 to 2006 on this and hiv
the good thing now is with new tech perhaps the active ingredient is able to be found
Department of Chemistry, University of California, Davis 95616.
The dimethylsulfoxide extract of the Chinese medicinal herb Viola yedoensis demonstrates high inhibitory activity toward HIV-1 in vitro. The corresponding methanol extract also showed inhibitory activity but not as high as the dimethylsulfoxide extract. Anti-HIV activity in the extracts is accompanied by cytotoxicity, and we describe here the separation of the cytotoxic material from the active fraction. We also describe the procedure for isolation, purification, and separation of the active component from crude extracts of V. yedoensis as well as details of its activity against HIV-1. The UV-visible, infrared (IR) and proton nuclear magnetic resonance (NMR) data and certain other characteristics of the active compound are also presented. Initial chemical tests and the proton NMR and IR spectra indicate a high molecular weight sulphonated carbohydrate polymer, and chromatographic evidence suggests an MW between 10,000 and 15,000.
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Bimazek could you put that in English, I have no clue what any of that means.
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What Bimazek quoted is a study from 1988. I would discard it.
There are new studies from 2006 and 2007 that are more interesting.
Milker.
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Just what I have found on my side.
Not real scientific links, but the good news is that this flower is already commercialized as a tea (see note below).
(http://www.brisbanetimes.com.au/ffximage/2007/09/25/viola_lead.jpg)
Source: http://www.acupuncture.com/research/hiv2.htm
Clinical Observation on ZY-1 in Treating 52 HIV-Infected Patients
By Lu Weibo, Gu YH, Wang J, Xu X, Wang ZK, Shao J*, Mpemba N*, Mbena E*
Lu Weibo, Gu YH, Wang J, Xu X, Wang ZK, Shao J*, Mpemba N*, Mbena E*. China Academy of TCM, CHINA, *Muhimbili Medical Center, TANZANIA
Objective: To assess efficacy of ZY-1,a Chinese medicinal herbs recipe.
Methods: 52 HIV-infected patients (including 19 AC, 9 ARC, 24 AIDS). ZY-1 is a comp. Chinese herbal recipe, consisted of Astragalus membranaceus, Viola yedoensis etc, indicated for early and middle stage pts, taken 10g, 3/d. ELISA and/or WB were done, and lympho. subsets were measured before and after treatment. Fatigue, fever, cough, diarrhea, anorexia, lymphadenopathy, skin rash were displayed. T4CC was 246.21/mm3, T4/T8 was 0.43 in average.
Results: After treatment, most symptoms alleviated, immune function improved in 14 pts, unchanged in 16 pts, sum 30 pts (57.7%). Total eff. rate 51.9%. 1 pt showed seroreversion after taken 3 mths of ZY-1, whose immune function was high. SIV monkey model also showed better results with immune and pathol. improvements than that of AZT and NS control.
Conclusions: ZY-1 is effective both clinically, immunologically and serologically.
NOTE
Tokyo Violet Herb is the dried herb of Viola yedoensis Makino (Fam. Violaceae).
Can be bought on the internet.
Among others website:
http://www.mothernature.com/shop/detail.cfm/sku/29227
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I am from Ontario and the community is very optimistic about a vaccine being developed at the University of Western Ontario.
It's not very widespread, but the Body reports on it.
http://www.fyilondon.com/cgi-bin/publish.cgi?x=articles&p=194168&s=health
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I am from Ontario and the community is very optimistic about a vaccine being developed at the University of Western Ontario.
It's not very widespread, but the Body reports on it.
http://www.fyilondon.com/cgi-bin/publish.cgi?x=articles&p=194168&s=health
Yes Dr. Kang's vaccine, I too have great hopes for that one. I am anxiously awating for the trials to begin, let's see if in 2008.
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What Bimazek quoted is a study from 1988. I would discard it.
There are new studies from 2006 and 2007 that are more interesting.
Milker.
milker...
when i heard about this new thing it sounded great, i have even been carrying around the words
Viola yedoensis
on a piece of paper for a month trying to get time to go buy the stuff at a chinese herb store, i even went in a few places and one said i needed an Rx from a chinese doctor which is obviously a huge lie because it could open the chinese herb dr. to practicing medicine in usa without license ... correct
but anyway
i am very hopeful about this...
i was very very excited at first but then when i saw that it was first reported in 1988 then i was like oh well they knew and it wont help to take the herb much
but that is why i posted it that way
but the active ingredient with all the modern 3d molecular modelling could come up with some great thing based on this herb
so please dont jump on me
all i am saying is that it was reported along time ago...