Welcome, Guest. Please login or register.
October 02, 2022, 09:15:55 pm

Login with username, password and session length


Members
Stats
  • Total Posts: 766165
  • Total Topics: 65355
  • Online Today: 129
  • Online Ever: 5484
  • (June 18, 2021, 11:15:29 pm)
Users Online
Users: 1
Guests: 70
Total: 71

Welcome


Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Do I Have HIV?” posting guidelines. Click here for posting guidelines pertaining to all other POZ community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Maraviroc treatment  (Read 560 times)

0 Members and 1 Guest are viewing this topic.

Offline testii28

  • Member
  • Posts: 21
Maraviroc treatment
« on: July 11, 2022, 02:30:12 am »
A friend of a friend was treated with biktarvy and maraviroc in Germany. Now he is since almost 1,5 years virus free and don't have to take any medication. Why they don't offer this option also to us? Isn't it worth a try?

Offline daveR

  • Member
  • Posts: 258
Re: Maraviroc treatment
« Reply #1 on: July 11, 2022, 02:50:08 am »
I couldn't find anything documented about that on the internet. I would have expected one of the HIV sites to have heard of it. Can you please get some more details from your friend of a friend?  Dr's name, hospital name. Details of their stats, how long infected, viral load. How long they took the medication.
Let's be honest, if it was as simple as a couple of pills for a short while, we would all be doing it.

Offline testii28

  • Member
  • Posts: 21
Re: Maraviroc treatment
« Reply #2 on: July 11, 2022, 03:05:32 am »
I will try to get the information as soon as possible. They are offering in Germany even neutralizing antibodies treatment. If all is really true I will move back then for a while.
The are calling it "functional healing". The virus can come back in some cases after a few years but so what.  I think it is worth it.

« Last Edit: July 11, 2022, 03:25:55 am by testii28 »

Offline Jim Allen

  • Administrator
  • Member
  • Posts: 19,490
  • Twitter @JimAllenDublin
    • HIV Lessons
Re: Maraviroc treatment
« Reply #3 on: July 11, 2022, 04:28:50 am »
Hiya,

Not sure why your friend of a friend isn't taking their meds, However, they are not virus-free and Maraviroc (Selzentry) + Biktarvy certainly doesn't cure HIV functionally or otherwise.

It is well documented that with standard treatment alone, outliers have gone off treatment and maintained a suppressed viral load for months or sometimes years. Just an example, https://pubmed.ncbi.nlm.nih.gov/34117753/ & https://pubmed.ncbi.nlm.nih.gov/31225610/ or more extreme; https://www.poz.com/article/9yearold-child-born-hiv-spent-8-years-viral-remission
https://www.poz.com/article/mississippi-child-update-26958-2709

Maraviroc is an entry inhibitor and has been around for years, within the EU since 2007. In the past, just like many other HIV meds, it has been used in studies in combination with new novel treatments to study the possibilities of functional cures.

Maraviroc:
https://www.poz.com/drug/selzentry

In combination with bone marrow transplants: https://www.poz.com/article/man-hiv-longterm-viral-remission-intensified-treatment

Note they did rebound in 2021.

Lopez-Huertas MR, Gutierrez C, Madrid-Elena N, Hernandez-Novoa B, Olalla-Sierra J, Plana M, et al. Prolonged Administration of Maraviroc Reactivates Latent HIV In Vivo But it Does Not Prevent Antiretroviral-Free Viral Rebound.
https://pubmed.ncbi.nlm.nih.gov/33339855/


« Last Edit: July 11, 2022, 08:59:05 am by Jim Allen »
HIV 101 - Everything you need to know
HIV 101
Read more about Testing here:
HIV Testing
Read about Treatment-as-Prevention (TasP) here:
HIV TasP
You can read about HIV prevention here:
HIV prevention
Read about PEP and PrEP here
PEP and PrEP

 


Terms of Membership for these forums
 

© 2022 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.