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Main Forums => I Just Tested Poz => Topic started by: gpapadop91 on July 08, 2021, 04:11:54 pm

Title: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 08, 2021, 04:11:54 pm
Hey there.
I'm with you
Infected by a transgender while she came and a small drop fell into my eye. Reading and asking on some other forum here I was told because of air inactive hiv will not infect me.
So after 3 weeks , seroconversion illness.
Also diagnosed with  with past CMV illness with IgG antibodies.

Generally last 10 years I had small low white blood cell count

So when diagnosed I had 48millions viral load VL
Also 170 cd4
Cd4/cd8 ratio of = 0.4

My doctor does not talk to me too much. He tells me I'm anxious. This is not reason to not tell me what, how, etc....
Anyways

I started ART at 40 days after infection.
Today I gave sample to measure again my cd4 and viral load after a month of initiation of art.

Also Yesterday I had vaccination for covid.
I also read that vaccinations may increase viral load.
Also increased viral load is factor of drug resistance.
Doctor also told me it's very huge number my viral load but it was peak due to peak acute phase also my cd4 was low because generally I had low WBC so it's normal in acute phase to see a dive in cd4 number

I read everywhere and I think these.:
Low cd4/cd8 means difficult to recover cd4s
High viral load (mine , although in acute phase was huge HUGE) treated or untreated progress to AIDS fast.

Finally my questions are.

Did you see again so high viral load?
Was mistake to risk having covid vaccination now that viral load is not known if suppressed well or not???
Should my doctor tell me?
Should I expect to live 3-5 years or more with so huge VL???

Please relief my pain in soul. I will not suicide, so don't tell me lies!!! I just want to know to take care better of my health.

Need your understanding and support my brothers.
Should Expect to live more years because new drugs are highly active???

I am 35
Thanks
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 08, 2021, 04:24:39 pm
Hiya,

Sorry to hear about the diagnosis and the low CD4 count & CMV.

Understand you started HIV treatment some 40 days ago, and today they took blood to see if it's begun to suppress the virus.  Have you been provided antibiotics considering the low CD4?

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1) Did you see again so high viral load?
2) Was mistake to risk having covid vaccination now that viral load is not known if suppressed well or not???
3) Should my doctor tell me?
4) Should I expect to live 3-5 years or more with so huge VL???

1) VL in the millions sure, mine was at some stage.
2) No
3) They should recommend the vaccine
4) You could live for another 50 or 60 years, your 35 now. Depends on what happens in your life but don't smoke, eat healthly and exercise if you want to live healthier and perhaps longer, and considering you are living with HIV take your meds.

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I also read that vaccinations may increase viral load.
Also increased viral load is factor of drug resistance.

Resitance does not happen from just a single blip in viral load when starting out or ever to be honest and you are on treatment now.

Quote
Doctor also told me it's very huge number my viral load but it was peak due to peak acute phase also my cd4 was low because generally I had low WBC so it's normal in acute phase to see a dive in cd4 number

That's a presumption, could be late phase, there is no way to really tell from those labs.

Quote
Reading and asking on some other forum here I was told because of air inactive hiv will not infect me.

Not sure what other forum you mean, but if they told you that it's part of the reason why it's not an HIV risk.

You did not acquire HIV this way, let that be clear but were not going to focus on that and we don't care how you actually acquired HIV, you are here now and we will support you.

Best, Jim



Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 08, 2021, 04:43:17 pm
Jim thanks for your answers.
I really appreciate this.

Let me be more clear!!

I was negative always. Until April with tests.
Even when diagnosed , I was negative in antibody tests.

I started ART 40days after infection.

Also it was very acute phase , not long stage.

Reading about this other forum , I don't have reason to tell lies.
My doctor told me a person like me with such high viral load can infect anyone with VL 48 millions. Not 4.8 , but 48 millions. I could infect anyone with a drop into eye.

All condoms checked after , they were intact.

Please tell the world , even Dr Hook told this. Semen in eye should prescribed Pep.
But asking in the forum , users told me no need.

However a high viral load as hers infected me because I also didn't clean my eye immediately and it was irritated.

Anyways. This is past now.

Jim or any other please here ....
Did you ever see again 48-49 millions????
Will I suppress it???


I read this in a study of 2018.

Treated or untreated high viral load (100.000-500.000) indicates faster illness progression and/or related illnesses and cancers leading to cormobidities or death.

I'm 35.
Should I expect to plan my death from now ? I mean to give everything to my child , to prepare my wife and my parents according to my HUGE viral load 49 millions???

2. Does huge VL means my body doesn't fight well so , strong cancers will come fast and soon????

Thanks in Advance!!!

My only hope is the new broadly neutralising antibodies or gene therapies or mran hiv vaccines , if I don't have until this time any bad cancer!!!!
Should we expect a cure until 2025?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 08, 2021, 05:07:15 pm
Quote
I was negative always. Until April with tests.
Even when diagnosed , I was negative in antibody tests.

Let me be very clear and final on this  ;)

You acquired HIV most likely after Jan/Feb then, but you did not acquire HIV the way you think. (Edit to add, another reason why I say this is I have now checked and read your post from back in May on the other website!)

Now move on because we're not going to focus on that and you don't want me to start poking holes in your story as there are already. To be clear we don't care how you actually acquired HIV, you are here now and we will support you.


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Will I suppress it???

Yes, with treatment.

I am sure your VL will already be lower when you get the latest results in and give it time to work.
What ART are you taking BTW?

Quote
Should I expect to plan my death from now ? I mean to give everything to my child , to prepare my wife and my parents according to my HUGE viral load 49 millions???

2. Does huge VL means my body doesn't fight well so , strong cancers will come fast and soon????

No, you don't have to start planning and preparing your wife & child for your death soon because of your HIV status, and there are plenty of members here with far worse results than your who are doing just fine today.

The low CD4 counts mean you are at an increased risk for certain OI's and cancer, however, once the viral load reduces and the body can "heal" the CD4 counts should also increase again with time. Once the VL is suppressed and it will be the CD4 count become somewhat less relevant. That said plenty of people still have low CD4 counts and are perfectly healthy.

As a group we are prone to certain conditions more frequently or sooner in life, that does not mean it will be an issue for you and you will see your doctor or clinic during check-ups to monitor things and treat any issue early.

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Should we expect a cure until 2025?

Well, you are going to see very different options on the "cure" topic, just search the forums, 100's of threads going back since this version started in 2006.

Now, going back decades there was always some new promise or cure around the corner or new breakthrough that did not work out. My point of view is if I was a mouse or a petri-dish I would have had 100's of cures by now from the past 20 years, sadly although it is scientifically very interesting it's never resulted in something that could be rolled out to the community living with HIV.

My thoughts are given how HIV works and even recently was found in various new cells types that we are only just learning about a cure will not happen within my lifetime, although better treatments and perhaps long term suppression would I feel be possible.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 08, 2021, 05:21:22 pm
Thanks for your support...don't lose hope...
Your re young enough. We will have it
Of course not soon.
But mayybe In 5-10-15 years if I don't have cancer until then....

I started Descovy + Isentress because I have 1 and 25% kidneys , working 90% and 10%.


I hope Isentress , an integrase inhibitor will do the job.

But you really feel I will be undetectable even with started 50 millions????

Also, should I be optimistic I will not have cancer soon???
I mean next 5-10 years???
Should I expect to enjoy a bit more my son???

What about vaccinations? Can I have an hpv vaccination?

Last question!
So you think even if you think that I had from February (I know my exposure it was 28April) , that it progresed to AIDS late stage In 2-3 months??
So again same question...
Should I expect to live 2-3 years or 20-30????
Really , honestly
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 08, 2021, 05:40:03 pm
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But you really feel I will be undetectable even with started 50 millions????

Yeah, sure. Keep taking the meds and within 6 months it should at least be 90%+ reduced and if not there are other treatment options.

Now you will see posts from other people reaching suppressed, UD, undetectable with a few weeks and others take a year.  Don't let it get to you as it's not a race.

Now asides from keeping HIV suppressed so it can't do unchallenged damage to you, the other good thing is once you have achieved an undetectable viral load* for at least 6 months, you can't sexually pass on HIV to your wife & other partners.

This is also known as Undetectable = Untransmittable (U=U)
* https://forums.poz.com/index.php?topic=71864.0

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Also, should I be optimistic I will not have cancer soon???

I don't know what your risks are for cancer. If your only concern is just HIV then I see no reason to start expecting cancer soon.

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Should I expect to enjoy a bit more my son???

Like I said you could live for the next 50-60 years, you could also be run over by a bus tomorrow. HIV is not an automatic death sentence or short life span, treat it and look after yourself to live a healthier and longer life if you want.

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What about vaccinations? Can I have an hpv vaccination?

HPV depends, certain nations still limit it to lower ages, but talk to your doctor. Vaccines, in general, there are plenty of vaccines recommended. Your doctor would not do them all at once mind you and some of them will wait for your CD4 counts to be higher.

https://www.cdc.gov/vaccines/adults/rec-vac/health-conditions/hiv.html
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 08, 2021, 06:27:16 pm
Jim , and all here.
You are my brothers.
I am a member of you.
Jim you relaxed me a lot.
My doctor answered me now.
IT WILL NOT PROGRESS TO AIDS. YOU STARTED TREATMENT DURING ACUTE INFECTION WHICH IS THE BEST SCENARIO"

In 2 weeks I have meeting with professor of hematology in university of doctors school. I will ask everything why I have so low WBC and I will provide all information here.

Greetings
Good night

Also Jim , when time , please answer about Oxfords new trial!
What do you see?
mRNAs?

God bless you all.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 08, 2021, 06:36:58 pm
IT WILL NOT PROGRESS TO AIDS.

Depending on your definition it's already late-stage or AIDS but with treatment, the viral load will suppress. Relax and your WBC could have been low from the HIV infection or any number of things, give your immune system time and keep working with your doctor.

Quote
please answer about Oxfords new trial!
What do you see?
mRNAs?

That's HIV-CORE 0052, HIVconsvX vaccine. My thoughts, well if I was a petri-dish I would be ecstatic, but until it gets to phase 3 I no longer even get interested in these things.

https://forums.poz.com/index.php?topic=75397.msg
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on July 09, 2021, 06:58:32 am
a small personal story to support what Jim has told you:
in the late 90s when, unlike today, there were few meds and almost all had side effects, I was hospitalized with AIDS at age 36 with a viral load in the millions and only 5 cd4s. It's been 37 years now since I was infected (and 29 yrs on meds), I'm getting close to turning 60,  I've been undetectable for decades, my cd4s are near 500, and I could not be happier or healthier.....all thanks to staying adherent to HIV medications. No cancers, no issues, and if my Grandmother is any example as she is within a month of turning 104, I'm expecting to not only live these 25 yrs since that hospitalization but I'm expecting I may have another 40 years on top of that. :)

Oxfords new trial
one last word of advice: don't get hung up on wishing for a "cure". Today's meds are quick and easy to take with few to no side effects and very effective at suppressing HIV. I take a few pills every morning and get on with my life not thinking about HIV these days....and you'll get to that point too in the not too distant future if you stay adherent to daily meds.

As far as the Oxford trial, the med they are currently researching is designed as a vaccine ... a preventative. Unfortunately, we are already HIV positive so a vaccine might not do anything for us. Of course, these vaccines are also considered for whether they could be a "therapeutic vaccine", which means it might suppress HIV for the long-term (months to years).

Once infected and then treated, HIV decreases but doesn't completely go away. Tiny bits remain in our bodies but dormant. That's why we take meds daily - to suppress any of this remaining HIV that becomes active. Until a complete cure is created, HIV positive people will need to remain on some type of medications, whether it be daily or (coming soon) a long term injection that lasts for months at a time.

Even though I tested positive a long time ago, I remember those scary first days/years. But this isn't 1992 anymore with only one medication. It's been nearly 3 decades and the science has rapidly expanded and improved. Take your meds daily, try to live and eat healthier, reduce stress, exercise, and make plans on living as long as you would have if you didn't have HIV - because that's the actual outcome for treatment. ;) :)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 10, 2021, 07:15:43 am
Τhanks all of you...
You really support my mental health in this stage.

My concerns are two
- my one kidney only works (90-95% and the other one helps only 10-5%)
How long can I leave with these medications?
I am lucky to have TAF instead of TDF , still not totally innocent for body and kidney when accompanied by emcitritabine

- Latent, dormant CMV that I have,
, Won't wake or start some kind of cancers?

- I accept all your statements.
But I read on aidsmap that VIRAL SET POINT BIGGER TO 10000 , MEANS 8 YEARS SHORTER LIFESPAN
I also have latent CMV, this kidney problem and cancer Donna giving from family..

Should I expect with 50 millions before treatment initiation to live at least until 60 to see see a grand child???

Good morning for all you brothers
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 10, 2021, 07:50:46 am
Dormant CMV...

Look in some regions of the world like the US, half the adult population has it. Stop stressing about nothing and things that aren't currently an issue and might never be.  ;)

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But I read on aidsmap that VIRAL SET POINT BIGGER TO 10000 , MEANS 8 YEARS SHORTER LIFESPAN

Sure it's one study and within that group of high viral load, it's often late diagnosis (AIDS) and people with multiple of other conditions, OI's and co-mobilities like drug usage and alcohol abuse etc.

Also, with these studies it's often just averages taken from the past years, lots have changed including the treatment compared to past groups, it's also not an individual forecast, although, 8 years less I'll take it.  :)

The average lifespan here has passed 83 years for a man, take 8 away it's still better than dying right now! :D Btw, going forward always include links to studies etc, thanks.

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How long can I leave with these medications?

Decades, and it's not even needed. HIV medication keeps improving so it's not like you will need or have to take your current meds for that long. Also, you will get regular checks to make sure things are fine including kidney function etc.

Look, I've put plenty of easy to digest references and information in the "Just tested positive" welcome thread, I also added things about starting treatment early and life expectancy etc. It' might be useful to have a look https://forums.poz.com/index.php?topic=2276.0

However, don't get focused on these topics.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Bucklandbury on July 10, 2021, 11:45:28 am
I got an AIDS diagnosis in mid-March. I am pulling for you, buddy! Take your ARV med(s), get on an antibiotic for sure for now since your CD4 count is under 200, and go see your doctor as ordered. Good luck!
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on July 10, 2021, 03:17:53 pm



       ojo.         Who remembers the dx FULL BLOWN AIDS?. And now, •acute hiv infection”, …@OP, you are going to be fine, there are a lot of members on here who have gone through the same. The formula to get a successful treatment is, DISCIPLINE taking your med/s and a positive ATTITUDE…good luck and please keep us posted, we are here for you…ah!, stay away from doctor google and take care of yourself until you get better number of soldiers
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 12, 2021, 09:01:32 am

However, don't get focused on these topics.

It's not that easy Jim. Thanks for your kind support. It's good for me now.

I am one month and ten days on arvs.
I start feeling I diggest illness, but really, sometimes I search all the time this in Google.

Why? Because I have this kidney problem. Next week I have ultrasonic and some specific tests for kidney.

I feel happy that I don't need to take TDF tenofovir , but even emtricitabine which is in Descovy is a non-issue for Kidneys.

Many mornings, I wake up because bslight pains in kidney that's why I have all rest day stressed and some sadness.

Can I hope for safer a bit meds for hiv in future? Ok, I stop thinking about cure.
But some safer meds for kidney???
Is any doctor here knowing something related ??


Jim yes, next times I will post links and pics.
I formatted my phone so I will find only pic in screenshot in Google photos. I mean this about life expectancy Bye guys
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 12, 2021, 10:01:06 am
Hiya,

The Descovy combination pill contains tenofovir alafenamide (TAF) and emtricitabine, it's considered kinder on the kidneys than its predecessor (TDF).

However, it's not a conclusion that kidney function will be an issue as a result of TDF or TAF for everyone taking the meds. That's simply not the case, although it can be, thankfully this is included in monitoring so they can switch or change your meds should there be any concerns. 

There are also living donor HIV-​to-HIV kidney transplants nowadays and the people living with HIV with only one kidney go on taking their meds and living their lives.

Look talk to your doctor about your kidney concerns and the TAF,  see what they say and what the latest measurements are.  A good idea is to write some of the questions down on paper, so next time you see your HIV doctor you don't forget to ask or express a concern that you have.

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Many mornings, I wake up because bslight pains in kidney

So I don't know if the pain is a new issue or a change for you but talk to your doctor sooner if you are in discomfort.

Best, Jim

https://www.poz.com/basics/hiv-basics/taf-versus-tdf-difference
https://www.aidsmap.com/about-hiv/chronic-kidney-disease-and-hiv
https://www.poz.com/article/descovy-prep-works-equally-may-safer-kidneys-bones
https://www.aidsmap.com/news/aug-2020/kidney-transplant-between-people-hiv-safe-says-us-study
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 12, 2021, 10:18:02 am
I got an AIDS diagnosis in mid-March. I am pulling for you, buddy! Take your ARV med(s), get on an antibiotic for sure for now since your CD4 count is under 200, and go see your doctor as ordered. Good luck!

My doctor asked what lymphocytes I had normal before illness.
He told me is normal a dive to half or to 1/3 of cd4 in acute phase, that's why he didn't give me protection pills for opportunistic because anyways I have low cd4.

But next week I have meeting with hematologist to search and find for what reasons my body didn't create enough WBC generally.

I will provide you with all information.

She is the best, she is professor of hematology in Athens Doctors School in Greece.
I hope she will be able to help ...

Guys, is it so bad to love trans women, so to pay with our lives, psychology, pills ,stigma??
I have many friends meeting shemales and we only kid with each other. But if you get the virus then you are stigmatized....

Life is slut and being fucked... My teacher in secondary school told , when he lost his daughter from head cancer...

Anyways..
The positives now.
Jim and all you help me to forget a bit ..

So , tomorrow my new girlfriend arrives from Ukraine , we will go for holidays five days to Greek islands... I am happy...
But I'm not happy I cannot have free sex with her....
Can she give me oral without ejaculation with safety??

Final question.
I had hpv 10 years ago..in penis.
Now I'm afraid that being hiv positive , if I give her oral and she has hpv , maybe I can get it in my throat?

Can I have vaccination for hpv in my age35-36???
Even thinking that I had some hpvs warts in decade past. Can I have for further protection from the rest types of hpv that the vaccination will cover???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 12, 2021, 10:32:13 am
Hiya,

Look, please refrain from using the term "shemale" - Thanks.

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Can she give me oral without ejaculation with safety??

Look giving a blowjob is a risk, a minute HIV one considering the barriers but it's not totally risk-free.

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I had hpv 10 years ago..in penis.
Now I'm afraid that being hiv positive , if I give her oral and she has hpv , maybe I can get it in my throat?

There is no such thing as risk-free sex. There are STI's that can be passed onto you in the throat, you can also use a dental dam to reduce the risks.

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Can I have vaccination for hpv in my age35-36???
Even thinking that I had some hpvs warts in decade past. Can I have for further protection from the rest types of hpv that the vaccination will cover???

HPV vaccine depends, certain nations still limit it to lower ages, but talk to your doctor in Greece.

https://www.cdc.gov/vaccines/vpd/hpv/hcp/recommendations.html
https://www.poz.com/article/hpv-vaccine-gardasil-effective-people-hiv-age-27
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 12, 2021, 10:36:11 am
So do I understand correctly you are no longer with your wife & child but the new girlfriend?

Well, whatever the case, keep in mind once you have achieved an undetectable viral load* for at least 6 months, you can't sexually pass on HIV to your wife & other partners. This is also known as Undetectable = Untransmittable (U=U)
* https://forums.poz.com/index.php?topic=71864.0

Until then condoms & PrEP would be something for them to consider to reduce their HIV risks if you are having sexual contact.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 12, 2021, 11:06:40 am
I am with my family.
I'm sorry 🥺 but all my ancestors were naughty.
And we all had older women.
And my son shows signs of being much sexyally attracted from now.

Jim, friends, don't judge me..
I cannot control when I see women with garters , well shaped etc.
So , Now that I believe I will not live a long (only all you make me feel better) I found woman in tinder for holidays for vacation for week.

But I am good person, I don't want to infect noone.
I don't know where I will hide my pills.
If she asks me.
Maybe I put on fat burner box pills,

This makes me happy..regenerates me a new woman, with good feelings of falling in love etc...
I feel I forget.... hiv.
It makes me avoid bad thoughts like suicide that I had in first weeks of diagnosis.

My wife knows... She accepts to live with what makes me happy.. I adore her .. she kept me alive...
But she knows this makes me forget stress and she loves me and I appreciate this.
If I hadn't my wife I would suicide.

But new girl for nice moments makes me happy , forget , relax ...now , wife is with son in her parent's home for month for vacation in forest with cold climate...so I can leave and do naughty vacation..
Anyways.
Just because you asked me.

Only I am worried if my son some day finds my toothbrush and he is infected from me... I hope air kills virus so he will not be infected....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 12, 2021, 11:26:58 am
Hiya.

Your son is not going to get HIV from day to day contact with you or household objects you have touched or used.

I'm glad to hear your wife is supportive. Not too sure what to say about hiding your meds from the GF. I tell people about my HIV status so I've never had to hide them but I am sure your GF will not be going through your stuff, I would find that strange at least but if you want to further hide your meds in another container I am sure you will manage.

If you keep having thoughts of suicide though do talk to your doctor about this, you are not alone and there is support. It's also important for them to know so they can consider what HIV meds you are getting etc.

Jim
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 12, 2021, 11:46:34 am
I love you all here ❤️ for support...
I saw yesterday an Irish Dance from girls...
Amazing...
I love traveling.
I haven't yet been in Ireland.

How can I travel within Europe with my meds??
Also Jim what about traveling generally abroad until injection monthly drugs arrive in Greece?

I want to go to Singapore and watch F1 grand Prix.
How can I go?
I read that they don't accept positives.

What a stigma.. and it's just a virus and controlled chronic illness...
Wtf?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 12, 2021, 12:35:09 pm
Pre-covid I travelled 4-5 times per year at least within the EU, I always kept my meds in my hand luggage in their original packaging and was never asked or questioned about it. I did always carry a letter from my GP stating that the meds are for personal use and treatment of a manageable condition should I ever be asked.

The only time I was asked about it was in the US and that was my own fault as I had the bottle in my fleece/jacket pocket at the time, and it did not become an issue either, was silly of me to fiddle with things in my pocket at customs and I should have kept it in my hand luggage.

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I want to go to Singapore and watch F1 grand Prix.
How can I go?
I read that they don't accept positives.

As far as I am aware short term stays are not a problem.

https://www.hivtravel.org/Default.aspx?PageId=143&Mode=list&FullSearch=singapore

https://afa.org.sg/law-and-hiv-in-singapore/
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 12, 2021, 02:52:26 pm
Jim... Thanks for everything.

Can you share with me some information?
When is best time for visiting Ireland so I can watch live festivals and local culture tradition like this https://youtu.be/uFQJ2sLKN8s
I really now saw my life differently. I wanna see as much as I can before I go to above sky.

Finally I am sorry about term shemale. I didn't know is bad , sorry. What is the best word to refer to? Trans woman?

See you all there.
Hope God keep us alive...

I also asked in previous message, should I wait soon better treatment for kidney perspective? I mean injections or sth else??
Thanks.
Good night guys
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 12, 2021, 03:32:58 pm
Quote
When is best time for visiting Ireland so I can watch live festivals and local culture tradition like this https://youtu.be/uFQJ2sLKN8s
I really now saw my life differently. I wanna see as much as I can before I go to above sky.

April to Sept. It will rain but at least it will be wet and warm instead of wet and cold.

Although, if you ask me forget about that dancing nonsense - It's a bit like visiting Greece and hanging out in Athans all day and if that's what you're into then it's fine of course.

The best places to visit and explore in Ireland are more remote or smaller towns, places like Malin Beg and that somewhat touristic already.

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I also asked in previous message, should I wait soon better treatment for kidney perspective? I mean injections or sth else??
Thanks.
Good night guys

HIV Treatment, as explained, is fine and you need it now. Give yourself time to adjust to treatment and keep monitoring things with your doctor. No need to wait with treatment and should your current treatment cause any problems there are other combinations and there will be better treatments in years to come.

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Finally I am sorry about term shemale. I didn't know is bad , sorry. What is the best word to refer to? Trans woman?

No need to apologize or at least not to me. We all can make mistakes or be unaware hence I mentioned it.
Anyhow, I know enough to know that terms like that are outdated.

http://www.basicrights.org/wp-content/uploads/2015/09/Trans-Media-Reference.pdf
https://www.albertahealthservices.ca/assets/info/pf/div/if-pf-div-terms-and-phrases-to-avoid.pdf
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 17, 2021, 04:04:46 am
Hello Jim...good morning..
Thanks for answers ..I will have in mind.

I am wondering about sth very much...
I was found with 50millions and only 160cd4.

This is progressed aids or to be aids it also needs to have passed the acute phase, latent phase 2 and after some years??? Because I know I was on peak of my acute phase...
But if in acute phase I have so much like in late disease , does it mean my immune cannot fight nothing?

I am asking because if I had so big viral load, maybe it means easily hiv will destroy my left immune system, despite the use of art. So I will live shorter....
Is my thought true???

Please someone answer all my questions..
It's too early and I sometimes fall in stress situation with depression I think

Good morning all
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 17, 2021, 05:59:39 am
Hiya,

I think you should have a read of "How do I know my treatment is working?" in this lesson https://www.poz.com/basics/hiv-basics/starting-hiv-treatment and also the welcome thread as it might be useful to have a look https://forums.poz.com/index.php?topic=2276.0

When is your next follow-up appointment with the HIV doctor/clinc?

Quote
I have so much like in late disease
Quote
This is progressed aids or to be aids it also needs to have passed the acute phase, latent phase 2 and after some years???

Generally there are 4 stages of HIV infection, but its a tad misleading as you can go skip stages going to stage 4 sooner.

Advanced HIV disease (AIDS) when being diagnosed most commonly (I think) would be defined as a CD4 cell count below 200 cells/μl or the presence of an AIDS-defining illness regardless of CD4 count.

In the USA, the CDC's definitions and stages are slightly different:
Quote
People receive an AIDS diagnosis when their CD4 cell count drops below 200 cells/mm, or if they develop certain opportunistic infections.
https://www.cdc.gov/hiv/basics/whatishiv.html

In Ireland for reporting its defined as: -
Quote
CD4 cell count at HIV diagnosis can be an indication of how long a person has had HIV before being diagnosed. For surveillance purposes, late HIV diagnosis is defined as CD4 cell count less than 350 cells/µl or an AIDS defining illness at diagnosis.

Advanced HIV infection is defined as a CD4 count of less than 200 cells/µl or an AIDS defining illness at diagnosis.
https://www.hpsc.ie/a-z/hivandaids/

Quote
I am asking because if I had so big viral load, maybe it means easily hiv will destroy my left immune system, despite the use of art. So I will live shorter.... Is my thought true???

With CD4 count of less than 200 we tend to be more fundable/at risk to certain infections and complications.  However, you doctor could have prescribed antibiotics to reduce the risk of certain OI's ...

Anyhow, you have started ART and this start to stop HIV from continuing to do unchallenged damage. Within 6 months if all is going well at least 90% of the viral load will be suppressed already and your immune system will be given a break from fighting a pointless battel so it can focus on better things.

I had mentioned this before, and plenty of other members have jumped in on this with real world examples but if something is unclear let me know.

Quote
you don't have to start planning and preparing your wife & child for your death soon because of your HIV status, and there are plenty of members here with far worse results than your who are doing just fine today.

The low CD4 counts mean you are at an increased risk for certain OI's and cancer, however, once the viral load reduces and the body can "heal" the CD4 counts should also increase again with time. Once the VL is suppressed and it will be the CD4 count become somewhat less relevant. That said plenty of people still have low CD4 counts and are perfectly healthy.

As a group we are prone to certain conditions more frequently or sooner in life, that does not mean it will be an issue for you and you will see your doctor or clinic during check-ups to monitor things and treat any issue early.

Quote
You could live for another 50 or 60 years, your 35 now. Depends on what happens in your life but don't smoke, eat healthy and exercise if you want to live healthier and perhaps longer, and considering you are living with HIV take your meds.

Quote
Like I said you could live for the next 50-60 years, you could also be run over by a bus tomorrow. HIV is not an automatic death sentence or short life span, treat it and look after yourself to live a healthier and longer life if you want.

Quote
Look, I've put plenty of easy to digest references and information in the "Just tested positive" welcome thread, I also added things about starting treatment early and life expectancy etc. It' might be useful to have a look https://forums.poz.com/index.php?topic=2276.0



       ojo.         Who remembers the dx FULL BLOWN AIDS?. And now, •acute hiv infection”, …@OP, you are going to be fine, there are a lot of members on here who have gone through the same. The formula to get a successful treatment is, DISCIPLINE taking your med/s and a positive ATTITUDE…good luck and please keep us posted, we are here for you…ah!, stay away from doctor google and take care of yourself until you get better number of soldiers

a small personal story to support what Jim has told you:
in the late 90s when, unlike today, there were few meds and almost all had side effects, I was hospitalized with AIDS at age 36 with a viral load in the millions and only 5 cd4s. It's been 37 years now since I was infected (and 29 yrs on meds), I'm getting close to turning 60,  I've been undetectable for decades, my cd4s are near 500, and I could not be happier or healthier.....all thanks to staying adherent to HIV medications. No cancers, no issues, and if my Grandmother is any example as she is within a month of turning 104, I'm expecting to not only live these 25 yrs since that hospitalization but I'm expecting I may have another 40 years on top of that. :)
one last word of advice: don't get hung up on wishing for a "cure". Today's meds are quick and easy to take with few to no side effects and very effective at suppressing HIV. I take a few pills every morning and get on with my life not thinking about HIV these days....and you'll get to that point too in the not too distant future if you stay adherent to daily meds.

As far as the Oxford trial, the med they are currently researching is designed as a vaccine ... a preventative. Unfortunately, we are already HIV positive so a vaccine might not do anything for us. Of course, these vaccines are also considered for whether they could be a "therapeutic vaccine", which means it might suppress HIV for the long-term (months to years).

Once infected and then treated, HIV decreases but doesn't completely go away. Tiny bits remain in our bodies but dormant. That's why we take meds daily - to suppress any of this remaining HIV that becomes active. Until a complete cure is created, HIV positive people will need to remain on some type of medications, whether it be daily or (coming soon) a long term injection that lasts for months at a time.

Even though I tested positive a long time ago, I remember those scary first days/years. But this isn't 1992 anymore with only one medication. It's been nearly 3 decades and the science has rapidly expanded and improved. Take your meds daily, try to live and eat healthier, reduce stress, exercise, and make plans on living as long as you would have if you didn't have HIV - because that's the actual outcome for treatment. ;) :)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 17, 2021, 06:10:10 am
Just to add, don't focus too much on definitions etc., It's relatively pointless, so instead, just see your first results as a starting point and now you are on meds your follow-up appointments will show the trend. The journey and trend in your labs over the upcoming months/year of starting to suppress the virus are much more important.

BTW - When was your next follow-up appointment with the HIV doctor/clinc?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 17, 2021, 11:12:17 am
Hello Jim , I'm sorry for the late response .. today I return to Athens from holidays.
Yesterday , I slept at 5am.
Is it very bad for immune to stay late ?? Because we woke up at 10 to leave room empty...
I read we, positivs, should sleep early and not hangover...
This happens even when in ART???

My question to my previous message Jim and bros , is that I'm afraid, that if my body could not control within normal limits the virus during acute hiv, it means for me , that when we will have more long lasting treatments etc, my body will not be able to control virus and suppress it without art even for a month for example...
Is this correct??? My thinking I mean.....

Something more.
I have some sore , bit not painful, just like scratched with a removed top layer of skin inside the cheek low at the level of teeth...
Is it means my body doesn't work correctly?
Or is it usual?

I am so scared guys...
I cannot enjoy my life .
The Girlfriend is angry on me because today she stays last night in Athens, she wants clubbing, but we did it yesterday and I will not do for second day immediately...and I cannot tell her the reason.
Also , you have to know I protected her... Third day ste started and tried to put my penis inside her without condom. And she told I am boring that I didn't get into her without protection...
All men don't without protection.
And now I am worry that I may have taken some sti on my skin...

Anyways.
Hope you good health my friends
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 17, 2021, 11:13:45 am
Also ten days ago I had blood sample for month after start of treatment.
I will have results this coming week.
I will inform you.
I hope my cd4 250-300
And HIv level 5-10 million
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 17, 2021, 01:06:09 pm
Hiya,

Quote
I slept at 5am.
Is it very bad for immune to stay late ?? Because we woke up at 10 to leave room empty...
I read we, positivs, should sleep early and not hangover...

Lack of sleep is not good for anyone, however have the odd night or few night of less sleep happens, that's life and normal. As for the hangover, drinking excessively is not great of anyone.

Quote
My question to my previous message Jim and bros , is that I'm afraid, that if my body could not control within normal limits the virus during acute hiv, it means for me , that when we will have more long lasting treatments etc, my body will not be able to control virus and suppress it without art even for a month for example...
Is this correct??? My thinking I mean.....

No, it's not correct.

Your Viral load is not somehow special and ART will suppress & control the virus within 6 months most likely if not sooner, for now you will need to take your medication daily.

I'm not sure what you mean with stopping treatment for a month, don't do that because if you stop treatment the viral load will come back and how quickly depends on things like what the reservoir size is like etc.

Quote
Something more.
I have some sore , bit not painful, just like scratched with a removed top layer of skin inside the cheek low at the level of teeth...
Is it means my body doesn't work correctly?
Or is it usual?

No it means you need to see a doctor/dentist. This happens to HIV negative peers as well.

Quote
The Girlfriend is angry on me because today she stays last night in Athens, she wants clubbing, but we did it yesterday and I will not do for second day immediately...and I cannot tell her the reason.
Also , you have to know I protected her... Third day ste started and tried to put my penis inside her without condom. And she told I am boring that I didn't get into her without protection...
All men don't without protection.
And now I am worry that I may have taken some sti on my skin...

HIV does not stop you from going clubbing and as for STI's, well sex comes with risks. There is no such things as "safe" sex just safer sex. No need to panic every time you have sex though, just use condoms to reduce the risks from STI's and test out of routine at least yearly.
 
Jim 

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 19, 2021, 07:55:49 am
Ηello guys...

I am irrational or logical?

My girlfriend , now together for 1 year and a month..
She knows about my situation, she accepts my health issue and wanna continue with me..
But, in this phase of my life..
You know...
All time I read about Illness , I want to know about new treatments, start collecting every paper for some medical tests....also I have my job (should I afraid of losing my job due to hiv? I work in special forces. What about USA or UK? Do people with hiv lose their jobs due to this?) , I have second job and it's too early to go along her desired path...
She wants normal relationship with talking with me many times per day , she wants meetings...but this period I prefer my friends with whom I laugh a lot and I don't have to be sad... because many talks with her make me sad...
I explain I am not woman, so as a man I prefer more to be with friends , but not because I don't love her but because I want time to feel well and go for coffees with friends and also to rest more.....

Am I irrational or is normal that I haven't digested yet my illness, I have to manage everything...see doctors....etc related...

And she is now sad and crying because she decided to break up and go ther country Poland again back to her home...she cries because she will be alone there , only with friends and her brothers family...

I want to be with her , but now I need time for me... without stressful obligations, responsibilities and duties....

I am feeling like stressed from all this and with hiv I have to be and feel more free ... And I decide , or start deciding that I have to be with my wife only because she understood everything and doesn't stress me almost at all... So ????

Please help me because I feel sad when she calls me and complains all time because I am not with her..

I explain her she has right from her side but if she loses a lover she will have all her HEALTHY life ahead...she is only 26.
And in don't know with 160 cd4 how much I will live more...

So in front of my situation I cannot even accept that she wants something that will be opposite to my health...

She has to understand , correct or not?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 19, 2021, 08:14:07 am
Is the girlfriend in Poland the same as the new girlfriend from Ukraine?

Anyhow, if you want to leave your wife and have a relationship with the GF that's up to you. I don't see why your HIV status would be an issue unless she does not want to be with someone who has a manageable condition.

Understand you work in the military, not sure if that's going to be a problem. I know 5-6 years ago there was reports of people living with HIV being laid off from the military in Greece.

Quote
is normal that I haven't digested yet my illness

Yeah, well it depends on the person but it can take time to digest the idea of living with HIV.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 19, 2021, 09:56:21 am
As for girlfriend is about a year and I started sth with her when we almost divorced with wife. So I talked about Polish girl. Yes it will take me time to understand to continue my life like similar almost normal , but until then I need more my friends and my son... This girl cannot understand she has everything and I need special mental and medical care this period...
Correct??

But now , I needed some holidays with new girl to renew my mental and psychology...this girl from Ukraine. We went for holidays for 4 days, and yesterday she left to Ukraine back. It was fine, but we didn't greeting each other , because we argue when she saw cold behaviour from me when I stopped being her tool for making photos, buying meals and generally understanding that she used me only for holidays... Almost all women the same....

Ι κnow that case... It was in 2013.

I know also about a policeman with hepatitis B who fired, and then after lawyer of citizen took action, he was hired again but for office work...

Is HepB better than HIV?
Better...you know what I mean!!!

I don't know.
There is some social helping monthly income for plwh in Greece and I'm afraid to ask for it because they maybe then fire me.
And I'm not afraid of fire but for stigma...
All will know then and I will be sorry for my son's life after that...school social stigma etc...
I don't know what to do...

Bye friends..
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 19, 2021, 04:35:18 pm
https://www.poz.com/basics/hiv-basics/oral-hairy-leukoplakia-ohl

I read this .. I did some scrab with my finger only and after washing my hands , and seems to be removed..it's mostly like scrubbed skin , but also I have one more patch only in the upper mouth between bcheek and gum which seems to be removed after scrubbing with my finger...

So it seems more as thrush....
I am 3 months infected , 1,5 month on art.
Tomorrow I will know if I have more WBC or same as before...

So , should I worry a lot?
I read on some article that oral hairy leukoplakia maybe a precancerous oral manifestation..

Please a bit help...

I am again getting paranoid...

I cannot live like this...all time worrying about next opportunistic infections or cancer....

Ouff....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 19, 2021, 04:41:19 pm
Like in picture but one only in the upper mouth and more in the lower mouth between cheek and gums...

https://geekymedics.com/wp-content/uploads/2020/04/Acute-pseudomembranous-candidiasis.jpg
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on July 19, 2021, 07:47:26 pm
which seems to be removed after scrubbing with my finger...

So it seems more as thrush

So , should I worry a lot?
I read on some article that oral hairy leukoplakia maybe a precancerous oral manifestation..


I am again getting paranoid...
with a cd4 count under 200 you very well could be susceptible to thrush. Thrush is very common at all ages from a lot of reasons; but especially when someone has a weakened immune system - and it's very treatable. You'll need to get a doctor to check it out.

there's nothing wrong with worrying about your situation. Recently diagnosed and bad counts - that's a mental, emotional and physical unexpected interruption in your life and sure to cause distress. But notice I wrote "interruption". Not the end of your life, just an interruption until you get the virus and any current side issues under control.

however, even though you shouldn't worry too much now that you're on medications, you do need to worry about any issues you might have. But that doesn't mean hours of paranoid research on the internet. Instead talk to you doctor.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 20, 2021, 12:46:01 am
First of all...you are my hope...thanks to you , all, I feel better many times after I read your messages...thank you for this

it's very treatable. You'll need to get a doctor to check it out.
should I expect it will leave itself without treatment??

Quote
Recently diagnosed and bad counts - that's a mental, emotional and physical unexpected interruption in your life and sure to cause distress. But notice I wrote "interruption". Not the end of your life, just an interruption until you get the virus and any current side issues under control.
I am so sorry because I feel so pessimistic about controlling these big amounts of millions ..
Also , I read 10' ago about this lenacapavir novel two times per year drug injected under the skin ...but when reading about side effects I read some kidney failure...
You see? I have everything bad...
Bad counts also one kidney .. still believing I can control the virus? And live for 20-30 more years..????
I lose my hope...
Today maybe I will know how much cd4 I had at 28 days after treatment...
Because I had 167 when diagnosed...not when started treatment.. because after diagnosis I started treatment after 2 weeks. So maybe I had much less cd4 when starting...

Quote
however, even though you shouldn't worry too much now that you're on medications, you do need to worry about any issues you might have
Issues? For example?

Anyways , I can only hope...
Because this is not life...having all the time OIs and feeling sad and etc....

Buy my friends
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 20, 2021, 05:25:49 am
At 28 days of treatment.

276 cd4
5600 WBC
Not yet viral load

But still cd4/cd8 , still 0,4 , which I read is bad because I have more chances for cancers and some specific infections

On diagnosis before treatment , I had

167 cd4
2800 WBC
48 million VL
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 20, 2021, 05:47:16 am
Hiya,

Again start providing links for things you are quoting or saying to have read.

Quote
Also , I read 10' ago about this lenacapavir novel two times per year drug injected under the skin ...but when reading about side effects I read some kidney failure...

The phase 2 study results for people with resistance who got a 6-month shot + daily ART or the small ongoing first-line treatment study?

Where did you read about some kidney failure?

As far as I have read, in one of the studies, there were some cases of lowered kidney function but these were more common in the bictegravir/emtricitabine/TAF comparison group. Not seeing any mention so far of kidney failure though and I don't see how it's an issue for you.

https://www.aidsmap.com/news/jul-2021/novel-twice-year-injected-drug-suppresses-multidrug-resistant-hiv-most-patients

https://www.aidsmap.com/news/jul-2021/twice-year-injected-drug-shows-promise-first-line-hiv-treatment
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 20, 2021, 06:18:20 am
At 28 days of treatment.

276 cd4
5600 WBC
Not yet viral load

But still cd4/cd8 , still 0,4 , which I read is bad because I have more chances for cancers and some specific infections

On diagnosis before treatment , I had

167 cd4
2800 WBC
48 million VL

The only result that really matters at the moment is the VL to know if the virus is starting to be suppressed and until your viral load is suppressed and you have had time to heal I would not expect any real improvements. The cd4/cd8 ratio may improve over time.

https://www.aidsmap.com/about-hiv/cd4cd8-ratio
https://www.poz.com/article/monitoring-health-viral-load-cd4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203616/

with a cd4 count under 200 you very well could be susceptible to thrush. Thrush is very common at all ages from a lot of reasons; but especially when someone has a weakened immune system - and it's very treatable. You'll need to get a doctor to check it out.

there's nothing wrong with worrying about your situation. Recently diagnosed and bad counts - that's a mental, emotional and physical unexpected interruption in your life and sure to cause distress. But notice I wrote "interruption". Not the end of your life, just an interruption until you get the virus and any current side issues under control.

however, even though you shouldn't worry too much now that you're on medications, you do need to worry about any issues you might have. But that doesn't mean hours of paranoid research on the internet. Instead talk to you doctor.

Fully agree with the above.

Quote
should I expect it will leave itself without treatment??

Thrush happens, see your doctor and treat it before it becomes an issue. This is a common enough issue even under HIV negative peers but with a lower CD4 count as a group we're are more prone to it.

https://www.poz.com/basics/hiv-basics/candidiasis-thrush-yeast-infection

Quote
Because this is not life...having all the time OIs and feeling sad and etc....

Billions of people have health issues, thankfully, you can manage your HIV but it will take medication & time.  You will not have to be having OI's all the time. Meds will suppress the virus, your immune system will "heal" and things will be better. You might feel worse at first given as your immune system starts again and finds & fight things it had been ignoring or had been too weak to deal with but that stage will pass.

As for feeling sad, you have just been diagnosed so it's not uncommon to feel sad, scared, worried etc. Seek out support, talk to your doctors about how you are feeling and connect with local support groups and peers if possible.

Quote
As for girlfriend is about a year and I started sth with her when we almost divorced with wife. So I talked about Polish girl. Yes it will take me time to understand to continue my life like similar almost normal , but until then I need more my friends and my son... This girl cannot understand she has everything and I need special mental and medical care this period...
Correct??

I can't comment on the need for special medical or mental care. You and your doctor would need to determine if special care is needed.

Look if the girlfriends are not supportive or don't understand that digesting the diagnosis isn't easy or that you need time to get your head around it then perhaps they are not the best people to rely on for support during this time.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 20, 2021, 07:13:26 am

Where did you read about some kidney failure?

As far as I have read, in one of the studies, there were some cases of lowered kidney function but these were more common in the bictegravir/emtricitabine/TAF comparison group. Not seeing any mention so far of kidney failure though and I don't see how it's an issue for you.

https://www.aidsmap.com/news/jul-2021/novel-twice-year-injected-drug-suppresses-multidrug-resistant-hiv-most-patients

https://www.aidsmap.com/news/jul-2021/twice-year-injected-drug-shows-promise-first-line-hiv-treatment

Yes, exactly these links...

""
There were some cases of lowered kidney function but these were more common in the bictegravir/emtricitabine/TAF comparison group.
""
This bictegravir/emc/TAF = the bictarvy, correct??

So I have to be afraid of switching to bictarvy ?

Because my doctor told me , that I maybe switch to bictarvy in six months that biktarvy will be available in Greece

I didn't understand this "but these were more common in the bictegravir/emtricitabine/TAF comparison group. ""

Does it mean who have injection of lenacapavir plus biktarvy???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 20, 2021, 07:46:23 am
Hiya,

Quote
Because my doctor told me , that I maybe switch to bictarvy in six months that biktarvy will be available in Greece

I didn't understand this "but these were more common in the bictegravir/emtricitabine/TAF comparison group. ""

Does it mean who have injection of lenacapavir plus biktarvy???

25 people took bictegravir plus emtricitabine/tenofovir alafenamide. It's nothing for you to stress about just because someone within that group of that study had a somewhat lower kidney function on a drug you don't take and without even knowing their medical history...

If you switch, and that's an if, well you and your doctor will assess your kidney function at that time and concerns before selecting the best medication available and if that is Biktarvy you could be perfectly fine with that. This is why you will have check-ups to make sure things are going okay and if they are not and it's related to the meds they will find a different combination for you to try,

No point stressing about issues that have not happened and may not happen in regards to your meds.

https://www.poz.com/basics/hiv-basics/hiv-kidneys

Try to focus less on "what ifs and maybe's".  ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on July 20, 2021, 08:41:15 pm
My Dr just switched me to Biktarvy to help my kidney function. Everything I read about it says it is fairly easy on the kidneys. I will find out in two months whether that is correct.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 04:34:51 am
Good morning there.

Even with a better (seem to..) immune now, I have this oral thrush for a week already today... Should I worry for some precancerous condition or is it something that will be resolve itself???

It's only 1-2 sq cms between cheek and gums ..
Should I go to dentist, stomatologist?
Or to my hiv clinic?

Maybe it's from ART?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 22, 2021, 06:50:13 am
Hiya,

The change in your CD4 count was only minor, it's barely above 200 now and your system is still recovering with an unsuppressed viral load.

The thrush needs attention from your doctor and treatment, no need for drama but treat it before it becomes a real issue.

Jim:
Quote
Thrush happens, see your doctor and treat it before it becomes an issue. This is a common enough issue even under HIV negative peers but with a lower CD4 count as a group we're are more prone to it.

https://www.poz.com/basics/hiv-basics/candidiasis-thrush-yeast-infection

Leatherman:
Quote
with a cd4 count under 200 you very well could be susceptible to thrush. Thrush is very common at all ages from a lot of reasons; but especially when someone has a weakened immune system - and it's very treatable. You'll need to get a doctor to check it out.


Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on July 22, 2021, 09:49:43 am
Or to my hiv clinic?

Maybe it's from ART?
Meds don't cause thrush, an unhealthy immune system does. You answered your own questions though - go to your doctor/HIV clinic. They've seen this situation thousands of time and they have got the experience to properly diagnose your issue and prescribe the right medication to treat it.


The thrush needs attention from your doctor and treatment, no need for drama but treat it before it becomes a real issue.
yep. I had thrush a number of times back in my early days living with HIV in the mid-90s since I was so very sick for so long. While none of the cases of thrush I had seemed too bad, the thrush that I couldn't see deep down in my esophagus left scar tissue that can cause me issues when swallowing....25 yrs later.


Of course, I'm not saying that you gpapadop91 will have the issues that I have had from thrush, but what I'm saying is that you need to go get that thrush diagnosed and treated so you don't have the issues I have. ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 10:32:54 am
Hey thanks for answers, but doctors in hiv clinic saw this...
They told me it's looks like thrush but only minor and small in surface so check it if it gets bigger or not...
They didn't tell me something more... Just watch it...
So I don't trust with such answers.
And also you tell me to treat it before it goes wrong...you mean it can be cancer or what?

Yesterday , hematologist told me it's ok that I increase cd4 , need to follow my therapy consistently , and I will be better.
She told me maybe I will not have more than 4-500 or max 600 in the long run because anyways my immune , even before illness didn'take more than 5-700 cd4 s.

And count does not matter... People with more cd4 had more illnesses than some others with less....


So , with less cd4 should I expect to live shorter or what???

I'm starting worry of thrush.

Please leatherman.
I didn't understand.
After 25 years , untreated thrush caused problems to your easoohagus or you have. thrush for 25 years untreated and now it became thrush??

Ouf....
I feel so unsafe , so vulnerable to all illnesses, I'm so sad everyday...
Kidney
Thrush
Everything...

Can I expect with eating yougurts and by time to see more cd4s and treat this small thrush only by itself???
Or I have to take pills...????
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 12:52:15 pm
https://www.europeanpharmaceuticalreview.com/article/143332/the-current-and-future-landscape-of-hiv-treatments-and-vaccines/

Current HIV therapies
“The main focus of HIV treatment to date has been on antiretroviral therapy,” said Forkin. She explained that antiretroviral therapy does not cure HIV, but instead suppresses the virus and slows down its progression in the body, thereby preventing opportunistic infections and AIDS-related deaths

So this "slow down" means it's (ART) only makes the progression to AIDS slower, or can we really stop progression if we can suppress the virus to undetectable?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on July 22, 2021, 01:12:18 pm


              ojo.     @gpapadop91…hi, if the doctor didn’t prescribe med for your thrush, you should be worried, as soon as your treatment starts kicking the virus butt, your thrush will go away.

If I may, don’t think about the future, what’s going to happen, nobody knows the future, if you were to get cancer or something else, then, you and your doctor will take care of it. Try to live the present, be discipline with your meds and try to be positive, you are going to be fine…good luck and please, keep us posted…hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 03:46:00 pm
Love u all for your support , Jim too... I may put too much press with multiple questions... I need help, more mental...
I want to see my son succeeding his life and teaching him the very difficult life by supporting (not by pressing..) ,
I understand Jim who in my eyes seems a bit more stric with me (🤗🤗🤗 joking) but he wants to be realist. I don't hide you I search every week news about hiv cure treatment.
I hope , wish for this cure. Because that day I will sell 1 of two homes that I have to give half to people with helath and stigma problems and other half for partying with all you and my family...
Some times I am very disappointed by reading bad things like (almost same life expectancy but with far fewer healthy years...or Even suppressed virus by art however kidney damage has been associated with chronic inflammation...or I don't know if with art we succeed in stopping progression tonAIDS or are we going to have it for sure but a bit later...)....
And sometimes I feel well....
I don't know but it's unfair because of some sexyal behaviours to have this illness forever....it's real discrimination.

Do you really believe they don't want us in earth , that's why they can not/don't find the cure or is it really difficult???

I cannot believe with such technology and science improvement that they cannot find it fast and safe!!!!

With all this , I cannot enjoy my life... All the time I am afraid if I lose my job, if siblings learn this, if colleagues or friends learn about my status... because then I'm pretty sure they will marginalise me...
And most they will out in margin my son or generally my family...
What the f@@k????
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 05:24:54 pm
“The CAPELLA results are exciting as they demonstrate that an undetectable viral load is achievable in a patient population that has typically had challenges with viral suppression over the course of their journey living with HIV,”

https://www.fiercebiotech.com/biotech/ias-en-route-to-fda-decision-gilead-s-long-acting-drug-keeps-hiv-down-patients-at-end

So by this I understand well???
Almost all or all , will we grow resistance to some or more of art classes in our hiv journey , generally???

So maybe we will ran out of choices I 10-20 years??

Jim am amI crazy or rational?
Because with 48 millions I think now I will fail to suppress my high viral load so I will grow resistance to integrase inhibitors which seem to be very effective for naive or/and heavily experienced patients....
.I'm so scared

Ouffff
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 05:37:56 pm
When first-line therapy fails, second-line therapy may be complicated by drug resistance and side effects.

https://www.nejm.org/do/10.1056/NEJMdo006101/full/

Should or shouldn't I be so worry again now with 49 millions of copies VL per ml???

Please 🙏 tell me if this will not happen to me...
Maybe tomorrow I will know my VL @t 4weeks after starting treatment..

Hugs , brothers
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 22, 2021, 06:13:43 pm
Quote
Almost all or all , will we grow resistance to some or more of art classes in our hiv journey , generally???

No.

Quote
So maybe we will ran out of choices I 10-20 years??

Where does that thought come from?

No, I've already explained you could live for the next 50 years or be hit by a bus tomorrow and I've known some people who stay on a single combo for decades.

If treatment itself caused resistance and we ran out of options within 10-20 years of starting treatment most of us would be dead a long time ago including me.

Quote
Because with 48 millions I think now I will fail to suppress my high viral load so I will grow resistance to integrase inhibitors which seem to be very effective for naive or/and heavily experienced patients....

No, and your VL is not special. Plenty of us had higher and lower CD4's and we are still here. If i recall correctly the highest viral load ever recorded was over 1 billion and that person is doing fine with treatment as well.

I will find the link for that later tonight and update this post.

What you should so is to find out what your VL is after the 4 weeks of treatment so far since they did take your bloods to see if it's heading in the right direction. If within 6 months this treatment does not suppress the virus you could look into switching and that is not a scary thing. Most people switch a few times to find a combo that works for them with minimal or no noticeable side effects.

https://www.europeanpharmaceuticalreview.com/article/143332/the-current-and-future-landscape-of-hiv-treatments-and-vaccines/

Current HIV therapies
“The main focus of HIV treatment to date has been on antiretroviral therapy,” said Forkin. She explained that antiretroviral therapy does not cure HIV, but instead suppresses the virus and slows down its progression in the body, thereby preventing opportunistic infections and AIDS-related deaths

So this "slow down" means it's (ART) only makes the progression to AIDS slower, or can we really stop progression if we can suppress the virus to undetectable?

You are misreading this. You already have AIDS from my point of view, no way you are acute infection (Don't care what you claim).

What matters is the meds will suppress the virus and your immune system will "heal" and recover a great deal. As explained you could live for many years long a and healthy life. You are newly diagnosed in 2021, not in the 1980s. Even compared to the late '90s or 2000's so much has changed.

Quote
I understand Jim who in my eyes seems a bit more stric with me (🤗🤗🤗 joking) but he wants to be realist.

LOL  ;D
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 22, 2021, 06:36:07 pm
Quote
If i recall correctly the highest viral load ever recorded was over 1 billion and that person is doing fine with treatment as well.

I will find the link for that later tonight and update this post.

Yup, over a billion viral load recorded and published in 2015.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680573/

Quote
The patient had a good response to therapy. After 1 month, HIV viral load fell to 7420 copies/mm3 and CD4 count was 38×106 cells/µL. At 6 months, HIV viral load was undetectable (<40 copies per mm3) and CD4 count 287×106 cells/µL, and raltegravir was stopped. After a period of outpatient neurorehabilitation, the patient's memory and cognition significantly improved and currently, 1 year on from her diagnosis, she lives at home alone, independent with activities of daily living.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 06:46:57 pm
Thank you Jim.

Please explain me this...just for informational purposes and make me understand better..

By this :
"You are misreading this. You already have AIDS from my point of view, no way you are acute infection (Don't care what you claim"

Are you believing that I have already AIDS because of my numbers VL49 cd4s-167 on diagnosis or do you believe I had it longer period but didn't test before?

Because : February I was negative..3rd elisa
I had sex with my wife last time before I was infected.before 28 of April.
And with my polish girlfriend .
Both girlfriend and wife are now negative.
The only sex I had was with these two women who are now negative and this pornstar trans woman in April...28of April.
Had illness , an acute illness with fever, sore throat, like flu for 10days after exactly 3 weeks.
At that time I was negative in hiv antibodies by both 3rd and duo tests.
4th gen duo test was reactive to antigen only.

My hive specialist doctor told me after asked me how many WBC I had generally in my life.

We supposed after questions that I might had 500-600 cd4 before infection , so it's totally normal a very deep dive at 1/3 count during acute phase as well as millions of VUral load.

He told me I have no aids. It's just the acute phase because with Elisa 3rd gen I was negative.
And aids and acute are similar to numbers.

So if you tell me it was aids because of numbers , I understand you but I am a bit more scared.

If you believe it was/is aids because maybe I have it for years to have these numbers and counts...I'm telling you for sure it's not the case...

Thank you my friend
For everything , I appreciate
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 22, 2021, 07:00:28 pm
Look, I've already told you that you don't want me to start poking holes in your story about your infection as I will and it will not end well. What you just posted does not help you. So don't go there.

Anyhow, moving on, your numbers are below 200 and is an aids diagnosis (depends on who's standard you use as explained).

What matters is you have started treatment and the meds will suppress the virus and your immune system will "heal" and recover a great deal. So try to relax, give the meds time to suppress the virus and see how things trend over the next 6 months.  ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on July 22, 2021, 07:12:53 pm
I had other stuff I was writing up but I decided to erase it all and just repost Jim:

What matters is you have started treatment and the meds will suppress the virus and your immune system will "heal" and recover a great deal. So try to relax, give the meds time to suppress the virus and see how things trend over the next 6 months.  ;)

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 22, 2021, 07:53:03 pm
Look, I've already told you that you don't want me to start poking holes in your story about your infection as I will and it will not end well. What you just posted does not help you. So don't go there.
I really don't have problem to talk about this. I trust everyone here. You make me feel better. I feel all you as family. I don't have reason to hide nothing. I'm clear and I can tell everything true.
Just ask me..
And please , like talking to my brother, why do you think IT WILL NOT END WELL , OR , WHAT I JUST POSTED DOESN'T HELO ME?
I'm really curious.

Quote
Anyhow, moving on, your numbers are below 200 and is an aids diagnosis (depends on who's standard you use as explained).
Let me please again ask more clearly my question, because I really don't understand a lot because I'm new in this field.
Regardless the previous question of mine to you, and your related answer, my clear question is this ..
Because I know the truth , and for me is exactly what I tell you, I would like to know what is the reason which makes you tell me is AIDS?
Do numbers alone (167cd4 & 49millions viral load) determine the stage of illness?
Because if yes , I am totally confused , because I talked with my specialist believing the same, but he told me , in your case you are lucky to find it during acute phase , that's why your numbers are like that, and it will never progress to AIDS because you started treatment immediately after acute illness.

If you believe is aids because you think I had it for years , Incan understand you!!

So, do you think I have it already for a long time , and this is what makes a definition of AIDS alongside my numbers ?
oR
Bad numbers , anyways, always define what stage is someone in ?

So I mean, can some people go immediately from infection and acute phase to progressed aids??? skipping latent phase???

Quote
What matters is you have started treatment and the meds will suppress the virus and your immune system will "heal" and recover a great deal. So try to relax, give the meds time to suppress the virus and see how things trend over the next 6 months.  ;)
I agree with you. This matters most
However my hiv specialist doctor told me that for my baseline viral load maybe I need a bit more time to suppress bit or we did fail in our purpose...

Thanks both Jim and Leatherman.
Have a good night my friends
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 23, 2021, 12:42:17 am
Quote
Generally, there are 4 stages of HIV infection, but it's a tad misleading as you can go skip stages going to stage 4 sooner.

Advanced HIV disease (AIDS) when being diagnosed most commonly (I think) would be defined as a CD4 cell count below 200 cells/μl or the presence of an AIDS-defining illness regardless of CD4 count.

In the USA, the CDC's definitions and stages are slightly different:

People receive an AIDS diagnosis when their CD4 cell count drops below 200 cells/mm, or if they develop certain opportunistic infections.
https://www.cdc.gov/hiv/basics/whatishiv.html

Just to add, don't focus too much on definitions etc., It's relatively pointless, so instead, just see your first results as a starting point and now you are on meds your follow-up appointments will show the trend. The journey and trend in your labs over the upcoming months/year of starting to suppress the virus are much more important.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 23, 2021, 12:47:20 am
Quote
I agree with you. This matters most
However my hiv specialist doctor told me that for my baseline viral load maybe I need a bit more time to suppress bit or we did fail in our purpose...

I'm not sure what you mean by fail or what is meant by more time.

Anyhow, you should see at least a 90% drop within 6 months of the baseline viral load, if not you might need to switch treatment. I don't see why you would take longer than that expected time and most people would see the baseline start to drop within weeks already but it's not a race.

Did you find out your latest viral load?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 23, 2021, 05:26:20 am
Good morning Jim ☀️☀️☀️☀️
Thanks for all this.

Just he told me , he didn't see again 49 millions. He saw 15-20 millions , so it may take a bit longer to suppress it.

Jim I appreciate all , thank you , and thank you all here for supporting.

I am just afraid , if I skipped stages and went directly to stage4 AIDS , I'm afraid I will have sooner bad illnesses and I will die much sooner.

I have this small yeast infection now... And I'm so scared that all my life I will be having problems..

Jim, should I expect my kidney ( real 90% of one kidney and 10% of the second hurt kidney) will be able to survive these years that you tell me, because of TAF?
I mean TAF seems to be safer.
But anyways in conjunction with emtricitabine they are concentrated to nephrons and in the long run it may slow down...

Anyways.
Thanks.
I'm sorry for asking all the time... I just feel closer to people and not alone.

Thanks.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 23, 2021, 06:20:44 am
Quote
I'm afraid I will have sooner bad illnesses and I will die much sooner.

Quote
You could live for another 50 or 60 years, your 35 now. Depends on what happens in your life but don't smoke, eat healthily and exercise if you want to live healthier and perhaps longer, and considering you are living with HIV take your meds.

Quote
Like I said you could live for the next 50-60 years, you could also be run over by a bus tomorrow. HIV is not an automatic death sentence or short life span, treat it and look after yourself to live a healthier and longer life if you want.

Quote
Look, I've put plenty of easy to digest references and information in the "Just tested positive" welcome thread, I also added things about starting treatment early and life expectancy etc. It' might be useful to have a look https://forums.poz.com/index.php?topic=2276.0

However, don't get focused on these topics.

Quote
you don't have to start planning and preparing your wife & child for your death soon because of your HIV status, and there are plenty of members here with far worse results than your who are doing just fine today.


Quote
I have this small yeast infection now... And I'm so scared that all my life I will be having problems..

Quote
The low CD4 counts mean you are at an increased risk for certain OI's and cancer, however, once the viral load reduces and the body can "heal" the CD4 counts should also increase again with time. Once the VL is suppressed and it will be the CD4 count become somewhat less relevant. That said plenty of people still have low CD4 counts and are perfectly healthy.

As a group we are prone to certain conditions more frequently or sooner in life, that does not mean it will be an issue for you and you will see your doctor or clinic during check-ups to monitor things and treat any issue early.

Quote
Billions of people have health issues, thankfully, you can manage your HIV but it will take medication & time.  You will not have to be having OI's all the time. Meds will suppress the virus, your immune system will "heal" and things will be better. You might feel worse at first given as your immune system starts again and finds & fight things it had been ignoring or had been too weak to deal with but that stage will pass.

Quote
should I expect my kidney ( real 90% of one kidney and 10% of the second hurt kidney) will be able to survive these years that you tell me, because of TAF?
I mean TAF seems to be safer.
But anyways in conjunction with emtricitabine they are concentrated to nephrons and in the long run it may slow down...

Quote
The Descovy combination pill contains tenofovir alafenamide (TAF) and emtricitabine, it's considered kinder on the kidneys than its predecessor (TDF).

However, it's not a conclusion that kidney function will be an issue as a result of TDF or TAF for everyone taking the meds. That's simply not the case, although it can be, thankfully this is included in monitoring so they can switch or change your meds should there be any concerns.

https://www.poz.com/basics/hiv-basics/taf-versus-tdf-difference
https://www.aidsmap.com/about-hiv/chronic-kidney-disease-and-hiv
https://www.poz.com/article/descovy-prep-works-equally-may-safer-kidneys-bones
https://www.aidsmap.com/news/aug-2020/kidney-transplant-between-people-hiv-safe-says-us-study

Quote
HIV Treatment, as explained, is fine and you need it now. Give yourself time to adjust to treatment and keep monitoring things with your doctor. No need to wait with treatment and should your current treatment cause any problems there are other combinations and there will be better treatments in years to come.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 23, 2021, 06:25:41 am
Good morning Jim ☀️☀️☀️☀️
Thanks for all this.


You're welcome.

Look try to stop stressing about stuff that has not happened. Your baseline is just a starting point, its not really relevant anymore as that's the past and you have started treatment now. Focus on taking your meds and looking after yourself.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 25, 2021, 06:40:02 am
What the hell?
Every day is a bit worse.
It's like oral thrush , on cheek , between gums and cheek.
Today I saw additional spot like oval shape 1-2cms far from first.
It's pity because I woke up witvery good mood, and after I saw this I am totally sad, stressed and disappointed that I will live all life like this.

It's not painful but bit strange.
Can you help me?
I had called my hiv doctor at hospital two days ago.
He told me "you didn't see what is oral thrush, and now you take pills and you will not have thrush. It will solve itself"
I send doctor today to see his reaction.
Please help me....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 25, 2021, 06:41:32 am
It's not painful yet fearing and stressing...
Maybe it's expanding inside my organs and I have general candidiasis???
Is it candidiasis..???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 25, 2021, 06:58:50 am
(https://hivcover.co.za/wp-content/uploads/2018/04/mouth-1080x675.png)

I have this , but not in tongue... Yet..
And a bit smaller in surface.

Ouffff
I'm totally scared
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 25, 2021, 07:02:07 am
Hiya,

No reason to be scared, I mean you did not treat it, not sure what you were expecting. So see your local doctor when you can so they can diagnose and treat it. 

Jim
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 25, 2021, 07:27:28 am
Ηi Jim.
No reason to scare?
More additional pills to kidneys..
And if I treat it now.
And if my cd4 rise.
Can I suppose to be healthy for long period (4-6-10months) without something more??
Is it usual?


Doctor , hiv specialist, replied me now.
Don't touch bit or do anything to this.
He will ask when is stomatologist in hospital so I can go and diagnose.

You know what is my problems??
I didn't have any issue without treatment and 48 millions hiv and 160 cd4

I have oral manifestation now with 280 cd4
And maybe with half viral load.

This makes me think I will not live for long ..

Ouf , Jim.. and others.
If I will come in October in Dublin, will go for beer??
I owe to you.
And please send me every since a while to learn about me.
I cannot talk to my friends.

You are my brothers.
🙏🙏
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 25, 2021, 07:31:52 am
Hiya,

No reason to be scared. You were recently diagnosed and your immune system is currently weak, these things happen. Get it treated and move on.

It's not surprising to have some issues when you start treatment, the virus is not suppressed yet and your immune system is still weak but starting to fight things it had ignored as it was too weak before to do anything.

It's a phase, you will get through it and be fine.  Now stop stressing before you hurt yourself.

Quote
Can I suppose to be healthy for long period (4-6-10months) without something more??

You could be healthy for decades at a time, you could also fall down the stairs and break your legs tomorrow or pick up any number of infections just like your HIV negative peers.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 25, 2021, 07:52:21 am
Thank you brother.
🤗🤗🤗🤗

Ouffff...
You relaxed me a bit..

Thanks.
How is your Sunday?

And didn't reply yet.
Can I meet in October??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 25, 2021, 08:20:14 am

Can I meet in October??

Sure, keep me posted on PM when you are in town.

Best, Jim
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on July 25, 2021, 11:47:50 am
Hello gpapadop,
Just like to say I have candidiasis during few weeks before I was diagnosed. If it is candidiasis it is easily treated. Was given a kind of sweet tasting “syrup” & within days it’s gone. Try not to worry. Whatever CD4 currently does now matter as treatment has started. Lots of members here started treatment with single digit CR4. Mine was single digit.
What I have learned is that Dr will check & treat all related issue & treat them if there is any related to low immune (if any). Take it easy & just follow up with your appointments.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 26, 2021, 03:29:02 am
Good morning guys... Hi there...
Good morning virgo313
How are you all there??

Just to inform you.
Doctor called me now.

Blood test , done at 8 of July , a month (28 days to be accurate) after starting my treatment with Descovy and Isentress , showed now

UNDETECTABLE VIRAL LOAD

I LOVE YOU ALL
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on July 26, 2021, 05:27:17 am
I am fine. TQ. Great result. Meds work fast & well.  :)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on July 26, 2021, 09:36:56 am



         ojo.             Hi OP, congratulations!!!, great result…your initial VL level, may have been an error, in any event, you are UD now and you can relax and go back to live your normal life, just take your meds and continue with your doctor’s appointments, you will be OK…again, congratulations!!…hugs.                           ojo
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 27, 2021, 02:27:12 pm
Friends
I am really sorry.

I had diagnosis from ultrasonic for kidneys.

My one kidney is a big bigger to cover my body's needs , the other one is almost lost...
Good kidney : 14,5 cm
Bad kidney : 9cm* 0.7-0.8 cm

How can I live with one kidney only and hiv meds for life...???

Do you know a person living with HIV and one kidney???

I think I'm going to die...

I am not well....

I think all the time that maybe I will start losing my other one kidney with time... meaning that I will start dialysis in some years.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 27, 2021, 03:23:19 pm
Hiya,

As said plhiv can and have even donated a kidney meaning they only have one left themselves.

Jim
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on July 27, 2021, 03:35:58 pm
How can I live with one kidney only and hiv meds for life...???
I'm sorry to hear about the issue with your kidneys   :'(
 
but as far as living with HIV meds, don't necessarily assume HIV meds are damaging your kidneys. The data about side effects shows that most people do not have kidney issues with their meds. (for example, none of my personal friends who have lived with HIV meds for 20-30 yrs. have kidney issues. several have bone density issues but not kidneys). You will have to work with your doctor and the data from your blood work going forward to determine if the meds would be adversely affecting your kidney(s).
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 27, 2021, 04:06:29 pm
Τhanks for your kind support..
I had issue with kidney from when I was born.
Always I had one strong kidney and one just helping a bit.
Now it was first time my doctor of ultrasonic gave a number about minimum width of kidney to 7mm.

Maybe I had the same before because they were writing when I had again ultrasonics , that right kidney is at some places thin, but not giving numbers.

I just ask if you know people living with HIV , with one kidney , with medications art and living more than 20-30yrs.

Final question.
My problem drug is tenofovir. Ok TAF seems to be much safer but don't know with time what will happen.
Maybe it's concentrated and start damaging nephrons or kidney..
Anyways.

I want to know something. I was to Positive Voice team today in Athens. They told me they(Moderna, Scripps etc...) preparing these kind of injections which is not treatment is just messenger to bodies to produce bnAbs ... So it's safer for kidneys...

Ok I know it will need 5-10 years to have this drug, vaccine and that (if all good) will need repetition Avery single a while , months or etc...

I want to ask.
Ok, safer because it's like vaccine.
But isn't it harder for body to produce all the time antibodies to fight all the time hiv?

Maybe safer for kidney but immune exhaustion.
Correct?

To sum up.
Jim I know . I am boring to ask all the time ...
But I was born with problem , and especially me , I should be careful more than everyone.

Now I have almost 1 kidney which. Works 90-95%...and one damaged working 5-10% max..
Should I expect to live enough with one almost kidney and HiV toxic art treatment???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 27, 2021, 04:06:55 pm
I'm going to sleep. I work early morning.
See you.
Buy guys
Good night
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 27, 2021, 04:09:17 pm
My mom is 67.
She told me she could give me if I need kidney.
My wife too.
Should I have transplant now? Or when need?
Because if I need in 10 yes, my mom may be not here... God only knows...
Ouf I'm so stressed...
Kisses hugs
Goodnight
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on July 27, 2021, 04:17:42 pm
Quote
Should I have transplant now? Or when need?

You might never need one.
As said there are other PLHIV who have only one kidney and are fine.

Stop stressing! Look after the good kidney, take your HIV meds, see the doctor for a check-up every six months and live your life. ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on July 27, 2021, 08:18:44 pm
My mom is 67.
She told me she could give me if I need kidney.
My wife too.
Should I have transplant now? Or when need?
Because if I need in 10 yes, my mom may be not here... God only knows...
Ouf I'm so stressed...
Kisses hugs
Goodnight



            ojo.         Hello there!!!

I, like Jim, stop stressing about something you don’t need now, don’t waste time feeling worried and enjoy life. If you were to need a transplant, then, ask your wife or mom.

I think you mentioned you have a son, be stronger for both of you, don’t worry until you have something to worry about. Listen, I was diagnosed with aids in 1994, cd4=20, I kept working 10 noirs a day, six days a week, I even bought my house, I never thought about the future and, I’m still here, even being legally blind, writing to you, maybe with some mistakes but I haven’t giving up, I will keep sharing my story on these forums (English and Spanish) because I made a promise to TONNY, a member of the Spanish forum who died of lymphoma due to AIDS.

About your kidney and antiretrovirals, I’ve been taking meds, the most toxic of all and I haven’t had any juguete’s issues at all, I had páncreas issues with KALETRA, I stopped taking it, problems went away…well, I hope you focus in being UD, enjoy your family and keep living, it’s all I can add hoping to help you understand that life goes on, with hiv, kidney problems, being legally blind, we are still alive and think about those, like TONNY, didn’t have the same opportunity, to keep fighting and being alive…good luck and I hope, your next post is to celebrate the good there is in your life, treatment, family, etc, etc.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 28, 2021, 02:13:55 am
Good morning..
Thanks all for your support.

I will see...I'm a bit stressed.
Because I have some minor pains but without ultrasonic to show some small stones...so...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on July 28, 2021, 01:05:26 pm



            ojo.           Hi OP, well, I’m not a doctor but, if you think the reason for your pain is the small stones, drink lots of water so they do through with the urine stream, I think is all you can do about it. Talk to your doctor what can you take for pain, I think for your kidney‘a problems it’s best to take acetaminophen.

Picture this, when I made participate my family about my status, I had not other chance because I was dying of PCP, I decided to hide my pains and discomforts so my family would not be worried about me, because they feel worst than me if they would know I’m suffering and they couldn’t do anything for me, do you know what I’m trying to say?, English is my second language. Nowadays the only pain I have is neuropathic pain and pain in my blind eye, I’m thinking in removing the eye to stop the pain, and I don’t take meds for my neuropathic pain, I have learnt to live with it…I hope you get my point and enjoy your life, the sooner the better , you will feel better and maybe, you won’t even feel pain because your mind will be busy doing something good…best of  luck and please keep us posted at least until you learn to live with hiv, because are usually tell some of the members who reach  an UD level, to go back and live they normal life before hi which means, even visiting these forums…hugs

Ps well, once and a while we would like to know how you all are doing.                 
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on July 30, 2021, 03:35:00 pm
the thrush that I couldn't see deep down in my esophagus left scar tissue that can cause me issues when swallowing

Hello there..good evening..
How are you?

Still there my like thrush. It changed a bit icon..

But my question is..
How could you notice your esophagus thrush if you couldn't see down there?
I mean if we only have in esophagus , then how can we know if we don't have in mouth??

Mine, scares me a lot...


Also , last two three days I have some small pains or discomfort from my kidney(s)...
I'm so scared that meds art cause slowly problem to my kidney and nephrons of its, ...
Anyways I'm so scared
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on July 30, 2021, 04:07:56 pm



              ojo.          Hi there, if you were to have more thrush inside, you would have problems swallowing, if it is getting better where you can see that means that it is getting better all over your throat…talk to you doctor about those pains and please relax, I think you need to take it easy…hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on July 30, 2021, 09:09:04 pm
I mean if we only have in esophagus
that's not how it works. thrush starts in the mouth and when severe can spread down into your throat. You have to be really sick (very low cd4) and the thrush has to get really bad before it effects your esophagus.

You know, looking back, I feel I shouldn't have even mentioned all this stuff about thrush to you. I really only retold my story to impress on you the need to have a doctor check it out soon, so you could get a medication if needed. If I knew you were going to keep worrying so much about this, and in all the wrong ways, I would have not posted anything.

I know this time has been very scary for you but you would be best served if you tried to take the advice many of us have given you - quit worrying so much and imagining the worst.

You're already undetectable and have a cd4 that is at least 280. (I've lived nearly 20 yrs of my life with counts just like that and I am very healthy.) While it's easy for us to say "don't stress", and it's very hard to follow that kind of advice, you should really try to relax some. The meds are clearly working, and your immune system is getting back to strength.

Right now, you're in a recovery period (recovering good health after HIV has been damaging your immune system) and unfortunately, recovery always takes some time. Just breathe and take your HIV meds every day. Don't read anymore about any of your symptoms and let nature and your meds work for a while.

Spend some time doing something you've always wanted to do. Make sure to let those around you know how much you love and care for them. Enjoy being alive today - and worry about tomorrow later.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 02, 2021, 11:58:36 am
Ηello guys , good evening..
Thanks for your time and interest.
I just think of it. I'm not totally fearful but this is something that with medicine will go away...

Believe it or not, I drank a lot of soda bicarbonate diluted in water and it's a bit better... You know soda is very good for neutralising pH and killing fungus etc...

Anyways.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 02, 2021, 12:02:32 pm
Anyways my problem is different.
Kidney.

I had ultrasound. I see that right kidney is much smaller than the good one the left one.

But this good one, although I have normal blood tests on exams done in one month of starting art, now almost two months after initiation of art I have more and more kidney pains.
I know I have to lose some weight.
But this worries me a lot.
I sent message to my hiv specialist doctor from hospital.
If art creates problems to kidney , how can I understand???
Even if my tests are normal should I continue taking these pills? Or I need to change scheme???

Has Descovy been associated with kidney problems??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 02, 2021, 01:48:33 pm
Please help...
I now took results from blood tests , being done 20 days after my WBC was 5600 and cd4 276. This was 9July.

A day before I had covid 1at dose vaccination
8 july

Today , took results of 27 July with
WBC 3800

What the fuck???

Elevated urea acid. = 8
A bit elevated creatinine = 0.97

Ouf ....what the heck?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 02, 2021, 01:49:45 pm
I destroyed myself...
I cannot live like this...
Kidney , low counts , pills , waiting cancers....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on August 02, 2021, 03:28:18 pm
Please help...
I now took results from blood tests , being done 20 days after my WBC was 5600 and cd4 276. This was 9July.

A day before I had covid 1at dose vaccination
8 july

Today , took results of 27 July with
WBC 3800

What the fuck???

Elevated urea acid. = 8
A bit elevated creatinine = 0.97

Ouf ....what the heck?

Take a deep breath, and count to ten.

Next get an English dictionary and look up the meaning of: "A bit elevated"

Next count to 30 and contemplate on what you read in the dictionary.

If you were realy dying, don't you think that your doctor would have called by now ?

One other question I have for you :

What are you doing ? Do you have a medical background ? ....don't think so ! There is shitloads of medical information available on the internet. Has the coin not dropped with you, that unless you have a medical background it's impossible for the lay to connect the dots ?

You are being treated by a doctor. He knows your medical background. He has all the immages of Xrays and Mri's and your lab results. Only he can connect all the dots AND prescribe the appropriate medication. If your current meds are causing unnecessary harm to any of your organs or health, he WILL act accordingly.

You need to reset yourself asap....get a referral to a psychologist or ask your doctor for help. Otherwise this hyper stressing will on the long run cause you more harm than hiv itself.

Take care and goodluck
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 02, 2021, 03:45:51 pm
I said it before, and I'll repeat it: you will hurt your health if you keep stressing like this.

Your labs are slightly off at the moment.  I'm not surprised, considering you had low counts, only just started treatment and to suppress the virus.

There is no need for doom and gloom over a snapshot lab result as they change and vary. Your doctor should be providing a clear context of what these results mean in a way that is easy to digest and monitor the trend with you and advise you as needed about any necessary changes in the future. Do make sure to let your doctor know about the pain, you have mentioned this a number of times and what you should be doing is letting your doctor know.

Try to relax and stop googling everything. I also agree with Grasshopper about letting your doctor know about what seems to be a constant state of anxiety so they can medically assess that, assist you or provide you with a referral.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 02, 2021, 04:08:00 pm
Thanks guys...you are right.
I have to stop googling.
But , after a month of art initiation I started to show good lab tests , I took hope , I went for holidays in a way that forgot a bit about illness...
So now I'm worrying if there was a hiv Rebound and that's why WBC again to 3800...
What the heck?
Anyways..
I started this period going to beach almost everyday, eating a lot of meat...so maybe this lifestyle which makes me tired , cause this drop in WBC. ??
I mean I forgot illness and started again going out all the time...sun (ok with sincere, protection etc) but...not staying home and resting..
Ouf what the .. is this bad virus.??

My friends I don't want to live with such a virus , it's like a monster inside me , eating me....
Ouffffffff
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on August 02, 2021, 08:00:16 pm
You have mentioned your kidneys many times, I don't see your issue. Your creatinine levels are normal and better than mine. As others have said, stop stressing, you will only make yourself sick from worry. Take your meds, live your life.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 03, 2021, 03:47:21 am
Good morning guys... Yes, you have right.. it's not easy to not stress .. I feel some discomfort in my good kidney. If it fails I have to start dialysis , meaning 4-10 years more life...i.e 39-44 dead...
How shouldn't I worry...?
Easy to say hard to do, unfortunately.

Please my brothers...
Do you know?

After being undetectable within a month of art initiation, I felt well started doing many things again...
Maybe , is this the reason that WBC fell again???
I mean being tired and many things ...???
Talk to me please about your lifestyles..
Is too bad that I am doing almost three jobs??? From health perspective??

Secondly, does anyone know about any Descovy case that caused kidney injury?
Because all the time I am reading about the kidney project, you know , the artificial implantable kidney..
Should I hope I will get one??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Matths on August 03, 2021, 07:38:13 am
Good morning my friend, like many others I have read your communications with great interest. It looks like you are on a good path to recovery having excellent medications to effectively treat HIV. As everyone here said: take your medicine, don’t skip a dose and see your doctor for your appointments.

Let me add one advice: we are here a group with very diverse backgrounds and life situations. And in the midst of diversity we all share one common theme: being HIV positive and sharing with each other our experiences to help each other. That includes you now. We are here to help. The one advice: it appears to me that your fear of various illnesses goes beyond what is reasonable. You should seek help and sit down with a professional therapist to address those fears. It will support you, your family and friends and will allow you heal faster so that you can do what we all encourage you to do: live your life! Best Matt
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 03, 2021, 08:21:36 am
Thank you all... really....

Something more my friends.
Generally, with medications, is it very bad or isn't good to run two three jobs and for everyone who asks help or coffee?
I mean friends need some help, they argue if I don't help. But this time I was needing to rest my body for example after beach...
Or working on too many things... isn't bad for not letting body to heal immune system??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on August 04, 2021, 08:44:36 pm



          ojo.          Hi again…listen my friend, I think that working 10 hours a day six days a week while living with AIDS (zero cd4), saved my life…I think, you need to keep yourself busy, it would help you to keep your immune system working and, at the same time, keeping your mind and sanity occupied and no thinking about hiv or kidneys that often. Your body will let you know if you need some rest…again, good luck and maybe you should consider to look for professional help to help you with your anxiety…hugs.       
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 07:05:28 am
Hi guys.  How us your Saturday going??

I'm inn the beach with my wife ..
Kisses from here.

I want to ask something.
1 month of art , I went from 2800 WBC and 170 cd4 to 5600 and 280cd4
2months of starting art , 3800
2months + 1 week again 3800 I didn't count cd4

I'm also having small very small lymph bul a but enlarged in my both sides of neck.

So I'm worrying if hiv vl grew up again or cd4 decreased in number.

What about covid vaccination? I had it first dose in one month after starting art treatment.
Maybe my body still creating covid antibodies that's why this happened???

I read on net that when we plhiv vaccinate , VL increases generally with every vaccine.

Can anyone explain if this is true and why does it happen?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 07:12:09 am
https://www.hindawi.com/journals/dm/2013/276547/

In the study reported by Ramilo et al., which studied HIV-infected children, it showed that 5 of 15 HIV-1-infected children who received influenza vaccination showed an increase in HIV viral load up to 150% after immunization and 4 of 15 patients showed that the HIV viral load returns to baseline level within 6–8 weeks ...
https://www.hindawi.com › journals
Immune Activation and Viral Replication after Vaccination with an Influenza A ..
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 07, 2021, 07:14:32 am
Hiya.

Even if you're VL slightly blipped post a vaccine it's not an issue at all. People living with HIV are recommend to get certain vaccines and I've see no large scale scientific evidence to contradict this or indicate an issue. (Will post links later)

Also, your healthcare provider, the WHO, the CDC would not be recommending and vaccinating you if it was an issue.

See your healthcare provider about the lymph node, stop googling and looking for issues.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 10:07:00 am
Thanks Jim
Yes I agree to not Google so much, but for informative reasons it would be nice to know what happens after vaccinations.... Is it normal that one month later my WBC lowered a lot, and maybe a viral load a bit increased?
I haven't measured at two months...
They will take blood from me at 23 of October. 3 months after the first measurement.

I'm only afraid to not build a resistance to these good pills that I took , which made me undetectable within a month..
Today I have second covid vaccination with Moderna.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on August 07, 2021, 10:47:52 am
1 month of art , I went from 2800 WBC and 170 cd4 to 5600 and 280cd4
2months of starting art , 3800
2months + 1 week again 3800 I didn't count cd4
. . .
So I'm worrying if hiv vl grew up again or cd4 decreased in number.
in your numbers you list "WBC", which is "white blood count" not HIV viral load. Are you confusing these numbers? As far as concerning HIV, the important numbers are: HIV VL, CD4%, CD4 Absolute.

I'm also having small very small lymph bul a but enlarged in my both sides of neck.
quit touching them. I can't tell you how many times people have posted here about lymph nodes in their neck. to be honest, just like you (and everyone else) never had your cd4s checked before being diagnosed with HIV, I bet you never touched or even thought about you lymph nodes before now. But now in "unrealistic worry mode", you're actually looking at parts of your body for the first time and analyzing these parts based on vague notions of what you think they should look or feel like. Did you know that pushing on the lymph nodes in your neck can irritate them? and, yikes!, enlarge them.

Check with your doctor about your lymph nodes if you're concerned.

What about covid vaccination? I had it first dose in one month after starting art treatment.
Maybe my body still creating covid antibodies that's why this happened???
why "what" happened? your lymph node might have been slightly enlarged for the first 24 hrs after a covid injection. HIV viral load would not be affected at all. WBC could slightly increase 2-4 wks after the injection as the response to producing antibodies

I'm only afraid to not build a resistance to these good pills
you're worrying about more stuff you need not worry about. resistance to medication can only happen if you are not adherent to taking daily meds. If you take them haphazardly, it could happen; but taking meds every day doesn't cause resistance.

I posted this just the other day to someone else about resistance:
resistance can develop when the amount of medication falls below the optimal level to keep the virus suppressed. Normally we take daily meds, which keeps the level of medication high enough to stop HIV from replicating. As we have reservoirs of HIV in our system which can occasionally activate, daily meds keep suppressing this HIV from gaining a foothold.

If however a person falls below 95% adherence, but continues to take some meds, the med level drops too low to be effective. Imagine someone simply stopping meds. At some point there aren't enough medications in their system to suppress HIV and it can once again begin to flourish. Most of the time, this doesn't result in resistance. However imagine someone skipping a day here, a couple days there, and that's where problems begin. With no meds HIV can flourish; but with some meds in their system, but at too low a level to be effective, HIV can mutate against the meds. That's resistance. From then on, even if the patient goes back to being 100% adherent, HIV isn't suppressed by that med anymore.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 01:20:15 pm
Thank you Leatherman. Good evening.
😊😊😊Yes I know what WBC stands for.. but also cd4 is linked to WBC as a percentage of it

Anyways it's strange
0 days off treatment , 2800 WBC , 49 millions VL , 167 cd4
29 days - covid first dose vaccination
30 days , 5600 WBC , UNDETECTABLE , not touchable lymph nodes in neck , 276 cd4
52 days - 3800 WBC
60 days , 3800 WBC , touchable lymphs but not as swollen as in primary infection.

Isn't strange to have lowered WBC even when I have suppressed vl.
If you read on the article in my previous message, It says somewhere is normal to have a pick up in viral load after vaccinations generally...

Ouf , I want to have normal WBC (also cd4) to feel safe ...from cancer, because I have cd4/cd8 equal to 0.4
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 01:41:13 pm
A decrease in white blood cells may be the result of HIV medications (like AZT or ganciclovir), a minor viral infection, or a major opportunistic infection like tuberculosis. CD4 T-cell lymphocytes are a type of white blood cell that HIV preferentially targets and infects.

https://www.verywellhealth.com/white-blood-cell-counts-hiv-tests-49353

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 01:43:18 pm
I'm really worried...

When I was able to recover WBC from 2800 to 5600 , why now I dropped to 3800 and cannot increase again??

It's really problem.
I want to know the reasons.
Shouldn't I???
So I can know what to be careful , what to avoid and what to do as a lifestyle so I can protect and keep immune system in a good position??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 03:28:09 pm
Another thought I have now is this .
About this oral thrush that I have last three weeks and it started around 5 days after first dose of covid Moderna mRNA vaccination, which was 29 days of initiation ART.

I am still having this oral thrush.. a bit closer to front teeth now..seems to resolve the back position and it came a bit more front ...

Can this thrush makes my WBC to drop a bit , when it remains untreated???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on August 07, 2021, 03:30:26 pm
What did you do with the advise some of us gave you earlier = to make an appointment asap with your doctor and a psychologist/counselor to adres these questions/issues ???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 04:37:45 pm
Hi thank you...

Appointment with doctor, for what exactly topic?
Lymph? WBC? What?

You gave right , I must do something with my mental health...
But please , really tell me !!!

How can I be well mentally???

Look ..

"HIV treatment is highly effective. Many people's CD4 count will start to climb after starting treatment. Long-term HIV therapy can result in your CD4 count returning to the expected level for your age. Once your CD4 count improves, with continued treatment and care, your life expectancy is very good.

Other factors, such as age, viral load, genetic make-up, lifestyle and quality of health care will also affect your future health and life expectancy.

After starting HIV treatment, some people’s CD4 cell counts do not increase, or rise very slowly, even though their viral load is ‘undetectable’. This can mean they are at greater risk of becoming ill and of dying of HIV-related illnesses. They may also be at greater risk of developing heart disease and cancers.

If this is the case, it is very important that you receive careful health monitoring so that any developing health problems can be detected and treated early.

Your lowest-ever (also called ‘nadir’) CD4 count may have an impact on your long-term health, even if your immune system has since recovered. Current data suggests that having once had a very low CD4 count is associated with a slightly higher chance of developing some health problems in the future.  "


-My lowest nadir 167cd4...
-some people’s CD4 cell counts do not increase, or rise very slowly, even though their viral load is ‘undetectable’. This can mean they are at greater risk of becoming ill and of dying of HIV-related illnesses
-

These are my case..
So please...
Right me your thoughts....

I'm really thinking there is not reason to live , if I know I cannot reach 60 - 70 years, that I will have earlier hiv illnesses and cancers and sarkoma kaposis and tuberculosis and I cannot do nothing to recover my fucking WBC and cd4s....

?????so? How can I be fine and feel well???

https://www.aidsmap.com/about-hiv/diagnosed-hiv-low-cd4-count
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Almost2late on August 07, 2021, 08:08:28 pm
Hello gpapadop91, sorry you are suffering through this, but it is really unneccessary.. you already have treatment that stops HIV from doing more harm to your immune system,
giving it a chance to repair itself

-My lowest nadir 167cd4...
-some people’s CD4 cell counts do not increase, or rise very slowly, even though their viral load is ‘undetectable’. This can mean they are at greater risk of becoming ill and of dying of HIV-related illnesses
-

These are my case..
So please...
Right me your thoughts....

I'm really thinking there is not reason to live , if I know I cannot reach 60 - 70 years, that I will have earlier hiv illnesses and cancers and sarkoma kaposis and tuberculosis and I cannot do nothing to recover my fucking WBC and cd4s....

?????so? How can I be fine and feel well???

https://www.aidsmap.com/about-hiv/diagnosed-hiv-low-cd4-count

I had a way lower nadir than you, I was also upset, confused and angry. I had kaposi sarcoma and it went away with the same treatment that stopped the HIV progression.

You ask "how could you feel fine and well?".. if you're not in physical pain and all it really is is you worrying about "what if".. then you need to understand  that the odds are in your favor to have a healthy productive life with medication. Try that and try and be happy.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 07, 2021, 08:28:02 pm
Ηello... Really helps...thanks for this..

But ok , hiv will stop replicating..
But anyways , always I had bad WBC.
4500-5000

I never checked my cd4 before.
But now having low cd4 , and nor being able to increase its number, I will sure have cancer , lymphoma, or something soon...
Already fungus in my mouth didn't resolve yet....
What the hell?

Jim had right. Although I start treatment in acute phase, However my immune was weak already from always , so I had/be aids.

I'm so disappointed and desperate now
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 08, 2021, 02:17:55 am
Look I understand this may feel overwhelming at the moment, many of us have been through the same, you are not alone and this phase of feeling overwhelmed will pass.

Although, I really think you should consider talking to your doctor about how you are feeling and coping so they can help you or refer you to someone who can help with the emotional/mental aspect of digesting this diagnosis.

Quote
But now having low cd4 , and nor being able to increase its number, I will sure have cancer , lymphoma, or something soon...

That aidsmap item you quoted, you are fully misreading reading it or reading/quoting out of context. It's also a very generic article, not a personal forecast or prognosis.

You also have to keep in mind that not everyone in our group has the same circumstances or history, and other factors and health issues play a role such as poverty, smoking, drinking, drug usage, hepatitis and other comorbidities are all factors in things.

The same can be said for the life-expectancy thing that you are stressing about, despite that as a group our life expectancy with modern treatment is near normal.

If you want to live healthier and try and reduce your risks of developing certain issues in life you can, focus on what you can control, take your meds, cut out bad habits, don't smoke, eat healthier, exercise etc. 

Now I've said this before but ill repeat it, when CD4 counts are extremely low we have an increased risk for certain OI's, but once the VL is suppressed the CD4 count becomes less relevant and the risks decline.

Quote
Already fungus in my mouth didn't resolve yet...

It's just overgrowth and pretty common regardless of HIV status, no need to stress but as a few of us pointed out go and get it treated, problem solved.

As for HIV & your lab results, you only just started treatment so give your immune system time and keep working with your HIV doctor.

Jim

p.s I have not added links as I've given them already in this thread.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 08, 2021, 02:21:20 am
Hello gpapadop91, sorry you are suffering through this, but it is really unneccessary.. you already have treatment that stops HIV from doing more harm to your immune system,
giving it a chance to repair itself
I had a way lower nadir than you, I was also upset, confused and angry. I had kaposi sarcoma and it went away with the same treatment that stopped the HIV progression.

You ask "how could you feel fine and well?".. if you're not in physical pain and all it really is is you worrying about "what if".. then you need to understand  that the odds are in your favor to have a healthy productive life with medication. Try that and try and be happy.

Great post and fully agree.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 08, 2021, 02:31:30 am
Maybe you should consider taking a timeout from googling & reading up on any more stuff about HIV and instead spend the time looking after yourself.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 08, 2021, 03:06:40 am
Jim.. good morning.. really helps... Really...
However I have these small physical pains in kidneys but as long as I see normal kidney tests I will be ok...
I just need a safer or alternative treatment than TAF/emcitritabine to feel safe on the long run for my only one kidney ...

However, there are times I feel very well and times I feel very badly that cannot stop googling...

For example , in the morning I heard in a nice video this wise statement "knowledge is gold because with correct knowledge you can have correct choices, which in their turn can give great results"..

What do I want to say?
Doctors don't talk and don't tell us enough things..

All night reading I learned this ..

-Opportunistic infections can cause low bone marrow work..I have candidiasis so it's normal to have some abnormalities in WBC.
-Anemia ( many low indexes : low iron , low Ferritin , low b12 , low vit d, low folic acid) can not help marrow to work properly
And I have this too.

I try to search how for example I can raise folic acid levels?
There is supplement of 5mg but , some CDC articles warn that intake of more than 0.8-1mg per day has been linked to greater risk of some types of cancer...
So you have to take half pill every three or four days...

Why should I have to read so much to auto heal myself?
I appreciate doctors, are our gods now , without them we would feel so unhelped but I want to tell that without correct and enough information by them , it's normal that we feel unsafe and depressed some times...
If they could talk to us more thoroughly , then we would feel more safe left to their hands...

Kisses hugs and wishes for nice Sunday and healthy Sunday. 🌷🌹😘
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Almost2late on August 08, 2021, 04:41:24 am
Maybe you should consider taking a timeout from googling & reading up on any more stuff about HIV and instead spend the time looking after yourself.
And I totally agree with Jim here.

Gpapadop91, you should really consider taking Jim's advice because the very stress you are inflicting on yourself may be doing your immune system harm.. take a break and do something you love.

I myself remember coming out of the hospital after my diagnosis, weak with only 13 cd4's, a bunch of pills and stressed out. I would go for walks in the park and eventually got my strength up to ride my bicycle again, while listening to music. In hindsight, I believe this helped me a great deal.

Leaving this link here for you..
Quote
"When we’re stressed, the immune system’s ability to fight off antigens is reduced. That is why we are more susceptible to infections.

The stress hormone corticosteroid can suppress the effectiveness of the immune system (e.g. lowers the number of lymphocytes)"..
https://www.simplypsychology.org/stress-immune.html
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 08, 2021, 11:01:54 am
It's been 22 hrs after vaccination with Moderna .. I feel holy shit... You cannot imagine , it started three hrs ago.
Slight fever 37,5 , headache , body aches , bone marrow pains , feeling face to be burning....

Is this good? Or not?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on August 08, 2021, 11:15:38 am
Is this good? Or not?
What you're experiencing is "normal" for some people. You'll feel better tomorrow ;)

https://www.sharp.com/health-news/why-the-second-dose-of-covid-19-vaccine-has-more-kick.cfm

Quote
If You Received a Second Shot
Side effects after your second shot may be more intense than the ones you experienced after your first shot. These side effects are normal signs that your body is building protection and should go away within a few days.
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/expect/after.html

Quote
Common Side Effects
The most commonly reported side effects, which typically lasted several days, were pain at the injection site, tiredness, headache, muscle pain, chills, joint pain, swollen lymph nodes in the same arm as the injection, nausea and vomiting, and fever. Of note, more people experienced these side effects after the second dose than after the first dose, so it is important for vaccination providers and recipients to expect that there may be some side effects after either dose, but even more so after the second dose.
https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/moderna-covid-19-vaccine
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 08, 2021, 11:42:21 am
Οufff
I'm dying guys... It's too hard... Maybe more severe than primary infection..
I cannot wait days...
And due to kidney I don't want to take pills if fever is not above 38,5
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 08, 2021, 11:49:11 am
Stop it, you are not dying from the shot.

Drink plenty of water, plenty of rest today and if you feel very unwell call your local Doctor.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 08, 2021, 12:06:57 pm
Jim I am feeling like this.. really... It's so difficult and unpleasant... Having pains in my kidney too... What the hell can this be??
I mean the pain in kidney??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 08, 2021, 12:22:54 pm
Jim .. I don't wanna take everyday pills. Please don't be strict to me... I feel that bad now that's making me thinking all the time the kidney which pains and I think it will fail in some period.

When we are about to take Lenacapavir?
Every six months sounds good.
Will this be alongside ART?

Please understand me why I feel like this... I don't feel well , I am alone at home... I need your companion. My wife left yesterday to her parents where is our son...
I feel so bad alone...
My girlfriend which is from Poland is out for coffee and is not nice that she will visit me in my  familyhome...

Please text me some comments...I need it...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 08, 2021, 06:22:39 pm
About the kidney, you mentioned pain before getting the vaccine as well, the answer really remains that if you are having pain go and see your doctor.
 
Quote
When we are about to take Lenacapavir?
Every six months sounds good.
Will this be alongside ART?

The CALBRATE trial is in phase 2, it's alongside daily ART for now and when it would be available. Maybe within a few years, maybe never outside of treatment for people with resistance.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on August 08, 2021, 07:29:02 pm



         ojo.          @OP…I really feel for you but, as Jim told you before, if you are having pain and you are worried, go see your doctor, please. There is nothing with can tell you so you pain will go away.

As for taking meds everyday, either you take it/them or get more problemas so more pains…we are here for you but we also have lives to live and maybe even more problems that your kidney’s pain, I’m telling you this with respet. Maybe it’s time for you to seek mental professional help, because we can’t heal your physical pain for more kind words we can offer to you…I wish you the best, also, I wish I could talk to you via PM but I’ve been having lots of pain in my blind eye that I’m seriously considering getting rid of it for good…hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on August 08, 2021, 07:48:26 pm
I don't wanna take everyday pills.
don't feel bad. Everyone that takes high blood pressure medications, cholesterol meds, insulin, arthritis, skin issues, psyche meds, pain meds, just to name a few, don't want to take meds every day. No one does. But sometimes you have to if you want to have better healthcare. HIV is just not special anymore. Instead treating it is just like with a whole lot of other diseases - pills every day.   ;) :D
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 11:19:28 am
Hey guys....
Just wanted to inform and maybe take opinions because I may think not correctly...

I was searching about lowering dose of my pills.
Unfortunately , TAF is patented and not available in single pills regimen. It's a single pill but only for Hepatitis B , which theoretically I could break in two pieces so I could take half dose as it happens with recommendations from clinicalhivinfo website for example about the second drug of Descovy the emtricitabine.

https://clinicalinfo.hiv.gov/en/guidelines/adult-and-adolescent-arv/table-7-antiretroviral-regimen-considerations-initial-therapy?view=full

There is stated here , if you have Crcl < 50 ml/min you can take 100mg every day or 200mg every 48hrs.

Anyways , I saw these drugs could control immediately my 49 millions within a month.
So why not maybe decrease a bit dosage of Descovy which contains TAF which has been linked to kidney failures.??

Another thought is to cut with pill cutter at 3 pieces so I can take 2/3s or 67% of the daily regimen of these two drugs.
The insentress which has not been associated with many problems in kidneys I will not do nothing.

I know you will tell me to not do this...

But I wanna ask something.
If the same pill is given to a 59kg human and the same to a 130 kg human, why not to lower the dose to protect my kidneys as much as I can.???
Why not?
Hiv Doctors want to treat hiv. Don't care so much about other problems.

Secondly if it's said in the above website that emtricitabine for example can be reduced, why not tenofovir??
Ok I'm lucky I use TAF and not TDF... But if I can do something more...for example , I think for sure Gilead has put a bit more drug in pill for safety reasons , so if I take a 33% Less and lose weight maybe it can be equally successful but also able to avoid nephrotoxicity.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 11:22:23 am
Something more.

For everyone using Descovy and insentress.

I have several bone pains , and main spinal pain back from pneumons.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 11:24:51 am
About covid vaccination with Moderna three days ago and flu like illness afterwards... Remember referring too many incidents of kidney pains??
Today , after a big pain again in the morning , seems to not having , or one or two times only.

Do you think it maybe associated with clot possibly created by covid mRNA vaccine?
It's said they cause such kind of clots
So could this be possible to be a clot in kidney vaeins? Causing some inflammation?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 10, 2021, 11:35:45 am
Quote
I know you will tell me to not do this...

Is your Creatinine clearance less than 50 ml/min?

Anyhow, the combo you are taking is safe and you are being monitored, the dosage will suppress the virus and if it's not causing an issue so I don't see a need for chopping pills up into thirds and even if you had a problem the answer is to switch not chopping up your pills.

But by all means, discuss your idea with your doctor.

Quote
About covid vaccination with Moderna three days ago and flu like illness afterwards... Remember referring too many incidents of kidney pains??
Today , after a big pain again in the morning , seems to not having , or one or two times only.

Do you think it maybe associated with clot possibly created by covid mRNA vaccine?
It's said they cause such kind of clots
So could this be possible to be a clot in kidney vaeins? Causing some inflammation?

You had pains before the shot and continue to have pains afterwards...
See your doctor about the pain.

Quote
I have several bone pains , and main spinal pain back from pneumons.

See your doctor if you are experiencing pain so they can check for the underlying cause and treat it or switch you to another combo if that is needed.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on August 10, 2021, 12:32:58 pm
Now you are into Cutting pills ???? Reading stuff on the internet and while understanding only a fraction, you feel ready to play doctor ?

Sir...THAT'S the way to go if you want to mess up your body and life.

You are playing with fire, and could end up causing irreparable damage to your body.

BEWARE: Messing with the dosage of your meds, could cause resistance to an entire group of meds.

This is my last response to you. I hope you take the steps needed to get the appropriate/b] (mental) health care.

Good luck and best wishes
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 01:26:55 pm
Is your Creatinine clearance less than 50 ml/min?

Hey Jim, good afternoon.
How are you?

I know , I wouldn't do it without talking with him too.
Just sharing thoughts.

No, yet my Crcl is 95 , currently.
But indeed serum creatinine rose to 0.97 from 0.7-0.8 that was always before.
If it rises more than one in my next measurement , it will be meaning real big problem.

Do you know why I'm so worried?
It's new...hiv, diagnosis, having past history with kidney, its for life, side effects, stigma, vulnerable to other. Illnesses, fear for losing work friends siblings, misinformed people, big viral load in beginning, very low  ok low cd4 count , low cd4/8 ratio, pains in kidneys already, ...
Is all this situation easy to digest and can this be done so fast???

I am also worried because if I have problems from kidneys in next measurements , then I cannot switch to another regimen.

From what I have read, and I mean not forums but medical and governmental websites and organisations websites, this what I take is the safest scheme for my kidneys....

If they don't discover new treatment safe for kidneys soon I will die , because my life means traveling and with dialysis I cannot travel.. my life will be prison... So please give me some time and understanding , and please don't judge me for telling some not normal things sometimes...
I just need my time and you.

Also I have elevated uric acid 8 with upper limit 7 and always was 5-6 , urea... always was 20-25 , now is 38 with limit 50 ...

Ouf....

Wishes for a peaceful night guys...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 01:40:30 pm
You are playing with fire, and could end up causing irreparable damage to your body.
Good afternoon , ...
Although strict enough with your latest comment about leaving your last comment on me, I appreciate your wishes ..

Just feeling I am already with my back on the wall...
Aidsinfogov recommends/not using many meds when initially diagnosed with above 100.000 and for some other regimens above 500.000 vl. I had 100 times more.. 😂🤣😂
And same time 167 cd4.

And as Jim says this is late stage of AIDS.

Also this situation is associated with elevated risk of renal failure...and I have one kidney working 95%. Yet...

So I feel like being with my back on wall , lacking alternatives schemes and vulnerable to everything..
I was about to never have covid vaccination.

After diagnosis I was waiting for a month to have more than 200 cd4 as my  doctor advised and immediately went for vaccination the same day. All around me asked me , how??? You???

Because they don't know now I am vulnerable ...

I am also afraid that I will not be able to use the injectable monthly scheme of cabotegravir/rilpivirine because rilpivirine it's connected with viremia failure when having had > 100.000 vl.

But I don't know if they mean to avoid start with rilpivirine in subjects with VL above 100k or just wait until it comes below 100k for six months and then so you can have it for treatment.

You don't know how difficult is to take my meds when I'm at work working with colleague in same car , hiding my pills , asking going for snack and when he goes to toilet immediately searching my bag to find and  take ..

Anyways...

Hope to injections lasting for six months soon... Before I have reduced renal function.

My best wishes too...

As for mental health care you referred to...I read and understood today...
Common side effects both of Raltegarvir and Emtricitabine are depression and some times ideas of suicide.

Hugs and wishes for all of us.

Buy guys.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 10, 2021, 01:47:43 pm
Hiya,

Were going in circles.

You don't have a problem with your current treatment and good odds you never will.

Take the treatment, stop reading up on stuff as knowledge is pointless without the wisdom or clarity of mind to digest it. See your doctor every 6 months to monitor your labs, stop stressing about irrelevant snapshot results for the moment and that's all you need to do for now in terms of HIV.

In the meantime focus on looking after your emotional and mental health. I agree with Grasshopper and others who have already commented that you should consider getting some professional counselling or therapy to help you.

Now if you really want to improve your physical health make sure to focus on what you can control not what you can't control. Cut out bad habits, stop smoking, get vaccinated, eat a balanced diet, get plenty of rest, and exercise.

Jim.

Quote
Aidsinfogov recommends/not using many meds when initially diagnosed with above 100.000 and for some other regimens above 500.000 vl. I had 100 times more.. 😂🤣😂

Irrelevant recommendation or perhaps better to say a guideline not an absolute vs real-world treatment and care. You took the meds, it worked, VL is suppressed.

Keep taking the meds.


Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 02:29:55 pm
Jim thanks... 🤗
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on August 10, 2021, 04:03:17 pm
And as Jim says this is late stage of AIDS
you know this isn't 1990 anymore right? And that people who get treated for HIV (if your VL is UD then you have reached "successful treatment") don't die right? You are needlessly worrying....but we've all told you that several times.

You don't know how difficult is to take my meds when I'm at work working with colleague in same car , hiding my pills , asking going for snack and when he goes to toilet immediately searching my bag to find and  take ..
good grief! what med(s) are you taking? If it needs to be taken with food, take it with dinner at home. If it can be taken anytime, then take it at home in the morning, or at night, and don't even bother taking your pills to work.

and btw, most people will never even pay attention to you taking meds. no one really cares. And if someone was actually rude enough to ask about them - lie. 8) those could be blood pressure pills, antibiotics, vitamins, etc.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 10, 2021, 05:43:19 pm
Quote
And as Jim says this is late stage of AIDS.

I never said and never would say " late stage of AIDS " If I had, and to my knowledge I never have, I would be extremely disappointed in myself.

You are needlessly worrying....but we've all told you that several times.

Yeah, I agree.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 06:22:26 pm
if your VL is UD then you have reached "successful treatment
Hello Leatherman , nice to see you and I'm happy to feel you close to me these difficult times for me...
Tell that I'm more sensitive, that I'm more scared, I'm not so strong , I don't know what...
Maybe because all my life my mom grew me up by saying "be careful because if you need to take pills you will harm your kidney".
Don't ride bikes because if you fall you will lose your kidney..
Don't drink alcohol...
Don't take supplements..
She had right and I love her because I was more careful but I'm more fearful too....
For example I took protein in my 20-23 when I had body building all time.... Then I read a lot about how much they harm kidneys , and I read this again in kidney.org that when you want to take care of Kidneys and stop progressing CKD you have to be within BMI limits and take 0.8-1.2 max protein gr/kg of body weight per day. And I was taking with one kidney 3gr per day...
But at 23 I stopped....

My friends still take at 36...

Anyways...

About viral load I'm happy...yes....but doctor told me there is need to confirm with the second measurement in 3 months from 1st measurement i.e in 4 months from starting treatment. And again at 7 months.

But my WBC falling from 5600 to 3800 make me think that some Rebound caused this drop.

So we will see... I hope it will be undetectable again.hope.
Because then. I will write all day and night here..
😂🤗😂🤗

Quote
as for taking meds with dinner
As for my work , I don't have standard times and standard position. All time changing. Some times I work early mornings and some times night. Normally I work 7-15 , next day 15-23 , next day 23-07 etc....
Next day free from 07 to 07-15 of next day.

So some times because I take meds 15-20 somewhere between these times , doctor told me no problem to take meds with different times +-2,3 hrs every day. Problem is to lose 12 hrs and again because like this you miss doses.
And my colleagues are really gossipers , not only will ask what pills are these but if they see the number they will Google and then find what is it...

😂🤣
They want to know everything or else cannot sleep at nigh.... really
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 06:29:43 pm
I never said and never would say " late stage of AIDS " If I had, and to my knowledge I never have, I would be extremely disappointed in myself.

Jim , sorry... I was misunderstood by you. I'm sorry. Just wanted to be laconic and used these words. I don't remember exact words but anyways you told me that high vl and cd4 <200 is something like progressed illness..

I don't want to put to no-ones mouth words that didn't say...I'm not that kind of person at all...
I mean it was a reason to feel a bit more stressed to know that really having low cd4 is bad ... And you had right.. what matters most is cd4.  I read in aidsmap.com too....
But me having always low WBC , so consequently even before illness I couldn't have more than 500cd4 when I have always lymphocytes 100-2000max

Anyways thanks for all your help...

Today I had less pains in kidneys. 4-10 times.

After vaccination I had for two days 100-200 times or more , every 1-2mins I had or maximum every 5 mins.
I connect this as having some small clot...this is my explanation.

Anyways..
I will keep you posted for informative reasons for when someone searches for effects on kidneys of Moderna covid vaccine when being treated for hiv by Descovy and Insentress.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 10, 2021, 06:30:52 pm
Anyways , guys I appreciate your time, your help, your interest.
I'm really respectful for your interest. You can count on me when in Greece for everything. Your friend and brother George.
Wishes and hugs.
Good night
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 11, 2021, 02:16:47 pm
Although highly active antiretroviral therapy (HAART) decreases HIV-associated mortality, it does not to completely restore health. Patients doing well on otherwise effective HAART remain at risk for cancer, cardiovascular/liver disease, osteopenia, and other "non-AIDS-defining" events. While complete eradication may never be feasible, a "functional cure" in which patients are able to maintain undetectable viral loads indefinitely without therapy may be possible

https://clinicaltrials.gov/ct2/show/NCT01025427

How can you be optimistic when reading this???
Never cure
No restore of health even when on art
Illnesses like cancers , heart attacks etc...

Ouffff
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 11, 2021, 02:38:52 pm
Quote
How can you be optimistic when reading this???

Extremely and with ease. Without even looking I know what you are reading was studied or published at least 10+ years ago.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on August 12, 2021, 02:01:31 am
How can we be optimistic? Easy, we have no choice. This is the hand fate has dealt me, and you. I choose to enjoy the day that I am living. I certainly don't worry about what may happen years from now. You seem to live your life differently from many of us for now. You will get use to this diagnosis eventually, we all do. None of us are happy with it but none of us can change it. Acceptance.
I suggest you try some mindfulness, I practice it and see others on here do. Stay in the present moment.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 12, 2021, 09:08:41 am
Hello friend... I know there is no choice...
Like death..we will all die. We know this.
It takes time , but if there is a more safe treatment , I will accept it totally. My f@@ng pains every day remind me the Illness.Not the pills.
If there is a better treatment soon, I will be totally ok.
My friend Jim and all of you helped me a lot... really..
Only having to login and see your messages and the contact with you make me feel very nice..or nicer...

Hey friends...how can I send you pics from where I am? I am everyday coming to beach to enjoy my coffee... And I want to share with you moments making me happier than the first days that I was all day at home and watching TV and waiting to sleep early...

As I told you Jim convinced me that I have to accept it like sth simple that we have to take just some pills per day. Good food, enough rest, exercise... That's it.
Ok, I totally agree by time...

If tenofovir will not destroy my kidney , it will be totally ok for me... really .

I am just curious , why so highly leveled scientists didn't yet find some effective yet safe pills??

I saw in. Clinical trials that bnAbs are studied for at least 5-8 yrs already...what th hell? If some of them treated off art for 4-24 weeks some, why don't they give us?
..........
Another topic.
Can you please recommend me any book or do you go to group or private lessons???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 12, 2021, 09:08:57 am
I mean about mindfulness.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 13, 2021, 10:05:51 am
Heyyyy

Greetings to everyone from here...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on August 13, 2021, 07:45:55 pm
I know what you are reading was studied or published at least 10+ years ago.
not only is this an old study but it only had 16 participants - of elite controllers no less.

hey again.  :D gapadop91 I think some of that summary is worded more clinically/scientifically than what you or a layperson might have understood
Quote
Although highly active antiretroviral therapy (HAART) decreases HIV-associated mortality, it does not to completely restore health.
ARVs only stop HIV from replicating. The meds do nothing to "restore health" (whatever that means, as I don't see it defined in this study). Meds stop HIV from replicating which allows your immune system to recover; but the meds don't make your immune system any better. Once HIV is stopped, your immune system recovers all on its own.

If you read it from a clinical standpoint, they're just saying what we already know about ARVs. They don't make a patient's health better; they stop HIV so that a patient's health can recover.

Quote
Patients doing well on otherwise effective HAART remain at risk for cancer, cardiovascular/liver disease, osteopenia, and other "non-AIDS-defining" events.
personally, I find this statement worded imprecisely. "at risk" is the not the same as "might be more susceptible". Smoking puts you "at risk" for cancer; but that doesn't mean you're definitely having cancer in the future. It just means that compared to people who don't smoke or those who have quit smoking, you would be more likely to develop (i.e. to be "at risk" of developing) cancer in the future.

Quote
While complete eradication may never be feasible, a "functional cure" in which patients are able to maintain undetectable viral loads indefinitely without therapy may be possible
A cure might never be found. HIV is a very tough disease to deal with. As I often tell people, if you want a cure faster, you need to learn microbiology and figure it out for all of us. Otherwise we'll just have to wait until someone else figures out a cure. It's easy to be an "armchair quarterback", but doing the science to find the cure is several paygrades above most of us. In the meantime, a pill or two a day isn't all that big of a deal. Many of my friends, who don't have HIV, take more pills than that daily.

Quote
I am just curious , why so highly leveled scientists didn't yet find some effective yet safe pills??
because HIV is a retrovirus which has been incredibly difficult for scientists to deal with. You say "effective yet safe", and I ask "have you read the package insert that comes with your medications? Did you look up the information at the manufacturer's website?" Medications are only approved to go onto market when the amount of effectiveness is high and the negative side effects are low. Reading the information about each med, you can see for most medications that while there may be higher ranges (0% - 15%) of mild side effects (nausea, headaches, etc) there are always lower ranges (usually 0% - 5%) for harsh effects or long-term effects. In effect, this means that 90% - 95% of patients don't experience any side effects - well except the desired side effects of stopping HIV from replicating. ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 14, 2021, 01:47:14 pm
Hey Leatherman... Good evening , how are you??
Nice to find you here...
Didn't read yet your post... Now I'm going to read it...

But before see this please.

I started with 167 cd4
A month on ART I had 276
Look this pic https://www.dovepress.com/cr_data/article_fulltext/s255000/255751/img/HIV_A_255751_O_F0002g.jpg
I had a week after the first Month, i.e at 5 weeks after art initiation some minor oral thrush deep in cheek between gums..
It resolved and it became in front.
Now I have the same minor in the other side ..Same place...but on the left now...
Should I consider that I will never have more than 500 Maximum cd4 according to the above pic?

I'm worried because I found out that having confections, even this small thrush, or vitd deficiency, I also have low folic acid, and low b12. All these make bone marrow to function less...true???
What can I expect?

Because anyways I have low cd4/cd8 ratio close to 0.4 and generally low cd4 count ,both related to cancers...

And ok, you have right bro tell me that I should only look after myself and not things I cannot do nothing with , but if I can do something to help immune and you know from experience , please tell me ...
Thanks 👍
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 14, 2021, 01:58:48 pm

Detailed thoughts..thanks for this....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 18, 2021, 06:49:39 pm
My girlfriend in a general tactical basis checkup found to have 9700 WBC , hiv negative , only some minor thyroid problems she has , and she complains all the time that I have depression , I don't give her enough interest , I neglect her etc....

How much unconscious can a person with perfect almost hygiene and health can be?
She didn't understand yet that having health you are the richest person in the world...

Should I accept complains and explain or do you think it's toxic behaviour???
Generally complains maybe mean that someone does some bad things that's why he/she accepts complains...

But in our position, accepting complains is it furthermore bad for our health???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Matths on August 18, 2021, 07:37:06 pm
You should follow the recommendation that comes from this community: find a therapist. Take your medicine.

You seem reluctant to listen what this forum advises you to do. Instead you circulate around the same issues over and over. Therefore, one last time from me: find a therapist. Take your medicine and don’t miss a dose. Best Matt
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 18, 2021, 09:20:08 pm
You should follow the recommendation that comes from this community: find a therapist. Take your medicine.

You seem reluctant to listen what this forum advises you to do. Instead you circulate around the same issues over and over. Therefore, one last time from me: find a therapist. Take your medicine and don’t miss a dose. Best Matt

Hey Matt , hii , how are you? Wishing you all the best...

I'm sorry but I think I am a bit misunderstood.
I think I didn't talk about this that someone who has his total health cannot compassionate someone without...

For the other issues aforementioned above some time ago , I can understand your suggestion for mental doctor or therapist... But about asking your opinion if having someone in our lives who is not understanding us ...is another topic...

Yes I don't miss doses.
Thanks for your support..
Wishing you all agood night..
Buy hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Matths on August 19, 2021, 08:18:10 am
Hello my friend, when I suggest for you to work with a therapist, I’m not referring to the various topics you bring up. I’m referring to your thinking pattern which suggests you go in circles. You are a master of creating new topics and the reservoir is endless. This prevents you to focus on the one topic that counts most: live your life.

Best Matt
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 19, 2021, 02:37:54 pm
Τhanks for reply..I really appreciate it...but to live my life I have first toml undestand the new situation, to see how it goes so I can have as much strong immunity as I can so I can live my life....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 28, 2021, 05:29:33 pm
Hello guys...
How are you?
I was pretty fine last two weeks that I didn't bother you a lot...
Until today.
I need your opinions please but real.
Because I didn't search on the net.

I was for food with some good friends.
They are old and we'll educated. Meaning about 48-70
The younger one is medical examiner, doctor.

Sometime returning to home we listened to radio George Michael song. He told me he died from aids.
I told I think from heart attack. Because I think his partner had but not him.

Anyways.
He told back... No he had this. And I wonder how Magic Johnson can live for almost 30 years with being carrier of the virus.

I asked : but new drugs can suppress virus.

He told me anyways the delay more the progress to AIDS.
But progress is for granted , slow or fast , whatever pills whatever you do.

And he destroyed my mood.

So I ask you.
With new treatments can we stop progression to AIDS or just delay it from having it tomorrow and postpone it to have it in 15-20-30 yrs???

Sorry sorry , I know....
But his medical profile f@@ked my mood....and optimism.

Good night guys..
Hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 28, 2021, 06:18:13 pm
You already know the answer and I've provided links and references on this topic already.

Your friend is talking rubbish, at best they are outdated.
Forget about what they said and move on.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on August 28, 2021, 08:44:39 pm
Quote
Your friend is talking rubbish, at best they are outdated.
for educated people they are all talking rubbish. Didn't any of y'all have a smart phone for google?
wikipedia told me this about George Michael's health

Quote
struggled with substance abuse....
abused sleeping pills.[187]...
....
October 2011, chest pains , pneumonia and, until 1 December, was in an intensive care unit; at one point, he was comatose.
...
undergone a tracheotomy.[192] After waking from the coma, Michael had a temporary West Country accent, and there was concern he had developed foreign accent syndrome.[193]
...
May 2013, Michael sustained a head injury when he fell from his moving car on the M1 motorway, near St Albans in Hertfordshire, and was airlifted to hospital
...
senior coroner in Oxfordshire attributed Michael's death to dilated cardiomyopathy with myocarditis and a fatty liver

then googling up "Fadi Fawaz", GM's final boyfriend, I found that he was the only one to have said anything about HIV. I learned he said it 3 years later with a lot of other acrimonious accusations ....while selling off George Michael memorabilia to pay off his own overdue debts. That's not a reliable source at all.

about what they said and move on.
I don't know if I'd forget this. Your friends didn't actually know the facts about GM, and made up a story. Then when you actually mentioned the real life events they implied that you were incorrect.... when it was them. Then they told you the wrong medical information about a medical condition that they obviously know nothing about. Maybe they're making up these stories with no evil intent because they're just older guys pontificating about stuff they half-read on the internet or half-heard on the news and only half-assed remembering any of it; but regardless of the reason, you should remember to take important information from them with a grain of salt.  ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on August 29, 2021, 12:02:31 am


So I ask you.
With new treatments can we stop progression to AIDS or just delay it from having it tomorrow and postpone it to have it in 15-20-30
Hugs
[/quote]


           ojo.             Hello again…with all due respect, if treatment were to delay aids, why are you wasting your time worrying, go out and enjoy life, as you said you were doing for two weeks, don’t listen to anyone but yourself, if you are feeling healthy and having fun, so, you are ok, your body will tell you, besides your kidneys, if something is wrong so you will check with your doctor, meanwhile, take advantage of each day of those “15, 20 or 30 years treatment is delaying you getting AIDS”…I, like Magic Johnson, have been living with hiv/aids ( I’m not sure if he ever had an aids dx, ever 30 years with the virus and, I lived with AIDS for five years after my AIDS dx, with only 20 cd4 which means that I was already living with AIDS for at least two years before my dx, according with my specialist…I invite you to live every day as it was the last day of your life, nobody knows when you or I are going to die, I have been doing that, living every day as it was my last day, since my aids dx in 1994, even though, after my doctor told me that I l only had two years to live…just a humble opinion…best wishes.                  ojo                   
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Almost2late on August 29, 2021, 07:13:24 am
When I was first diagnosed in the hospital, I was very naive about treatment for HIV.
I thought exactly how you do now, I was scared and confused.

The infectious disease doctor told me bluntly "You have full blown AIDS",.. and he didn't tell me that the Atripla he prescribed would most likely save my life.
He seemed to be more interested in who I slept with.

Another doctor, a pulmonologist who was treating me for the pneumonia was kinder and gave me better advice.. told me I would be okay.
I'm very grateful for the people who helped me understand and come to terms with living with HIV. But I also realized that some people can't be relied on for good information.

I asked : but new drugs can suppress virus.
Yes, this is true.. you are correct.

He told me anyways the delay more the progress to AIDS.
But progress is for granted , slow or fast , whatever pills whatever you do.

And he destroyed my mood.
He gave you misinformation.
THE OPPOSITE IS TRUE.
Effective medication/treatment helps us progress from an AIDS diagnosis, to a healthier person living with HIV


And this is true for many people on treatment.. don't let them bring you down.
If it weren't for treatment, I would've died a years ago.
.
My numbers at bottom here don't lie. And I'm just one of many examples
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on August 29, 2021, 05:07:05 pm
Thanks all of you...
Really knew this what you told me , just needed the reassurance.
I can really see it goes a bit better by time.
First day I was about to suicide.
Two weeks later feeling some times the same.
Now thinking of this only when feel bad pains in kidneys or when have lower than 4000 WBC.

I know by time we will be better.

But I will follow some other good advice too.
Or mix it.
Imean yes I will live my life everyday as it would be the last..but not really..
I will leave it like that But with careless as Jim told..
Fruits , sleep , rest , happiness , no smoke , no alcohol ...

I feel more confident.
It's t totally right because I like so much whiskey..
I want to drink sometimes a bottle of whiskey with coke.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on August 29, 2021, 05:10:27 pm
The other question you have was answered here: https://forums.poz.com/index.php?topic=75420.0
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on September 02, 2021, 02:12:51 pm
Hi there...

After reading again disappointed end for Imbokodo trial... And also this
"Only some study participants with low starting viral load became virally suppressed when treated with bNAbs" ..

I am a bit stressed again and disappointed and pessimistic.

According to what is written above in parenthesis , I won't have (also many of us here) the same possibilities of some other guys to maybe suppress virus better ..

With 48 millions starting viral load???

https://www.thebodypro.com/article/advances-in-treating-hiv-broadly-neutralizing-antibodies

😒😒😒
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on September 03, 2021, 07:10:37 am
Here we go again....

Are you also a bit stressed and disappointed and pessimistic, that there is no pill or injection available (for anyone !) that will regenerate our cells and prevent death....extend our lives FOREVER till the end of time ?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on September 03, 2021, 05:13:12 pm
I won't have (also many of us here) the same possibilities of some other guys to maybe suppress virus better
My virus has been suppressed to undetectable for 12 years. I don't know how it could be better suppressed than that. Make sure to take your meds every day and your virus will be suppressed too.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on September 03, 2021, 06:27:43 pm
🤗😁❤️😍
Hello there...
Wish you all a happy weekend 😁😜😁
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on September 07, 2021, 11:42:24 am
Good evening guys
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on September 10, 2021, 03:45:04 am
Good morning guys.

Please again some information.

I took today an envelope from hospital and give it to municipality because we take some economic help ..

Itt was written on diagnosis that I was diagnosed with aids stage A3 with HIV b24

Is it so bad???

Am I going to die soon???

I'm sorry but I am stressed again.
Please tell me if I will be ok.
Please

Good morning
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on September 10, 2021, 04:52:42 am
Just take your pills, like millions of others. Read the forum, there are people on here who were at death's door but are still alive and kicking today. You will be fine
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on September 10, 2021, 05:34:48 am
Thanks Dave. Helping but not so much.

A3 is final stage?
What does that mean?
Maybe that's why I had oral thrush ?

I will take my pills.
But please tell me ...
Maybe this happens always in acute phase?
Due to total drop of cd4s and high viral load?

Will I ever be able to recover totally with good pills?
Will I leave more 20-30 years like Leatherman so to be able to see grand children???

Ouf again too much stress....

Or maybe doctor wrote this to justify the economic help from government. Because you take only with cd4 lower than 200 and final stage.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on September 10, 2021, 05:50:34 am
It is just the official technical term in your country to describe your condition on diagnosis. I would not read to much into it. I fully expect you to come back to this thread in about a year's time, read your own posts again, and then ask yourself what all of the worry was about.
Easy to say but hard for you to accept as you are still absorbing the diagnosis. Believe me, the day will come when you don't even give HIV a second thought. The pill you take will be a normal part of your daily routine.

Try not to stress over what Dr's write, especially official paperwork. It would be blunt and to the point just for ease of reading for themselves.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on September 10, 2021, 08:27:07 am
Will I leave more 20-30 years like Leatherman so to be able to see grand children???

Or maybe doctor wrote this to justify the economic help from government

Here's a chart of the CDC classification of HIV. I would note that A3 is not the "final stage".  Untreated HIV resulting in high VL and low cd4s along with an opportunistic infection that has a patient hospitalized could possibly be terminal (meds can and still do save many people even in that dire of a situation) but still would never be labeled "final stage".
(https://i.postimg.cc/x14T7tMr/fig1.png)
(the clinical B column should read "not A or C")
I was a C3 for well over a decade - but for more than another decade I have been an A2

Keeping an official "AIDS" diagnosis (even after a patient has improved) serves two purposes.

1. This data point in your health records gives a notice to any health care provider caring for you to be on alert for how your current health situation might be impacted by you having had a severely compromised immune system. Certain meds, including anesthesia, can be contraindicated for someone who is HIV+ and some health issues may be more likely.

2. The Ryan White Care Act provides for health care, meds, and other services for people living with HIV. Most clinics treating HIV accept lower-income patients by using Ryan White funding. Funding is always based on needs and earnings, so an AIDS diagnosis is one eligibility qualification for patients.

Just as an aside, the big upside to clinics accepting RW funding is that the funding comes with data-tracking and quality requirements. Clinics are required to work towards goals set by local RW quality committees for certain measurements of health. In order words, all clinics accepting RW funds must work towards have specific amounts of HIV+ patients on meds, undetectable, screened for HepC, syphilis, gonorrhea, mental health, missed appointments, timely medical visits, etc. In the spirit of "a rising tide lifts all boats", when Ryan White qualified patients are being taken care of properly, all HIV+ patients (including insurance and self-pays) are cared for better.


As far as living 20-30 years, On Dec 26 I'll celebrate not only my diagnosis; but 29 years of ARVs. In March I'll celebrate not only my 60th birthday; but 24 years since I was lying in a hospital nearly dying of AIDS (for the second time in two years). I haven't been ill from HIV since then, all thanks to the newer meds. With the same body structure and health issues, it's easy to tell that much of my genetics come through my mother from my GrandMother's side of the family. Although the last 6 months have finally taken a huge toll on her health, we just celebrated her 104th birthday. So, even though I've already lived almost those 20-30 yrs you mentioned, I'm really expecting another 20-30 years (or more) from this point in my life.  ;D Really, as long as you adhere to meds, you'll live as long as you always would have based on your genetics and other health issues.

Quote
"A person living with HIV has a similar life expectancy to an HIV-negative person – providing they are diagnosed in good time, have good access to medical care, and are able to adhere to their HIV treatment."
https://www.aidsmap.com/about-hiv/life-expectancy-people-living-hiv

I can't find a link right now but there are articles that discuss how PLWH who have good care and remain adherent may actually live longer lives than others because of receiving better healthcare than those not living with the virus.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on September 10, 2021, 08:54:14 am
Quote
Will I ever be able to recover totally with good pills?
Will I leave more 20-30 years like Leatherman so to be able to see grand children???

I think this question has already been answered by multiple members multiple times within this thread.

The letter is just outlining what you already knew when you were first diagnosed. Nothing has changed in regards to that initial diagnosis and there is no reason to re-panic or re-stress about it.

You are on treatment now, your VL is suppressed, that's it. Keep taking your meds, live a healthier lifestyle if you like. Keep in mind you could be hit by a bus tomorrow or live until you are 90+ years old, plan for the latter.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on September 10, 2021, 11:10:53 am
Hello, hi!
There is no “final stage” of life even with low CD4 & high VL. Once you are given pills, you are as healthy as a normal person because the hiv can’t do any more damage. Just relax & try not to think “what is in your body”. Most important is how are you feeling now? Is the oral thrush gone?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on September 11, 2021, 09:01:47 am
Hi Jim. I see you are online and I'm now reading all posts. I will reply to all. Good weekend 😀
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on September 11, 2021, 03:39:57 pm
Thanks Dave. Helping but not so much.

A3 is final stage?
What does that mean?
Maybe that's why I had oral thrush ?

I will take my pills.
But please tell me ...
Maybe this happens always in acute phase?
Due to total drop of cd4s and high viral load?

Will I ever be able to recover totally with good pills?
Will I leave more 20-30 years like Leatherman so to be able to see grand children???

Ouf again too much stress....

Or maybe doctor wrote this to justify the economic help from government. Because you take only with cd4 lower than 200 and final stag.          Ite.



        ojo.           It was November 1994 when I got my  “FULL BLOWN AIDS” dx, 20 cd4, I started treatment January 95, for five more years after my dx, I lived with zero cd4 and high VL due to treatment failure (I got several OIs,the worse for me, CMV RETINATIS, which left me almost blind, no vision in right eye and tunnel vision on left eye with a bad cornea) and, I’m still here…meds in those day, 80/90s weren’t as good as the life saving meds nowadays, it takes just one pill a day to control and suppress the virus…my point, just take your meds as prescribed and try to live your life, follow your dictors appointments and keep yourself busy, even, stay away from these forums until you have learned how to live with hiv, a crónica condition, and come back when you can share your story to help other newly diagnosed members. I think you being reading us is causing you the oposite effects we, here, are trying to offer to other…my humble opinion…wishing you the best



Ps. I acquired this virus in 1986, diagnosed, November 29, 1994 with PCP therefore AUDS cd4=20

There’s life after an hiv/aids dx, especially nowadays.                                                   
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Bucklandbury on September 15, 2021, 03:02:20 pm
/ deleted

I added nothing new to the conversation, and I apologize for responding in the first place.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 02, 2021, 04:23:23 pm
Hello.. good evening guys. How are you? Are all of you ok?
Wishing you all have a very nice weekend.

I have started to become familiar with chronic pain. I have small pains in all my body. But I understand it's the condition.

See you guys.
Jim Leatherman Dave Virgo Bucklandburry all everyone here hugs and wishes for good life...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on October 02, 2021, 08:34:07 pm
Hello.. good evening guys. How are you? Are all of you ok?
Hello again.  :D
I'm trying to feel better. I've been under the weather for about 2 weeks but I'm pretty certain it's all stressed related. Although, there was no inheritance from the passing of my 104 yr old grandmother, my two younger brothers have both been a pain in the ass with me and mom because neither, of their own choosing, attended the small funeral. While I know it's not my problem, I am the peacemaker and glue that holds my family together so it has really stressed me. But I've come to grips with it being their problem not mine and hopefully my stomach and guts will catch up to the lessened stress and start feeling and being better soon. ;)

I have started to become familiar with chronic pain. I have small pains in all my body. But I understand it's the condition.
What condition are you referring to? hopefully not HIV. "Small pains" are rarely a side effect of either HIV or the meds, although your body can feel more fatigued or "painful" during times with a high viral load or when adjusting to meds.

speaking of viral load, I noticed that you said, a while ago, that your cd4s had gone from 167 to 276. Did you get a newer viral load count too? With your cd4 count over 200 now, reaching undetectable is the next goal to focus on.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 03, 2021, 12:21:54 pm
Hellooooo Leatherman.. I'm sorry to hear your grandmother passed away.. if I understood well. Our condolences to you..
Sorry to hear you have to keep balance in your family but my thought is to keep distance from stressful situations..

Yes I know about stressful situations. I have the girlfriend (which I know for a year and we met each other when I was almost ready for divorce with wife). However wife corrected many of bad behaviours and I don't leave easily a family with a very young son...so gf presses me like nothing...
She has right...she feels alone...but I have right toom. I have my health issue to focus on...

As for next tests is in 3 weeks. 4,5 months from starting art or 3 months after first test.

You have right about cd4 s.

ART initiation 10 June - 167 or less cd4s , 58 millions VL | 2800 WBC
1st test           7July -.     276 cd4 , UNDETECTABLE |.  5600 WBC
Blood general test 4 August - ...no data. -  3800 WBC (maybe because of vaccination) I don't know

Do we have some information about something new or innovation about illness control , possible cure on horizon or better treatment?

Thanks guys.
Good night
Hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on October 03, 2021, 02:26:13 pm
1st test           7July -.     276 cd4 , UNDETECTABLE
Wow! That's excellent! In a short amount of time not only did your cd4s get over 200 but your viral load dropped to undetectable. Keep this up (by staying adherent to your meds) and by 6 months, you won't have to worry about transmitting HIV (U=U; undetectable = untransmittable (https://www.aidsmap.com/about-hiv/what-does-undetectable-untransmittable-uu-mean)). Great job, keep up what your doing with your HIV medications!

Do we have some information about something new or innovation about illness control , possible cure on horizon or better treatment?
right now, they've started using Cabenuva which is a once-a-month injection
https://www.fda.gov/news-events/press-announcements/fda-approves-first-extended-release-injectable-drug-regimen-adults-living-hiv

and the FDA Clears Human Testing of EBT-101 Using CRISPR-Based Gene Editing
https://forums.poz.com/index.php?topic=75593.0

I'm sorry to hear your grandmother passed away.. if I understood well. Our condolences to you. Sorry to hear you have to keep balance in your family but my thought is to keep distance from stressful situations..
thanks for the kind thoughts. While I miss my grandmother, it's hard to be sad when all I can think about is how she lived a wonderful, full life to 104. I'd like to think that when I reach 104, people will think the same thing about me.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 06, 2021, 09:34:13 am
Good evening.

Yes it's fine.. just waiting to see the new measurements in 20 days. 4 months of starting art .

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 06, 2021, 09:44:41 am
thanks for the kind thoughts. While I miss my grandmother, it's hard to be sad when all I can think about is how she lived a wonderful, full life to 104. I'd like to think that when I reach 104, people will think the same thing about me.

Hahah Leatherman ... Let's go there.... because with your DNA you will go to 204 I think so , our grand children yes maybe think the same for you..for sure , not maybe... 🤗
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 06, 2021, 09:47:16 am
EBT-101 Crispr Cas9 technology
 ;D
Guys what about this ?

Do you see any light at the end of the tunnel?

Yes I know., Nobody knows. We just wish and hope.
But I mean..

Does it have any new , better hopes than the Imbokodo trial which failed hard..???

Or are we gonna see soon similar disappointing results here?

Just some thoughts of what maybe you have read..

Good evening
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on October 07, 2021, 01:33:38 pm
because with your DNA you will go to 204 I think so
oh, lordy! I hope not.  ;D  But I'd be fine making it to 108. That would be 3 times longer than when that nice hospital doctor told me so long ago that I was probably going to die before morning.

Or are we gonna see soon similar disappointing results here?

Just some thoughts of what maybe you have read..
can i tell you the same thing I told people 10yrs ago, 20yrs ago, even 30yrs ago?

HIV is a retrovirus and incredibly hard to treat much less cure. It's going to take a lot of time - or perhaps NEVER - to have a cure. So the best option is to simply not stress and worry about some grand solution to HIV, but to take meds and live your life to the best you can everyday. If they finally develop a cure, then you haven't wasted your life stressing; but if they never develop a cure, then you still wouldn't have wasted your life stressing. Of course, I'm not suggesting to not follow the research; just don't let life pass you by waiting on something that might never occur.

I also say one other thing to some people who are adamant that a cure needs to be found - then you need to go into microbiology and help find the cure. The more scientists we have working on the cure, the faster someone will finally figure out a vaccine/cure for retroviruses.

best wishes on your next lab results! I had lab work Tues. and am still waiting for a few results. So far I'm still UD; my white blood cells aren't low anymore; unfortunately my lipids were high (oops. forgot to fast before the blood work); and I don't have tuberculosis (I already knew this but it was a required test for the Ryan White quality program).
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 08, 2021, 04:20:32 am
Good morning there... How are you all??

Tha is Leatherman for sharing byour thoughts. It's true that we really need to hope. This makes us having a motivattion to live...
Yes , you told people 10, 20 , 30 years ago that not... Nothing changed here? After big technology advances? After so much research?

What about this EBT101???

Sure , I must not stress for life and for cure...

I need it because I'm so much scared of being vulnerable to cancers. This is what I'm terrified for....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on October 08, 2021, 08:04:32 am
Nothing changed here? After big technology advances? After so much research?
oh, things have dramatically advanced.

We no longer have just AZT. PLWH don't have to take 15 pills a day with all sorts of time restrictions - every 4 hours, 2 hrs before food or 2 hrs after food, etc. (I used to have to set an alarm to wake up every 4 hrs, 24 hours a days for meds. Years later I had to have a chart to figure out when to take what). We no longer have to take liquid meds because pills hadn't even been made. We longer have to have refrigerated medications. (although I do miss the mylar foam-insulated bags my meds used to come in. I used those silver bags for Christmas gifts by slapping a bow on the outside. Now I have to buy wrapping paper. LOL)

As far as a cure, I believe everyday we get closer. But HIV isn't just a virus; it's a retrovirus. Several other retroviruses cause cancers. Unfortunately, while we successfully treat a lot of cancers, we still haven't "cured" most cancers. (According to estimates from the International Agency for Research on Cancer (IARC), in 2018 there were 17.0 million new cancer cases and 9.5 million cancer deaths worldwide.) Retroviruses just integrate themselves too much into our bodies, and short of killing the patient, it's just very hard to unravel a retrovirus from the system of patients.

If you look through the research forum here, you can see that scientists have been trying to defeat HIV for 40+ years. Every "failure" pushes science forward towards a cure. That's why I suggest people go into microbiology fields. Clearly, it's going to take more time and more people to finally figure out a cure.

Personally, I believe it will be some sort of "kick-n-kill" method (a method to "kick" the latent HIV in the reservoirs into action and then a method to destroy all the HIV) or Crispr will lead to a cure. But what do I know? I'm not a microbiologist; I'm just an almost 60 yr old guy, living with HIV for almost 37 yrs (my HIVaversary is coming up in Nov) who's more worried about my family history of high blood pressure and my rising triglyceride level than HIV.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on October 09, 2021, 01:49:41 pm
Good morning there... How are you all??

Tha is Leatherman for sharing byour thoughts. It's true that we really need to hope. This makes us having a motivattion to live...
Yes , you told people 10, 20 , 30 years ago that not... Nothing changed here? After big technology advances? After so much research?

What about this EBT101???

Sure , I must not stress for life and for cure...

I need it because I'm so much scared of being vulnerable to cancers. This is what I'm terrified for....



              ojo.              Hi there!…I feel for you my friend, I wish you would stop worrying about what could happen in the future because nobody knows it…as leatherman said, science has advanced so much that lots of people take just one pill a day, to me, that’s a cure, specially now that we know U=U, you even can have healthy babies…after I was diagnosed, I used to search for studies and advances for hiv treatments, I felt hopeful, then, I read that those advances didn’t work, I felt even worse so, I stopped reading studies or possible cures, I decided to wait until my doctor tells me here it is, take this, it’s the cure…cancers, after 27 years of taking meds and even living five years, after my dx, with aids, I haven’t had any cancer but, if I were to have cancer, I will take care of it, that’s it…don’t worry until you have something to be worried about, you know what I mean?, English is my second language…I wish I could find the words to make you feel better and convince you that as long as you take your meds as prescribed, you will be fine, maybe, we will get to be cured one of these days, but for now, live everyday as it was the last day of your life, enjoy life and forget about hiv studies…I have done it for 27 years, you can do it too…hugs


Ps. Leatherman forgot to mention about rutonavir liquid, tasted it horribly
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 10, 2021, 11:35:11 pm
Hello guys... Good morning...
How are you?

Thanks for your answers and support.
I have my kidney, every 5-10-20 days to remind me that something goes wrong there..maybe some small stone or sand...and all this is more complicated when I think of bad things...

In 2 weeks I have new tests for general health for 4 months of initiation pills...

Question please??
Finally, after 10 months here...my girlfriend who I know for a gear and a half, she finally leaves me because I don't leave my wife and family... I am sad last days...she is sad too. We finish it with good relations and good feeling but very sad after we used to see each other 2-3 days per week. We slept together 4-5 times per month.. but she is most of time alone and that's why decided to leave...back to her country Poland.

Can I ask you something? From your experience.
How much does sadness like this can impact my hiv health ( VL, cd4 , cancers etc..) ?

Thanks my friends and brothers!!
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 11, 2021, 02:48:02 am
Being sad is not going to change your VL. As long as you have been taking your meds you should expect the VL to remain suppressed.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 11, 2021, 03:25:11 am
EBT-101 Crispr Cas9 technology
 ;D
Guys what about this ?

What about it? Maybe one day, it might be something, but I would not hold my breath if I was you.

EBT-101 is from Dr. Khalili - Now in 2016 Dr. Khalili & co used CRISPR/Cas9 to remove HIV fragments from a live rodent. The publication led to a number of claims in the media that HIV would be cured within 3 years and some people I know stopped taking their meds (foolish). 2021 and still no cure or advancement in treatment from this.

A 2nd paper was published afterwards that HIV could become resistant to CRISPR/Cas9.

https://www.poz.com/article/researchers-use-crispr-edit-hiv-dna-live-animal-cells
https://www.poz.com/article/maybe-crispr-gene-editing-easy-way-attack-hiv

We have threads on this if you are interested:

https://forums.poz.com/index.php?topic=63018.msg
https://forums.poz.com/index.php?topic=74860.msg
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 12, 2021, 11:21:48 am
Hello Jim.. how are you? Long time to hear from you!
I read those articles. If I understood correctly there was some suspicions for resistance, but it was written bsome possible way to overcome this obstacle I think...

So Jim. If it was from 2016, did something change by then and so they will start human trials in the end of this year?

Some final question..
Do things run at the same pace like ten years ago ? I mean some hope from AGT , even if it succeeds , they use to tell on the net that gene editing vaccinations may need 15 years of afterwards watching  to get fully approved and shared to public...

So even if AGT succeeds, in 5 years...it will be available in 20 years from now???

......

Did anyone had any problems with mandible? It's many times I hurt my mandible after getting the illness...

Good evening and kisses and hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 12, 2021, 11:43:57 am
Did something change since 2016, well they are now past the petri-dish/mouse stage and ready for phase 1 testing in humans. 

Quote
I mean some hope from AGT , even if it succeeds , they use to tell on the net that gene editing vaccinations may need 15 years of afterwards watching  to get fully approved and shared to public...

Not sure where the 15 years comes from but presume with AGT you mean the AGT Gene editing? We have a thread on that as well - https://forums.poz.com/index.php?topic=73288.msg

How long is a piece of string?

Generally, things take time to develop & test. There are constantly advances in things, I'm sure some things do go quicker than years before but presuming an idea even works in a petri-dish and in animal testing as expected it's still going to take time to get through testing phases to see if it's indeed safe and effective in humans.

Quote
Did anyone had any problems with mandible?

So jaw pain?

Sorry to hear that, don't leave it but check with your dentist & healthcare provider. You are going to have health issues along the way just like everyone else in life regardless of HIV status.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on October 12, 2021, 02:35:27 pm
How long is a piece of string?
oh wow! That makes a perfect metaphor for things like research. I've never heard it before though. It's probably too heady to be some sort of down-home Southern wisdom I might have heard. LOL
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 12, 2021, 03:01:50 pm
oh wow! That makes a perfect metaphor for things like research. I've never heard it before though. It's probably too heady to be some sort of down-home Southern wisdom I might have heard. LOL

 ;D

Just googled to check, would seem to be a British saying. Although, did not know that and i've heard it in Ireland plenty.

(https://i.postimg.cc/jjvmCSrZ/String.png)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Bucklandbury on October 12, 2021, 03:36:21 pm
Just googled to check, would seem to be a British saying. Although, did not know that and i've heard it in Ireland plenty.

I chuckled.

My grandfather used to calls herons and cranes "shite pokes." As did my father. (My paternal grandfather was born in 1897.) Once I learned much later what "shite" meant, the phrase was utterly perfect after seeing those birds poking around in muck. LOL.

Ah, Éire. So many of us across the pond are still so very close to those roots. Of course, it's all just a hop and skip back to the Olduvai Gorge in the whole scheme of things, isn't it?

==

So this is off topic, but that's how my mind works... If you ever get a chance to do your DNA ancestry testing, I would highly recommend it. It's really fascinating to know your father has ancestral roots back in Scandinavia, or that your mother had north African ancestry, or that you and Ben Franklin are related through his mother's lines.

:-)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 18, 2021, 05:31:24 pm
Good night from here to anybody..
Just wanted to share this with you if you don't know already about this...

https://www.poz.com/article/lymphoma-cause-cancer-people-hiv

How can I just take my three pills a day and move on like nothing happens? It's so difficult to waiting for the cancer to come...

Please tell me what to do?
Sleep all time, eat only veggies , boiled chicken and fruits, and exercise in low tempo?

What else ? It's really hard...ouffff

Food night guys..

6 days to have my tests done..
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 18, 2021, 05:41:14 pm
https://www.globenewswire.com/news-release/2021/10/18/2315509/0/en/Enochian-BioSciences-Announces-the-Successful-Completion-of-an-FDA-Pre-IND-for-a-Potential-Cure-for-HIV-The-Second-Pre-IND-in-1-month.html

ALSO news recommendations showed me this article
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 18, 2021, 07:45:47 pm
Quote
https://www.poz.com/article/lymphoma-cause-cancer-people-hiv

How can I just take my three pills a day and move on like nothing happens? It's so difficult to waiting for the cancer to come...

Please tell me what to do?
Sleep all time, eat only veggies , boiled chicken and fruits, and exercise in low tempo?

Okay, a study of 13 people, why do you think this, as mentioned, this rarely occurring issue will apply to you?

Also, how will only eating veggies, fruits and boiled birds help?

Quote
“As a physician, I am reassured that these events are rare,” Mellors stated. “Although we need to be aware that HIV has the potential to cause lymphomas, it’s such a rare occurrence that there is no need for heightened anxiety now. Clinicians should always screen their patents for cancer as part of routine health care, but people with HIV do not need to fear that they will inevitably develop lymphomas.”
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on October 18, 2021, 07:50:02 pm
Good night from here to anybody..
Just wanted to share this with you if you don't know already about this...

https://www.poz.com/article/lymphoma-cause-cancer-people-hiv

How can I just take my three pills a day and move on like nothing happens? It's so difficult to waiting for the cancer to come...

Please tell me what to do?
Sleep all time, eat only veggies , boiled chicken and fruits, and exercise in low tempo?

What else ? It's really hard...ouffff

Food night guys..

6 days to have my tests done..

Hi, sorry to see you are still struggling with your diagnosis. It takes a while to absorb the news, some a short while, some longer.

Don't wait for the cancer to come, or the dementia, or Parkinson disease. Or any number of other conditions that are out there that affect anybody, not just us. Nobody living with HIV wanted to be in this position. Nobody wants any form of cancer or degenerative disease, unfortunately it happens. This is the hand we have all been dealt, we just have to play that hand the best we can.

Live healthy, important thing to do, but more importantly is to just live everyday. The biggest cause of death in the world is being born. But we have to be born to enjoy a life.

Relax and enjoy yours. Believe it or not, there are people out there who are in a worse position than you. People who would swap whatever disease they have for HIV so they could take the pills and live.

Take care, Dave
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 19, 2021, 12:55:22 am
Good morning Jim , Good morning Dave.
Thanks for this , I really needed it...
Yes it's difficult to digest this but more this waiting for something really bad is killing...

Anyways. Guys can I ask you something?
We are more susceptible to cancers and lymphomas despite the use of ART and suppressed virus??

Hematologist two months ago , she told me it was usual for PLHIV to develop lymphomas with older treatments. Now it's rare and they don't see this usually because of highly active ART.

Also Jim. Generally I told this about sleep, nutrition and exercise because... You remember I'm close to 250 cd4.
Last month I was in a position that my son had brought to home kids flu from school, wife caught it , also in same car with colleague at work with covid finally...

But drinking a lot of water, plenty of fruits, veggies , milk fat free and chicken and green leafs... I think helped my body fight and I didn't catch a cold/flu/covid. Is this a sign that immune with highly active ART works well so it can be able to fight infections and growing cancers??

Please who has some medical knowledge to answer this too to me..my grandfather died of cancer at 56 pneumonscancer because was smoking all day from his teenage..
Grandmother 80 from cancer at pancreas , she was really badly eating all life (sweets and fried everything)

Mom's parents.
Grandmother at 80 because of holis removal surgery but she caught bacteria inside hospital and died.
Grandfather 86 cancer in kidney.

Is my gene to have cancer anyways?

I mean they didn't all have cancer and at mid age!
My dad now 61 , my mom 67. They do fine.

If I'm careful I hope to reach just 60 and if I have then cancer maybe they have better treatment and save me to enjoy 1-2 or more grand children..

Is my thought correct? Will they find some lymphomas better treatment and for cancers too soon ?

What about this treatment of 54 yo who stayed off treatment with better suppressing vl OFF TREATMENT for a year from Enochian Biosciences?

Do we have some hope? Or is my desire for hope only? Is objective or subjective hope??

Food morning

Ps. Is my small pains around my good kidney which also threatens me all the time .. hope about this kidney project will become a reality soon.

Due to my low level of English language , I think I cannot some better and more accurate info about when it's about to roll out this GOD machine ...
Can someone If you have the knowledge tell me if this kind of bioartificial transplantable kidney will be able to remove ART effectively from body or it will be for general population only?

"""At best, dialysis replaces a tiny fraction of the function of a healthy kidney. For example, what do you like to eat? Steak? Potato chips? Pizza? Maybe you are a little more health conscious. Fresh tomatoes. Grapes. An orange? A dialysis patient cannot eat any of these these. The dialysis procedure cannot get rid of the wastes until it is time for the dialysis session, and during the time between the meal, the levels of waste products can rise high enough to be dangerous.""""

https://medsites.vumc.org/thekidneyproject/kidney-project
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 19, 2021, 11:53:21 am
Any comment here please? 🙏🙏
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 19, 2021, 11:54:10 am
Also .. about this...

https://www.enochianbio.com/enochian-biosciences-announces-the-successful-completion-of-an-fda-pre-ind-for-a-potential-cure-for-hiv-the-second-pre-ind-in-1-month/

It's not a potential cure.

It's a potential effective long lasting treatment.
Correct?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 19, 2021, 01:27:17 pm
Also .. about this...

https://www.enochianbio.com/enochian-biosciences-announces-the-successful-completion-of-an-fda-pre-ind-for-a-potential-cure-for-hiv-the-second-pre-ind-in-1-month/

It's not a potential cure.

It's a potential effective long lasting treatment.
Correct?

One guy, shady details from an announcement from the companies own site... not even sure where to start but in short, I am doubtful at this stage it will be either a cure or a treatment.

We have seen people stop ART and VL drop and remain UD for months or even longer before rebounding and that's without any novel treatment like this guy had, far more and controlled data is needed to even confirm this might work. 

I would be might be more interested or take more notice once there is a peer-reviewed study published, not a company announcement and at phase 3 trials, with at least a few hundred people but that's presuming they ever even get past a phase 1 and most of these things don't.

Here is the thing, if I spent my time thinking or reading and focusing on these one-hit wonders over the years, as there seems to be one every year or so, I think I would get nowhere in life as they do happen and then they later on fall flat on their faces against control data or when repeating the results in larger and controlled environments. 

I think Dave gave a good answer to your other questions and it's worth repeating.

Hi, sorry to see you are still struggling with your diagnosis. It takes a while to absorb the news, some a short while, some longer.

Don't wait for the cancer to come, or the dementia, or Parkinson disease. Or any number of other conditions that are out there that affect anybody, not just us. Nobody living with HIV wanted to be in this position. Nobody wants any form of cancer or degenerative disease, unfortunately it happens. This is the hand we have all been dealt, we just have to play that hand the best we can.

Live healthy, important thing to do, but more importantly is to just live everyday. The biggest cause of death in the world is being born. But we have to be born to enjoy a life.

Relax and enjoy yours. Believe it or not, there are people out there who are in a worse position than you. People who would swap whatever disease they have for HIV so they could take the pills and live.

Take care, Dave



Quote
We are more susceptible to cancers and lymphomas despite the use of ART and suppressed virus??

As a group, there are medical issues that happen to us in somewhat greater numbers, although most of them reduce with ART and overall as a group it brings our lifespan to near normal. 

The other issue is "group" data. Most of these studies are lacking or include everything, a real-world example, I am an ex-smoker, alcoholic and generally don't exercise, so I have high blood pressure, had a touch of cancer and a few other health issues.

Are my issues HIV related, no, yet will some if not most studies record my data into our "group" data, yeah. Yet it simply doesn't apply to you, unless you are also a 40-year-old, with drinking problems going back nearly 20 years, high blood pressure and did not take ART for a decade + for various stupid reasons.

Finally.

There is no point in focusing on the factors we can't control. I have a feeling reading your thread a lot of the things you seem stressed about or at least raise as a concern are mostly hypothetical worries, i.e “What ifs, that have not happened, don't apply to you or things you mostly you can't change"

Good news, there are things you can control, factors like quitting smoking, reducing excessive drinking, better-balanced diets, quitting IV drug usage and more exercise. Next, is to attend your check-ups so they can detect and treat issues early, something our negative peers don't benefit from.

The sad news is you will die of something, someday and yes, this could be cancer or simply a fall down the stairs. 

Anyhow, links and references are already provided within this thread so not going to repeat them.

I do understand that you are having a hard time and I wish you well. I also know that having this diagnosis during a pandemic is a double hit and also means attending face to face support such as peer support groups is not possible in Greece but have you discussed one to one therapy/counselling options with your doctor to help you prehaps digest the diagnosis?

Best, Jim

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 19, 2021, 02:03:01 pm
Sorry if I sound harsh, it's not intended.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 19, 2021, 06:06:27 pm
No friend , you were not harsh. You were direct and straight. And I'm thankful and grateful to you for this.

This is true.

But to make a long story short , my concern is exactly this of Dave.... ""Nobody living with HIV wanted to be in this position. Nobody wants any form of cancer or degenerative disease, unfortunately it happens. This is the hand we have all been dealt, we just have to play that hand the best we can.""

I'm watching in this... What is the best we can do as being a member of this group to lower chances to die from hiv related illnesses..

Because I don't know if I'm thinking correct or not, even if suppressed VL , However there is the reservoir that can increase the odds of having hiv related cancers like lymphomas??

I mean , ART and suppressed VL does or doesn't mean equal chances like negative peers of same lifestyle to have hiv related issues??

And one more question similar to this if not the same... Even if they find treatment to make VL undetectable for us....even though not sterilising, but undetectable, we still have hiv related chances of serious illnesses? I.e we need only sterilising cure to be negative again or a functional cure will protect us as well from immune ageing???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 19, 2021, 06:08:04 pm
Jim... Also my gf left Greece unfortunately last week , and maybe she will have job in Dublin soon .. she has cousins there ..I miss her but maybe I will live with less stress and demands....

Hope to see you someday there for a beer...
Have a nice night bros...
Bye
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 20, 2021, 07:36:03 am
Quote
What is the best we can do as being a member of this group to lower chances to die from hiv related illnesses..

Well primarily, take your meds, suppress the virus.

Suppressing the VL and the proven better health outcomes for PLHIV, (reduction of issues and early death), is part of the reason after the START study in the mid-2000's healthcare guidelines and recommendations changed from waiting with treatment to starting treatment as soon as possible. It's currently the gold standard.

Hence in the sticky thread, I included a lot of information on this and also on managing controllable factors.

https://forums.poz.com/index.php?topic=2276.0

Quote
even though not sterilising, but undetectable, we still have hiv related chances of serious illnesses?

As a group there remain certain increased risks, although many are negligible increases and we have regular reviews of our health to detect issues early for best outcomes.

To add, as said earlier what are your other factors and co-mobilities? If you are a 20 a day smoker and drink like a fish, the odds are you will have problems or problems sooner than someone who doesn't.

So again, it depends and you can focus on the controllable things in your life if you wish. Just don't get stuck on things that are uncontrollable and/or rather irrelevant as it's pointless.

Quote
I.e we need only sterilising cure to be negative again or a functional cure will protect us as well from immune ageing???

Well, we can debate the definition of a functional cure, I already have one from my own perspective, that is; A pill a day keeps AIDS away.

Anyhow, if you are thinking something like no longer having to take meds with a fully suppressed VL, I expect it's going to be a mixed result. End of the day nobody knows, if and when we have this type of functional cure we can find out, I suspect it will be like with current treatment depending on what damage has already been done.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 20, 2021, 07:38:53 am
Quote
I also know that having this diagnosis during a pandemic is a double hit and also means attending face to face support such as peer support groups is not possible in Greece but have you discussed one to one therapy/counselling options with your doctor to help you prehaps digest the diagnosis?

Not sure if you got back on this point, but if you have not considered it, I would recommend it.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 20, 2021, 11:28:45 am

As a group there remain certain increased risks, although many are negligible increases and we have regular reviews of our health to detect issues early for best outcomes.
Certain increased risks?? Like for what?

A pill a day keeps AIDS away.
I hope my 3 pills a day will keep aids away.

Quote
Anyhow, if you are thinking something like no longer having to take meds with a fully suppressed VL, I expect it's going to be a mixed result.
What exactly do you mean by "mixed results"

Quote
I suspect it will be like with current treatment depending on what damage has already been done.
Meaning? Can you please provide me with a bit more detailed answer of your thought?

Thanks 👍
🙏
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 20, 2021, 12:07:47 pm
Quote
Certain increased risks?? Like for what?

Well plenty examples given in the sticky thread, but another example and it also talks correctly about lifestyle choices being a factor.

https://www.contagionlive.com/view/people-living-with-hiv-at-higher-risk-of-other-diseases

Quote
What exactly do you mean by "mixed results"
Meaning? Can you please provide me with a bit more detailed answer of your thought?

Sure currently some (too many) people still start treatment late, some people start too late  :'( and others only start after problems have already occurred.

I suspect this will not change and that their outcomes statistically will remain somewhat behind those that start treatment early.

However, I also clarified my thoughts on a functional cure and the outcomes, this I will repeat:

"End of the day nobody knows, if and when we have this type of functional cure we can find out, I suspect it will be like with current treatment depending on what damage has already been done"

You should really read the sticky thread. No point wondering how well a function cure will impact long term health though until we have it and that might be never or next year, who knows.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 21, 2021, 12:50:04 pm
Hellooo can I ask something again?
Last days again I have discomfort to my good performing kidney.. so I was searching and I read this... After I have solution for my kidney problem , then I have to be careful of managing th chronic inflammation only...

https://pharm.ucsf.edu/kidney/device/faq
Please see question 7.

Asks about if some polycystic patients will be candidates for the new bioartificial implantable kidney...

So my wondering nature challenges me to ask..
If this becomes a reality soon, will HIV patients be eligible candidates to take and implant one to themselves??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Matths on October 21, 2021, 05:10:28 pm
What happened to you talking to a psychotherapist?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 22, 2021, 04:16:38 am
What happened to you talking to a psychotherapist?
Good morning at first ..
Why do you ask me such question here?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Matths on October 22, 2021, 06:45:35 am
Good morning. I was asking this question because you may recall that we talked about the obvious huge stress that emerged when you started your conversations here in this forum. You had brought up and keep bringing up many reasons why your future could be early “terminated” by numerous medical problems that could arise because of the HIV diagnosis. I believe to remember that you had, not surprisingly because it happens to most, if not all of us in the situation of being diagnosed with HIV, that you experienced anxiety and multiple fears and distress. And at that time several people here, including myself, had suggested that you may benefit from seeking professional psychological help to mitigate your anxiety.

Since then you have made many contributions to this forum all of which have medical problems as topic. The for me noticeable omission was any mention of psychological support that you may or may not have at this time of your life. That’s why I was asking and was curious to hear if you felt it is helpful (in case you have psychological support). Best Matt
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 22, 2021, 08:51:05 am
Hellooo I'm here for giving and taking support... At this early stage after my diagnosis I need more talk and confirmation from all you and medical maybe persons here...
That we will succeed to have some good quality of life until 60-70.
Now I have these kidney pains hoping to soon have this artificial kidney.

But nobody knows or answers me this...
We , plhiv , will we be candidates for taking one when it comes?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on October 22, 2021, 09:50:16 am
@Matths: I agree, I made the same suggestion quite a while ago.

@Gpapadop91 : I have been on antivirals for like forever....and I am doing just fine.

"Enjoy life today, because yesterday is gone and tomorrow is never promised"
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on October 22, 2021, 01:00:27 pm
Hello Gpapadop91,
No one can correctly answer to you regarding ur kidney pain. Only a dr can answer what may cause these pains only after they check u.
Here u get support but no one here can give your your proper “medical report”.

Don’t get us wrong that we don’t support but there are limit what we can advise. Example: your actual health conditions. That part has to come from your own Dr.

Visit your Dr for ur kidney pains & share with us what ur Dr think it is.
Tks
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 22, 2021, 01:11:24 pm
Look I think at the start of this thread you mentioned pre-existing kidney issues and pains, we did mention you need to talk to your healthcare provider about this discomfort.

As for the device, I don't see why you need it and by the time you might, it could be obsolete already, however, the doctors currently providing you with care for your renal issues might know the answer to your question. I know in the thread we already covered that transplants are also possible nowadays between people living with HIV.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: CircularNatural on October 23, 2021, 01:37:45 am
Good morning there.

Even with a better (seem to..) immune now, I have this oral thrush for a week already today... Should I worry for some precancerous condition or is it something that will be resolve itself???

It's only 1-2 sq cms between cheek and gums ..
Should I go to dentist, stomatologist?
Or to my hiv clinic?

Maybe it's from ART?

Here in Argentina, oral thrush (candidiasis) is generally treated with a Nystatin 100.000 IU solution that you gave to keep it in your mouth and make gargles with it for about 5 minutes and then spit it. This is meant to be done every 6 hours for at least 5-7 days.
Did your MD give you treatment for it?https://www.webmd.com/drugs/2/drug-8893-8206/nystatin-oral/nystatin-suspension-oral/details
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: CircularNatural on October 23, 2021, 02:19:06 am
Hellooo I'm here for giving and taking support... At this early stage after my diagnosis I need more talk and confirmation from all you and medical maybe persons here...
That we will succeed to have some good quality of life until 60-70.
Now I have these kidney pains hoping to soon have this artificial kidney.

But nobody knows or answers me this...
We , plhiv , will we be candidates for taking one when it comes?

You need to see an urologist for your pain. They will probably go for an ecographic scan and see if you have any calculi or "sand". You can get treatment for this afterwards such as ultrasound to break the calculi.
You need to organise yourself first, though.
Continuing with HAART and ID doctor's advises is top priority.
But you also need to get help with your health and generalized anxiety issues. We all understand these are hard times for you, you are also facing some personal / relationship issues as well, so going for psychotherapy and/or psychiatric appointments would really help you out. We really mean this well, please take it into account.
Take care
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 24, 2021, 05:13:56 pm
Hi Circular..
I'm on ART exactly 4,5 months.
Tomorrow, in 8 hrs,  is my tests for after a three month period.
And then I will have again in 6 months from now.

Need cure... I'm too stressed. I don't wanna this fucking virus inside me.. such a science and nothing?
I'm fine but I want to delete this from ourselves.

Guys... Good night to all.
Hugs and sweet dreams
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 25, 2021, 05:13:03 am
Ηi.. they just took me blood for tests...

Can I ask you something?
You all here are my hope.
My doctor is good
But today along with my doctor there were students doctors and after I finished the other immunologist doctor who teaches them...after I was ready to leave something told to students doctors, showed something on my paper and then they looked at me.. don't kid with me...but I know to translate behaviours..it's my job for 16 years. She told them something like looking at me like soon I'm going to die soon, like poor boy, like something strange... I understood and I asked them IS IT SOMETHING I SHOULD WORRY ABOUT??
She then told me , No I just show the initial Viral load..

Anyways. My question to all. You here..is...
I am crazy or them??? Why? Because if it's something bad they should tell me to know...

Anyways. They saw example previous week with someone 9 cd4.  They talked like miracle that he lives yet. Still.

So if really they looked at me like poor because I had so high viral load 48 millions , isn't logical that I'm stressed s bit? Should I forget them and think this what you all told me here?
I mean that if I am undetectable so early from 48 millions , everything will be fine?
With these meds I really feel safe and better than the moment I first wrote here 4 months ago.

Have a good day.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 25, 2021, 06:06:29 am
Quote
They saw example previous week with someone 9 cd4.  They talked like miracle that he lives yet. Still

Why would it be a miracle?? Happens all the time, I'll post some numbers for the EU & Greece later today.

Quote
IS IT SOMETHING I SHOULD WORRY ABOUT??
She then told me , No

You already have the answer.

No point stressing about how students still wet behind the ears react to pretty standard stuff.




Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 25, 2021, 06:08:12 am
Did you talk to your doctor about these ongoing fears and stress?? Did you talk about getting support in that area of your health??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 25, 2021, 07:38:58 am
Getting wet... Hahaha

Just to tell you something..
Because my doctor visits the yearly conferences about HIV.

It's usual last years that patients (he told in absence of ART) decrease faster their cd4 count than what it was a decade ago...

It's something he pointed out , explanation still doesn't exist.

About my health issue meaning the mental...
I'm living all my life with almost one kidney.

I did stupid things in past with proteins , creatine's in bodybuilding.

Now I'm taking ART. One of the most long run side effects is kidney disease.

Shouldn't I worry?

However he told me he foundme now a bit better than before.

And should I tell you all something here?

It's pity because I was doing well in my life. Success was close .. I could see some siblings even envy my family and my progress .. it's pity to think that with my illness I will make them happy.

Yes I shouldn't care. But..
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 25, 2021, 12:25:49 pm
All had low-level viral loads below 80 copies/ml and none met the criteria for resistance testing. Five of the seven people with virologic failure had a high viral load (above 100,000 copies/ml) at baseline. Only one additional participant experienced virologic failure between weeks 48 and 96.

So me having 48 millions...at baseline...
Shouldn't I worry more than normal that I will not achieve a viral suppress on the long run , that I will have failure if they find a functional cure , that I will have some cancer soon????

https://www.aidsmap.com/news/oct-2020/islatravir-plus-doravirine-remains-effective-96-weeks
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 25, 2021, 12:34:22 pm
Hiya,

Quote
Shouldn't I worry more than normal that I will not achieve a viral suppress on the long run , that I will have failure if they find a functional cure , that I will have some cancer soon?

Short answer, no and I don't see the relevance of the doravirine link, it's not meds that you are taking.

Anyhow, this is something we also discussed on the first page of this thread.

You had a viral load, it's not special, you started treatment and the viral load is now suppressed. Keep taking the meds, keep going for check-ups to monitor.

Quote
that I will have failure if they find a functional cure

I don't see why, but let them first find a functional cure and after that, we will see. The type of functional cure you have in mind might never happen.

Jim
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 25, 2021, 01:25:00 pm
Ιt will happen... This from Einstein institute or the Crisprs ..
Meaning a functional cure Jim to avoid taking daily ART to save money kidney on the long run.

Even this with lenacapavir injected twice a year it will be fine.

But let me first show you why I'm worrying. Of course this article doesn't refer to my meds.
But many articles about studies refer to baseline VL.
So with me , that I had maybe from the highest vls ever seen, shouldn't I worry that everything will be a disaster?

Today famous politician woman died from cancer at 55 years.
I want to be protected from cancer...

I'm scared after today's talks with each other between doctors.

Guys...what is my baseline? Because almost everyone in acute phase had thousands at least viral load if not a handful millions. Was mine really 48 millions? So how it could be suppressed within a month of art initiation??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 25, 2021, 01:34:21 pm
Quote
I want to be protected from cancer...

I think most people would like that regardless of HIV status. However, no such protection exists to my knowledge.

You can try to make better lifestyle choices ect, but that's about it.

Quote
Ιt will happen...

Maybe, maybe not. We will see but until it's a reality no point in betting on it or worrying about it.

Quote
So how it could be suppressed within a month of art initiation??

With ease, many of us started with counts in the multiple millions as we waited for our CD4's to deplete or our health to decline to the point we would (finally) start treatment.

It wasn't until the mid-2000's that they figured treating at diagnosis regardless of the numbers was best and it took a lot longer for nations to adjust treatment guidelines.

Quote
So with me , that I had maybe from the highest vls ever seen, shouldn't I worry that everything will be a disaster?

You don't have the highest ever seen, mentioned this on the 2nd page of this thread and no your baseline does not mean everything will be a disaster. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680573/

Quote
I'm scared after today's talks with each other between doctors.

Do you mean the students talking to each other and the doctor who explained to you it was nothing to worry about? It's nothing to worry about.


Quote
Today famous politician woman died from cancer at 55 years.

Yeah, that's sad, nothing to do with you.

On the 14th of October, my ex passed away aged 37 years old, the news hit me like a brick, I only spoke to them the night before it happened.

We will all die someday of something, just because someone died at 37 or 55 does not mean you will or I will, that said I could fall down the stairs tomorrow and you could have a heart attack from the stess/anxiety that you don't have under control. 

Quote
Did you talk to your doctor about these ongoing fears and stress?? Did you talk about getting support in that area of your health??

?

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on October 25, 2021, 03:51:55 pm
@Jim:
"On the 14th of October, my ex passed away aged 37 years old, the news hit me like a brick, I only spoke to them the night before it happened."

WHAT ?????
My condolences
And your kids are with you now ?

Ik schrik hiervan, en je hebt er nergens over gerept
Sterkte

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 25, 2021, 03:58:35 pm
@Jim:
"On the 14th of October, my ex passed away aged 37 years old, the news hit me like a brick, I only spoke to them the night before it happened."

WHAT ?????
My condolences
And your kids are with you now ?

Ik schrik hiervan, en je hebt er nergens over gerept
Sterkte

Thanks and I also apologize, I should have mentioned in my comment that it's not the ex I have the kids with, but the ex before her.

Funny enough the three of us were friends for many years and remained friends. So were all hurting at the moment.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on October 25, 2021, 04:08:07 pm
Oke, relieved that she was not the mother of your kids. Nevertheless a big loss.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 12:56:20 am
My heart full condolences to you Jim .. wish you have a long life to remember her ..🙏🙏🙏🙏
Wishes for a good day...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 03:16:23 am
Jim...as for the article that you sent me with the link above about Viral Load  ...
It's written inside..

Viral loads of over 100 000 copies/mL at the start of ART are linked with a greater likelihood of disease progression.

So , I am 480 fold higher at the stray of ART .. so???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 03:32:39 am
Quote
Viral loads of over 100 000 copies/mL at the start of ART are linked with a greater likelihood of disease progression.

So , I am 480 fold higher at the stray of ART .. so???


No, you are focusing out of context. 

That comment relates to a 2002 publication, a lot has changed since this although it supports the treat sooner changes that happened after newer studies in the mid-2000s found that to be the better outcome instead of waiting as they did in the years before and below I copied out the section that the comment is in. 

https://pubmed.ncbi.nlm.nih.gov/12126821/

Quote
Baseline HIV-1 viral load was associated with a higher probability of progression only if 100,000 copies/microL or above. Other independent predictors of poorer outcome were advanced age, infection through injection-drug use, and a previous diagnosis of AIDS. The probability of progression to AIDS or death at 3 years ranged from 3.4% (2.8-4.1) in patients in the lowest-risk stratum for each prognostic variable, to 50% (43-58) in patients in the highest-risk strata.

Interpretation: The CD4 cell count at initiation was the dominant prognostic factor in patients starting HAART. Our findings have important implications for clinical management and should be taken into account in future treatment guidelines.

You are relatively young, don't have an AIDS-defining illness, you are not using injection drugs, you are taking modern ART with a fully suppressed VL with an increasing CD4 count now above 200 copies.

Now, nobody can predict the future, but all in all, things look good from that perspective for you.  See the sticky thread with the relevant links.

Take your meds, and if you want to live healthier you could cut out any bad habits, eat well, exercise and look after your mental well being.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 03:46:15 am
Thanks Jimm..

But this..???

"""Baseline HIV-1 viral load was associated with a higher probability of progression only if 100,000 copies/microL or above'""

So? Does it mean if you leave it and not start ART?
Or Regardless the use of ART it will progress anyways because it was 480 * this number!!!!????

Again stressed.
I had started taking it easy last period...

What the f@k?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 04:14:21 am
But nothing, you need to stop this.

You already know that more modern studies show near-normal life expectancies, that lifestyle choices and co-mobilities are a factor and what you can do to lead a healthier life if you so wish.

Yet you are focusing on a single line of text out of context, from a review in 2002 over past studies so at the time data from the mid 90's when treatment and treatment guidelines had only just started.

The data is over 25 years old and even at the time, the context was that with treatment, lifestyle choices, AIDS-defining illnesses when starting treatment and other co-mobilities were also a factor in the survival rate. These things are still factors but we can treat health issues better and screen for them as well, also treatment for HIV itself has vastly changed.

Sadly, there are always going to be people who start treatment too late and there will always be a % who die young with HIV. 

There is no logical reason to believe you are one of those and we have discussed this as much as I can.

Many forum members have told you their stories to help you digest your situation and I have provided you with more up-to-date resources as reassurance. You need to talk to your healthcare provider about these ongoing or repeating fears and get professional mental & emotional support to help you cope.



Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 04:15:59 am
Article from WebMD.com

What the Results Mean
A high viral load is generally considered about 100,000 copies, but you could have 1 million or more. The virus is at work making copies of itself, and the disease may progress quickly.

My clear answer that I'm so desperately want is this...

The above statement is true regardless the successful ART?
Does it mean it will progress sooner or for sure to AIDS and that although art is successful now , sometime my hiv type/system combination will make my disease progress sooner and overtake the benefits of my pills?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 04:25:24 am
Jim I am really grateful to all you. Today my wife told me she admires me how easily I have taken this. And that she would have suicide if she was in my position.

But I have not clear information to do my program and choices. Believe me I had good life. Fought hard but I mean I enjoyed my life well and still doing...
I have not problem to die young. I don't want to die from cancer melting on a bed and lose my self esteem and respect.

Also if I know that my disease will progress soon , I will make different choices. I will spend all my time with family.
But if I know it's nea data and new studies show different tngs , I'm continuing to create for my family , work, have dreams etc...

So it's important to know...

So I'm confused. That's why I'm asking.
All this is old and outdated info??

But someone to know if baseline HIV is more strong even than modern effective art ???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 04:28:32 am
You have really clear information, access to first-line treatment and healthcare.

You are just focusing on outdated stuff or out of context text, stressing about students who know nothing, and sadly the few % of people that even with access to treatment indeed don't live that long but again you are doing this out of context and feeding your fears.

Stop reading up on stuff because you are not gaining any wisdom or insights from it, instead see your healthcare team and consider talking to a qualified therapist about these fears.

Quote
The above statement is true regardless the successful ART?

No, the short answer is that successful HIV treatment suppresses the viral load and halts its progression, and the immune system starts to heal.

The slightly longer answer is HIV treatment does not address all aspects, this is true. An example, ongoing inflammation that may result in some generally manageable conditions coming up earlier in PLHIV lives than seen in their negative peers. 

https://forums.poz.com/index.php?topic=2276.0

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 04:38:50 am
Quote
I don't want to die from cancer melting on a bed

Nobody does, but we all have to die from something at some time. In the meantime, all we can do is make the best lifestyle choices we can where possible to reduce our risks.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 04:44:46 am
Ok.
But why do you think a therapist can help me?
Only a specialist in HIV can help me.
And I don't know if you are specialistbin hiv but you indeed helped me a lot.

A question please. Why some people even with access to art die soon? What are the explanations about this?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 05:00:07 am
Why some people even with access to art die soon? What are the explanations about this?

You know the answer, I've posted it half a dozen times in this thread.

Late diagnosis when damage is already done, AIDS-defining illnesses, co-mobilities, drugs, drink, lifestyle issues etc, etc. 
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 05:02:24 am
Quote
But why do you think a therapist can help me?
Only a specialist in HIV can help me.

Why do you think only an HIV specialist can help you? They are done, you are on treatment, VL is suppressed, they will only monitor your checkups, and they are not going to help you with the mental aspect of your HIV diagnosis and learning to cope/live with this.

P.S I am not the only forum member to have suggested this. We're suggesting this because we care and mental health and well-being is a huge aspect of coping with a diagnosis and living with HIV.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 05:10:52 am
I only want them to help me with true prognosis based on new studies , the new art meds I take , my data ...

Not with mental health...

Jim... I think I found what I needed...

In the same article later on....

Look..
Talking about cd4 counts. All is said below...
IF ART IS NOT INITIATED
Quote
Your test results help your doctor know how much damage has been done to your immune system and what's likely to happen next if antiretroviral treatment  (ART) is not initiated.

_____

Then .. here....
Quote
A viral load that can't be detected -- less than 20 copies -- is always the goal of HIV treatment. This doesn't mean you're cured. Unfortunately, the virus is still able to survive in various cells in the body.  But maintaining an undetectable viral load is compatible with a normal, or near-normal life span.  Continuing to take your medicine as prescribed to keep the virus undetectable is very important..
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 05:14:24 am
Finally my tests on this hospital have reference limit the 20 not the 40,50 or 100.

Makes sense I had less than 20??


So my last to worry about is my cd4.
Because I read on multiple articles , and I think you told me too... The most important is the cd4 ability to rise again on suppressive virus....
Correct?

If I still have 200-300 ... I should stop hoping for long lifespan...
Let's see...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 05:17:47 am
Glad you have the answer, we provided all of this already within the first few pages of this thread.

Anyhow, I still would encourage you to speak to a psychotherapist. You could find it very helpful and gain some perspective & coping skills.

Quote
The most important is the cd4 ability to rise again on suppressive virus....

Not really, again context. Anyhow, in short, CD4 count is not a measurement of health and as your count is above 200 (14%) and your VL is suppressed, it's rather irrelevant going forward.

This was also discussed in the first few pages of this thread so ill just reference that.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 05:21:32 am
Finally my tests on this hospital have reference limit the 20 not the 40,50 or 100.

Makes sense I had less than 20??

Yup, most modern labs will have a threshold of 50 or 20 nowadays.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 26, 2021, 02:16:55 pm
Again here..
Good evening how are all you?

I had before contracting the virus some two small lymphs touchable in my left side of neck...and one small but bit bigger than each on the left...

Now they are a 10% bigger , all three, touchable , not seen and not as big as they were during my acute phase in May.

Should I think it will become a lymphoma sometime ?
Because even before , it was always there...last ten or 12 years..

Forgot to inform you that during seroconversion I had some pain when moving my eyes totally left or right to the end and not see well from there .. maybe it was associated with the latent CMV that I had before contracting this.

Guys  ,see you and good night.
🙏🙏🙏🙏 God bless you all.

I have to tell you that without you all here I wouldn't be so well... Maybe you hear me not well but it's only six months having this with scary numbers ... So I need time.
But you cannot imagine how much you offered to me.

Before I take my 1st months results , I cannot explain how I kept myself from suicide , I was totally panicked and couldn't believe that my viral load could ever fall undetectable.

Jim , Matt, Mike , Leatherman grasshopper all of you sorry if I forgot someone , you saved me.

After experience, my lesson is this now..my knowledge I mean.
I lost my life wondering and worrying so much the first month, finally.

Guys , I thought a question now..
All these stories from your that give us a hope...
Is the exception of the rule not the rule, correct?
Or is it the rule with the modern meds.?

Bye guys...
Good night
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Grasshopper on October 26, 2021, 02:28:30 pm
Again here..

...... some two small lymphs touchable in my left side of neck...and one small but bit bigger than each on the left...

Now they are a 10% bigger 



Small and yet you are able to estimate a growth of 10% ?????   :-X
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 02:33:29 pm
Quote
I had before contracting the virus some two small lymphs touchable in my left side of neck...and one small but bit bigger than each on the left...

Now they are a 10% bigger , all three, touchable , not seen and not as big as they were during my acute phase in May.

Go see your healthcare provider. In the last few months you have seen plenty of doctors, get one of them to have a look. Could be nothing, like fat lumps or normal nodes that you have been annoying, but best have a doc check it.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 26, 2021, 02:36:41 pm
Quote
All these stories from your that give us a hope...
Is the exception of the rule not the rule, correct?
Or is it the rule with the modern meds.?

It's not just individual stories, it's data, included in all the studies & publications in the sticky thread to back them up.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 28, 2021, 05:12:56 pm
Helloo there...good evening...

https://www.pinknews.co.uk/2021/10/28/hiv-cure-excision-biotherapeutics/

It's talking about starting the trial of Crispr technology..

I read sth like this in several forums however didn't see yet an article Talking about the day of starting the trial..

Does anyone know something??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on October 28, 2021, 05:34:22 pm
There are threads on EBT-101 and CRISPR.

Nothing new to report though
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on October 29, 2021, 12:24:45 am
Helloo there...good evening...

https://www.pinknews.co.uk/2021/10/28/hiv-cure-excision-biotherapeutics/

It's talking about starting the trial of Crispr technology..

I read sth like this in several forums however didn't see yet an article Talking about the day of starting the trial..

Does anyone know something??


          ojo.            Hello there!…I wonder how much time you are wasting in searching for something that eventuality, if it were to happen, finding the cure, your doctor will be the first one in telling you, so, please stay away from the web and continue with your life before your dx…we are here to support you but, we also are here to let you know that what you have been doing it’s causing you stress which it’s not good for you, and, to tell you the truth, asking always the same, may make some of our member bored and they might ignore you. Don’t get me wrong, I’m trying to help you, I used to do the same and I couldn’t recuperate the time I wasted searching for information, but, when I was wasting time searching for information it was to know if I had a chance to keep living, when I got my dx, we made plans for our funerals, which isn’t your case, you can keep making plans for the future…take advantage of this second chance to LIVE…good luck
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on October 29, 2021, 10:59:04 am
I don't get you wrong... instead thanks because I understand why and how you tell me this...
Nice to hear..
Maybe it's a try to have more contact with you , my brothers, because I feel loneliness in all this.... Only my wife a bit understands me.... But no-one can like you...

Thanks and please don't get me wrong too...
Kisses good night
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 09, 2021, 06:49:56 pm
Hello there... How are you???

Is everything fine?? Tomorrow I'm going to take my results...

I will get you posted .. 💪💪

I have a question seeking an answer from people who take or tried isentress (raltegravir).
Today my best friends grandmother found to have elevated liver enzymes transaminases. And they think about cancer.
They will see...and they think it maybe from 10-15 years of antibiotics... Because she was taking antibiotics for some reason I didn't understand...
Also
What I know for raltegravir is that it's metabolised by liver , not kidneys as Descovys tenofovir and emtricitabine.

So how can I be sure or just hopeful that my liver will live for 20 or 30 years??

So my general question is (because I know about your answers that we cannot know future and you have right) if there is already known after 15 years of isentress existence if it is generally safe or safer compared to antibiotics for example???

Thank you , good night and sweet dreams guys..
CU
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 09, 2021, 07:10:13 pm
There are threads on EBT-101 and CRISPR.

Nothing new to report though

Hi Jim...hope you are doing well.. 🙏
I could not read all... But understood something like as backfalls from this technology , like , although viral genome was cut to many pieces it could reform and reactivate...

Also..
Somewhere within the article , I think where is the start of the analysis (abstract) it says ALTHOUGH HAART CAN ELIMINATE REPLICATION AND CONTROL HIV HOWEVER HIV CAN REACTIVATE SOME TIME.. 
My question here is ; even under HAART?

https://journals.asm.org/doi/full/10.1128/JVI.01358-21
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on November 09, 2021, 09:08:14 pm
Somewhere within the article , I think where is the start of the analysis (abstract) it says ALTHOUGH HAART CAN ELIMINATE REPLICATION AND CONTROL HIV HOWEVER HIV CAN REACTIVATE SOME TIME.. 
My question here is ; even under HAART?
yes. ARVs are not able to totally destroy all HIV (which would be a medical cure). this remaining virus goes latent/dormant and rests within "reservoirs". Occasionally some of this HIV may wake up and begin replicating again. Because the med level stays high enough when a patient stays on daily meds, the virus quickly gets blocked again and so no harm happens to the patient. Sometimes when you have blood work done exactly as this dormant virus reactivates, your results could show a some blip in viral load.

ARVs are not a cure; but they are medication that control HIV almost completely if a patient remains adherent to this daily medication.


The gist of it all is take you daily medications, quit worrying, and go on with your life  ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 03:11:22 am
Leatherman .. good morning.. how are you? Nice pleasure to see you here again. You are my motivator!!!
Thanks for your reply...

Could you please tell me also if you know about these new meds what I take?  Are toxic enough to our liver?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 03:28:31 am
Could you please tell me also if you know about these new meds what I take?  Are toxic enough to our liver?

New meds? Do you mean the raltegravir?

Raltegravir is not toxic as such and you are being monitored to make sure things are okay. If you remain concerned you should also raise these concerns with your healthcare provider.

https://www.ncbi.nlm.nih.gov/books/NBK548313/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108567/

How did your appointment go today with your healthcare provider and did you talk to them about your concerns and prehaps some mental health support?



Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 04:28:09 am
I just took my results

Diagnosed with 167 cd4 , 2800 wbc
One month art 276 cd4 , 5600 WBC , 18%
4,5 months art 326 , 4050 WBC , 21%
Transaminases , cholesterol , LDL , triglycerides all high but within normal limits
Creatinine 0.9
Urea 33

They told me , the secretary that is important the percentage from 18 to 21%.. I don't know what percentage is this..

Anyways.. my big fear is why cannot I increase my WBC??
In one month I got them to 5600
A month after 3800 and now 4050.
I feel unsafe with this because also my cd4 don't increase enough. And I think they will stop around 400-500

Anyone with medical knowledge can help me with this?

Maybe an untreated eye inflammation in the lip of eye that I have from August doesn't help me to recover a lot??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 04:39:14 am
New meds? Do you mean the raltegravir?

Raltegravir is not toxic as such and you are being monitored to make sure things are okay. If you remain concerned you should also raise these concerns with your healthcare provider.

https://www.ncbi.nlm.nih.gov/books/NBK548313/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108567/

How did your appointment go today with your healthcare provider and did you talk to them about your concerns and prehaps some mental health support?

Τhanks Jim for all this...

So , just from introduction I can see it's a safe drug!

I was on positive voice now. They want me to take part in local study about newly diagnosed people who are straight.. and he told me , because he is the person who supports newly diagnosed people with talking and generally... That me, cause I meet trans women I am bi and not straight. However my profile matches more to a straight man than to a binor gay.
What is the updated new information?
I never was attracted to a man's beauty also even in the idea I'm negative. With transwomen I'm so excited that they are perfectly shaped , much more feminine than almost all women, and know to please you sexually... I find them so sexy that I cannot resist some times ...and that's why I got it... No problem now. Everything is fine..
Just wanted an idea ..
See you guys.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 05:07:39 am
Quote
I feel unsafe with this because also my cd4 don't increase enough. And I think they will stop around 400-500

The viral load is suppressed and they are above 200 and at 21%, so the CD4's are rather irrelevant now. However, I will say in under 6 months, your CD4's have doubled in the count. Anyhow, it's nothing to worry about.

This was also mentioned on the first and second pages of the thread with links.

Your healthcare provider should be explaining this to you as well.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 05:10:16 am
Should I expect them to increase more?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on November 10, 2021, 05:13:16 am
Is you white blood count not on normal range at 4050? My recent report, has a scale of 4000 to 10,000, unless I am mistaken. Mine is 4500 so not much more than yours unless I am reading my report wrong.

As Jim said, your health care provider will monitor you regularly. Anything out of normal I am sure they will intervene.

Deep breaths, relax, happy thoughts.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 05:16:19 am
Should I expect them to increase more?

They might, they might not. With most people, the counts improve in the first year, like your numbers are doing, but with the numbers you have, it's not a concern and it's not a measurement of health either.

It's over 200 or 14% so, try to relax. Again, if you read back this thread page 1 & 2 we discussed this.

As for the WBC, if the healthcare provider is not worried then don't stress about it. Seems like normal or near-normal range to me and within the first few months of starting to treat HIV and an immune system still healing I suppose it's somewhat expected to have slightly lower numbers.

But if you are concerned talk to your healthcare provider.

https://ada.com/white-blood-cell-count/
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 05:33:22 am
I suppose it's somewhat expected to have slightly lower numbers.
Didn't understand this.
You mean you expected a bit Lower
Or
It is a bit lower than what expected??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 05:36:00 am
Should I ask a logical question?
Does lifestyle play a role??

I mean , the first month I was sleeping at 10 every night.
Didn't eat chips, fries , fried foods, not sweets ...
Not working second job not stress...

After I saw good progress within a month on art ,

I started holidays...
Late night sleep.
Second job.
Stress
Chocolates
Ice creams
Fries
Burgers
.

Do you think they play a role??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 06:42:31 am
Didn't understand this.
You mean you expected a bit Lower
Or
It is a bit lower than what expected??

Might help to look at the whole sentence I wrote not just a section.



Quote
As for the WBC, if the healthcare provider is not worried then don't stress about it. Seems like normal or near-normal range to me and within the first few months of starting to treat HIV and an immune system still healing I suppose it's somewhat expected to have slightly lower numbers.

You only just started treating your HIV. Your immune system is still healing for lack of a better phase and some of your numbers were somewhat low, not unexpected and now they are normal or near normal. That's okay.

Quote
Does lifestyle play a role??

Look prolonged stress is bad for people in so many ways.

Eating a burger and fries from time to time is not an issue, neither is eating the odd ice cream, or having a late-night from time to time, or working two jobs. That's called life.

HIV will not care and nothing you eat will permanently change your CD4 counts either, if you are eating just burgers and fries all the time and always skipping on sleep that could be a health issue regardless of your HIV status.

A few of us have already mentioned this, but, if you want to live healthier there are things you can do, it's basic stuff, like don't smoke, cut out excessive drinking, eating a balanced/healthier diet, getting sufficient sleep and exercise and really important is also to look after your mental well-being.

This does not mean you can't have a night out, or never party again or eat some fries from time to time. Of course, you can.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 06:54:55 am
See:

https://forums.poz.com/index.php?topic=2276.0
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 07:06:23 am
BTW.

The CD4 concerns you raised weeks ago on your first page of this thread, WBC by pages 2 & 3 and lifestyle questions on the same pages.

Have you discussed any of these items with your healthcare provider?

Because these concerns at the time, still seem to be a concern now, nothing we have said as a group seems to give you any peace with this and we can only give so much supplementary info besides sharing our personal experiences.

Really you need to talk to a healthcare worker if you keep having these concerns.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 07:10:54 am
Deep breaths, relax, happy thoughts.

Fully agree.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 07:40:44 am
Thank you , I understand your words, still have some logic worries ..

I was more happy when could have 5600 within a month. And a big increase of cd4s with a very careful helathstyle.

But now... cannot having better health results is a reason to make me wonder what makes the difference in my numbers.
So I can be able to know what which is in my control ability I have to control.

Just this.

🙏🙏 thanks all
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 10, 2021, 08:02:55 am
Sure I see your logic, it's the same as this:

I flushed the toilet this morning then it started to rain.
Therefore, my flushing the toilet must have caused it to rain outside.

Thankfully we all know better ;)

On the CD4's, they have changed regardless of your lifestyle. In your case, it's an upward climb after starting to suppress the viral load so your immune system can stop fighting a losing battle and focus on better things.

Similar although not the same can be said for your other lab results, it's going to take time for things to settle and for your system to heal. Keep that in mind, and that even if you measured your labs every day they would go up and down, and that's normal variance.

In a more general sense, helping your immune system and healthier living you can do, the basic stuff as mentioned, but eating some fries and an ice-cream did not change the outcome.  ;) Reducing stress would be good.

Talk to your healthcare provider.

They were not concerned during your visit about your labs for good reason and if you are still bothered ask them to explain why they are not concerned and what you can do to improve/maintain your overall health.

Quote
A few of us have already mentioned this, but, if you want to live healthier there are things you can do, it's basic stuff, like don't smoke, cut out excessive drinking, eating a balanced/healthier diet, getting sufficient sleep and exercise and really important is also to look after your mental well-being.

This does not mean you can't have a night out, or never party again or eat some fries from time to time. Of course, you can.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on November 10, 2021, 08:16:31 am
Are toxic enough to our liver?
ugh. I hate this kind of talk.

Toxic items are poisons.
ARVs are NOT toxic.
No medications are toxic.

Are some meds harder for the kidneys to handle well? yes. but even that is still not "toxic".

never use the word "toxic" again with any medications or treatments.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on November 10, 2021, 08:24:51 am
So I can be able to know what which is in my control ability I have to control.
as far as HIV:
all you can do is take ARVs. period. full stop.

if HIV stays suppressed by daily medications, the viral load will remain undetectable and the rest of your body will do what it was genetically programmed to do based on the genetics of your parents.

Of course, living "healthier" can help you "feel better"; but there is nothing except meds to change your body's handling of HIV. Eating healthier, exercising, no smoking, etc. will help you be healthier to fight of diseases but do nothing to change HIV. These things might give you a small boost in cd4 count but there is nothing that will change your cd4 count except taking HIV meds to keep HIV from destroying your cd4s

I understand you're wondering what to do to be healthier now that you are HIV+, and the answer is very easy and very simple (and it's been said dozens of times in this thread): you only control HIV by taking daily medications. that's it. It's not complicated. It doesn't require not eating certain foods, not drinking alcohol,  stopping smoking, etc. It only requires taking your meds daily. Treating HIV really couldn't be easier, don't try to make it more complex. ;)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Bucklandbury on November 10, 2021, 08:30:32 am
Sure I see your logic, it's the same as this:

I flushed the toilet this morning then it started to rain.
Therefore, my flushing the toilet must have caused it to rain outside.

I love this one. Hahaha. Logic 101.

Post hoc ergo propter hoc.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 10, 2021, 09:09:10 am
ugh. I hate this kind of talk.

Toxic items are poisons.
ARVs are NOT toxic.
No medications are toxic.

Are some meds harder for the kidneys to handle well? yes. but even that is still not "toxic".

never use the word "toxic" again with any medications or treatments.
Υes sir. You have right. I will not use this word.
Thanks 👍 Leatherman
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 15, 2021, 10:53:19 am
Hello there...
Hope everyone is fine... Guys...
I am wondering if this is true or its from old data??
Please 🙏 tell me , do we really have risks for sarkomas, lymphomas and cancers so much more , like 35 fold higher than hiv negative peers, like what I read on this article???

""Epidemiology of KS in Virally Suppressed HIV-Patients
Few observational cohorts have specifically studied the risk of KS in PLHIV with
suppressed viremia. In the French ANRS CO4 FHDH cohort, PLHIV with undetectable
plasma HIV-RNA and restored immunity (i.e., CD4 ≥ 500/mm3
for at least 2 years) still
had a 35-fold higher risk of KS compared to the general population (standardized incidence
ratio (SIR) = 35.4; 95% CI 18.3–61.9) [3]
""

Link
https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.mdpi.com/2072-6694/13/22/5702/pdf&ved=2ahUKEwin2pK725r0AhU8SvEDHSYKDxQQFnoECEIQAQ&usg=AOvVaw2J0MTkOCqLgwHZny3crcR8
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 15, 2021, 11:30:32 am
Kaposi’s Sarcoma in Virally Suppressed People Living with HIV: An Emerging Condition

https://doi.org/10.3390/cancers13225702
https://www.mdpi.com/2072-6694/13/22/5702

Some of the data I would have excluded but overall it's up-to-date that certain cancers like KS are still more prevalent within the HIV community compared to HIV negative population.

Looking at KS, we have known for many years there was a large reduction in cases comparing the pre and post HAART area, however, KS can still develop and those that started with lower CD4 counts seemed to be most at risk.

Nothing to start stressing about, increased prevalence within the community is something already discussed a few times in your thread.

Example:
Mocroft A et al. The changing pattern of Kaposi’s Sarcoma in patients with HIV, 1994-2003, the EuroSIDA study, 2004. 
Quote
”We observed an overall decrease of 39% in the incidence of KS since 1994… among patients receiving HAART there remains an increased risk of KS for homosexual men and for patients with low CD4 counts,” comment the investigators.

They conclude, “we have demonstrated a sizeable decrease in the incidence of KS among European patients with HIV, despite the finding that KS continues to represent the AIDS-defining condition in approximately 6% of all AIDS diagnoses. Most patients who developed KS whilst receiving HAART had low CD4 counts at the start of treatment and developed KS within six months of the initiation of HAART. A greater incidence of KS among homosexual men continues to be observed, as does a significantly reduced incidence of KS among patients with relatively high current CD4 counts.”

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 15, 2021, 12:22:01 pm
with lower CD4 counts seemed to be most at risk
Hi Jim..thanks for sharing.

By this it's also containing me???.

1.
I found out on internet , and even if it's bad for me , I am more calm because I know what happens and explain the two days back topic , about my not good increase in cd4 counts.
I found out after starting HAART , 1st month you gain about 100 cd4 and an estimate about of 11cd4s per month the first year.

2.
So in about a year I will have close to 450. Also below to 500 ...
Does that mean I will lose sooner my ability to fight infections in the future?

3.
.Because I read that people who were diagnosed with cd4<200 are having on average 8 years less lifespan compared to those ones diagnosed with more than 200.

4.
The only difference In my numbers and what I did before, so maybe I can help a bit my immune was the sleep habits.
First month , I was , you remember , OCD.
I WAS SLEEPING AT 22.00 TO 08.00 EVEY DAY.
AFTER MY 1ST MONTH RESULTS AGAIN LIKE ALL MY LIFE I SLEEP AT 2-3AM TO 7-8-9 AM , MEANING 4-7 MAX HRS PER DAY.

I STARTED AGAIN YESTERDAY SLEEP ENOUGH AND FUCK IT EVERYTHING ELSE WHAT STRESSES ME....

I WILL TEST MYSELF IN 3 MONTHS AND SEE IF IT WORKS.
Do I have any chance to help or boost a bit my immune to reach the psychological threshold of 500 around coming summer?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on November 15, 2021, 12:36:39 pm
Why are you stressing over something that you have no control?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 15, 2021, 12:50:37 pm
These questions have been discussed & answered by multiple members in your thread already, particularly the life expectancy thing you seem to be so stuck on.

Nothing has changed since the members answered last time, except you are freaking out again and asking the same questions over and over.  https://forums.poz.com/index.php?topic=75399.0

HIV, take your meds that will suppress the HIV, go for your check-ups and that's it! Nothing more can be done in terms of HIV. Now, if you also want to also live healthier in general and reduce your risks for other conditions then by all means do.

P.S

Quote
I WILL TEST MYSELF IN 3 MONTHS AND SEE IF IT WORKS.

In three months the odds are your counts will be higher, regardless of what you do.
This is just more flushing the toilet, watching it rain and thinking it's somehow connected.   

By all means, though, get some more sleep. Might help calm you down and with your general immune response/well-being.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 15, 2021, 01:34:17 pm
Why are you stressing over something that you have no control?
To know.. knowledge will give me data..
Data will be useful to make me search exactly what people having same situations can do at their best TO REDUCE RISK FURTHER.
Is it so bad?
If I know that although suppressed , we still have 35 fold higher risk , it means we have to try more to rest , search how to reduce risk for specific conditions etc...

Please don't misunderstand me... It's fear, it's feeling pity for all of us, it's fear how hard our death can be... Its all caused by our instinct to survive..

🤗🤗🤗
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 15, 2021, 01:43:22 pm
Thanks Jim.

But as for my cd4 counts! Was someone able with 150 cd4 starting HAART to reach some time more than 500 even after 1-2-3 years???
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 15, 2021, 02:09:45 pm
Thanks Jim.

But as for my cd4 counts! Was someone able with 150 cd4 starting HAART to reach some time more than 500 even after 1-2-3 years???

Yes, plenty of people including some of those answering your questions in this thread. Again remains irrelevant.

Quote
Data will be useful to make me search exactly what people having same situations can do at their best TO REDUCE RISK FURTHER.
Is it so bad?
If I know that although suppressed , we still have 35 fold higher risk , it means we have to try more to rest , search how to reduce risk for specific conditions etc...

No it's not useful as you don't yet seem to have the frame of mind to digest or understand it, as we have seen time and time again. All this stress over a single review paper that ultimately told us nothing new.

Also, you already have the answers to these question on what you can do, we covered cancer and prevention, lifestyle choices and health etc, it's been explained and shared dozens of times by the members.

Not to be funny but are you hoping to find something that doctor's, scientists, healthcare providers and us as a community collectively somehow missed over the past four decades?

Have you discussed these reoccurring fears of illness & health management with your doctor? Because these are all the same concerns you had when first diagnosed.

Do you think we're keeping something you from you??

I understand that you are still trying to cope with the diagnosis but this merry-go-round of focusing on the same topic is not helping you and neither is freaking out whenever you read up on the same again as nothing changed so the answer is the same.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on November 15, 2021, 04:25:21 pm
I found out after starting HAART , 1st month you gain about 100 cd4 and an estimate about of 11cd4s per month the first year.
hahaha
maybe that's some average in some research but that's only an average. cd4s are very fickle. The climb to an improving cd4 count (say going from 5 to 450) is not a straight climb. It's possible for numbers to go up and down with every test. The best way to consider your cd4 count is by the change in 3 tests taken over a period of 6 months or so.

more than 500 even after 1-2-3 years???
hahaha
it took me 27 years of meds to get to 500

it's fear how hard our death can be
know what a hard death is?
Dying from AIDS before there were meds. Or dying from AIDS by not being tested and not getting treatment until  too late when already in the hospital dealing with non-Hodgkin's lymphoma. That's how my previous two long term partners died.

know how to avoid that hard kind of death?
Do like I have done. I've been taking HIV meds for 3 decades ... all without cancer or any of the things you've been worrying about.

I have a few suggestions:
don't read anymore about HIV for 3 months; just take you meds.
don't think or read about cancer anymore for the next 3 years; just take you meds.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on November 15, 2021, 05:08:23 pm
To know.. knowledge will give me data..
Data will be useful to make me search exactly what people having same situations can do at their best TO REDUCE RISK FURTHER.
Is it so bad?

As Leatherman said CD4 climb is not a straight climb. We know because of our CD4 history. I am into my 6 years & still hv not reach 500. (I am not bothered as I am UD).

Here is my prediction.. later when you don’t see ur CD4 going up as much as u think, then you will start to “panic” & google more & post more “data”. What we are concerned is your mind & hope u could “give ur mind a rest”.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on November 15, 2021, 10:59:29 pm



         ojo.             Hi all!

I really think that our OP friends needs to look for some profesional help so he can start coping with the dx, I’m not trying to be mean but, it hurts me to read everything he is posting and I think we are not helping him…just a thought…OP, best of luck to you, look for help and find something and someone to give your life something to do.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 16, 2021, 03:13:11 am
Jim thank you so much 😊 really 😊 I'm sorry that I disturb you all the time..🤗 I am fearing of these things to not happen to me because there is the stigma yet when everyone will learn about my illness...

Leatherman I am grateful bro you for your help.. believe me guys , you believe it or not you do help me all this... Even by talking to me is help.. only with you I feel more safe...
Yesterday I was thinking how more badly I would feel if I didn't have you all from beginning... I was almost ready to suicide or not really but so badly feeling, that after reading your replies , that most studies are 20-30 yearsl old...etc bla bla bla.. that my doctor didn't tell me... I am really feeling well...
Especially after my 1st month test with undetectable in 30 days from 48 millions and a jump from 160 to 280 , I really felt well mentally that I started again bad lifestyle... Sleeping late, eating pizzas , chocolates , ice creams , burgers at least day after day if not every day....
It's logical I think that this doesn't help as much as sleeping at ten and eating veggies and fruits and lean meat protein without fats.

Now my target is to start exercising because I didn't do yet.
I will walk every afternoon ☀️🌷...
And already started again sleeping earlier..not ten but midnight at least.

So guys don't think you don't help me. It's help , but I want you to understand it's early for me and until I feel safe from reaching something about more than 350 cd , I am panicked when I read about 35folds higher risk for KS.

Virgo were you really diagnosed with KS , that's why you suspect hiv? Oh my friend , you have really big balls , I would be more scared of KS than hiv. I would have heart attack.
Does a very low cd4 count as your 4 played a role to have this?

Guys last question.. even with ART , and a cd4 count more than 350 , we still have risks for Lymphomas ??
Because as Leatherman told it's really hard to die from this when they didn't have HAART. But even despite the use of HAART we are still susceptible to lymphomas?

I remember hematologist in July telling me that they don't see yet lymphomas last year's with the new drugs... Is it true from your experience???

Finally.
Leatherman , again.. I am thankful to you.. I will follow your suggestions. I will not read again for 3 months.
But for cancer to not read again for 3 years , I am not sure...
For 3 months I can promise.

Guys WISH YOU GOOD LIFE , GOOD MORNING , GOOD FRIENDS TO LOVE YOU... BECAUSE I LOVE YOU...

THANK YOU 💗 🤗☀️☀️☀️
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on November 16, 2021, 03:26:39 am
Quote
Guys last question.. even with ART , and a cd4 count more than 350 , we still have risks for Lymphomas ??

Quote
But even despite the use of HAART we are still susceptible to lymphomas?

You are doing it again, asking questions asked repeatedly before when you already know the answer.





Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Bucklandbury on November 16, 2021, 07:41:03 am
https://www.amazon.com/Stop-Obsessing-Overcome-Obsessions-Compulsions/dp/0553381172

(https://images-na.ssl-images-amazon.com/images/I/51WCgeRW88L._SX312_BO1,204,203,200_.jpg)

I highly recommend this book, OP.

Good luck!
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 16, 2021, 08:21:22 am
I will really buy it and read it on Kindle..

Thank you 😊 🤗
Maybe it will help me..a bit..
Good afternoon all...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on November 16, 2021, 09:40:40 am
Virgo were you really diagnosed with KS , that's why you suspect hiv? Oh my friend , you have really big balls , I would be more scared of KS than hiv. I would have heart attack.
Does a very low cd4 count as your 4 played a role to have this?

Yes, I have KS. Same time also swollen face. Lymph-notes not filtering well. Try not to think that low CD4 equal getting KS or any other ID since now you have started medication. HIV is no longer able to do damage. If you start thinking “what if” or “when will I get” then it will be stressful now & forever.

Take a day at a toll me & go on with your normal routine. See ur Dr when the dates comes. Many of us do this & the Dr visit to most of us is just to routine. Hope u can stop worrying too much. 
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 16, 2021, 01:28:24 pm
Virgo .. thank you at first place...

Do you mean , you have or you had?
Seems had in 2015.
But after chemo and ART it disappeared.
Correct?

Wish you all the best bro..
Good night guys...
Bye
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on November 16, 2021, 06:06:21 pm
I am not sure if “I have or I had”. The spots is barely noticeable now.
Will the spots appears again? I don’t know
Do I still have the virus that causes KS after cancer treatment? I am not sure.

What I know is that my health is much healthier now with me taking ART & KS will most likely will not appear again. Nowadays, my HIV session with dr is just to extend 6 months of medication. Nothing much is discuss on HIV topic except they just read out my blood test results. More time is being discuss on my cholesterol plan then hiv.  :D

I hope you see what other members is trying to explain to you on why you should not think too much after you start treatment & move on with your daily life. Almost everyone will go through what you are doing now (like goggle or read hiv) but most will not be stress by “what if” or “when will I die” thoughts by going back to normal life routine. 
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 17, 2021, 12:33:37 pm
Thanks Virgo .. wish you all the best... F@@k it this KS.
Good night.
Wishes to all for best ....
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 25, 2021, 05:10:30 am
Good morning guys
I don't know about your countries..
But here VL is given to us after 2wks or a month..

Finally
Again UNDETECTABLE..
THANK TOU GUYS FOR THE SUPPORT.

I REALLY THINK WE HAVE A SECOND CHANCE WITH ALL THIS.

Hope we will have soon better and less harmful for kidneys/liver pills or generally treatment..

Good MORNING 💗🌞🌞
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on November 28, 2021, 06:53:12 am
Good afternoon guys... Have a nice Sunday
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on November 28, 2021, 07:43:09 am
Hello there.
Hope you are enjoying ur weekend. Hope u r taking a break & go about ur daily routine.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on November 28, 2021, 09:09:48 pm




            ojo.         Hello again!…I’m glad you, it seems, are taking back control of your life, you know what I mean, don’t you?…take care and remember that you are still the same person before your dx, just take your med and a good attitude will help you to do back to live a “normal” life…please keep us posted…good luck
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on December 16, 2021, 02:04:34 pm
Hello there.. good evening , wish you all having a very merry Christmas 🎄🎄🎄
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on December 17, 2021, 12:42:31 pm
Merry Christmas to you too. How are you?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on December 31, 2021, 11:15:38 am
Hellloooo guys ... How are you???
I'm here , anyways was about to send wishes later tonight for happy new year, but now a friend from our community, had disappeared, I sent him now and told me he has bad health issues.. Wasn't related to our situation BUT AS I TOOK perfect support from here , I needed to hear info from similar cases to transfer him what I learnt from here....

Especially he has FALL OF END EDGE of his left foot... it's totally paralysed... Fuck

Any idea someone? Is because of disease?
Also I have some acid acute pains sometimes on spinal cord on my back inside the skeleton...

Don't know what is ...

My wishes to all of you....
And he is searching what is and how to treat
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on December 31, 2021, 12:10:07 pm
He now told me ha had magnetic icon and has 3 big bulbs in his spinal cord... Dont know what is...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on December 31, 2021, 01:51:38 pm
Hiya,

Sorry to hear that your psychologist fell and hurt themselves and they are in poor heath. Not sure why you think it's HIV related but regardless it's something they need to sort out with their MD and not reflective of your health.

Perhaps time to find another psychologist for your own mental health care.

Quote
magnetic icon

I have a few on my fridge holding up paperwork

Quote
I have some acid acute pains sometimes on spinal cord on my back inside the skeleton...

See your medical healthcare provider. Could be nothing.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: virgo313 on January 01, 2022, 12:07:13 pm
Don’t think spinal pain is related to poz. I change my mattress & now I have less pain. Very often it is related to sleeping conditions when back hurts.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 04, 2022, 09:23:02 am
Guys hello there...
I'm really mad about me.
I have made a mistake.
Or maybe it was misunderstood here.
I didn't connect because I don't have the knowledge and I just asked if there any ideas so I could help and be helped with info from your experience.
I need to edit a comment ANd cannot find where is it !!! Also if I have said anything offensive or against pers data please show me, I'm ready to pay the consequences
..
Wish you all happiness for new year...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 04, 2022, 09:30:07 am
In my last message of today I can see a "Modify" choice... I'm my 5 days comment I cannot see such a choice. Does anyone know please??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 04, 2022, 09:38:27 am
Not sure why you are writing in Caps or you think there is a personal data issue?

Anyhow, the edit function isn't available by design. It's only for a limited time and you can't edit a post after it's been read and replied to by others.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 04, 2022, 09:44:14 am
Not sure why you are writing in Caps or you think there is a personal data issue?

Anyhow, the edit function isn't available by design. It's only for a limited time and you can't edit a post after it's been read and replied to by others.
I'm sorry I forgot caps enabled..
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 04, 2022, 09:47:07 am
Anyways There is need to change.

I did mistake and MUST EDIT OR DELETE..
MINE..
Not others' comments ... But mine yes ..

By reporting??
Can I do??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 04, 2022, 10:12:20 am
Hiya,

Quote
We do not allow the deletion of anything you post in these forums, so think before you post.

Now, with that being said, I am willing to go back and edit posts for members that contain things like personally identifiable data such as photo's or email addresses/names/addresses or phone numbers etc.

So if the post contains identifiable data, please PM the details of the post and I'll edit that data out.

Best, Jim.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 19, 2022, 12:31:29 pm
Hellooo good evening guys.. how are you all???
Wishing good year and happy year ...
Are you all fine??

I would like to discuss about this new UCLA findings??
I promised to not read and I did it for months.
But now I was in holidays season so I wanted)felt the need to know what's new??

Any hope at the end of the tunnel??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 19, 2022, 12:40:44 pm
What findings? Do you mean SUW133
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on January 19, 2022, 08:12:53 pm
I wanted)felt the need to know what's new??
Why? Do you think you won't hear about it in the news or on social media? Do you think your Doctor isn't going to administer the cure to you if and when it's developed?

I hope you realize that when a "miracle" treatment or the cure is developed it'll be all in the news (including poz.com, thebody, etc), even long before it'll actually be available.

Looking at all this kind of information about any possible cure isn't going to get the cure to you any faster than I'll get it myself; but it will get you a lot of stress, unnecessary worry, and emotional turmoil that I don't have (and haven't had in the 38 yrs that I've lived with HIV)
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 19, 2022, 11:42:54 pm
What findings? Do you mean SUW133
Hey Jim , nice to see you here again...how are you? No, I know it isn't new , I mean the suw133.
Just wondered if it brings some hope...
Of course , as Leatheman told, if it's a cure ever we will all know.
Just saw an article about this on the recommended to read articles and wanted to share and hear thoughts.
Wishing you all good day.
I'm having a sore throat from yesterday , maybe because of my son who had it too few days ago...and feeling a bit upset.
Good morning ☀️ guys
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 19, 2022, 11:45:11 pm
and haven't had in the 38 yrs that I've lived with HIV
Really Leatheman?? I thought you had told us here you have been living with it for 29 yrs, maybe thirty this year...
Wish you more GOOD more 38
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 20, 2022, 03:34:22 am
Hey Jim , nice to see you here again...how are you? No, I know it isn't new , I mean the suw133.
Just wondered if it brings some hope...

Suw133. Well, good news for the mice, although we made them sick to start with :-\ Suw133 has been around for years and I'm not a mouse.

Although on one hand, the learnings are always interesting, another part of me thinks given the issues this planet faces we should for our own good focus on other priorities. Anyhow, at this time Suw133 does not mean anything to me as a person living with HIV.

However, I'll update the Suw133 thread if anyone wishes to discuss it. https://forums.poz.com/index.php?topic=67702


I'm having a sore throat from yesterday , maybe because of my son who had it too few days ago...and feeling a bit upset.
Good morning ☀️ guys

Sorry to hear you and your son have been feeling unwell and I hope you both feel better soon.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 20, 2022, 04:17:26 am
This is worth repeating.

Looking at all this kind of information about any possible cure isn't going to get the cure to you any faster than I'll get it myself; but it will get you a lot of stress, unnecessary worry, and emotional turmoil that I don't have

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 20, 2022, 07:53:10 am
Thanks guys...
Good evening..
Jim , this sore throat and GH GH move to clean throat is really really bad.. dontou have it?? I had once again in October, lasting only two days... So I don't know.
In past I had once a year but lasting for 3-5 days.
Now more times , but less period...
😌😌😌
Wish you all the best...

Here we will have -5 in my city in two days! How is the weather in Ireland?

Also Leatheman , where do you live??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 20, 2022, 08:17:37 am
Jim...

I also read an updated article from Very well health.

It says this :
""For most people who are treated early, the CD4 count will return to normal levels (500 or above). For those who delay treatment, the CD4 count may never fully recover, leaving that person vulnerable to opportunistic infections.
Studies have shown that starting HIV therapy with a CD4 count under 200 reduces life expectancy by an average of 8 years compared to someone starting at a CD4 count over 200.""

Is this an outdated article or with outdated information?

Has anyone here ever seen a person starting treatment with lower than 200 and reaching more than 500??

Thanks guys
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 20, 2022, 08:18:17 am
https://www.verywellhealth.com/how-long-can-i-live-after-getting-hiv-48889
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 20, 2022, 08:26:58 am
Jim...

I also read an updated article from Very well health.

It says this :
""For most people who are treated early, the CD4 count will return to normal levels (500 or above). For those who delay treatment, the CD4 count may never fully recover, leaving that person vulnerable to opportunistic infections.
Studies have shown that starting HIV therapy with a CD4 count under 200 reduces life expectancy by an average of 8 years compared to someone starting at a CD4 count over 200.""

Is this an outdated article or with outdated information?

Has anyone here ever seen a person starting treatment with lower than 200 and reaching more than 500??

Thanks guys

We have already answered this and had long conversations about it in your thread  ;)

You are going to back to asking questions that have already been answered just asking them in a slightly different way.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 20, 2022, 08:29:43 am

Here we will have -5 in my city in two days! How is the weather in Ireland?


The last few weeks it's pretty warm for Ireland and we have had some sunshine. Some days we even had 12/13 degrees celsius, although, had some frost the last 2 days and the temperature is currently 5 degrees celsius
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 20, 2022, 10:49:59 am
So I will go back again to previous replies to find .. because really I don't remember if someone starting with lower than 200 can have again 500+ with new modern haart ..
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 20, 2022, 10:51:22 am
Here too...it was today close to 20 but from tomorrow we will have a frosty week with temperatures reaching in centre of Athens about -2-0 degrees.
Hugs and bye
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 20, 2022, 10:51:34 am
Here too...it was today close to 20 but from tomorrow we will have a frosty week with temperatures reaching in centre of Athens about -2-0 degrees.
Hugs and bye
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on January 20, 2022, 01:20:17 pm
Really Leatheman?? I thought you had told us here you have been living with it for 29 yrs, maybe thirty this year
ah! sometimes my timeline seems screwy but that's because I (mostly) know when I was infected. I've been taking meds since December 1992 when I was diagnosed (that was a crappy Christmas present for me and my first partner who got his results the following month), so that's been 30 yrs that I've been taking meds this upcoming Dec. But I'm also pretty sure, looking back in retrospect, that my first partner was infected 2 yrs before we got together and that's how I was infected in 1984 - and that would be the 38 yrs of living with HIV coming up later this year in November.

Has anyone here ever seen a person starting treatment with lower than 200 and reaching more than 500??
Oh gosh yes! Me, my husband, over a dozen friends, tons of people I've met doing peer support and advocacy work, and bunches of people who are long term survivors (as in pre-HAART long term survivors). All of the people I'm thinking about all had cd4 counts <200 (most down in the teens). While these people all have cd4s >500 now, I do know a few people who haven't reached 500.

Heck, I just finally joined this bunch last year and it still freaks me out to have such a large cd4 when I spent probably 15 yrs thinking 350 was about as high as I would ever get. Six months ago, I hit 742! My husband and I share our doctor appointments and at our appointment last week, my husband outed me to our doctor about worrying when my counts were so high and claiming that the lab results HAVE to be wrong. Hehehe I felt much better when I found out my cd4s were back in my new "normal" range and were back down to 523. Our funny, funny doctor even left a note saying he fully believed this result was not a lab error. ;D ;D ;D

Just remember, as long as your cd4s are >200, it doesn't matter how many you have. It just matters that they work!  ;)

Also Leatheman , where do you live??
well, while the last couple of days have felt like I was back in Ohio where I lived with my first 2 partners - with snow on the ground, cold biting wind, and having to run the furnace all day - I'm living back outside my hometown of Charlotte, NC, in a little town in upper South Carolina. Several of my Ohio friends have called to kid me about our winter "storm" (about 1/5 inch of icy snow); but when I heard about the 18 inches of snow up in Cleveland, while the remaining snow here should be finished melting away with the 40 degree weather and rain, I was again reminded of why I quit leaving up North with the Yankees. LOL
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 20, 2022, 03:06:53 pm
Thanks for your nice answer. .I like communication.
I promised to quit reading. I did it. Now I came back after a month off. Need to know what happening around...

Anyways I don't think that it was lab error too...your 7hndr+

So finally do you or don't you support Yankees.

Me as you understand support Yiannis Adetokoumpo 👊🌷🌹🙏🏽
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on January 20, 2022, 07:55:41 pm
So finally do you or don't you support Yankees.
yankees as in baseball team? No. I'm a Cleveland Indians/Guardians fan
yankees as Americans who live in the Northern states? yes, I have loved many of them, especially my 2 deceased partners and a lot of friends I left behind when I moved.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 21, 2022, 04:21:45 am
Hey.. food morning... Can I ask something about AGT103??
When they say "AGT hopes to have a 'functionally cured patient by next summer' , do they mean summer 2022 or 2023??

Also , they tell , that a 15 year follow up is required bumy FDA and is mandatory. By this do they mean , that if a cure is found by next summer' , so the cure will be available (If the follow up is ok) after 15 years , ie the soonest at 2037??
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 23, 2022, 01:55:47 pm
Hey guys .. can anyone answer me this please??

I admit this Xmas season , I ate like no tomorrow.
The most cholesterol , sweet and bad saturated foods.

So I started searching about cancers and us as a group.

I found although a 20 year old being infected can expect to live until 70 , however cancers can come 10-15 years earlier than what they would come related to our negative peers.

Is this still data from old studies, or with the new treatment can we expect bit better outcomes??

Please don't tell me , we have talked this topic again.
Now I ask something clear and specific.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 23, 2022, 02:26:03 pm
Quote
Please don't tell me , we have talked this topic again.
Now I ask something clear and specific.

We have thought and we have provided clear and specific information.

End of the day, you live with HIV, and the treatment you are currently taking belongs to the most modern treatment in suppressing HIV. Nothing more can be done at this stage, so no point stressing about it, end of story!

Trust me, I could have wasted two+ decades stressing about it, or I could have lived my life, and I chose the latter, and so can you. I know we spoke face to face on zoom about this as well.

Sure, we a group risk, well to start, that's a total shit bucket, like the rest of humanity, regardless of HIV status. Anyhow, we all have different backgrounds, treatment histories for our health issues, lifestyle risks, and co-modalities that need to be considered.

So, as a group considering the above, we have somewhat increased risks for certain issues, but we also have more monitoring that benefits us. Finally, at the end of the da,y nobody has a crystal ball. Also, you can reduce your risks for issues like cancer as we have discussed at length as well. Overall things are more treatable nowadays and overall despite our increased risks as a group it does not change the projected life expectancy as a group is near enough the same as out HIV negative peers.

No offence, but I really am considering a ban for you would be in your best interest. It would be a first for someone living with HIV on these forums who has not breached any "defined" rule and it's not something I can decide on my own, I would have to consult others, but I do wonder if prehaps it's in your own best interest as clearly, to me, the forums are not helping you.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 23, 2022, 04:35:23 pm
I am not offended by this. I have learnt that life is difficult and hard. Universe is against all of us atomically...so we have to learn to live with this , like French say Cest la vie.
Why do I tell this?
By a ban to me, I will only feel a group, a team that I feel I belong to, rejects me because I ask a lot , because I want to know more...I will only feel this as a punishment, but it's welcome if universe decides this... I will lose one more door to people who felt connection with but I don't really understand the reason...
I didn't offend, I didn't blame , I didn't use bad words... By banning someone who asks a lot, what is the benefit?

You , I mean many here, asked me to live my life... I'm really doing this. With my hobbies , work , family everything. Some weeks I have not even time to search for such things.

Anyways, the only reason to ask many things is that I only want to know in what degree I can relax.....

For example.. you say nowadays most cases are treatable. But in the article I told you was written, that for us , even when find something early it's a bit more difficult and less efficient to treat it because of our initially damaged system.

And I asked if this was with the old treatments or with the new ones too?
If someone explains me what is bad by asking something rational like this, I will next time think not twice but ten times before I ask something...

Anyways.
I'm sorry if I bothered you.
I'm really sorry .
I will really disappear for until April when I will have my 1+3+6 months test...

Good night guys.
🙏🏽🌷
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 23, 2022, 04:59:07 pm
Quote
I am not offended by this.

Good because trust me I am not worried for a single second if you are offended.

Quote
By a ban to me, I will only feel a group, a team that I feel I belong to, rejects me because I ask a lot , because I want to know more...I will only feel this as a punishment, but it's welcome if universe decides this... I will lose one more door to people who felt connection with but I don't really understand the reason...
I didn't offend, I didn't blame , I didn't use bad words... By banning someone who asks a lot, what is the benefit?

Well, it's not about rejecting you or punishment, it's not about how many questions you ask. It's about caring about you and encouraging you to seek professional support as more than a few members have already suggested but you seem to be against it.

If I wanted to punish you then I have many ways of doing that and a ban is not one of them.

Quote
You , I mean many here, asked me to live my life... I'm really doing this. With my hobbies , work , family everything. Some weeks I have not even time to search for such things.

Anyways, the only reason to ask many things is that I only want to know in what degree I can relax.....

Some weeks, I go years despite being here every day without thinking about my own HIV status. You are not there yet.

Quote
For example.. you say nowadays most cases are treatable. But in the article I told you was written, that for us , even when find something early it's a bit more difficult and less efficient to treat it because of our initially damaged system.

Asked and answered. Not only that but I have posted this stuff about this in the welcome thread.

You can't change what has happened. You are living with HIV and you can manage the risks, now as a group, we have near-normal (average) life expectancy dispute issues along the way.

Quote
And I asked if this was with the old treatments or with the new ones too?
If someone explains me what is bad by asking something rational like this, I will next time think not twice but ten times before I ask something...

Sure, this has been explained as well.

But in plain language, the old cohort belongs either to groups that no treatment was available for a long time or older treatment and even then they waited to start treatment when you had AIDS and I mean the classic sense of the word, shit treatment options and CD4 totally fucked + IO's.

these groups that survived have in studies shown to have a few years fewer life expectancies as a group, but even then if take into account certain issues it's less than 5-8 years less. 82 - 5 is 77 with treatment is good compared to death on average within a few years.

Also, let's for argument sake say you would live 5 years less, well that's not bad, is it? So enjoy it and stop stressing about it.

Treat your HIV, attended check-ups, treat any issues that occur early, and cut out any bad habits, live your life,
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on January 23, 2022, 08:41:50 pm
first I'd like to add a few things to what Jim posted earlier

Quote
Anyhow, we all have different backgrounds, treatment histories for our health issues, lifestyle risks, and co-modalities that need to be considered.
since gpapadop91 mentioned cancer, it should be noted that many cancers are more likely because of genetics. So instead of looking at HIV for potentially "giving" you cancer in the future, blame your parents and grandparents. In the long run, it's their "fault".  ;)

Quote
the projected life expectancy as a group is near enough the same as out HIV negative peers.
actually gpapa, some studies are showing that people living with HIV, who receive regular health care, remain adherent to meds, and have cd4>200, may actually be living longer than their HIV- counterparts. How you ask? people living with HIV are more likely to access health care more often, are monitored more regularly, and are diagnosed and treated sooner (on other issues) therefore living longer than counterparts who don't have the same regular monitoring

I am not offended by this. I have learnt that life is difficult and hard. Universe is against all of us atomically...so we have to learn to live with this , like French say Cest la vie.
while I certainly agree that life is difficult, I don't agree that the universe is against anyone. The universe doesn't care. Your life is based on your upbringing, your income, and what choices you make. Something in your life you don't like? Then work to change it. Learn a new skill, get medical help, be a more caring person, work hard to change the things about you or your situation that you don't like.

By a ban to me, I will only feel a group, a team that I feel I belong to, rejects me because I ask a lot , because I want to know more...I will only feel this as a punishment, but it's welcome if universe decides this
Again, the Universe isn't deciding anything. It's not your questions, it's you not listening to us. This is 2022 and HIV is a highly manageable illness. Daily meds suppress HIV and patients can go on to live full, long lives. I can certainly understand that you want to know more about this disease you have - so focus on the subjects of how to be adherent to your meds, eating healthy, exercising, and doing things to be a healthier person. While you're worried about possible HIV-related issues (that may not even affect you as someone who was able to start with the most recent meds), things like high blood pressure, bad cholesterol, diabetes etc are much more likely to end your life than anything like HIV or cancer.

Your belief that something HIV-related, sometime decades away in the future could end your life prematurely is what is being rejected. Our hope is that you can replace your unfounded fears about possible future outcomes with taking care of your mental and physical health in the here-and-now.

For example.. you say nowadays most cases are treatable.
The only patients not treatable are the people who are not diagnosed or treated until too late. Many people who are literally on their death beds have been brought back to life by HIV meds; but sadly not all of them. Those are the people who simply weren't treated in time - this is clearly not your situation and should not be concerning you.

that for us , even when find something early it's a bit more difficult and less efficient to treat it because of our initially damaged system.
actually that's completely backwards. While in the past this kind of thinking might have been a little more true, these days for HIV+ people early diagnosis of other issues often makes it easier to be treated with a much higher rate of successful treatment.

Quote
You , I mean many here, asked me to live my life... I'm really doing this. With my hobbies , work , family everything. Some weeks I have not even time to search for such things.
while I have researched medications in the past (things were changing rapidly in the 90s, and staying on top  of the latest medications is part of why I'm still alive after starting meds 30 yrs ago); NEVER have I ever done research about the longevity of life or a cure. Those things are completely unpredictable and completely out of my control and therefore none of my concern. maybe, because HIV is very complex virus, if I was a microbiologist or something I would care more; but as a patient, how long I live is based on how healthy I can make my body (that's why at almost 60, I'm in the gym everyday ;) ) and whether a cure happens or not really doesn't matter as I've got HIV successfully suppressed right now.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 24, 2022, 04:10:09 pm
Good because trust me I am not worried for a single second if you are offended.
Hey Jim. First of all thanks for all this. I really appreciate your time and it's helpful believe me. More than you can understand.
Secondly , it's you yes and I know your style but I'm only almost month more than half year. Not a year yet. So I'm exploring, I want to know. By getting banned , it's not a way if you think so to put someone to seek help ... However believe me I did it and started solving issues from beginning of my life with specialist. I have already done 7-8 sessions .. trying yet... So please understand me I need motivation , not fear ... And I have it from all of you here.

Anyways believe me I have accepted my case. But for me confusing information make me search more.
For example you say 82-5 , 77 is something bit different than the "same life expectancy but much less healthy years" I read on aidsinfo website.

To make long story short .. I'm just asking the specialists,you, and who are in my team to get to know. If I don't know how I will decide what should I do?

You think I don't live my life? This xmas I ate what I didn't ate all years together. 😂🤣 Enjoyed too much. Anyways we will talk about this when I will be in Ireland.

Generally , if we find something soon , can we treat it the same effectively like in neg peers?

Goodnight guys from the totally snowy Athens.
Bye
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on January 24, 2022, 04:24:12 pm
Hey Leatheman how nice you talk... This is maturity and kindness too. If I hadn't you and Jim , but others who wrote me here I love them as well... I don't know what I would do.
Invaluable information or help... Thanks.... Virgo for example the other member with a cat tiger STH like this profile picture.

Letaherman, my hematologist she told me a month after diagnosis to avoid strength exercises at gym and recommended for my case and group a fast with rhythm walking and same time when I walk to exercise abs...

Because I would like to do strength exercises but im afraid to give excessive amount of tiredness to body..

You have right. Cholesterol I have to check again because I can see it's a bit elevated...the bad one..
Haha

Guys , love you all.
Kisses
Sincerely appreciateful to your help.
Bye
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 24, 2022, 04:29:23 pm
A ban would be because letting you continue here would be not in your best interest.

Quote
If I don't know how I will decide what should I do?

See that's the issue. You do know and there is nothing really to decide in relation to the questions you have. Take your meds, go to check-ups and live your life, end of story.

Quote
For example you say 82-5 , 77 is something bit different than the "same life expectancy but much less healthy years" I read on aidsinfo website.

Asked and answered already.

Quote
Generally , if we find something soon , can we treat it the same effectively like in neg peer

Not sure what you mean?

We already have something, it's called ART (HAART) and with that, we should already treat HIV as a manageable condition like so many conditions people have regardless of HV status.

Quote
You think I don't live my life? This xmas I ate what I didn't ate all year together. 😂🤣 Enjoyed too much. Anyways we will talk about this when I will be in Ireland.

Not yet. You still give your HIV status far too much control and power over you.

Quote
I have already done 7-8 sessions .. trying yet... So please understand me I need motivation , not fear ... And I have it from all of you here.

Genuine question, are those 7-8 sessions with a psychologist? How is that going?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on January 24, 2022, 08:10:02 pm
Letaherman, my hematologist she told me a month after diagnosis to avoid strength exercises at gym and recommended for my case and group a fast with rhythm walking and same time when I walk to exercise abs...
.
Blood test , done at 8 of July , a month (28 days to be accurate) after starting my treatment with Descovy and Isentress , showed now
....
UNDETECTABLE VIRAL LOAD
well, that seems like bad advice. I went back through this long thread and saw that within a month of treatment you went from a high VL to undetectable with rising cd4s above 200. You're quite the lucky person. Most people can only hope to reach successful treatment in that short of a time. With those kinds of numbers there's no way you shouldn't be getting back to your normal life and normal exercise. You know how best your body feels and can improve your exercise routines and limits as you feel.



Generally , if we find something soon , can we treat it the same effectively like in neg peers?
I took this to mean that if some other illness was diagnosed would/could it be treated as effectively as with HIV- people?
Yes. While HIV+ people may have slightly higher rates of some diseases, after HIV is suppressed, these diseases would be treated as well as for any people. Being HIV+ doesn't make any other disease worse or treatment for those diseases any less effective.

You think I don't live my life? This xmas I ate what I didn't ate all years together. ???? Enjoyed too much. Anyways we will talk about this when I will be in Ireland.
mmmm the holidays. I baked and iced sooooo many sugar cookies! Eight dozen went out to friends and family. Oh and I ate a bunch too! Unfortunately for my friends (and my poor husband), I am GREAT at making desserts. I cook everything but desserts are my forte.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on January 25, 2022, 03:45:34 am
Quote
Anyways we will talk about this when I will be in Ireland.

Sure thing and this week they dropped the COVID restrictions so pubs etc are open again.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on February 06, 2022, 12:30:27 pm
Hello guys...

How are all you?

I just found out about this strain causing 3-4 times more higher viral load than hiv poz peers , so in my head it's some kind of connection between my initial viral load to this variant.

Still , new medications are effective without the variant being resistant to treatment so it's said no need to new meds for this strain is required...

Hope you are doing well...

https://www.npr.org/sections/goatsandsoda/2022/02/04/1078035844/discovery-of-hiv-variant-shows-virus-can-evolve-to-be-more-severe-and-contagious?ft=nprml&f=1078035844


Kisses
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on February 06, 2022, 03:56:08 pm
Yeah, seen this over the last few weeks, not really news though and there are other strains with rapid progression within 2-3 years, although I'll open a thread for it and you don't have this particular strain.

How are you feeling generally?

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on February 07, 2022, 01:32:21 pm
Hello Jim 👋🤗
Thanks for asking , I'm doing well , really ..
Only some articles recommended by chrome can sometimes make me a bit thoughtful....
However I don't know if I have this strain or another. The trans girl who gave it to me is very famous and popular in western countries and Netherlands too... So ...
But anyways I'm feeling bwell.
Also feeling fine and hopeful and optimistic with the progress have been made (is it correct grammatically?) with cure , I will paste the link...

https://www.labiotech.eu/in-depth/hiv-cure-research/

And Jim what about you?
Today my friend this girl who started working in Newbridge told me in the morning it was totally freeze the weather...
How is it? Really cold??
Here too today...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on February 07, 2022, 04:16:51 pm
I think you need to adjust your chrome settings if it's recommending so much crap, can't be healthy to have HIV publications popping up all the time, and you didn't aquire HIV from the trans woman, at least not from the activities posted here  ;)

Anyhow, moving on from that closed topic, I'm glad to hear you are otherwise doing well.

Quote
Today my friend this girl who started working in Newbridge told me in the morning it was totally freeze the weather...
How is it? Really cold??

To be honest, I think it's the mildest winter I can remember. It was between 4-11 degrees Celsius today.

P.s

It depends on what you are used to.

When I was a kid winters for me often enough included temperatures of minus 16-20 degrees celsius (3 degrees Fahrenheit) and we went ice skating on the rivers and lakes. So 4 degrees Celsius isn't cold for me

However,  if are from a warmer or dryer climate, I suppose it's going to feel cold.



Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on February 07, 2022, 07:55:10 pm
Quote
"Nobody should be alarmed," Wymant says. "It responds exactly as well to treatment as HIV normally does."

There's no need to develop special treatments for this variant, he adds. It shows no signs at all of resisting medications, as some HIV variants do. But because the variant moves quickly, people need to receive medicine as fast as possible.
so that's all still ok news for more developed countries. Most developed country have some sort of healthcare program, and most if not all have plans within that program evaluating their own HIV looking for ways to reduce the spread. Included in that kind of program are mandated measures that try to shrink the amount of time from diagnosis to prescription and through to undetectable viral load.

The Ryan White Program in the USA uses the Continuum of Care to evaluate the progress to eradicating the disease, through both prevention and through treatment.

these steps through the continuum of care are:
diagnosis of HIV infection
linkage to HIV medical care
receipt of HIV medical care
retention in medical care
achievement and maintenance of viral suppression
https://www.hiv.gov/federal-response/policies-issues/hiv-aids-care-continuum

In the past, the thought was to wait on treatment until a patient reached a certain point; but time has shown that getting started on medications ASAP is the way to go to ensure HIV does the least amount of damage to a patient's immune system. No matter from when a person is infected (or what strain or what their viral load is) to when they are diagnosed, the goal is to get the patient into medical care, prescribed meds and monitored for reaching undetectable as soon as possible.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on February 12, 2022, 12:58:25 pm
Good evening and greetings to everyone here...
Wishes for happy weekend
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on February 12, 2022, 05:13:20 pm
Good evening and greetings to everyone here...
Wishes for happy weekend



         ojo.         Hello there!…same to you…hugs
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on February 25, 2022, 03:00:42 pm
Hi guys.
Haven't been here for a long time!!!

What if crazy Putin starts a 3ww?

Will we run out of meds?
😳😳😳
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on March 29, 2022, 09:39:47 pm
Good morning guys how are you??
A long time to write and hear from you.
I'm having 3rd time a bronchitis and cold within a 6 month period.
My son had pulmonary upper respiratory flu for 2-3 weeks so when he became better I put out masks because I felt I'm ok, I'm strong , so I got it 😜😂
And I couldn't sleep more from cough and woke up to boil a tea/camomile and thought let's see how is everyone...
Hugs brothwrs
Anyways how is everyone?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on March 30, 2022, 03:19:03 pm
Almost two months and didn’t hear news from any of you… hey give me signs anything for everyone is fine…
🙏🏽💪🏽
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on March 30, 2022, 03:31:35 pm
Sorry to hear about bronchitis and I hope you and your son are feeling better.

Almost two months and didn’t hear news from any of you… hey give me signs anything for everyone is fine…
🙏🏽💪🏽

No news. Working, been sick (am sick), been busy these last few weeks.

You are welcome to keep everything in one thread but you might want to consider opening up new threads if it's a new topic or an off-topic thread if it's not related to HIV to get more engagement.  Just a thought
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on March 30, 2022, 08:41:09 pm
I'm having 3rd time a bronchitis and cold within a 6 month period.
My son had pulmonary upper respiratory flu for 2-3 weeks
ugh. sorry to hear about all the illnesses. hope everyone gets well soon!

any of our sneezing, congestion, and watery eyes right now is from pollen. I miss living in Ohio sometimes (I even miss the snow.......sometimes) because the cold kills a lot of bugs and Spring is fast and not so potent. Here in the Carolinas, everywhere is coated in a yellow film of pine pollen and it won't be long until I need to swim in OFF mosquito spray or risk being eaten alive.

been sick (am sick)
yuck. all you people should learn to avoid germs better.  ;)
feel better soon too!
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on March 31, 2022, 04:27:44 am
yuck. all you people should learn to avoid germs better.  ;)
feel better soon too!

 ;D

Ah yeah, antibiotics and bed-rest for the week.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on April 03, 2022, 05:34:38 am
Hi guys .. sorry to bother you again.

Jim get well soon my friend ...

Please 🙏🏽 help I think it's seroconversion related .
I was found two days ago with d dimer level of 1,25 with cut off limit of 0,5

I am searching and seeing is possible after seroconversion the coagulation.

Do you mind any cases with the new treatments?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on April 03, 2022, 05:46:37 am
D-Dimer test.

Presume it was for a reason, the cough prehaps. Anyhow, when are you following up with your doctor or have you already and what did they say.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on April 03, 2022, 02:38:59 pm
Hey there thanks for asking ,
Also on Friday I was found with

4400 WBC of 29% lymphocytes
CRP 11 with cut off 5 (chronic inflammation or maybe can this explainsned by the bronchitis I had last week?)
D dimer 1,3

.....

I talked with my hiv specialist doctor
He told me not panic and follow those doctors recommendations about checking repairatory blooding scintigraphy, .

Then searching the net I also saw that ddimer as well as Crp is used as biomarkers of measuring the inflammation...

We will see
Of course I will follow up with anything new and let you all know.

Anyways I really feel well...
I just had started overdoing with bad eating habits so last two weeks started again a diet and I'm in losing extra pounds mode

Kisses and hugs to all of you guys.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on April 04, 2022, 01:32:19 am
Glad to hear you feel well.

Bronchitis is caused by a virus, like the common cold or flu or a bacterial infection resulting in inflammation. So sounds like they checked for a colt following your recent illness and coughing, had a positive indicator and are now going to investigate further.

I'm sure they can explain this more when you talk to them next, but do keep working with your doctors, try to relax and keep in mind that not everything is HIV related and you will get common illnesses from time to time just like everyone else in life.
 

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on April 09, 2022, 06:39:28 am
Μy friends hellooo
Can I ask you something please ?
The last month , I have between hair and eyebrow a redness on my skin about a coins surface in size, I think it's because of inflammation because in my recent blood tests (not the regular 6months tests which I will have it next week) I was found with CRP 12 !!!
Is it common such a big number while on art?
I confess last month I ate pizzas , chocolates , sweets , ice creams , all known to increase inflammation....
It's so red I can show you pictures today after all day yesterday hydrating this place ....
Don't tell me to relax , how can I relax , being positive with 12 CRP , with 50 millions initial VL , with one functional working kidney ....
Anyways , everything as info from your experience is welcome my bros...
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on April 09, 2022, 07:20:10 am
Stop eating crap, it's bad for you regardless of your HIV status.

The rest are all either irrelevant or things to discuss with your doctor although considering you were recently sick some inflammation would be expected but the results or potential causes need to be discussed with your doctor. Coin sized surface issues could be a number of things that again you would need to talk to your doctor about.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on April 09, 2022, 07:44:33 am
Hey Jim thanks , really thank you.
I really stopped it.
I will follow very strict eating habits onwards.
Yesterday morning I ate 3 chocolwaffles and two chocolate balls with coconut pieces
Day before I had eaten chocolate cake with liquid chocolate inside and two I've cream balls
Also dried fries ... Oufff...

Anyways , a crp of 11,5-12 is it too much? Cardio doctor told me nothing to worry about its usual for many people...

In a month I will try to write here I didn't eat crap at all.
Boiled only

Any tips please for avoiding inflammation?

But please , understand me , how shouldn't I get stressed with such a picture of coin sized inflamed skin? 
By talking number of things , can I exclude cancer. ????
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on April 09, 2022, 08:01:18 am
How to send a photo as attachment here?
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on April 09, 2022, 08:13:44 am
Quote
But please , understand me , how shouldn't I get stressed with such a picture of coin sized inflamed skin?

No need to get stressed. It could simply be ringworm or something innocent that needs a cream but the only way to know is to see your GP.

You are going to have common heath issues in life just like everyone else. Get used to it as the only cure is being dead.

Quote
Anyways , a crp of 11,5-12 is it too much? Cardio doctor told me nothing to worry about its usual for many people...

Sounds like you have the answer.

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on April 09, 2022, 08:27:25 am
Οnly cure is dead 🤣😂😇🤣😂🤣😂🤣🤣🤣🤣 a
Thanks for this ☺️
Haha
Is everything fine in your lives?

What else? How is weather there?? ,🙏🏽🌺💪🏽 Good afternoon
And don't forget me , send me sometimes when you can please , all of you.

Bye guys
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on April 10, 2022, 11:04:23 am
What else? How is weather there?? ,🙏🏽🌺💪🏽 Good afternoon
And don't forget me , send me sometimes when you can please , all of you.

Bye guys

Grey and wet, it's Ireland. Anyhow, everything is fine here.


How to send a photo as attachment here?

https://forums.poz.com/index.php?topic=72951.msg761470#msg761470

Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on April 11, 2022, 01:30:29 pm
Thanks Jim , 2 days to have my 10 month tests , a bit stressed... Will inform you
Hoping Isentresss and Descovy out in deep sleep mode this fucking retrovirus
And also gained some 30-50 more cd4s than last October

Jesus 🙏🏽🙏🏽🙏🏽
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Jim Allen on April 11, 2022, 09:58:41 pm
Thanks Jim , 2 days to have my 10 month tests , a bit stressed... Will inform you
Hoping Isentresss and Descovy out in deep sleep mode this fucking retrovirus
And also gained some 30-50 more cd4s than last October

Jesus 🙏🏽🙏🏽🙏🏽

No need to stress, it will be fine, keep us posted.
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: gpapadop91 on May 13, 2022, 02:23:19 pm
Helloooo dears
How are you ??? I wish you all have good lives ,,,
I want to share with you a tip that my soul doctor gave me today ,,, when I'm feeling bad or stressful I should be compared to poorer people who are jobless or have bad health issues so we can feel relaxed and stress free ,,, I can catch my self that it works for me at least ...

Unfortunately I missed my scheduled lab tests because I was delayed in my appointment
So they gave me a new date for 30 of May
I hope 🤞 we wil be fine ...
Kisses and hugs 🤗
Please keep posting here , I need to feel all of your presence here as often as you can leave a comment or a greeting guys

Bb
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: Tonny2 on May 13, 2022, 02:56:33 pm



          ojo.       Hi!, don’t get me wrong but, I’m happy not “seeing you” around here that often, it tells me you are taking control of your life again, good for you!!

     ojo

https://youtu.be/UZVyzCwGVyE

I hope you can watch this video, it’s in Spanish but I think but just watching it you, all of us, get the message. There are people where are in worst situation than us and still move on with their lives…hugs


@jim moderator, if the video isn’t available to watched, maybe I did something wrong, could you help me?, thx
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: daveR on May 14, 2022, 01:30:07 am
Helloooo dears
How are you ??? I wish you all have good lives ,,,
I want to share with you a tip that my soul doctor gave me today ,,, when I'm feeling bad or stressful I should be compared to poorer people who are jobless or have bad health issues so we can feel relaxed and stress free ,,, I can catch my self that it works for me at least ...

Unfortunately I missed my scheduled lab tests because I was delayed in my appointment
So they gave me a new date for 30 of May
I hope 🤞 we wil be fine ...
Kisses and hugs 🤗
Please keep posting here , I need to feel all of your presence here as often as you can leave a comment or a greeting guys

Bb

Good to hear you are doing OK. The tip you shared is a good one. A few pages back on your epic thread I mentioned mindfulness practice. I find it useful, an app I use iw Waking Up by Sam Harris. It has guided meditations and also a theory section with discussions from himself and various people. In one of those lessons he recommends people to think of the worst thing that hasn't happened to them yet, living in a war zone, fatal diagnosis, and then imagine what the people who suffer from these problems would give to swap places with you. It really puts our positions into perspective when you realise just how lucky we are compared to others if HIV is our only issue.

Dave
Title: Re: 48 million viral load during acute hiv with fever and moderate flu like illness
Post by: leatherman on May 14, 2022, 08:54:45 pm
when I'm feeling bad or stressful I should be compared to poorer people who are jobless or have bad health
I have a similar philosophy - but the comparison is to events in my own life.

For a long time, the worst day in my life was when I suddenly had to leave my out-of-state college mid-year to move back home. On my bad days, I would say that at least it wasn't as bad as "that" day.

But then my first long term partner died, well, that day became the new measure of how bad the worst day was.

When my second partner was in the hospital, I got through a LOT of bad days because none of those days were as bad as the day my first partner died. Well, until my second partner died. Certainly now, there is absolutely nothing that could be as bad, no matter how bad things might get, than the day I had to keep living while not 1 but 2 partners were dead.

of course, right now I am risking having even a worse "worst day", but as of today, I'm happily still with my 3rd long term partner. Who knows? with some luck, maybe my husband will outlive me and I will never have experience anything worse than the day 2 partners were dead.

So that's how I survive the really bad days, by realizing that no matter how bad it is that day, it isn't as bad as my worst day.

To get through every day though, having been hospitalized with AIDS a few times, I just remember my motto: Any day I'm not in the hospital, no matter how bad, is still a GREAT day. and if you don't believe that, all I can say is try not dying in a hospital with a week ;) , and then let's talk. At that point, I'm sure we'll both agree that not being in the hospital is awesome! :D :D :D :D