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Welcome to the POZ Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

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Recent Posts

Pages: [1] 2 3 ... 10
1
Estoy infectado? / Re: Fear of getting test for hiv after taking pep for 28 days
« Last post by leatherman on Today at 10:43:11 am »
Haz la prueba.

Eso es todo lo que puedes hacer. Hablar o preocuparse por los resultados no contribuye en nada a obtenerlos. Y el resultado de la prueba es la única forma de conocer su estado.

La PEP es muy eficaz. Como medicamento contra el VIH, la PEP NO influye en el resultado de una prueba de VIH.
2
Estoy infectado? / Fear of getting test for hiv after taking pep for 28 days
« Last post by shiv3554 on Today at 10:02:46 am »
Hello sir

Pls I m freaking out to take a test for hiv after taking
Having broken condom ( for 20 second)
sex a month ago
I took pep with in 30 hrs of exposure
And competed it with 28 days consistently in time


It’s now finally 46th day of my exposure
And m freaking out with fear on doing hiv test


Does it necessary to go for test ? Pls help me out
By any chance can pep medicine will leads to wrong positiveresult ?

3
Questions About Treatment & Side Effects / Re: Update on switch to Dovato from Biktarvy
« Last post by Dogman on Today at 12:03:33 am »
I'll bore everyone with my 6 monthly check up, now 18 months into switch to Dovato from Bik - after 6 months on Bik (treatment start) - and I promise not to mention my CD4's. My VL is still UD, all my other numbers were pretty good, no big red triangles with an exclamation mark. I have really had 0 side effects that I'm aware of, apart from very minor sleep issues.  I'm just posting this as people who have or are considering a switch often like to see how it's gone for others. Hope everyone is doing ok.
4
Living With HIV / Re: "HOPE DIES LAST"
« Last post by Tonny2 on Yesterday at 08:13:47 am »



                   ojo.            Hello there!… It is tough to be in the hospital not knowing if you are going to survive specially during the holidays, but you made it out of the hospital alive and you’re still here with us and I’m sure that you’re gonnabe around  for long time like Some of us  love ng time survivors whom for some reason, we are still here while others aren’t. just keep taking your metd as prescribed and live life at the fullest because, there is life after an HIV diagnosis…hugs
5
Off Topic Forum / Re: YouTube Links for the Day
« Last post by leatherman on December 06, 2024, 06:38:14 pm »
Quote from: Jim Allen on December 06, 2024, 04:53:24 pm
Misheard Lyrics
that was hilarious!!!
6
Off Topic Forum / Re: YouTube Links for the Day
« Last post by Jim Allen on December 06, 2024, 04:53:24 pm »
Misheard Lyrics
https://www.youtube.com/watch?v=7my5baoCVv8
7
Living With HIV / Re: Should i be worried?
« Last post by Bucklandbury on December 06, 2024, 09:40:42 am »
Quote from: Jim Allen on November 27, 2024, 02:36:04 pm
A touch of AIDS

Good old da.
8
Living With HIV / Re: CD4 count
« Last post by Bucklandbury on December 06, 2024, 09:37:04 am »
I have found this helpful.

Quote
The absolute CD4 count usually corresponds to the CD4 percentages. A CD4 percentage of greater than 29% corresponds to an absolute count of more than 500 cells/microliters, 14% to 28% corresponds to an absolute count between 200 and 500 cells/microliters, and less than 14% corresponds to an absolute count of fewer than 200 cells/microliters.

Source:

https://www.ncbi.nlm.nih.gov/books/NBK470231/
9
Research News & Studies / Re: Checkpoint Immunotherapy Is Safe for HIV-Positive People With Cancer
« Last post by ad2san on December 06, 2024, 09:11:58 am »
Hello Jim, thanks for your post. I had one TURB https://en.wikipedia.org/wiki/Transurethral_resection_of_the_prostate already end of November and will undergo a new one early January to finish some cleaning. Good news is that the tumors, although more numerous than expected is of non invasive and non agressive type (Ta G1 Low) ... so after the 2nd TURB and a round of Chemotherapy I will be fixed  :)

I have my planned appointment for HIV in January too, I am curious to see how the TURB worked on the laboratory results ... I am having night sweats twice a week since the chirurgy, never had this before, I guess there is some stuff happening ...
Cheers
10
Living With HIV / Re: CD4 count
« Last post by Jim Allen on December 06, 2024, 07:53:03 am »
Quote
but coming down to 359 is dangerously close to unhealthy territory.

Indeed. It's close to the start of the treatment threshold of the "wait and see" era of this pandemic, thankfully that's over now and we know the sad outcomes that time had. Nowadays, if it was someone newly diagnosed and they had a CD4 < 350 cells, it's already considered a "Late HIV diagnosis" and they want to continue to reduce those. 

Quote
This is NOT the article I was referring to, but it does go into some changes in thoughts on CD4/CD8 ratios. But I do recall reading an article that mentioned that absolute CD4 numbers aren't rock solid to represent immune health. I believe it was an article on lymphoma in PLWH and Non-HIV populations. Will keep looking.

I read it including their references. My thoughts are, that this isn't really new or a change in thoughts. Neither is the idea that a certain % of HIV-negative people that belong to other population groups also have inverted numbers, or that regardless of rebounding of CD4/CD8 counts we as a group have ongoing risks that are higher than the average for certain things but thankfully were also screened more often for them.

CD4 testing at diagnosis helps as those with very low counts or % require prophylaxis, screening, and pre-emptive treatment to avert morbidity and mortality. It also helps us understand what groups of people are testing late etc.  However, beyond that CD4/CD8 counts post-initial diagnosis today is largely irrelevant.

Counts were already less focused on 15 years ago, looking more at the % instead as it is more stable. Now, in the past continued and frequent monitoring, focus and care made sense somewhat during the "Pre-HAART" or the "Wait and see" era of this pandemic but this topic largely belongs to the past now it's the "Treat all now" era.

The more recent change in thoughts & guidelines that jumps to my mind would be about a decade ago, when they started to stop looking at CD4 counts once the VL is suppressed, as it's rather irrelevant, a waste of resources to check them and you see more and more clinics reducing the frequency of CD4 count checks to 12 months instead of every 3-6 months.


https://forums.poz.com/index.php?topic=78134.0

https://www.hiv.va.gov/patient/diagnosis/labs-cd4-count.asp

https://i-base.info/qa/14384

https://i-base.info/ttfa/section-1/9-interpreting-cd4-results-cd4-count-and-cd4-percentage/

https://forums.poz.com/index.php?topic=2276.msg744247#msg744247

https://forums.poz.com/index.php?topic=77637.0

https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00444-3/fulltext


Quote from: leatherman on December 06, 2024, 06:56:12 am
the cd4 count is simply a count of how many cd4s you have. It is not a measure of the strength or quality of your immune system. The general rule of thought is that MORE cd4s is better; although without being able to measure the strength/quality, that rule of thought is not always right. CD4s are also only one tiny part of your immune system as there are nearly 400 different types of CD cells.
I would like to see the source also. I have never hear of the "normal range" starting at less than 500. I do remember though in the late 90s the upper range being 800; but since a test for cd4 count wasn't even developed until the late 90s, the upper limit was something that changed as more data was collected.

I personally have told people that 400 wasn't the worst lower limit than having the 500 (taking into account that the count is not a measure of cd4 strength); but coming down to 359 is dangerously close to unhealthy territory. While the cd4 test doesn't measure strength, a result that is closer to "200 or less" does show that the HIV either has done or is doing a lot of damage to the immune system.

Unlike how the upper end of the cd4 normal range is just a number and is not reflective of strength of cd4s, I would never consider anything lower than 500 as the lower range limit. Anyone with a count below that is a patient that certainly could have HIV health related issues and is a patient who should be monitored more not less. Below 500 and as approaching 200 or less, the cd4 percentage should be consulted more than the absolute cd4 number concerning the patient's health.


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