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Author Topic: PLHIV and risk of heart attack  (Read 1961 times)

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Offline Jim Allen

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PLHIV and risk of heart attack
« on: June 23, 2019, 04:22:37 am »
Interesting read I suppose, not much that was not already known though.

https://www.poz.com/article/hiv-linked-doubled-risk-heart-attack

Quote
The average respective prevalence of various health conditions among those with and without HIV was: high blood pressure, 19% and 15%; smoking, 46% and 49%; irregular lipids, 22% and 18%; and diabetes, 6% and 7%. None of the differences within these pairs were statistically significant, meaning they could have been driven by chance.

Among the HIV-positive participants, the average prevalence of AIDS across all the studies was 27%. Sixty-seven percent of the partcipants with HIV had been exposed to antiretroviral treatment.

In the five cohorts that included people with HIV along with matched HIV-negative individuals, the average rate of heart attack per 1,000 cumulative years of follow-up was 5.0 cases among those with HIV and 2.8 cases among those without the virus. This meant that people with HIV had a 1.96-fold increased risk of heart attack compared with HIV-negative individuals.
 
Various lifestyle changes, in particular quitting smoking, may lower the risk of CVD among people with HIV. Additionally, the major ongoing clinical trial REPRIEVE is investigating whether the use of statins may mitigate the risk of CVD in the HIV population.
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